SIRT1 mediates a primed response to immune challenge after traumatic lung injury

Journal of Trauma and Acute Care Surgery

Volumn 78, Issue 5, 2015, Pages 1034-1038

  Smith, Lane M ^a   Wells, Jonathan D ^b   Vachharajani, Vidula T ^a   Yoza, Barbara K ^b   McCall, Charles E ^b   Hoth, J Jason ^b  

^a Section on Molecular Medicine   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

immune priming; mice; Pulmonary contusion; second hit; SIRT1

Indexed keywords

LIPOPOLYSACCHARIDE; MESSENGER RNA; RESVERATROL; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA; RIBONUCLEOTIDE REDUCTASE; SIRT1 PROTEIN, MOUSE; STILBENE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO STUDY; GENE EXPRESSION; IMMUNE FUNCTION TEST; IMMUNE RESPONSE; IMMUNOBLOTTING; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SEPSIS; SURVIVAL; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BRONCHOALVEOLAR LAVAGE FLUID; C57BL MOUSE; CELLULAR IMMUNITY; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY; POLYMERASE CHAIN REACTION;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; IMMUNITY, CELLULAR; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LUNG; LUNG INJURY; MALE; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION; RIBONUCLEOTIDE REDUCTASES; RNA, MESSENGER; SIRTUIN 1; STILBENES;

EID: 84928902202     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0000000000000598     Document Type: Article

References (22)

1. Watkins TR, Nathens AB, Cooke CR, Psaty BM, Maier RV, Cuschieri J, Rubenfeld GD. Acute respiratory distress syndrome after trauma: development and validation of a predictive model. Crit Care Med. 2012;40: 2295-2303.
2. Hoth JJ,Wells JD, Jones SE, Yoza BK, McCall CE. Complement mediates a primed inflammatory response after traumatic lung injury. J Trauma Acute Care Surg. 2014;76:601-608.
3. Lasanianos NG, Kanakaris NK, Dimitriou R, Pape HC, Giannoudis PV. Second hit phenomenon: existing evidence of clinical implications. Injury. 2011;42:617-629.
4. Chang HC, Guarente L. SIRT1 and other sirtuins in metabolism. Trends Endocrinol Metab. 2014;25:138-145.
5. Liu TF, Brown CM, El Gazzar M, McPhail L, Millet P, Rao A, Vachharajani VT, Yoza BK, McCall CE. Fueling the flame: bioenergy couples metabolism and inflammation. J Leukoc Biol. 2012;92:499-507.
6. Kong S, McBurney MW, Fang D. Sirtuin 1 in immune regulation and autoimmunity. Immunol Cell Biol. 2012;90:6-13.
7. Granger A, Emambokus N. Focus on immunometabolism. Cell Metab. 2013;17:807.
8. Boutant M, Canto C. SIRT1 metabolic actions: integrating recent advances from mouse models. Mol Metab. 2014;3:5-18.
9. Hoth JJ, Martin RS, Yoza BK, Wells JD, Meredith JW, McCall CE. Pulmonary contusion primes systemic innate immunity responses. J Trauma. 2009;67:14-21.
10. Vachharajani VT, Liu T, Brown CM, Wang X, Buechler NL, Wells JD, Yoza BK, McCall CE. SIRT1 inhibition during the hypoinflammatory phenotype of sepsis enhances immunity and improves outcome. J Leukoc Biol. 2014;96:785-796.
11. Liu TF, Yoza BK, El Gazzar M, Vachharajani VT, McCall CE. NAD +-dependent SIRT1 deacetylase participates in epigenetic reprogramming during endotoxin tolerance. J Biol Chem. 2011;286:9856-9864.
12. Hoth JJ, Wells JD, Yoza BK, McCall CE. Innate immune response to pulmonary contusion: identification of cell type-specific inflammatory responses. Shock. 2012;37:385-391.
13. Hoth JJ, Wells JD, Brownlee NA, Hiltbold EM, Meredith JW, McCall CE, Yoza BK. Toll-like receptor 4-dependent responses to lung injury in a murine model of pulmonary contusion. Shock. 2009;31:376-381.
14. Hoth JJ, Wells JD, Hiltbold EM, McCall CE, Yoza BK. Mechanism of neutrophil recruitment to the lung after pulmonary contusion. Shock. 2011; 35:604-609.
15. Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem. 2005;280:17187-17195.
16. Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, et al. Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science. 2013;339:1216-1219.
17. Liu TF, Vachharajani VT, Yoza BK, McCall CE. NAD +-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response. J Biol Chem. 2012;287: 25758-25769.
18. Picard F, Kurtev M, ChungN, Topark-NgarmA, Senawong T, Machado De Oliveira R, Leid M, McBurney MW, Guarente L. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature. 2004;429:771-776.
19. Zhang Z, Lowry SF, Guarente L, Haimovich B. Roles of SIRT1 in the acute and restorative phases following induction of inflammation. J Biol Chem. 2010;285:41391-41401.
20. Liu TF, Vachharajani V, Millet P, Bharadwaj MS, Molina AJ, McCall CE. Sequential actions of SIRT1-RELB-SIRT3 coordinate nuclear-mitochondrial communication during immunometabolic adaptation to acute inflammation and sepsis. J Biol Chem. 2015;290:396-408.
21. Rajendrasozhan S, Yang SR, Kinnula VL, Rahman I. SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2008;177:861-870.
22. Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I. Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging. Am J Physiol Lung Cell Mol Physiol. 2007;292:L567YL576.