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Volumn 10, Issue 3, 2015, Pages

Effect of fatty acids on human bone marrow mesenchymal stem cell energy metabolism and survival

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ISOCITRATE DEHYDROGENASE; LDH A PROTEIN; OLEIC ACID; PALMITIC ACID; PGAM1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; FATTY ACID; PALMITIC ACID DERIVATIVE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

EID: 84928922694     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120257     Document Type: Article
Times cited : (56)

References (46)
  • 1
    • 81855182158 scopus 로고    scopus 로고
    • Death and inflammation following somatic cell transplantation
    • 21533908
    • Copland IB, Galipeau J. Death and inflammation following somatic cell transplantation. Semin Immunopathol. 2011;33:535-550. doi: 10.1007/s00281-011-0274-8 PMID: 21533908
    • (2011) Semin Immunopathol. , vol.33 , pp. 535-550
    • Copland, I.B.1    Galipeau, J.2
  • 2
    • 77955900387 scopus 로고    scopus 로고
    • Guided cardiopoiesis enhances therapeutic benefit of bone marrow human mesenchymal stem cells in chronic myocardial infarction
    • 20723802
    • Behfar A, Yamada S, Crespo-Diaz R, Nesbitt JJ, Rowe LA, Perez-Terzic C, et al. Guided cardiopoiesis enhances therapeutic benefit of bone marrow human mesenchymal stem cells in chronic myocardial infarction. J Am Coll Cardiol. 2010;56:721-734. doi: 10.1016/j.jacc.2010.03.066 PMID: 20723802
    • (2010) J Am Coll Cardiol. , vol.56 , pp. 721-734
    • Behfar, A.1    Yamada, S.2    Crespo-Diaz, R.3    Nesbitt, J.J.4    Rowe, L.A.5    Perez-Terzic, C.6
  • 3
    • 0141796313 scopus 로고    scopus 로고
    • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
    • 12910262
    • Mangi AA, Noiseux N, Kong D, He H, Rezvani M, Ingwall JS, et al. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med. 2003;9:1195-1201. PMID: 12910262
    • (2003) Nat Med. , vol.9 , pp. 1195-1201
    • Mangi, A.A.1    Noiseux, N.2    Kong, D.3    He, H.4    Rezvani, M.5    Ingwall, J.S.6
  • 4
    • 33646676295 scopus 로고    scopus 로고
    • The effects of mesenchymal stem cells transduced with Akt in a porcine myocardial infarction model
    • 16563361
    • Lim SY, Kim YS, Ahn Y, Jeong MH, Hong MH, Joo SY, et al. The effects of mesenchymal stem cells transduced with Akt in a porcine myocardial infarction model. Cardiovasc Res. 2006;70:530-542. PMID: 16563361
    • (2006) Cardiovasc Res. , vol.70 , pp. 530-542
    • Lim, S.Y.1    Kim, Y.S.2    Ahn, Y.3    Jeong, M.H.4    Hong, M.H.5    Joo, S.Y.6
  • 5
    • 34547901409 scopus 로고    scopus 로고
    • Bcl-2 engineered MSCs inhibited apoptosis and improved heart function
    • 17478584
    • Li W, Ma N, Ong LL, Nesselmann C, Klopsch C, Ladilov Y, et al. Bcl-2 engineered MSCs inhibited apoptosis and improved heart function. Stem Cells. 2007;25:2118-2127. PMID: 17478584
    • (2007) Stem Cells. , vol.25 , pp. 2118-2127
    • Li, W.1    Ma, N.2    Ong, L.L.3    Nesselmann, C.4    Klopsch, C.5    Ladilov, Y.6
  • 6
    • 61949313815 scopus 로고    scopus 로고
    • Fate of culture-expanded mesenchymal stem cells in the microvasculature: In vivo observations of cell kinetics
    • 19096027
    • Toma C, Wagner WR, Bowry S, Schwartz A, Villanueva F. Fate of culture-expanded mesenchymal stem cells in the microvasculature: in vivo observations of cell kinetics. Circ Res. 2009;104:398-402. doi: 10.1161/CIRCRESAHA.108.187724 PMID: 19096027
