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Volumn 9, Issue 3, 2015, Pages 211-222

European consensus on the diagnosis and management of iron deficiency and anaemia in inflammatory bowel diseases

(14)  Dignass, Axel U a,m   Gasche, Christoph b   Bettenworth, Dominik c   Birgegård, Gunnar d   Danese, Silvio e   Gisbert, Javier P f   Gomollon, Fernando g   Iqbal, Tariq h   Katsanos, Konstantinos i   Koutroubakis, Ioannis j   Magro, Fernando k   Savoye, Guillaume l   Stein, Jürgen m   Vavricka, Stephan n  


Author keywords

Anaemia; Anaemia of chronic disease; Crohn's disease; Inflammatory bowel disease; Iron deficiency; Transferrin saturation; Ulcerative colitis

Indexed keywords

ANTIANEMIC AGENT; C REACTIVE PROTEIN; FERRITIN; FERROUS SULFATE; HEMOGLOBIN; INFLIXIMAB; IRON; TRANSFERRIN; TRACE ELEMENT; VITAMIN;

EID: 84928603336     PISSN: 18739946     EISSN: 18764479     Source Type: Journal    
DOI: 10.1093/ecco-jcc/jju009     Document Type: Article
Times cited : (473)

References (132)
  • 1
    • 17344386962 scopus 로고    scopus 로고
    • Anemia in IBD: the overlooked villain
    • Gasche C. Anemia in IBD: the overlooked villain. Inflamm Bowel Dis 2000;6:142-50
    • (2000) Inflamm Bowel Dis , vol.6 , pp. 142-150
    • Gasche, C.1
  • 2
    • 33845495855 scopus 로고    scopus 로고
    • Systematic review: managing anemia in Crohn's disease
    • Kulnigg S, Gasche C. Systematic review: managing anemia in Crohn's disease. Aliment Pharmacol Ther 2006;24:1507-23
    • (2006) Aliment Pharmacol Ther , vol.24 , pp. 1507-1523
    • Kulnigg, S.1    Gasche, C.2
  • 3
    • 43549115913 scopus 로고    scopus 로고
    • Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease
    • Gisbert JP, Gomollon F. Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease. Am J Gastroenterol 2008;103:1299-307
    • (2008) Am J Gastroenterol , vol.103 , pp. 1299-1307
    • Gisbert, J.P.1    Gomollon, F.2
  • 4
    • 78049527939 scopus 로고    scopus 로고
    • Diagnosis and management of iron deficiency anemia in patients with IBD
    • Stein J, Hartmann F, Dignass AU. Diagnosis and management of iron deficiency anemia in patients with IBD. Nat Rev Gastroenterol Hepatol 2010;7:599-610
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 599-610
    • Stein, J.1    Hartmann, F.2    Dignass, A.U.3
  • 5
  • 6
    • 30944445958 scopus 로고    scopus 로고
    • Economic burden of patients with anemia in selected diseases
    • Ershler WB, Chen K, Reyes EB, Dubois R. Economic burden of patients with anemia in selected diseases. Value Health 2005;8:629-38
    • (2005) Value Health , vol.8 , pp. 629-638
    • Ershler, W.B.1    Chen, K.2    Reyes, E.B.3    Dubois, R.4
  • 7
    • 38049048044 scopus 로고    scopus 로고
    • Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases
    • Gasche C, Berstad A, Befrits R, et al. Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases. Inflamm Bowel Dis 2007;13:1545-53
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1545-1553
    • Gasche, C.1    Berstad, A.2    Befrits, R.3
  • 9
    • 85019845400 scopus 로고    scopus 로고
    • Anonymous. Levels of evidence and grades of recommendation Accessed October 3, 2014
    • Anonymous. Levels of evidence and grades of recommendation. 2011. http://www.cebm.net/mod_product/design/files/CEBM-Levels-of-Evidence-2.1.pdf Accessed October 3, 2014
    • (2011)
  • 10
    • 0005091245 scopus 로고    scopus 로고
    • Report of a joint WHO/UNICEF/UNU consultation. Geneva:World Health Organization
    • WHO, UNICEF, UNU. Iron Deficiency Anemia: Assessment, Prevention and Control. Report of a joint WHO/UNICEF/UNU consultation. Geneva:World Health Organization; 1998
    • (1998) Iron Deficiency Anemia: Assessment, Prevention and Control
  • 11
    • 33344455954 scopus 로고    scopus 로고
    • The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration?
