Fibroblast growth factor activation of the rat PRL promoter is mediated by PKCδ

Molecular Endocrinology

Volumn 15, Issue 9, 2001, Pages 1517-1528

  Jackson, Twila A ^a   Schweppe, Rebecca E ^a   Koterwas, David M ^a   Bradford, Andrew P ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; PROLACTIN; PROTEIN KINASE C; PROTEIN KINASE C DELTA; PROTEIN KINASE C INHIBITOR; ROTTLERIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE ACTIVATION; HYPOPHYSIS CELL; HYPOPHYSIS TUMOR; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION;

ACETOPHENONES; ADENOVIRIDAE; ANIMALS; BENZOPYRANS; CARBAZOLES; CULTURE MEDIA, SERUM-FREE; ENZYME ACTIVATION; ENZYME INHIBITORS; FIBROBLAST GROWTH FACTORS; IMMUNOBLOTTING; INDOLES; ISOENZYMES; MAP KINASE SIGNALING SYSTEM; NAPHTHALENES; PITUITARY NEOPLASMS; PROLACTIN; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; RATS; TUMOR CELLS, CULTURED;

EID: 0034830767     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.15.9.1517     Document Type: Article

References (58)

1. Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction
2. Structural and functional diversity in the FGF receptor multigene family
3. The ins and outs of fibroblast growth factors
4. Role of FGFs and FGF receptors in human carcinogenesis
5. Overexpression of growth factor-8 in human prostate cancer
6. Heparin-binding secretory transforming gene (hst) facilitates rat lactotrope cell tumorigenesis and induces prolactin gene expression
7. Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the ras/mitogen-activated protein kinase signaling pathway
8. Regulation of growth factor activation by proteoglycans: What is the role of the low affinity receptors
9. The heparin binding (fibroblast) growth factor family of proteins
10. Purification of a fibroblast growth factor from bovine pituitary
11. Basic fibroblast growth factor stimulates prolactin secretion from human anterior pituitary adenomas without affecting adenoma cell proliferation
12. Editorial: Fibroblast growth factors: What's in a name?
13. Stimulation of lactotrope differentiation in vitro by fibroblast growth factor
14. Circulating fibroblast growth factor-like substance in familial endocrine neoplasia type 1
15. Transforming DNA sequences present in human prolactin-secreting tumors
16. Altered expression of fibroblast growth factor receptors in human pituitary adenomas
17. The rat prolactin gene: A target for tissue-specific and hormone-dependent transcription factors
18. Functional components of fibroblast growth factor signal transduction in pituitary cells
19. Truncated, desensitization-defective neurokinin receptors mediate sustained MAP kinase activation, cell growth and transformation by a Ras-independent mechanism
20. Angiotensin II type 1 receptor signals through Raf-1 by a protein kinase C-dependent, Ras-independent mechanism
21. VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
22. PI 3-kinase γ and protein kinase C-ζ mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor
23. Both the catalytic and regulatory domains of protein kinase C chimeras modulate the proliferative properties of NIH 3T3 cells
24. Protein kinase C as a signal for exocytosis
25. Protein kinase C δ
26. Functional divergence of protein kinase C (PKC) family members. PKC γ differs from PKC α and -β II and nPKC ε in its competence to mediate-12-O-tetradecanoyl phorbol 13-acetate (TPA)-responsive transcriptional activation through a TPA-response element
27. Hormone- and phorbol ester-activated protein kinase C isozymes mediate a reorganization of the actin cytoskeleton associated with prolactin secretion in GH4C1 cells
28. Protein kinase C ζ isoform is critical for κ B-dependent promoter activation by sphingomyelinase
29. Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells
30. Stimulatory effect of phorbol diester on relaxin release by porcine luteal cells in culture
31. Identification of the functional components of the Ras signaling pathway regulating pituitary cell-specific gene expression
32. Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: Mapping of the essential c-Ets-1 domain
33. Protein kinase C isoenzymes: Divergence in signal transduction?
34. Limited proteolysis of protein kinase C subspecies by calcium-dependent neutral protease (calpain)
35. The Ras and protein kinase C signaling pathways are functionally antagonistic in GH4 neuroendocrine cells
36. Pharmacologic modulation of protein kinase C isozymes: The role of RACKs and subcellular localisation
37. The sevenfold way of PKC regulation
38. Subspecies-specific targeting mechanism of protein kinase C
39. Translocation of protein kinase Cε and protein kinase Cδ to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis
40. Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976
41. Rottlerin, a novel protein kinase inhibitor
42. Thyrotropin-releasing hormone stimulates MAP kinase activity in GH3 cells by divergent pathways
43. Mechanism of mitogen-activated protein kinase activation by gonadotropin-releasing hormone in the pituitary of αT3-1 cell line: Differential roles of calcium and protein kinase C
44. Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor
45. Differentiation of lactotrope precursor GHFT cells in response to FGF-2
46. Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis
47. Prolactinomas express human heparin-binding secretory transforming gene (hst) protein product: Marker of tumour invasiveness
48. A role for the mitogen-activated protein kinase in mediating the ability of thyrotropin-releasing hormone to stimulate the prolactin promoter
49. Developmental expression of PKC subspecieis in rat brain-pituitary axis
50. Overproduction of a Ca(2+)-independent protein kinase C isozyme, nPKC epsilon, increases the secretion of prolactin from thyrotropin-releasing hormone-stimulated rat pituitary GH4C1 cells
51. Effects of withdrawal of dopamine on translocation of PKC isozymes and prolactin secretion in rat lactotroph enriched pituitary cells
52. Differential activation of PKCδ and ε gene expression by GnRH in α T3-1 cells
53. Protein kinase C δ is essential for etoposide-induced apoptosis in salivary gland acinar cells
54. Mechanism of GnRH receptor signaling: Combinatorial cross-talk of Ca and PKC
55. Differential regulation of protein kinase C isoforms by thyrotropin releasing hormone in GH4C1 cells
56. Membrane targeting and cytoplasmic, sequestration in the spatiotemporal localization of human protein kinase Cα
57. The D2 dopamine receptor mediates inhibition of growth in GH4ZR7 cells: Involvement of protein kinase C epsilon
58. Evidence for the involvement of PKC in the inhibition of prolactin gene expression by TGFβ 2