    • (2009) Circ Res. , vol.104 , pp. 398-402
    • Toma, C.1    Wagner, W.R.2    Bowry, S.3    Schwartz, A.4    Villanueva, F.5
  • 7
    • 77949267064 scopus 로고    scopus 로고
    • Glycolytic network restructuring integral to the energetics of embryonic stem cell cardiac differentiation
    • 20045004
    • Chung S, Arrell DK, Faustino RS, Terzic A, Dzeja PP. Glycolytic network restructuring integral to the energetics of embryonic stem cell cardiac differentiation. J Mol Cell Cardiol. 2010;48:725-734. doi: 10. 1016/j.yjmcc.2009.12.014 PMID: 20045004
    • (2010) J Mol Cell Cardiol. , vol.48 , pp. 725-734
    • Chung, S.1    Arrell, D.K.2    Faustino, R.S.3    Terzic, A.4    Dzeja, P.P.5
  • 9
    • 33846002728 scopus 로고    scopus 로고
    • A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
    • 17222789
    • Bonnet S, Archer SL, Allalunis-Turner J, Haromy A, Beaulieu C, Thompson R, et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell. 2007;11:37-51. PMID: 17222789
    • (2007) Cancer Cell. , vol.11 , pp. 37-51
    • Bonnet, S.1    Archer, S.L.2    Allalunis-Turner, J.3    Haromy, A.4    Beaulieu, C.5    Thompson, R.6
  • 10
    • 77955635790 scopus 로고    scopus 로고
    • Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension
    • 20702857
    • Sutendra G, Bonnet S, Rochefort G, Haromy A, Folmes KD, Lopaschuk GD, et al. Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension. Sci Transl Med. 2010;2:44ra58. doi: 10.1126/scitranslmed.3001327 PMID: 20702857
    • (2010) Sci Transl Med. , vol.2 , pp. 44ra58
    • Sutendra, G.1    Bonnet, S.2    Rochefort, G.3    Haromy, A.4    Folmes, K.D.5    Lopaschuk, G.D.6
  • 11
    • 38049120264 scopus 로고    scopus 로고
    • Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization
    • 17855623
    • Pecqueur C, Bui T, Gelly C, Hauchard J, Barbot C, Bouillaud F, et al. Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization. FASEB J. 2008;22:9-18. PMID: 17855623
    • (2008) FASEB J. , vol.22 , pp. 9-18
    • Pecqueur, C.1    Bui, T.2    Gelly, C.3    Hauchard, J.4    Barbot, C.5    Bouillaud, F.6
  • 12
    • 84907314187 scopus 로고    scopus 로고
    • Mitochondrial remodeling in hepatic differentiation and dedifferentiation
    • 25084555
    • Wanet A, Remacle N, Najar M, Sokal E, Arnould T, Najimi M, et al. Mitochondrial remodeling in hepatic differentiation and dedifferentiation. Int J Biochem Cell Biol. 2014;54:174-185. doi: 10.1016/j.biocel. 2014.07.015 PMID: 25084555
    • (2014) Int J Biochem Cell Biol. , vol.54 , pp. 174-185
    • Wanet, A.1    Remacle, N.2    Najar, M.3    Sokal, E.4    Arnould, T.5    Najimi, M.6
  • 13
    • 0001221508 scopus 로고
    • On respiratory impairment in cancer cells
    • 13351639
    • Warburg O. On respiratory impairment in cancer cells. Science. 1956;124:269-270. PMID: 13351639
    • (1956) Science. , vol.124 , pp. 269-270
    • Warburg, O.1
  • 16
    • 84878679199 scopus 로고    scopus 로고
    • A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
    • 23685455
    • Kaplon J, Zheng L, Meissl K, Chaneton B, Selivanov VA, Mackay G, et al. A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence. Nature. 2013;498:109-112. doi: 10.1038/nature12154 PMID: 23685455
    • (2013) Nature. , vol.498 , pp. 109-112