    • Beutler E, Waalen J. The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration? Blood 2006;107: 1747-50
    • (2006) Blood , vol.107 , pp. 1747-1750
    • Beutler, E.1    Waalen, J.2
  • 12
    • 0026752797 scopus 로고
    • Iron nutrition does not account for the hemoglobin differences between blacks and whites
    • Perry GS, Byers T, Yip R, Margen S. Iron nutrition does not account for the hemoglobin differences between blacks and whites. J Nutr 1992;122:1417-24
    • (1992) J Nutr , vol.122 , pp. 1417-1424
    • Perry, G.S.1    Byers, T.2    Yip, R.3    Margen, S.4
  • 13
    • 1842525048 scopus 로고    scopus 로고
    • Prevalence and outcomes of anemia in inflammatory bowel disease: a systematic review of the literature
    • Wilson A, Reyes E, Ofman J. Prevalence and outcomes of anemia in inflammatory bowel disease: a systematic review of the literature. Am J Med 2004;116 Suppl 7A:44S-9S
    • (2004) Am J Med , vol.116 , pp. 44S-49S
    • Wilson, A.1    Reyes, E.2    Ofman, J.3
  • 14
    • 76549094518 scopus 로고    scopus 로고
    • Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor-alpha treatment
    • Bergamaschi G, Di SA, Albertini R, et al. Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor-alpha treatment. Haematologica 2010;95:199-205
    • (2010) Haematologica , vol.95 , pp. 199-205
    • Bergamaschi, G.1    Di, S.A.2    Albertini, R.3
  • 15
    • 84857363244 scopus 로고    scopus 로고
    • Prevalence and management of anemia in children, adolescents, and adults with inflammatory bowel disease
    • Goodhand JR, Kamperidis N, Rao A, et al. Prevalence and management of anemia in children, adolescents, and adults with inflammatory bowel disease. Inflamm Bowel Dis 2012;18:513-9
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 513-519
    • Goodhand, J.R.1    Kamperidis, N.2    Rao, A.3
  • 16
    • 33144468326 scopus 로고    scopus 로고
    • European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis
    • Stange EF, Travis SP, Vermeire S, et al. European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis. Gut 2006;55 Suppl 1:i1-15
    • (2006) Gut , vol.55 , pp. i1-i15
    • Stange, E.F.1    Travis, S.P.2    Vermeire, S.3
  • 17
    • 33750624917 scopus 로고    scopus 로고
    • Vitamin B12 malabsorption in patients with limited ileal resection
    • Duerksen DR, Fallows G, Bernstein CN. Vitamin B12 malabsorption in patients with limited ileal resection. Nutrition 2006;22:1210-3
    • (2006) Nutrition , vol.22 , pp. 1210-1213
    • Duerksen, D.R.1    Fallows, G.2    Bernstein, C.N.3
  • 18
    • 14744278436 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005;352:1011-23
    • (2005) N Engl J Med , vol.352 , pp. 1011-1023
    • Weiss, G.1    Goodnough, L.T.2
  • 20
    • 80053130535 scopus 로고    scopus 로고
    • Diagnosing anemia in inflammatory bowel disease: beyond the established markers
    • Oustamanolakis P, Koutroubakis IE, Kouroumalis EA. Diagnosing anemia in inflammatory bowel disease: beyond the established markers. J Crohns Colitis 2011;5:381-91
    • (2011) J Crohns Colitis , vol.5 , pp. 381-391
    • Oustamanolakis, P.1    Koutroubakis, I.E.2    Kouroumalis, E.A.3
  • 22
    • 0037362778 scopus 로고    scopus 로고
    • Soluble transferrin receptor for the evaluation of erythropoiesis and iron status
    • Beguin Y. Soluble transferrin receptor for the evaluation of erythropoiesis and iron status. Clin Chim Acta 2003;329:9-22
    • (2003) Clin Chim Acta , vol.329 , pp. 9-22
    • Beguin, Y.1
  • 24
    • 0018131817 scopus 로고
    • Iron absorption and serum ferritin in chronic inflammatory bowel disease
    • Bartels U, Pedersen NS, Jarnum S. Iron absorption and serum ferritin in chronic inflammatory bowel disease. Scand J Gastroenterol 1978;13:649-56
    • (1978) Scand J Gastroenterol , vol.13 , pp. 649-656
    • Bartels, U.1    Pedersen, N.S.2    Jarnum, S.3
  • 25
    • 3242698640 scopus 로고    scopus 로고
    • Iron, anemia, and inflammatory bowel diseases
    • Gasche C, Lomer MC, Cavill I, Weiss G. Iron, anemia, and inflammatory bowel diseases. Gut 2004;53:1190-7
    • (2004) Gut , vol.53 , pp. 1190-1197
