Prostaglandin transporter (PGT/SLCO2A1) protects the lung from bleomycin-induced fibrosis

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Nakanishi, Takeo ^a   Hasegawa, Yoshitaka ^a,c   Mimura, Reo ^a   Wakayama, Tomohiko ^a   Uetoko, Yuka ^a   Komori, Hisakazu ^a   Akanuma, Shin Ichi ^b   Hosoya, Ken Ichi ^b   Tamai, Ikumi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

^c TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; COLLAGEN; PHOSPHATE BUFFERED SALINE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROSTAGLANDIN E2; PROSTAGLANDIN TRANSPORTER; PROTEIN KINASE C DELTA; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; MESSENGER RNA; ORGANIC ANION TRANSPORTER; SLCO2A1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEOMYCIN-INDUCED PULMONARY FIBROSIS; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; FIBROSING ALVEOLITIS; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS CELL TYPE 1; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM CELL; LUNG FIBROSIS; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; DRUG EFFECTS; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LUNG; PATHOLOGY; WISTAR RAT;

MUS;

ANIMALS; BLEOMYCIN; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; DINOPROSTONE; GENE DELETION; GENE EXPRESSION REGULATION; LUNG; MALE; MICE, INBRED C57BL; ORGANIC ANION TRANSPORTERS; PULMONARY FIBROSIS; RATS, WISTAR; RNA, MESSENGER;

EID: 84928785323     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0123895     Document Type: Article

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