    • Kaplon, J.1    Zheng, L.2    Meissl, K.3    Chaneton, B.4    Selivanov, V.A.5    Mackay, G.6
  • 17
    • 84863111875 scopus 로고    scopus 로고
    • Human embryonic stem cells and embryonal carcinoma cells have overlapping and distinct metabolic signatures
    • 22768158
    • Abu Dawud R, Schreiber K, Schomburg D, Adjaye J. Human embryonic stem cells and embryonal carcinoma cells have overlapping and distinct metabolic signatures. PLoS One. 2012;7:e39896. doi: 10. 1371/journal.pone.0039896 PMID: 22768158
    • (2012) PLoS One. , vol.7 , pp. e39896
    • Abu Dawud, R.1    Schreiber, K.2    Schomburg, D.3    Adjaye, J.4
  • 18
    • 84906080047 scopus 로고    scopus 로고
    • Metabolic regulation of stem cell function
    • 24697828
    • Burgess RJ, Agathocleous M, Morrison SJ. Metabolic regulation of stem cell function. J Intern Med. 2014;276:12-24. doi: 10.1111/joim.12247 PMID: 24697828
    • (2014) J Intern Med. , vol.276 , pp. 12-24
    • Burgess, R.J.1    Agathocleous, M.2    Morrison, S.J.3
  • 19
    • 84902172412 scopus 로고    scopus 로고
    • Bone marrow endosteal mesenchymal progenitors depend on HIF factors for maintenance and regulation of hematopoiesis
    • 24936467
    • Guarnerio J, Coltella N, Ala U, Tonon G, Pandolfi PP, Bernardi R. Bone marrow endosteal mesenchymal progenitors depend on HIF factors for maintenance and regulation of hematopoiesis. Stem Cell Reports. 2014;2:794-809. doi: 10.1016/j.stemcr.2014.04.002 PMID: 24936467
    • (2014) Stem Cell Reports. , vol.2 , pp. 794-809
    • Guarnerio, J.1    Coltella, N.2    Ala, U.3    Tonon, G.4    Pandolfi, P.P.5    Bernardi, R.6
  • 20
    • 47949101704 scopus 로고    scopus 로고
    • Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment
    • 18308942
    • Mylotte LA, Duffy AM, Murphy M, O'Brien T, Samali A, Barry F, et al. Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment. Stem Cells. 2008;26:1325-1336. doi: 10.1634/stemcells.2007-1072 PMID: 18308942
    • (2008) Stem Cells. , vol.26 , pp. 1325-1336
    • Mylotte, L.A.1    Duffy, A.M.2    Murphy, M.3    O'Brien, T.4    Samali, A.5    Barry, F.6
  • 21
    • 84898970894 scopus 로고    scopus 로고
    • Concise review: Regulation of stem cell proliferation and differentiation by essential fatty acids and their metabolites
    • 24356924
    • Kang JX, Wan JB, He C. Concise review: Regulation of stem cell proliferation and differentiation by essential fatty acids and their metabolites. Stem Cells. 2014;32:1092-1098. doi: 10.1002/stem.1620 PMID: 24356924
    • (2014) Stem Cells. , vol.32 , pp. 1092-1098
    • Kang, J.X.1    Wan, J.B.2    He, C.3
  • 22
    • 79952312698 scopus 로고    scopus 로고
    • Increased lipogenesis, induced by AKTmTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma
    • 21147110
    • Calvisi DF, Wang C, Ho C, Ladu S, Lee SA, Mattu S, et al. Increased lipogenesis, induced by AKTmTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma. Gastroenterology. 2011;140:1071-1083. doi: 10.1053/j.gastro.2010.12.006 PMID: 21147110
    • (2011) Gastroenterology , vol.140 , pp. 1071-1083
    • Calvisi, D.F.1    Wang, C.2    Ho, C.3    Ladu, S.4    Lee, S.A.5    Mattu, S.6
  • 23
    • 56949099962 scopus 로고    scopus 로고
    • Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma
    • 19008011
