A clearance system for prostaglandin D2, a sleep-promoting factor, in cerebrospinal fluid: Role of the blood-cerebrospinal barrier transporters

Journal of Pharmacology and Experimental Therapeutics

Volumn 343, Issue 3, 2012, Pages 608-616

  Tachikawa, Masanori ^a,b   Tsuji, Kazuhiro ^a   Yokoyama, Reiji ^a   Higuchi, Takanori ^a   Ozeki, Go ^a   Yashiki, Ayane ^a   Akanuma, Shin Ichi ^a   Hayashi, Kazuyuki ^c   Nishiura, Akio ^c   Hosoya, Ken Ichi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c ONO PHARMACEUTICAL CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; CARRIER PROTEIN; INULIN; ORGANIC ANION TRANSPORTER 3; PROSTAGLANDIN D2; PROSTAGLANDIN TRANSPORTER; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD CEREBROSPINAL FLUID BARRIER; CHOROID PLEXUS; CLEARANCE; CONTROLLED STUDY; FEMALE; FLOW KINETICS; GUINEA PIG; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MOUSE; NEUROEPITHELIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; XENOPUS LAEVIS;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CHOROID PLEXUS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EPITHELIAL CELLS; FEMALE; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENTRICULAR; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED STRAINS; OOCYTES; ORGANIC ANION TRANSPORTERS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; PROSTAGLANDIN D2; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SLEEP; TISSUE DISTRIBUTION; XENOPUS LAEVIS;

EID: 84868664861     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.197012     Document Type: Article

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