    • Gasche, C.1    Lomer, M.C.2    Cavill, I.3    Weiss, G.4
  • 26
    • 0020058810 scopus 로고
    • Failure of serum ferritin levels to predict bone-marrow iron content after intravenous iron-dextran therapy
    • Ali M, Rigolosi R, Fayemi AO, Braun EV, Frascino J, Singer R. Failure of serum ferritin levels to predict bone-marrow iron content after intravenous iron-dextran therapy. Lancet 1982;1:652-5
    • (1982) Lancet , vol.1 , pp. 652-655
    • Ali, M.1    Rigolosi, R.2    Fayemi, A.O.3    Braun, E.V.4    Frascino, J.5    Singer, R.6
  • 27
    • 0030581590 scopus 로고    scopus 로고
    • Randomised study of cognitive effects of iron supplementation in non-anemic iron-deficient adolescent girls
    • Bruner AB, Joffe A, Duggan AK, Casella JF, Brandt J. Randomised study of cognitive effects of iron supplementation in non-anemic iron-deficient adolescent girls. Lancet 1996;348:992-6
    • (1996) Lancet , vol.348 , pp. 992-996
    • Bruner, A.B.1    Joffe, A.2    Duggan, A.K.3    Casella, J.F.4    Brandt, J.5
  • 29
    • 80053118808 scopus 로고    scopus 로고
    • Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration
    • Krayenbuehl PA, Battegay E, Breymann C, Furrer J, Schulthess G. Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration. Blood 2011;118:3222-7
    • (2011) Blood , vol.118 , pp. 3222-3227
    • Krayenbuehl, P.A.1    Battegay, E.2    Breymann, C.3    Furrer, J.4    Schulthess, G.5
  • 30
    • 80054040457 scopus 로고    scopus 로고
    • Improved differential diagnosis of anemia of chronic disease and iron deficiency anemia: a prospective multicenter evaluation of soluble transferrin receptor and the sTfR/log ferritin index
    • Skikne BS, Punnonen K, Caldron PH, et al. Improved differential diagnosis of anemia of chronic disease and iron deficiency anemia: a prospective multicenter evaluation of soluble transferrin receptor and the sTfR/log ferritin index. Am J Hematol 2011;86:923-7
    • (2011) Am J Hematol , vol.86 , pp. 923-927
    • Skikne, B.S.1    Punnonen, K.2    Caldron, P.H.3
  • 31
    • 80855123471 scopus 로고    scopus 로고
    • Soluble transferrin receptor-ferritin index is the most efficient marker for the diagnosis of iron deficiency anemia in patients with IBD
    • Oustamanolakis P, Koutroubakis IE. Soluble transferrin receptor-ferritin index is the most efficient marker for the diagnosis of iron deficiency anemia in patients with IBD. Inflamm Bowel Dis 2011;17:E158-9
    • (2011) Inflamm Bowel Dis , vol.17 , pp. E158-E159
    • Oustamanolakis, P.1    Koutroubakis, I.E.2
  • 32
    • 84868130107 scopus 로고    scopus 로고
    • Soluble transferrin receptor [sTfR] and sTfR/log ferritin index for the diagnosis of iron-deficiency anemia: a meta-analysis
    • Infusino I, Braga F, Dolci A, Panteghini M. Soluble transferrin receptor [sTfR] and sTfR/log ferritin index for the diagnosis of iron-deficiency anemia: a meta-analysis. Am J Clin Pathol 2012;138:642-9
    • (2012) Am J Clin Pathol , vol.138 , pp. 642-649
    • Infusino, I.1    Braga, F.2    Dolci, A.3    Panteghini, M.4
  • 33
    • 33751579324 scopus 로고    scopus 로고
    • Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation
    • Semrin G, Fishman DS, Bousvaros A, et al. Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation. Inflamm Bowel Dis 2006;12:1101-6
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 1101-1106
    • Semrin, G.1    Fishman, D.S.2    Bousvaros, A.3
  • 34
    • 84872951347 scopus 로고    scopus 로고
    • Hepcidin levels predict nonresponsiveness to oral iron therapy in patients with iron deficiency anemia
    • Bregman DB, Morris D, Koch TA, He A, Goodnough LT. Hepcidin levels predict nonresponsiveness to oral iron therapy in patients with iron deficiency anemia. Am J Hematol 2013;88:97-101
    • (2013) Am J Hematol , vol.88 , pp. 97-101
    • Bregman, D.B.1    Morris, D.2    Koch, T.A.3    He, A.4    Goodnough, L.T.5
  • 35
    • 33645030120 scopus 로고    scopus 로고
    • Effects of changes in hemoglobin level on quality of life and cognitive function in inflammatory bowel disease patients