    • Yamashita T, Honda M, Takatori H, Nishino R, Minato H, Takamura H, et al. Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma. J Hepatol. 2009;50:100-110. doi: 10.1016/j.jhep. 2008.07.036 PMID: 19008011
    • (2009) J Hepatol. , vol.50 , pp. 100-110
    • Yamashita, T.1    Honda, M.2    Takatori, H.3    Nishino, R.4    Minato, H.5    Takamura, H.6
  • 24
    • 83755178091 scopus 로고    scopus 로고
    • Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of alpha-ketoglutarate to citrate to support cell growth and viability
    • 22106302
    • Wise DR, Ward PS, Shay JE, Cross JR, Gruber JJ, Sachdeva UM, et al. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of alpha-ketoglutarate to citrate to support cell growth and viability. Proc Natl Acad Sci U S A. 2011;108:19611-19616. doi: 10.1073/pnas.1117773108 PMID: 22106302
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , pp. 19611-19616
    • Wise, D.R.1    Ward, P.S.2    Shay, J.E.3    Cross, J.R.4    Gruber, J.J.5    Sachdeva, U.M.6
  • 25
    • 20544449673 scopus 로고    scopus 로고
    • The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation
    • 15806154
    • Buzzai M, Bauer DE, Jones RG, Deberardinis RJ, Hatzivassiliou G, Elstrom RL, et al. The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation. Oncogene. 2005;24:4165-4173. PMID: 15806154
    • (2005) Oncogene. , vol.24 , pp. 4165-4173
    • Buzzai, M.1    Bauer, D.E.2    Jones, R.G.3    Deberardinis, R.J.4    Hatzivassiliou, G.5    Elstrom, R.L.6
  • 26
    • 79956326256 scopus 로고    scopus 로고
    • Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
    • 21576264
    • Zaugg K, Yao Y, Reilly PT, Kannan K, Kiarash R, Mason J, et al. Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes Dev. 2011;25:1041-1051. doi: 10.1101/gad.1987211 PMID: 21576264
    • (2011) Genes Dev. , vol.25 , pp. 1041-1051
    • Zaugg, K.1    Yao, Y.2    Reilly, P.T.3    Kannan, K.4    Kiarash, R.5    Mason, J.6
  • 27
  • 28
    • 0024465886 scopus 로고
    • At physiologic albumin/oleate concentrations oleate uptake by isolated hepatocytes, cardiac myocytes, and adipocytes is a saturable function of the unbound oleate concentration. Uptake kinetics are consistent with the conventional theory
    • 2794064
    • Sorrentino D, Robinson RB, Kiang CL, Berk PD. At physiologic albumin/oleate concentrations oleate uptake by isolated hepatocytes, cardiac myocytes, and adipocytes is a saturable function of the unbound oleate concentration. Uptake kinetics are consistent with the conventional theory. J Clin Invest. 1989;84:1325-1333. PMID: 2794064
    • (1989) J Clin Invest. , vol.84 , pp. 1325-1333
    • Sorrentino, D.1    Robinson, R.B.2    Kiang, C.L.3    Berk, P.D.4
  • 29
    • 1242269895 scopus 로고    scopus 로고
    • Trapping radioactive carbon dioxide during cellular metabolic assays under standard culture conditions: Description of a unique gas-capturing device
    • 14980785
    • Krieg RC, Liotta LA, Petricoin EF 3rd, Herrmann PC. Trapping radioactive carbon dioxide during cellular metabolic assays under standard culture conditions: description of a unique gas-capturing device. J Biochem Biophys Methods. 2004;58:119-124. PMID: 14980785
    • (2004) J Biochem Biophys Methods. , vol.58 , pp. 119-124
    • Krieg, R.C.1    Liotta, L.A.2    Petricoin, E.F.3    Herrmann, P.C.4
  • 30
    • 0015157071 scopus 로고
    • Quality control studies on fetal bovine serum used in tissue culture
    • 4131329
