메뉴 건너뛰기




Volumn 6, Issue 11, 2015, Pages 8676-8686

A novel role for microRNA-129-5p in inhibiting ovarian cancer cell proliferation and survival via direct suppression of transcriptional co-activators YAP and TAZ

Author keywords

Cell proliferation; miR 129 5p; Survival; TAZ; YAP

Indexed keywords

CISPLATIN; CONNECTIVE TISSUE GROWTH FACTOR; CYCLIN A; MICRORNA; MICRORNA 129 5P; UNCLASSIFIED DRUG; CTGF PROTEIN, HUMAN; HIPPO PROTEIN, HUMAN; MESSENGER RNA; MIRN129 MICRORNA, HUMAN; OLIGONUCLEOTIDE; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; RNA; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; WWTR1 PROTEIN, HUMAN; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

EID: 84928719762     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3254     Document Type: Article
Times cited : (70)

References (40)
  • 3
    • 0036365026 scopus 로고    scopus 로고
    • Current diagnosis and treatment modalities for ovarian cancer
    • Schwartz PE. Current diagnosis and treatment modalities for ovarian cancer. Cancer Treat Res. 2002; 107:99-118.
    • (2002) Cancer Treat Res , vol.107 , pp. 99-118
    • Schwartz, P.E.1
  • 4
    • 77953406082 scopus 로고    scopus 로고
    • Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth
    • Yallapu MM, Maher DM, Sundram V, Bell MC, Jaggi M, Chauhan SC. Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth. J Ovarian Res. 2010; 3:11.
    • (2010) J Ovarian Res , vol.3 , pp. 11
    • Yallapu, M.M.1    Maher, D.M.2    Sundram, V.3    Bell, M.C.4    Jaggi, M.5    Chauhan, S.C.6
  • 5
    • 68349155807 scopus 로고    scopus 로고
    • Ovarian carcinoma pathology and genetics: recent advances
    • Gilks CB, Prat J. Ovarian carcinoma pathology and genetics: recent advances. Hum Pathol. 2009; 40:1213-1223.
    • (2009) Hum Pathol , vol.40 , pp. 1213-1223
    • Gilks, C.B.1    Prat, J.2
  • 6
    • 77951784627 scopus 로고    scopus 로고
    • Ovarian cancer pathogenesis: a model in evolution
    • Karst AM, Drapkin R. Ovarian cancer pathogenesis: a model in evolution. J Oncol. 2010; 2010:932371.
    • (2010) J Oncol , vol.2010 , pp. 932371
    • Karst, A.M.1    Drapkin, R.2
  • 8
    • 23744458034 scopus 로고    scopus 로고
    • The hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating yorkie, the drosophila homolog of YAP
    • Huang J, Wu S, Barrera J, Matthews K, Pan D. The hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating yorkie, the drosophila homolog of YAP. Cell. 2005; 122:421-434.
    • (2005) Cell , vol.122 , pp. 421-434
    • Huang, J.1    Wu, S.2    Barrera, J.3    Matthews, K.4    Pan, D.5
  • 9
    • 41149098966 scopus 로고    scopus 로고
    • TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
    • Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL. TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol. 2008; 28:2426-2436.
    • (2008) Mol Cell Biol , vol.28 , pp. 2426-2436
    • Lei, Q.Y.1    Zhang, H.2    Zhao, B.3    Zha, Z.Y.4    Bai, F.5    Pei, X.H.6    Zhao, S.7    Xiong, Y.8    Guan, K.L.9
  • 11
    • 55549098921 scopus 로고    scopus 로고
    • Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
    • Oka T, Mazack V, Sudol M. Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J Biol Chem. 2008; 283:27534-27546.
    • (2008) J Biol Chem , vol.283 , pp. 27534-27546
    • Oka, T.1    Mazack, V.2    Sudol, M.3
  • 13
    • 67649412006 scopus 로고    scopus 로고
    • TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition
    • Zhang H, Liu CY, Zha ZY, Zhao B, Yao J, Zhao S, Xiong Y, Lei QY, Guan KL. TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. J Biol Chem. 2009; 284:13355-13362.
    • (2009) J Biol Chem , vol.284 , pp. 13355-13362
    • Zhang, H.1    Liu, C.Y.2    Zha, Z.Y.3    Zhao, B.4    Yao, J.5    Zhao, S.6    Xiong, Y.7    Lei, Q.Y.8    Guan, K.L.9
  • 14
    • 67649770134 scopus 로고    scopus 로고
    • TEADs mediate nuclear retention of TAZ to promote oncogenic transformation
    • Chan SW, Lim CJ, Loo LS, Chong YF, Huang C, Hong W. TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. J Biol Chem. 2009; 284:14347-14358.
    • (2009) J Biol Chem , vol.284 , pp. 14347-14358
    • Chan, S.W.1    Lim, C.J.2    Loo, L.S.3    Chong, Y.F.4    Huang, C.5    Hong, W.6
  • 15
    • 79953310106 scopus 로고    scopus 로고
    • Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF
    • Lai D, Ho KC, Hao Y, Yang X. Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Res. 2011; 71:2728-2738.
    • (2011) Cancer Res , vol.71 , pp. 2728-2738
    • Lai, D.1    Ho, K.C.2    Hao, Y.3    Yang, X.4
  • 16
    • 84893710162 scopus 로고    scopus 로고
    • The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity
    • Shimomura T, Miyamura N, Hata S, Miura R, Hirayama J , Nishina H. The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity. Biochem Biophys Res Commun. 2014; 443:917-923.