    • Wells CW, Lewis S, Barton JR, Corbett S. Effects of changes in hemoglobin level on quality of life and cognitive function in inflammatory bowel disease patients. Inflamm Bowel Dis 2006;12:123-30
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 123-130
    • Wells, C.W.1    Lewis, S.2    Barton, J.R.3    Corbett, S.4
  • 36
    • 80052108611 scopus 로고    scopus 로고
    • FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease
    • Evstatiev R, Marteau P, Iqbal T, et al. FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease. Gastroenterology 2011;141:846-53, e841-42
    • (2011) Gastroenterology , vol.141
    • Evstatiev, R.1    Marteau, P.2    Iqbal, T.3
  • 37
    • 72449156527 scopus 로고    scopus 로고
    • Ferric carboxymaltose in patients with heart failure and iron deficiency
    • Anker SD, Comin Colet J, Filippatos G, et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med 2009;361:2436-48
    • (2009) N Engl J Med , vol.361 , pp. 2436-2448
    • Anker, S.D.1    Comin Colet, J.2    Filippatos, G.3
  • 38
    • 84899667132 scopus 로고    scopus 로고
    • Evaluation of a single dose of ferric carboxymaltose in fatigued, iron-deficient women-PREFER, a randomized, placebo-controlled study
    • Favrat B, Balck K, Breymann C, et al. Evaluation of a single dose of ferric carboxymaltose in fatigued, iron-deficient women-PREFER, a randomized, placebo-controlled study. PLoS One 2014;9:e94217
    • (2014) PLoS One , vol.9
    • Favrat, B.1    Balck, K.2    Breymann, C.3
  • 39
    • 0034886891 scopus 로고    scopus 로고
    • Prediction of response to iron sucrose in inflammatory bowel disease-associated anemia
    • Gasche C, Waldhoer T, Feichtenschlager T, et al. Prediction of response to iron sucrose in inflammatory bowel disease-associated anemia. Am J Gastroenterol 2001;96:2382-7
    • (2001) Am J Gastroenterol , vol.96 , pp. 2382-2387
    • Gasche, C.1    Waldhoer, T.2    Feichtenschlager, T.3
  • 40
    • 84874568807 scopus 로고    scopus 로고
    • Ferric carboxymaltose prevents recurrence of anemia in patients with inflammatory bowel disease
    • Evstatiev R, Alexeeva O, Bokemeyer B, et al. Ferric carboxymaltose prevents recurrence of anemia in patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 2013;11:269-77
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 269-277
    • Evstatiev, R.1    Alexeeva, O.2    Bokemeyer, B.3
  • 41
    • 43549093318 scopus 로고    scopus 로고
    • A novel intravenous iron formulation for treatment of anemia in inflammatory bowel disease: the ferric carboxymaltose [FERINJECT] randomized controlled trial
    • Kulnigg S, Stoinov S, Simanenkov V, et al. A novel intravenous iron formulation for treatment of anemia in inflammatory bowel disease: the ferric carboxymaltose [FERINJECT] randomized controlled trial. Am J Gastroenterol 2008;103:1182-92
    • (2008) Am J Gastroenterol , vol.103 , pp. 1182-1192
    • Kulnigg, S.1    Stoinov, S.2    Simanenkov, V.3
  • 42
    • 84894054748 scopus 로고    scopus 로고
    • A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia
    • Onken JE, Bregman DB, Harrington RA, et al. A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia. Transfusion 2014;54:306-15
    • (2014) Transfusion , vol.54 , pp. 306-315
    • Onken, J.E.1    Bregman, D.B.2    Harrington, R.A.3
  • 43
    • 65949107825 scopus 로고    scopus 로고
    • Ferric carboxymaltose: a review of its use in iron-deficiency anemia
    • Lyseng-Williamson KA, Keating GM. Ferric carboxymaltose: a review of its use in iron-deficiency anemia. Drugs 2009;69:739-56
    • (2009) Drugs , vol.69 , pp. 739-756
    • Lyseng-Williamson, K.A.1    Keating, G.M.2
  • 44
    • 0026679838 scopus 로고
    • Structure/histotoxicity relationship of parenteral iron preparations
    • Geisser P, Baer M, Schaub E. Structure/histotoxicity relationship of parenteral iron preparations. Arzneimittelforschung 1992;42:1439-52
    • (1992) Arzneimittelforschung , vol.42 , pp. 1439-1452
    • Geisser, P.1    Baer, M.2    Schaub, E.3
  • 45
    • 0030900144 scopus 로고    scopus 로고
    • Intravenous iron and erythropoietin for anemia associated with Crohn disease. A randomized, controlled trial
