Wuling San protects kidney dysfunction by inhibiting renal TLR4/MyD88 signaling and NLRP3 inflammasome activation in high fructose-induced hyperuricemic mice

Journal of Ethnopharmacology

Volumn 169, Issue , 2015, Pages 49-59

  Yang, Ying ^a   Zhang, Dong Mei ^a   Liu, Jia Hui ^a   Hu, Lin Shui ^b   Xue, Qiao Chu ^a   Ding, Xiao Qin ^a   Kong, Ling Dong ^a  

^a NANJING UNIVERSITY   (China)

^b Zhejiang Conba Pharmaceutical Co   (China)

Author keywords

Fructose; Hyperuricemia; Renal dysfunction; Renal inflammation; Wuling San

Indexed keywords

ALLOPURINOL; BREAST CANCER RESISTANCE PROTEIN; CHINESE DRUG; CREATININE; CRYOPYRIN; FRUCTOSE; GLUCOSE TRANSPORTER 9; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; ORGANIC ANION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; URATE TRANSPORTER; URATE TRANSPORTER 1; URIC ACID; WULING SAN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; HERBACEOUS AGENT; MYD88 PROTEIN, MOUSE; PLANT EXTRACT; TLR4 PROTEIN, MOUSE; WULINGSAN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CYTOKINE RELEASE; ELISA KIT; GLOMERULUS; HISTOPATHOLOGY; HYPERURICEMIA; KIDNEY DYSFUNCTION; MALE; MOUSE; NONHUMAN; RENAL PROTECTION; SIGNAL TRANSDUCTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UREA NITROGEN BLOOD LEVEL; URIC ACID BLOOD LEVEL; URINALYSIS; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; CHINESE MEDICINE; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; KIDNEY DISEASES; METABOLISM; PHYSIOLOGY;

MUS; POLYPORUS; PORIA;

ANIMALS; CARRIER PROTEINS; DRUGS, CHINESE HERBAL; FRUCTOSE; HYPERURICEMIA; KIDNEY DISEASES; MALE; MEDICINE, CHINESE TRADITIONAL; MICE; MICE, INBRED ICR; MYELOID DIFFERENTIATION FACTOR 88; PLANT EXTRACTS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84928644340     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.04.011     Document Type: Article

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