    • (2014) Biochem Biophys Res Commun , vol.443 , pp. 917-923
    • Shimomura, T.1    Miyamura, N.2    Hata, S.3    Miura, R.4    Hirayama, J.5    Nishina, H.6
  • 17
    • 84894489420 scopus 로고    scopus 로고
    • TR1 promotes cell proliferation and inhibits apoptosis through cyclin A and CTGF regulation in non-small cell lung cancer
    • Wang L, Chen Z, Wang Y, Chang D, Su L, Guo Y, Liu C. TR1 promotes cell proliferation and inhibits apoptosis through cyclin A and CTGF regulation in non-small cell lung cancer. Tumour Biol. 2014; 35:463-468.
    • (2014) Tumour Biol , vol.35 , pp. 463-468
    • Wang, L.1    Chen, Z.2    Wang, Y.3    Chang, D.4    Su, L.5    Guo, Y.6    Liu, C.7
  • 19
    • 79955638768 scopus 로고    scopus 로고
    • TAZ is a novel oncogene in non-small cell lung cancer
    • Zhou Z, Hao Y, Liu N, Raptis L, Tsao MS, Yang X. TAZ is a novel oncogene in non-small cell lung cancer. Oncogene. 2011; 30:2181-2186.
    • (2011) Oncogene , vol.30 , pp. 2181-2186
    • Zhou, Z.1    Hao, Y.2    Liu, N.3    Raptis, L.4    Tsao, M.S.5    Yang, X.6
  • 24
    • 84875263231 scopus 로고    scopus 로고
    • Regulation of Hippo signaling by EGFR-MAPK signaling through Ajuba family proteins
    • Reddy BV, Irvine KD. Regulation of Hippo signaling by EGFR-MAPK signaling through Ajuba family proteins. Dev Cell. 2013; 24:459-471.
    • (2013) Dev Cell , vol.24 , pp. 459-471
    • Reddy, B.V.1    Irvine, K.D.2
  • 25
    • 84873734231 scopus 로고    scopus 로고
    • Regulation of hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1
    • Fan R, Kim NG, Gumbiner BM. Regulation of hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1. Proc Natl Acad Sci U S A. 2013; 110:2569-2574.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 2569-2574
    • Fan, R.1    Kim, N.G.2    Gumbiner, B.M.3
  • 26
    • 84882746359 scopus 로고    scopus 로고
    • Molecular pathways: YAP and TAZ take center stage in organ growth and tumorigenesis
    • Piccolo S, Cordenonsi M, Dupont S. Molecular pathways: YAP and TAZ take center stage in organ growth and tumorigenesis. Clin Cancer Res. 2013; 19:4925-4930.
    • (2013) Clin Cancer Res , vol.19 , pp. 4925-4930
    • Piccolo, S.1    Cordenonsi, M.2    Dupont, S.3
  • 28
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 29
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature. 2004; 431:350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 31
    • 0043198388 scopus 로고    scopus 로고
    • Coupling cell growth, proliferation, and death. Hippo weighs in
    • Hay BA, Guo M. Coupling cell growth, proliferation, and death. Hippo weighs in. Dev Cell. 2003; 5:361-363.
    • (2003) Dev Cell , vol.5 , pp. 361-363
    • Hay, B.A.1    Guo, M.2
  • 32
    • 0141616617 scopus 로고    scopus 로고
    • Hippo promotes proliferation arrest and apoptosis in the salvador/warts pathway
    • Udan RS, Kango-Singh M, Nolo R, Tao C, Halder G. Hippo promotes proliferation arrest and apoptosis in the salvador/warts pathway. Nat Cell Biol. 2003; 5:914-920.
    • (2003) Nat Cell Biol , vol.5 , pp. 914-920
    • Udan, R.S.1    Kango-Singh, M.2    Nolo, R.3    Tao, C.4    Halder, G.5
  • 34
    • 84884703146 scopus 로고    scopus 로고
    • Mob as tumor suppressor is regulated by bantam microRNA through a feedback loop for tissue growth control
    • Zhang Y, Lai ZC. Mob as tumor suppressor is regulated by bantam microRNA through a feedback loop for tissue growth control. Biochem Biophys Res Commun. 2013; 439:438-442.
    • (2013) Biochem Biophys Res Commun , vol.439 , pp. 438-442
    • Zhang, Y.1    Lai, Z.C.2
  • 35
    • 33749242966 scopus 로고    scopus 로고
    • The bantam microRNA is a target of the hippo tumor-suppressor pathway
    • Nolo R, Morrison CM, Tao C, Zhang X, Halder G. The bantam microRNA is a target of the hippo tumor-suppressor pathway. Curr Biol. 2006; 16:1895-1904.
    • (2006) Curr Biol , vol.16 , pp. 1895-1904
    • Nolo, R.1    Morrison, C.M.2    Tao, C.3    Zhang, X.4    Halder, G.5
  • 37
    • 84863298936 scopus 로고    scopus 로고
    • An update on targeting hippo-YAP signaling in liver cancer
    • Liu AM, Xu Z, Luk JM. An update on targeting hippo-YAP signaling in liver cancer. Exp Opin Ther Targets. 2012; 16:243-247.
    • (2012) Exp Opin Ther Targets , vol.16 , pp. 243-247
    • Liu, A.M.1    Xu, Z.2    Luk, J.M.3
  • 39
    • 84891748709 scopus 로고    scopus 로고
    • The two faces of hippo: targeting the hippo pathway for regenerative medicine and cancer treatment
    • Johnson R, Halder G. The two faces of hippo: targeting the hippo pathway for regenerative medicine and cancer treatment. Nat Rev Drug Discov. 2014; 13:63-79.
    • (2014) Nat Rev Drug Discov , vol.13 , pp. 63-79
    • Johnson, R.1    Halder, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.