    • Gasche C, Dejaco C, Waldhoer T, et al. Intravenous iron and erythropoietin for anemia associated with Crohn disease. A randomized, controlled trial. Ann Intern Med 1997;126:782-7
    • (1997) Ann Intern Med , vol.126 , pp. 782-787
    • Gasche, C.1    Dejaco, C.2    Waldhoer, T.3
  • 46
    • 0032900099 scopus 로고    scopus 로고
    • Sequential treatment of anemia in ulcerative colitis with intravenous iron and erythropoietin
    • Gasche C, Dejaco C, Reinisch W, et al. Sequential treatment of anemia in ulcerative colitis with intravenous iron and erythropoietin. Digestion 1999;60:262-7
    • (1999) Digestion , vol.60 , pp. 262-267
    • Gasche, C.1    Dejaco, C.2    Reinisch, W.3
  • 47
    • 33644653558 scopus 로고    scopus 로고
    • Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease-a randomized, controlled, open-label, multicenter study
    • Schroder O, Mickisch O, Seidler U, et al. Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease-a randomized, controlled, open-label, multicenter study. Am J Gastroenterol 2005;100:2503-9
    • (2005) Am J Gastroenterol , vol.100 , pp. 2503-2509
    • Schroder, O.1    Mickisch, O.2    Seidler, U.3
  • 48
    • 4444247093 scopus 로고    scopus 로고
    • A study for the evaluation of safety and tolerability of intravenous high-dose iron sucrose in patients with iron deficiency anemia due to gastrointestinal bleeding
    • Schroder O, Schrott M, Blumenstein I, Jahnel J, Dignass AU, Stein J. A study for the evaluation of safety and tolerability of intravenous high-dose iron sucrose in patients with iron deficiency anemia due to gastrointestinal bleeding. Z Gastroenterol 2004;42:663-7
    • (2004) Z Gastroenterol , vol.42 , pp. 663-667
    • Schroder, O.1    Schrott, M.2    Blumenstein, I.3    Jahnel, J.4    Dignass, A.U.5    Stein, J.6
  • 49
    • 70350648478 scopus 로고    scopus 로고
    • Intravenous iron sucrose is superior to oral iron sulphate for correcting anemia and restoring iron stores in IBD patients: a randomized, controlled, evaluator-blind, multicentre study
    • Lindgren S, Wikman O, Befrits R, et al. Intravenous iron sucrose is superior to oral iron sulphate for correcting anemia and restoring iron stores in IBD patients: a randomized, controlled, evaluator-blind, multicentre study. Scand J Gastroenterol. 2009;44:838-45
    • (2009) Scand J Gastroenterol , vol.44 , pp. 838-845
    • Lindgren, S.1    Wikman, O.2    Befrits, R.3
  • 50
    • 24744435535 scopus 로고    scopus 로고
    • Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease
    • Erichsen K, Ulvik RJ, Nysaeter G, et al. Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease. ScandJGastroenterol 2005;40:1058-65
    • (2005) ScandJGastroenterol , vol.40 , pp. 1058-1065
    • Erichsen, K.1    Ulvik, R.J.2    Nysaeter, G.3
  • 51
    • 33645103364 scopus 로고    scopus 로고
    • Effectiveness of darbepoetin-alfa in combination with intravenous iron sucrose in patients with inflammatory bowel disease and refractory anemia: a pilot study
    • Koutroubakis IE, Karmiris K, Makreas S, Xidakis C, Niniraki M, Kouroumalis EA. Effectiveness of darbepoetin-alfa in combination with intravenous iron sucrose in patients with inflammatory bowel disease and refractory anemia: a pilot study. Eur J Gastroenterol Hepatol 2006;18:421-5
    • (2006) Eur J Gastroenterol Hepatol , vol.18 , pp. 421-425
    • Koutroubakis, I.E.1    Karmiris, K.2    Makreas, S.3    Xidakis, C.4    Niniraki, M.5    Kouroumalis, E.A.6
  • 52
    • 84884551031 scopus 로고    scopus 로고
    • Iron deficiency generates secondary thrombocytosis and platelet activation in IBD: the randomized, controlled ThromboVIT trial
    • Kulnigg-Dabsch S, Schmid W, Howaldt S, et al. Iron deficiency generates secondary thrombocytosis and platelet activation in IBD: the randomized, controlled ThromboVIT trial. Inflamm Bowel Dis 2013;19:1609-16
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1609-1616
    • Kulnigg-Dabsch, S.1    Schmid, W.2    Howaldt, S.3
  • 53
    • 83155188539 scopus 로고    scopus 로고
    • Ferumoxytol infusion in pediatric patients with gastrointestinal disorders: first case series
