-
1
-
-
77954770827
-
Targeting YAP and hippo signaling pathway in liver cancer
-
Liu AM, Xu MZ, Chen J, et al. Targeting YAP and Hippo signaling pathway in liver cancer. Expert Opin Ther Targets 2010;14:855-68
-
(2010)
Expert Opin Ther Targets
, vol.14
, pp. 855-868
-
-
Liu, A.M.1
Xu, M.Z.2
Chen, J.3
-
2
-
-
77955868800
-
Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver
-
Benhamouche S, Curto M, Saotome I, et al. Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver. Genes Dev 2010;24:1718-30
-
(2010)
Genes Dev
, vol.24
, pp. 1718-1730
-
-
Benhamouche, S.1
Curto, M.2
Saotome, I.3
-
3
-
-
60849124241
-
Phase II trial of the combination of bevacizumab and erlotinib in patients who have advanced hepatocellular carcinoma
-
Thomas MB, Morris JS, Chadha R, et al. Phase II trial of the combination of bevacizumab and erlotinib in patients who have advanced hepatocellular carcinoma. J Clin Oncol 2009;27:843-50
-
(2009)
J Clin Oncol
, vol.27
, pp. 843-850
-
-
Thomas, M.B.1
Morris, J.S.2
Chadha, R.3
-
4
-
-
70350502865
-
Mst1 and mst2 maintain hepatocytequiescence and suppress hepatocellular carcinoma development through inactivation of the yap1 oncogene
-
Zhou D, Conrad C, Xia F, et al. Mst1 and Mst2 maintain hepatocytequiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 2009;16:425-38
-
(2009)
Cancer Cell
, vol.16
, pp. 425-438
-
-
Zhou, D.1
Conrad, C.2
Xia, F.3
-
5
-
-
76549124517
-
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
-
Lu L, Li Y, Kim SM, et al. Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci USA 2010;107:1437-42
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1437-1442
-
-
Lu, L.1
Li, Y.2
Kim, S.M.3
-
6
-
-
34047250808
-
RASSF1A Is Part of a Complex Similar to the Drosophila Hippo/Salvador/Lats Tumor-Suppressor Network
-
DOI 10.1016/j.cub.2007.02.055, PII S0960982207010640
-
Guo C, Tommasi S, Liu L, et al. RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network. Curr Biol 2007;17:700-5 (Pubitemid 46552245)
-
(2007)
Current Biology
, vol.17
, Issue.8
, pp. 700-705
-
-
Guo, C.1
Tommasi, S.2
Liu, L.3
Yee, J.-K.4
Dammann, R.5
Pfeifer, GerdP.6
-
7
-
-
77952336576
-
The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
-
Lee KP, Lee JH, Kim TS, et al. The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis. Proc Natl Acad Sci USA 2010;107:8248-53
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8248-8253
-
-
Lee, K.P.1
Lee, J.H.2
Kim, T.S.3
-
8
-
-
0032907439
-
Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
-
DOI 10.1038/5965
-
St John MA, Tao W, Fei X, et al. Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction. Nat Genet 1999;21:182-6 (Pubitemid 29070363)
-
(1999)
Nature Genetics
, vol.21
, Issue.2
, pp. 182-186
-
-
St John, M.A.R.1
Tao, W.2
Fei, X.3
Fukumoto, R.4
Carcangiu, M.L.5
Brownstein, D.G.6
Parlow, A.F.7
McGrath, J.8
Xu, T.9
-
9
-
-
20844449390
-
Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity
-
DOI 10.1038/sj.emboj.7600371
-
McPherson JP, Tamblyn L, Elia A, et al. Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity. Embo J 2004;23:3677-88 (Pubitemid 39336289)
-
(2004)
EMBO Journal
, vol.23
, Issue.18
, pp. 3677-3688
-
-
McPherson, J.P.1
Tamblyn, L.2
Elia, A.3
Migon, E.4
Shehabeldin, A.5
Matysiak-Zablocki, E.6
Lemmers, B.7
Salmena, L.8
Hakem, A.9
Fish, J.10
Kassam, F.11
Squire, J.12
Bruneau, B.G.13
Hande, M.P.14
Hakem, R.15
-
10
-
-
76649106069
-
MiR-372 regulates cell cycle and apoptosis of ags human gastric cancer cel line through direct regulation of LATS2
-
Cho WJ, Shin JM, Kim JS, et al. miR-372 regulates cell cycle and apoptosis of ags human gastric cancer cel line through direct regulation of LATS2. Mol Cells 2009;28:521-7
-
(2009)
Mol Cells
, vol.28
, pp. 521-527
-
-
Cho, W.J.1
Shin, J.M.2
Kim, J.S.3
-
11
-
-
67651045805
-
MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer
-
