Cloning of mouse prostaglandin transporter PGT cDNA: Species-specific substrate affinities

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 277, Issue 3 46-3, 1999, Pages

  Pucci, Michael L ^a   Bao, Yi ^a   Chan, Brenda ^a   Itoh, Shigekazu ^a   Lu, Run ^a   Copeland, Neal G ^b   Gilbert, Debra J ^b   Jenkins, Nancy A ^b   Schuster, Victor L ^a,c  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c Renal Division   (United States)

Author keywords

Biological transport; Carrier proteins; Interspecific mouse backcross mapping; Molecular cloning

Indexed keywords

COMPLEMENTARY DNA; PROSTAGLANDIN; PROSTAGLANDIN E2;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHROMOSOME 3; CHROMOSOME 9; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

EID: 0032875131     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1999.277.3.r734     Document Type: Article

References (35)

1. 3 receptor. Mol. Pharmacol. 51: 61-68, 1997.
2. Audoly, L., and R. M. Breyer. The second extracellular loop of the prostaglandin EP3 receptor is an essential determinant of ligand selectivity. J. Biol. Chem. 272: 13475-13478, 1997.
3. Bao, Y., M. Pucci, and V. L. Schuster. Immunocytochemical co-localization of the prostaglandin transporter PGT with cyclooxygenase-1 (cox-1) in rat kidney (Abstract). J. Am. Soc. Nephrol. 8: A1907, 1998.
4. 1α. Prostaglandins 21: 133-142, 1981.
5. Bates, E. J. Eicosanoids, fatty acids, and neutrophils: their relevance to the pathophysiology of disease. Prostaglandins Leukot. Essent. Fatty Acids 53: 75-86, 1995.
6. Bito, L. Z., and R. A. Baroody. Impermeability of rabbit erythrocytes to prostaglandins. Am. J. Physiol. 229: 1580-1584, 1975.
7. Chan, B., Y. Bao, S. Itoh, R. Lu, and V. L. Schuster. Role of charged residues in the function of the prostaglandin transporter "PGT" (Abstract). J. Am. Soc. Nephrol. 7: A0252, 1996.
8. Chan, B. S., J. A. Satriano, M. Pucci, and V. L. Schuster. Mechanism of prostaglandin E2 transport across the plasma membrane of HeLa cells and Xenopus oocytes expressing the prostaglandin transporter "PGT". J. Biol. Chem. 273: 6689-6697, 1998.
9. Chan, B., J. A. Satriano, and V. L. Schuster. Cysteine 530 within membrane span 10 is located in the substrate binding region of the prostaglandin transporter PGT (Abstract). J. Am. Soc. Nephrol. 8: A0237, 1997.
10. Chang, C., M. Negishi, N. Nishigaki, and A. Ichikawa. Functional interaction of the carboxylic acid group of agonists and the arginine residue of the seventh transmembrane domain of prostaglandin E receptor EP3 subtype. Biochem. J. 322: 597-601, 1997.
11. Chang, C. S., M. Negishi, N. Nishigaki, and A. Ichikawa. Characterization of functional interaction of carboxylic acid group of agonists and arginine of the seventh transmembrane domains of four prostaglandin E receptor subtypes. Prostaglandins 54: 437-446, 1997.
12. Copeland, N. G., and N. A. Jenkins. Development and applications of a molecular genetic linkage map of the mouse genome. Trends Genet. 7: 113-118, 1991.
13. Epstein, M. Prostaglandins and the kidney (Abstract). Am. J. Med. 80: 84, 1986.
14. Fuerst, T. R., E. G. Niles, F. W. Studier, and B. Moss. Eukaryotic transient expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase. Proc. Natl. Acad. Sci. USA 83: 8122-8126, 1986.
15. Hasson, T., J. F. Skowron, D. J. Gilbert, K. B. Avraham, W. L. Perry, W. M. Bement, B. L. Anderson, E. H. Sherr, Z.-Y. Chen, L. A. Greene, D. C. Ward, D. P. Corey, M. S. Mooseker, N. G. Copeland, and N. A. Jenkins. Mapping of unconventional myosins in mouse and human. Genomics 36: 431-439, 1996.