    • Hassan N, Cahill J, Rajasekaran S, Kovey K. Ferumoxytol infusion in pediatric patients with gastrointestinal disorders: first case series. Ann Pharmacother 2011;45:e63
    • (2011) Ann Pharmacother , vol.45
    • Hassan, N.1    Cahill, J.2    Rajasekaran, S.3    Kovey, K.4
  • 54
    • 85019889996 scopus 로고    scopus 로고
    • Evaluation of ferumoxytol treatment for iron deficiency anemia in patients with gastrointestinal disorders who have a history of unsatisfactory oral iron therapy: results of a Phase III, randomized, placebo-controlled trial
    • Ford D, Cohen M, Strauss W, et al. Evaluation of ferumoxytol treatment for iron deficiency anemia in patients with gastrointestinal disorders who have a history of unsatisfactory oral iron therapy: results of a Phase III, randomized, placebo-controlled trial. Gastroenterology 2013;144:S754
    • (2013) Gastroenterology , vol.144
    • Ford, D.1    Cohen, M.2    Strauss, W.3
  • 55
    • 77954427833 scopus 로고    scopus 로고
    • Safety and efficacy of total-dose infusion of low molecular weight iron dextran for iron deficiency anemia in patients with inflammatory bowel disease
    • Koutroubakis IE, Oustamanolakis P, Karakoidas C, Mantzaris GJ, Kouroumalis EA. Safety and efficacy of total-dose infusion of low molecular weight iron dextran for iron deficiency anemia in patients with inflammatory bowel disease. Dig Dis Sci 2010;55:2327-31
    • (2010) Dig Dis Sci , vol.55 , pp. 2327-2331
    • Koutroubakis, I.E.1    Oustamanolakis, P.2    Karakoidas, C.3    Mantzaris, G.J.4    Kouroumalis, E.A.5
  • 56
    • 80053647829 scopus 로고    scopus 로고
    • Efficacy and tolerability of intravenous iron dextran and oral iron in inflammatory bowel disease: a case-matched study in clinical practice
    • Khalil A, Goodhand JR, Wahed M, Yeung J, Ali FR, Rampton DS. Efficacy and tolerability of intravenous iron dextran and oral iron in inflammatory bowel disease: a case-matched study in clinical practice. Eur J Gastroenterol Hepatol 2011;23:1029-35
    • (2011) Eur J Gastroenterol Hepatol , vol.23 , pp. 1029-1035
    • Khalil, A.1    Goodhand, J.R.2    Wahed, M.3    Yeung, J.4    Ali, F.R.5    Rampton, D.S.6
  • 57
    • 33646265025 scopus 로고    scopus 로고
    • Iron and the anemia of chronic disease: a review and strategic recommendations
    • Cavill I, Auerbach M, Bailie GR, et al. Iron and the anemia of chronic disease: a review and strategic recommendations. Curr Med Res Opin 2006;22:731-7
    • (2006) Curr Med Res Opin , vol.22 , pp. 731-737
    • Cavill, I.1    Auerbach, M.2    Bailie, G.R.3
  • 58
    • 17944391767 scopus 로고
    • [Intravenous iron-dextran: therapeutic and experimental possibilities]
    • Ganzoni AM. [Intravenous iron-dextran: therapeutic and experimental possibilities]. Schweiz Med Wochenschr 1970;100:301-3
    • (1970) Schweiz Med Wochenschr , vol.100 , pp. 301-303
    • Ganzoni, A.M.1
  • 59
    • 84889690772 scopus 로고    scopus 로고
    • A randomized, open-label, noninferiority study of intravenous iron isomaltoside 1, 000 [Monofer] compared with oral iron for treatment of anemia in IBD [PROCEED]
    • Reinisch W, Staun M, Tandon RK, et al. A randomized, open-label, noninferiority study of intravenous iron isomaltoside 1, 000 [Monofer] compared with oral iron for treatment of anemia in IBD [PROCEED]. Am J Gastroenterol 2013;108:1877-88
    • (2013) Am J Gastroenterol , vol.108 , pp. 1877-1888
    • Reinisch, W.1    Staun, M.2    Tandon, R.K.3
  • 60
    • 0003965195 scopus 로고
    • Geneva: World Health Organization
    • World Health Organization. Nutritional Anemias. Geneva: World Health Organization; 1968
    • (1968) Nutritional Anemias
  • 61
    • 84858075234 scopus 로고    scopus 로고
    • Iron replacement therapy in inflammatory bowel disease patients with iron deficiency anemia: a systematic review and meta-analysis
    • Lee TW, Kolber MR, Fedorak RN, van Zanten SV. Iron replacement therapy in inflammatory bowel disease patients with iron deficiency anemia: a systematic review and meta-analysis. J Crohns Colitis 2012;6:267-75
    • (2012) J Crohns Colitis , vol.6 , pp. 267-275
