The natural and the inducible: Interleukin (IL)-17-producing γδ T cells

Trends in Immunology

Volumn 34, Issue 4, 2013, Pages 151-154

  Chien, Yueh hsiu ^a   Zeng, Xun ^a   Prinz, Immo ^b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

T cells; Interleukin 17; Rapid responding lymphocytes

Indexed keywords

CHEMOKINE RECEPTOR CCR6; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 4; RAG1 PROTEIN; SCAVENGER RECEPTOR; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR RELB; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANTIGEN SPECIFICITY; CYTOKINE PRODUCTION; EFFECTOR CELL; GAMMA DELTA T LYMPHOCYTE; GENE EXPRESSION; HUMAN; IMMUNITY; IMMUNOSTIMULATION; INNATE IMMUNITY; LYMPHOCYTE FUNCTION; NONHUMAN; REVIEW; THYMOCYTE;

ACUTE DISEASE; ANIMALS; CELL DIFFERENTIATION; HUMANS; IMMUNITY, CELLULAR; INFECTION; INTERLEUKIN-17; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS; TH17 CELLS;

EID: 84875840091     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2012.11.004     Document Type: Review

References (46)

1. Stark M.A., et al. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 2005, 22:285-294.
2. Weaver C.T., et al. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 2007, 25:821-852.
3. Bonneville M., et al. Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity. Nat. Rev. Immunol. 2010, 10:467-478.
4. Price A.E., et al. Marking and quantifying IL-17A-producing cells in vivo. PLoS ONE 2012, 7:e39750.
5. Kapsenberg M.L. Gammadelta T cell receptors without a job. Immunity 2009, 31:181-183.
6. Hamada S., et al. IL-17A produced by gammadelta T cells plays a critical role in innate immunity against listeria monocytogenes infection in the liver. J. Immunol. 2008, 181:3456-3463.
7. Lockhart E., et al. IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J. Immunol. 2006, 177:4662-4669.
8. Haas J.D., et al. Development of interleukin-17-producing gammadelta T cells is restricted to a functional embryonic wave. Immunity 2012, 37:48-59.
9. Gray E.E., et al. Cutting edge: identification of a motile IL-17-producing gammadelta T cell population in the dermis. J. Immunol. 2011, 186:6091-6095.
10. Cai Y., et al. Pivotal role of dermal IL-17-producing gammadelta T cells in skin inflammation. Immunity 2011, 35:596-610.
11. Sumaria N., et al. Cutaneous immunosurveillance by self-renewing dermal gammadelta T cells. J. Exp. Med. 2011, 208:505-518.
12. Zeng X., et al. gammadelta T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response. Immunity 2012, 37:524-534.
13. Roark C.L., et al. Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells. J. Immunol. 2007, 179:5576-5583.
14. Ribot J.C., et al. CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets. Nat. Immunol. 2009, 10:427-436.
15. Shibata K., et al. Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers. J. Immunol. 2008, 181:5940-5947.
16. Haas J.D., et al. CCR6 and NK1.1 distinguish between IL-17A and IFN-gamma-producing gammadelta effector T cells. Eur. J. Immunol. 2009, 39:3488-3497.
17. Smith E., et al. T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo. J. Immunol. 2009, 183:5685-5693.
18. Jensen K.D., et al. Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma. Immunity 2008, 29:90-100.
19. Turchinovich G., Hayday A.C. Skint-1 identifies a common molecular mechanism for the development of interferon-gamma-secreting versus interleukin-17-secreting gammadelta T cells. Immunity 2011, 35:59-68.
20. Grigoriadou K., et al. Most IL-4-producing gamma delta thymocytes of adult mice originate from fetal precursors. J. Immunol. 2003, 171:2413-2420.
21. Kreslavsky T., et al. TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:12453-12458.
22. Felices M., et al. Tec kinase Itk in gammadelta T cells is pivotal for controlling IgE production in vivo. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:8308-8313.
23. Do J.S., et al. Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism. J. Immunol. 2010, 184:1675-1679.
24. Powolny-Budnicka I., et al. RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in gammadelta T cells. Immunity 2011, 34:364-374.
25. Laird R.M., et al. Unexpected role for the B cell-specific Src family kinase B lymphoid kinase in the development of IL-17-producing gammadelta T cells. J. Immunol. 2010, 185:6518-6527.
26. Shibata K., et al. Notch-Hes1 pathway is required for the development of IL-17-producing {gamma}{delta} T cells. Blood 2011, 118:586-593.
27. Petermann F., et al. gammadelta T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism. Immunity 2010, 33:351-363.
28. Hayes S.M., Laird R.M. Genetic requirements for the development and differentiation of interleukin-17-producing gammadelta T cells. Crit. Rev. Immunol. 2012, 32:81-95.
29. Raifer H., et al. Unlike alphabeta T cells, gammadelta T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22. Eur. J. Immunol. 2012, 10.1002/eji.201142155.
30. Kisielow J., et al. SCART scavenger receptors identify a novel subset of adult gammadelta T cells. J. Immunol. 2008, 181:1710-1716.
31. Narayan K., et al. Intrathymic programming of effector fates in three molecularly distinct gammadelta T cell subtypes. Nat. Immunol. 2012, 13:511-518.
32. Garman R.D., et al. Diversity, rearrangement, and expression of murine T cell gamma genes. Cell 1986, 45:733-742.
33. Heilig J.S., Tonegawa S. Diversity of murine gamma genes and expression in fetal and adult T lymphocytes. Nature 1986, 322:836-840.
34. Duber S., et al. Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells. Blood 2009, 114:4960-4967.
35. Simonian P.L., et al. IL-17A-expressing T cells are essential for bacterial clearance in a murine model of hypersensitivity pneumonitis. J. Immunol. 2009, 182:6540-6549.
36. Crowley M.P., et al. A population of murine gammadelta T cells that recognize an inducible MHC class Ib molecule. Science 2000, 287:314-316.
37. Blattman J.N., et al. Estimating the precursor frequency of naive antigen-specific CD8 T cells. J. Exp. Med. 2002, 195:657-664.
38. Marzo A.L., et al. Initial T cell frequency dictates memory CD8+ T cell lineage commitment. Nat. Immunol. 2005, 6:793-799.
39. Moon J.J., et al. Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity 2007, 27:203-213.
40. Duan J., et al. Microbial colonization drives expansion of IL-1 receptor 1-expressing and IL-17-producing gamma/delta T cells. Cell Host Microbe 2010, 7:140-150.
41. Flanagan W.M., et al. Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature 1991, 352:803-807.
42. Sutton C.E., et al. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 2009, 31:331-341.
43. Sprent J., Surh C.D. Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells. Nat. Immunol. 2011, 12:478-484.
44. Hayakawa K., et al. Isolation of high-affinity memory B cells: phycoerythrin as a probe for antigen-binding cells. Proc. Natl. Acad. Sci. U.S.A. 1987, 84:1379-1383.
45. Maruyama M., et al. Memory B-cell persistence is independent of persisting immunizing antigen. Nature 2000, 407:636-642.
46. Pape K.A., et al. Different B cell populations mediate early and late memory during an endogenous immune response. Science 2011, 331:1203-1207.