Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-β in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice

American Journal of Pathology

Volumn 158, Issue 4, 2001, Pages 1411-1422

  Keerthisingam, Carmel B ^a   Jenkins, R Gisli ^a   Harrison, Nicholas K ^b   Hernandez Rodriguez, Norma A ^c   Booth, Helen ^a   Laurent, Geoffrey J ^a   Hart, Stephen L ^d   Foster, Martyn L ^e   McAnulty, Robin J ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b MORRISTON HOSPITAL   (United Kingdom)

^c INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e Aventis Pharma Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; COLLAGEN; CYCLOOXYGENASE 2; MESSENGER RNA; PROSTAGLANDIN E2; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DRUG INDUCED DISEASE; ENZYME DEFICIENCY; HUMAN; HUMAN CELL; LUNG FIBROBLAST; LUNG FIBROSIS; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION;

EID: 0035070056     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64092-8     Document Type: Article

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