    • Lee, T.W.1    Kolber, M.R.2    Fedorak, R.N.3    van Zanten, S.V.4
  • 62
    • 28844433694 scopus 로고    scopus 로고
    • Efficacy and tolerability of oral iron therapy in inflammatory bowel disease: a prospective, comparative trial
    • De Silva AD, Tsironi E, Feakins RM, Rampton DS. Efficacy and tolerability of oral iron therapy in inflammatory bowel disease: a prospective, comparative trial. Aliment Pharmacol Ther 2005;22:1097-105
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 1097-1105
    • De Silva, A.D.1    Tsironi, E.2    Feakins, R.M.3    Rampton, D.S.4
  • 63
    • 33748262238 scopus 로고    scopus 로고
    • High-iron diet: foe or feat in ulcerative colitis and ulcerative colitis-associated carcinogenesis
    • Seril DN, Liao J, West AB, Yang GY. High-iron diet: foe or feat in ulcerative colitis and ulcerative colitis-associated carcinogenesis. JClin, Gastroenterol 2006;40:391-7
    • (2006) JClin, Gastroenterol , vol.40 , pp. 391-397
    • Seril, D.N.1    Liao, J.2    West, A.B.3    Yang, G.Y.4
  • 64
    • 0036270885 scopus 로고    scopus 로고
    • Dietary iron supplementation enhances DSS-induced colitis and associated colorectal carcinoma development in mice
    • Seril DN, Liao J, Ho KL, Warsi A, Yang CS, Yang GY. Dietary iron supplementation enhances DSS-induced colitis and associated colorectal carcinoma development in mice. Dig Dis Sci 2002;47:1266-78
    • (2002) Dig Dis Sci , vol.47 , pp. 1266-1278
    • Seril, D.N.1    Liao, J.2    Ho, K.L.3    Warsi, A.4    Yang, C.S.5    Yang, G.Y.6
  • 66
    • 17644422778 scopus 로고    scopus 로고
    • Systemic iron supplementation replenishes iron stores without enhancing colon carcinogenesis in murine models of ulcerative colitis: comparison with iron-enriched diet
    • Seril DN, Liao J, Yang CS, Yang GY. Systemic iron supplementation replenishes iron stores without enhancing colon carcinogenesis in murine models of ulcerative colitis: comparison with iron-enriched diet. Dig Dis Sci 2005;50:696-707
    • (2005) Dig Dis Sci , vol.50 , pp. 696-707
    • Seril, D.N.1    Liao, J.2    Yang, C.S.3    Yang, G.Y.4
  • 67
    • 79851513757 scopus 로고    scopus 로고
    • Depletion of luminal iron alters the gut microbiota and prevents Crohn's disease-like ileitis
    • Werner T, Wagner SJ, Martinez I, et al. Depletion of luminal iron alters the gut microbiota and prevents Crohn's disease-like ileitis. Gut 2011;60:325-33
    • (2011) Gut , vol.60 , pp. 325-333
    • Werner, T.1    Wagner, S.J.2    Martinez, I.3
  • 68
    • 78651316655 scopus 로고    scopus 로고
    • The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'Ivoire
    • Zimmermann MB, Chassard C, Rohner F, et al. The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'Ivoire. Am J Clin Nutr 2010;92:1406-15
    • (2010) Am J Clin Nutr , vol.92 , pp. 1406-1415
    • Zimmermann, M.B.1    Chassard, C.2    Rohner, F.3
  • 69
    • 85019904594 scopus 로고    scopus 로고
    • Ferric Maltol Is Effective in Correcting Iron Deficiency Anemia in Patients with Inflammatory Bowel Disease: results from a Phase-3 Clinical Trial Program
    • (Epub ahead of print)
    • Gasche C, Ahmad T, Tulassay Z, et al. Ferric Maltol Is Effective in Correcting Iron Deficiency Anemia in Patients with Inflammatory Bowel Disease: results from a Phase-3 Clinical Trial Program. Inflamm Bowel Dis (Epub ahead of print)
    • Inflamm Bowel Dis
    • Gasche, C.1    Ahmad, T.2    Tulassay, Z.3
  • 70
    • 0028049495 scopus 로고
    • Regulators of iron balance in humans
    • Finch C. Regulators of iron balance in humans. Blood 1994;84:1697-702
    • (1994) Blood , vol.84 , pp. 1697-1702
    • Finch, C.1
  • 71
    • 84860574815 scopus 로고    scopus 로고
    • Iron sensing and signalling
    • Evstatiev R, Gasche C. Iron sensing and signalling. Gut 2012;61:933-52
    • (2012) Gut , vol.61 , pp. 933-952
    • Evstatiev, R.1    Gasche, C.2
  • 72
    • 25444494196 scopus 로고    scopus 로고
    • Are we giving too much iron?. Low-dose iron therapy is effective in octogenarians
    • Rimon E, Kagansky N, Kagansky M, et al. Are we giving too much iron? Low-dose iron therapy is effective in octogenarians. Am J Med. 2005 118:1142-7