Lee KH, Goan YG, Hsiao M, et al. MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer. Exp Cell Res 2009;315:2529-38
-
(2009)
Exp Cell Res
, vol.315
, pp. 2529-2538
-
-
Lee, K.H.1
Goan, Y.G.2
Hsiao, M.3
-
12
-
-
73549095761
-
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCFbeta-TRCP
-
Zhao B, Li L, Tumaneng K, et al. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCFbeta-TRCP. Genes Dev 2010;24:72-85
-
(2010)
Genes Dev
, vol.24
, pp. 72-85
-
-
Zhao, B.1
Li, L.2
Tumaneng, K.3
-
13
-
-
80052350139
-
Pp1a-mediated dephosphorylation positively regulates yap2 activity
-
Wang P, Bai Y, Song B, et al. PP1A-mediated dephosphorylation positively regulates YAP2 activity. PLoS One 2011;6:e24288
-
(2011)
PLoS One
, vol.6
-
-
Wang, P.1
Bai, Y.2
Song, B.3
-
14
-
-
84859583470
-
Integrating developmental signals: A hippo in the (path)way
-
published online 29, August 2011; doi:10.1038/onc.2011.363
-
Mauviel A, Nallet-Staub F, Varelas X. Integrating developmental signals: a Hippo in the (path)way. Oncogene 2011;published online 29 August 2011; doi:10.1038/onc.2011.363
-
(2011)
Oncogene
-
-
Mauviel, A.1
Nallet-Staub, F.2
Varelas, X.3
-
15
-
-
77952116604
-
Structural and functional analysis of the yap-binding domain of human tead2
-
Tian W, Yu J, Tomchick DR, et al. Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc Natl Acad Sci USA 2010;107:7293-8
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7293-7298
-
-
Tian, W.1
Yu, J.2
Tomchick, D.R.3
-
16
-
-
76149138881
-
Structural insights into the YAP and. TEAD complex
-
Li Z, Zhao B, Wang P, et al. Structural insights into the YAP and. TEAD complex. Genes Dev 2010;24:235-40
-
(2010)
Genes Dev
, vol.24
, pp. 235-240
-
-
Li, Z.1
Zhao, B.2
Wang, P.3
-
17
-
-
78650895035
-
Angiomotin is a novel hippo pathway component that inhibits YAP oncoprotein
-
Zhao B, Li L, Lu Q, et al. Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev 2011;25:51-63
-
(2011)
Genes Dev
, vol.25
, pp. 51-63
-
-
Zhao, B.1
Li, L.2
Lu, Q.3
-
18
-
-
79953223677
-
Hippo pathway-independent restriction of TAZ and YAP by angiomotin
-
Chan SW, Lim CJ, Chong YF, et al. Hippo pathway-independent restriction of TAZ and YAP by angiomotin. J Biol Chem 2011;286:7018-26
-
(2011)
J Biol Chem
, vol.286
, pp. 7018-7026
-
-
Chan, S.W.1
Lim, C.J.2
Chong, Y.F.3
-
19
-
-
80053363788
-
Angiomotin family proteins are novel activators of the lats2 kinase tumor suppressor
-
Paramasivam M, Sarkeshik A, Yates JR III, et al. Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor. Mol Biol Cell 2011;22:3725-33
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3725-3733
-
-
Paramasivam, M.1
Sarkeshik, A.2
Yates Iii, J.R.3
-
20
-
-
78649892579
-
Functional complexes between yap2 and zo-2 are PDZ domain-dependent, and regulate yap2 nuclear localization and signalling
-
Oka T, Remue E, Meerschaert K, et al. Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling. Biochem J 2010; 432:461-72
-
(2010)
Biochem J
, vol.432
, pp. 461-472
-
-
Oka, T.1
Remue, E.2
Meerschaert, K.3
-
21
-
-
84855344741
-
Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of yap
-
Oka T, Schmitt AP, Sudol M. Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAP. Oncogene 2012;31:128-34
-
(2012)
Oncogene
, vol.31
, pp. 128-134
-
-
Oka, T.1
Schmitt, A.P.2
Sudol, M.3
-
22
-
-
77950626836
-
Microrna-375 targets hippo-signaling effector YAP in liver cancer and inhibits tumor properties
-
Liu AM, Poon RT, Luk JM. MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties. Biochem Biophys Res Commun 2010;394:623-7
-
(2010)
Biochem Biophys Res Commun
, vol.394
, pp. 623-627
-
-
Liu, A.M.1
Poon, R.T.2
Luk, J.M.3
-
23
-
-
79957465561
-
Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice
-
Kowalik MA, Saliba C, Pibiri M, et al. Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice. Hepatology 2011;53:2086-96
-
(2011)
Hepatology
, vol.53
, pp. 2086-2096
-
-
Kowalik, M.A.1
Saliba, C.2
Pibiri, M.3
|