    • Boone CW, Mantel N, Caruso TD Jr., Kazam E, Stevenson RE. Quality control studies on fetal bovine serum used in tissue culture. In Vitro. 1971;7:174-189. PMID: 4131329
    • (1971) Vitro. , vol.7 , pp. 174-189
    • Boone, C.W.1    Mantel, N.2    Caruso, T.D.3    Kazam, E.4    Stevenson, R.E.5
  • 31
    • 84868632060 scopus 로고    scopus 로고
    • A PML-PPAR-delta pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
    • 22902876
    • Ito K, Carracedo A, Weiss D, Arai F, Ala U, Avigan DE, et al. A PML-PPAR-delta pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat Med. 2012;18:1350-1358. PMID: 22902876
    • (2012) Nat Med. , vol.18 , pp. 1350-1358
    • Ito, K.1    Carracedo, A.2    Weiss, D.3    Arai, F.4    Ala, U.5    Avigan, D.E.6
  • 32
    • 79959221064 scopus 로고    scopus 로고
    • Energy metabolism in human pluripotent stem cells and their differentiated counterparts
    • 21698063
    • Varum S, Rodrigues AS, Moura MB, Momcilovic O, Easley CAt, Ramalho-Santos J, et al. Energy metabolism in human pluripotent stem cells and their differentiated counterparts. PLoS One. 2011;6:e20914. doi: 10.1371/journal.pone.0020914 PMID: 21698063
    • (2011) PLoS One. , vol.6 , pp. e20914
    • Varum, S.1    Rodrigues, A.S.2    Moura, M.B.3    Momcilovic, O.4    Easley, C.At.5    Ramalho-Santos, J.6
  • 33
    • 49249086654 scopus 로고    scopus 로고
    • Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells
    • 18218821
    • Chen CT, Shih YR, Kuo TK, Lee OK, Wei YH. Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells. Stem Cells. 2008;26:960-968. doi: 10.1634/stemcells.2007-0509 PMID: 18218821
    • (2008) Stem Cells. , vol.26 , pp. 960-968
    • Chen, C.T.1    Shih, Y.R.2    Kuo, T.K.3    Lee, O.K.4    Wei, Y.H.5
  • 34
    • 79960666063 scopus 로고    scopus 로고
    • The metabolism of human mesenchymal stem cells during proliferation and differentiation
    • 21792913
    • Pattappa G, Heywood HK, De Bruijn JD, Lee DA. The metabolism of human mesenchymal stem cells during proliferation and differentiation. J Cell Physiol. 2011;226:2562-2570. doi: 10.1002/jcp. 22605 PMID: 21792913
    • (2011) J Cell Physiol. , vol.226 , pp. 2562-2570
    • Pattappa, G.1    Heywood, H.K.2    De Bruijn, J.D.3    Lee, D.A.4
  • 35
    • 84867795111 scopus 로고    scopus 로고
    • Palmitate causes endoplasmic reticulum stress and apoptosis in human mesenchymal stem cells: Prevention by AMPK activator
    • 22968644
    • Lu J, Wang Q, Huang L, Dong H, Lin L, Lin N, et al. Palmitate causes endoplasmic reticulum stress and apoptosis in human mesenchymal stem cells: prevention by AMPK activator. Endocrinology. 2012;153:5275-5284. doi: 10.1210/en. 2012-1418 PMID: 22968644
    • (2012) Endocrinology , vol.153 , pp. 5275-5284
    • Lu, J.1    Wang, Q.2    Huang, L.3    Dong, H.4    Lin, L.5    Lin, N.6
  • 36
    • 0035805629 scopus 로고    scopus 로고
    • Palmitate-induced apoptosis can occur through a ceramide-independent pathway
    • 11278654
    • Listenberger LL, Ory DS, Schaffer JE. Palmitate-induced apoptosis can occur through a ceramide-independent pathway. J Biol Chem. 2001;276:14890-14895. PMID: 11278654
    • (2001) J Biol Chem. , vol.276 , pp. 14890-14895
    • Listenberger, L.L.1    Ory, D.S.2    Schaffer, J.E.3
  • 38
    • 84862098783 scopus 로고    scopus 로고
    • Unsaturated fatty acids induce mesenchymal stem cells to increase secretion of angiogenic mediators