16. +-glucose cotransporters (SGLT-1). Am. J. Physiol. 270 (Gastrointest. Liver Physiol. 33): G919-G926, 1996.
17. Huang, C., and H. H. Tai. Expression and site-directed mutagenesis of mouse prostaglandin E2 receptor EP3 subtype in insect cells. Biochem. J. 307: 493-498, 1995.
18. Itoh, S., R. Lu, Y. Bao, J. D. Morrow, L. J. Roberts, and V. L. Schuster. Structural determinants of substrates for the prostaglandin transporter PGT. Mol. Pharmacol. 50: 736-742, 1996.
19. Jenkins, N. A., N. G. Copeland, B. A. Taylor, and B. K. Lee. Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. J. Virol. 43: 26-36, 1982.
20. Kanai, N., R. Lu, J. A. Satriano, Y. Bao, A. W. Wolkoff, and V. L. Schuster. Identification and characterization of a prostaglandin transporter. Science 268: 866-869, 1995.
21. Kingsley, D. M., N. A. Jenkins, and N. G. Copeland. A molecular genetic linkage map of mouse chromosome 9 with regional localizations for the Gsta, T3g, Ets-1 and Ldrl loci. Genetics 123: 165-172, 1989.
22. Kozak, M. An analysis of vertebrate mRNA sequences: intimations of translational control. J. Cell Biol. 115: 887-903, 1991.
23. Kyte, J., and R. F. Doolittle. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157: 105-132, 1982.
24. Levine, L. Arachidonate Metabolism in Immunologic Systems. New York: Karger, 1988, Progress in Allergy. vol 44.
25. Lu, R., N. Kanai, Y. Bao, and V. L. Schuster. Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA(hPGT). J. Clin. Invest. 98: 1142-1149, 1996.
26. Lu, R. and V. L. Schuster. Molecular cloning of the gene for the human prostaglandin transporter hPGT: gene organization, promoter activity, and chromosomal localization. Biochem. Biophys. Res. Commun. 246: 805-812, 1998.
27. Negishi, M., A. Irie, Y. Sugimoto, T. Namba, and A. Ichikawa. Selective coupling of prostaglandin E receptor EP3D to Gi and Gs through interaction of alpha-carboxylic acid of agonist and arginine residue of seventh transmembrane domain. J. Biol. Chem. 270: 16122-16127, 1995.
28. Neri Serneri, G. G. Platelets, prostaglandins, and the cardiovascular system. In: Advances in Prostaglandin, Thromboxane, and Leukotriene Research, New York: Raven, 1985, vol. 13, p. 59-70.
29. +-dicarboxylate cotransporters, NaDC-1 and hNaDC-1. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F1093-F1099, 1996.
30. Poyser, N. L. The control of prostaglandin production by the endometrium in relation to luteolysis and menstruation. Prostaglandins Leukot. Essent. Fatty Acids 53: 147-195, 1997.
31. Sambrook, J., E. F. Fritsch, and T. Maniatis. Molecular Cloning: A Laboratory Manual (2nd ed.). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
32. Schuster, V. L. Molecular mechanisms of prostaglandin transport. Annu. Rev. Physiol. 60: 221-242, 1998.
33. Silverstein, F. E., D. Y. Graham, J. R. Senior, H. W. Davies, B. J. Struthers, and G. S. Geis. Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial. Ann. Intern. Med. 123: 241-249, 1995.
34. Uekama, K., F. Hirayama, H. Tanaka, and K. Takematsu. Partition behaviour and ion pair formation of some prostaglandins (Abstract). Chem. Pharm. Bull. (Tokyo) 26: F58, 1978.
35. Ulmann, A., L. Silvestre, L. Chemama, Y. Rezvani, M. Renault, C. J. Aguillaume, and E. E. Baulieu. Medical termination of early pregnancy with mifepristone (RU 486) followed by a prostaglandin analogue. Study in 16,369 women. Acta Obstet. Gynecol. Scand. 71: 278-283, 1992.