    • 22105830
    • Smith AN, Muffley LA, Bell AN, Numhom S, Hocking AM. Unsaturated fatty acids induce mesenchymal stem cells to increase secretion of angiogenic mediators. J Cell Physiol. 2012;227:3225-3233. doi: 10.1002/jcp. 24013 PMID: 22105830
    • (2012) J Cell Physiol. , vol.227 , pp. 3225-3233
    • Smith, A.N.1    Muffley, L.A.2    Bell, A.N.3    Numhom, S.4    Hocking, A.M.5
  • 39
    • 0032452225 scopus 로고    scopus 로고
    • Regulatory interactions between lipids and carbohydrates: The glucose fatty acid cycle after 35 years
    • 10095997
    • Randle PJ. Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years. Diabetes Metab Rev. 1998;14:263-283. PMID: 10095997
    • (1998) Diabetes Metab Rev. , vol.14 , pp. 263-283
    • Randle, P.J.1
  • 40
  • 41
    • 0033840188 scopus 로고    scopus 로고
    • Palmitate-mediated alterations in the fatty acid metabolism of rat neonatal cardiac myocytes
    • 10731449
    • Hickson-Bick DL, Buja LM, McMillin JB. Palmitate-mediated alterations in the fatty acid metabolism of rat neonatal cardiac myocytes. J Mol Cell Cardiol. 2000;32:511-519. PMID: 10731449
    • (2000) J Mol Cell Cardiol. , vol.32 , pp. 511-519
    • Hickson-Bick, D.L.1    Buja, L.M.2    McMillin, J.B.3
  • 42
    • 84891352333 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells
    • 24104879
    • De Meester C, Timmermans AD, Balteau M, Ginion A, Roelants V, Noppe G, et al. Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells. Cardiovasc Res. 2014;101:20-29. doi: 10.1093/cvr/cvt227 PMID: 24104879
    • (2014) Cardiovasc Res. , vol.101 , pp. 20-29
    • De Meester, C.1    Timmermans, A.D.2    Balteau, M.3    Ginion, A.4    Roelants, V.5    Noppe, G.6
  • 43
    • 0037445850 scopus 로고    scopus 로고
    • Mitochondrial effects with ceramide-induced cardiac apoptosis are different from those of palmitate
    • 12667483
    • Kong JY, Rabkin SW. Mitochondrial effects with ceramide-induced cardiac apoptosis are different from those of palmitate. Archives of Biochemistry and Biophysics. 2003;412:196-206. PMID: 12667483
    • (2003) Archives of Biochemistry and Biophysics. , vol.412 , pp. 196-206
    • Kong, J.Y.1    Rabkin, S.W.2
  • 45
    • 84873150798 scopus 로고    scopus 로고
    • Stem cell therapy in chronic obstructive pulmonary disease. Seeking the Prometheus effect
    • 23256721
    • Tzouvelekis A, Laurent G, Bouros D. Stem cell therapy in chronic obstructive pulmonary disease. Seeking the Prometheus effect. Curr Drug Targets. 2013;14:246-252. PMID: 23256721
    • (2013) Curr Drug Targets. , vol.14 , pp. 246-252
    • Tzouvelekis, A.1    Laurent, G.2    Bouros, D.3
  • 46
    • 84899654158 scopus 로고    scopus 로고
    • Discrepancies in autologous bone marrow stem cell trials and enhancement of ejection fraction (DAMASCENE): Weighted regression and meta-analysis
    • 24778175
    • Nowbar AN, Mielewczik M, Karavassilis M, Dehbi HM, Shun-Shin MJ, Jones S, et al. Discrepancies in autologous bone marrow stem cell trials and enhancement of ejection fraction (DAMASCENE): weighted regression and meta-analysis. BMJ. 2014;348:g2688. doi: 10.1136/bmj.g2688 PMID: 24778175
    • (2014) BMJ. , vol.348 , pp. g2688
    • Nowbar, A.N.1    Mielewczik, M.2    Karavassilis, M.3    Dehbi, H.M.4    Shun-Shin, M.J.5    Jones, S.6


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