    • (2005) Am J Med , vol.118 , pp. 1142-1147
    • Rimon, E.1    Kagansky, N.2    Kagansky, M.3
  • 73
    • 0038168717 scopus 로고    scopus 로고
    • Efficacy and tolerability of low-dose iron supplements during pregnancy: a randomized controlled trial
    • Makrides M, Crowther CA, Gibson RA, Gibson RS, Skeaff CM. Efficacy and tolerability of low-dose iron supplements during pregnancy: a randomized controlled trial. Am J Clin Nutr 2003;78:145-53
    • (2003) Am J Clin Nutr , vol.78 , pp. 145-153
    • Makrides, M.1    Crowther, C.A.2    Gibson, R.A.3    Gibson, R.S.4    Skeaff, C.M.5
  • 74
    • 66949124302 scopus 로고    scopus 로고
    • Rapid recurrence of IBD-associated anemia and iron deficiency after intravenous iron sucrose and erythropoietin treatment
    • Kulnigg S, Teischinger L, Dejaco C, Waldhor T, Gasche C. Rapid recurrence of IBD-associated anemia and iron deficiency after intravenous iron sucrose and erythropoietin treatment. Am J Gastroenterol 2009;104:1460-7
    • (2009) Am J Gastroenterol , vol.104 , pp. 1460-1467
    • Kulnigg, S.1    Teischinger, L.2    Dejaco, C.3    Waldhor, T.4    Gasche, C.5
  • 75
    • 0034887025 scopus 로고    scopus 로고
    • Anemia in patients with chronic inflammatory bowel disease
    • Cronin CC, Shanahan F. Anemia in patients with chronic inflammatory bowel disease. Am J Gastroenterol 2001;96:2296-8
    • (2001) Am J Gastroenterol , vol.96 , pp. 2296-2298
    • Cronin, C.C.1    Shanahan, F.2
  • 77
    • 34848873156 scopus 로고    scopus 로고
    • Stimulating erythropoiesis in inflammatory bowel disease associated anemia
    • Tsiolakidou G, Koutroubakis IE. Stimulating erythropoiesis in inflammatory bowel disease associated anemia. World J Gastroenterol 2007;13:4798-806
    • (2007) World J Gastroenterol , vol.13 , pp. 4798-4806
    • Tsiolakidou, G.1    Koutroubakis, I.E.2
  • 79
    • 73949096779 scopus 로고    scopus 로고
    • Crohn's disease is associated with restless legs syndrome
    • Weinstock LB, Bosworth BP, Scherl EJ, et al. Crohn's disease is associated with restless legs syndrome. Inflamm Bowel Dis 2010;16:275-9
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 275-279
    • Weinstock, L.B.1    Bosworth, B.P.2    Scherl, E.J.3
  • 80
    • 1642393242 scopus 로고    scopus 로고
    • Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women
    • Brownlie Tt, Utermohlen V, Hinton PS, Haas JD. Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women. Am J Clin Nutr 2004;79:437-43
    • (2004) Am J Clin Nutr , vol.79 , pp. 437-443
    • Brownlie, T.1    Utermohlen, V.2    Hinton, P.S.3    Haas, J.D.4
  • 81
    • 0037304555 scopus 로고    scopus 로고
    • Iron supplementation improves progressive fatigue resistance during dynamic knee extensor exercise in iron-depleted, nonanemic women
    • Brutsaert TD, Hernandez-Cordero S, Rivera J, Viola T, Hughes G, Haas JD. Iron supplementation improves progressive fatigue resistance during dynamic knee extensor exercise in iron-depleted, nonanemic women. Am J Clin Nutr 2003;77:441-8
    • (2003) Am J Clin Nutr , vol.77 , pp. 441-448
    • Brutsaert, T.D.1    Hernandez-Cordero, S.2    Rivera, J.3    Viola, T.4    Hughes, G.5    Haas, J.D.6
  • 82
    • 33845514377 scopus 로고    scopus 로고
    • Iron supplementation maintains ventilatory threshold and improves energetic efficiency in iron-deficient nonanemic athletes
    • Hinton PS, Sinclair LM. Iron supplementation maintains ventilatory threshold and improves energetic efficiency in iron-deficient nonanemic athletes. Eur J Clin Nutr 2007;61:30-9
    • (2007) Eur J Clin Nutr , vol.61 , pp. 30-39
    • Hinton, P.S.1    Sinclair, L.M.2
  • 83
    • 0037901018 scopus 로고    scopus 로고
    • Iron supplementation for unexplained fatigue in non-anemic women: double blind randomised placebo controlled trial
    • Verdon F, Burnand B, Stubi CL, et al. Iron supplementation for unexplained fatigue in non-anemic women: double blind randomised placebo controlled trial. BMJ 2003;326:1124
    • (2003) BMJ , vol.326 , pp. 1124
    • Verdon, F.1    Burnand, B.2    Stubi, C.L.3
  • 84
    • 33750213273 scopus 로고    scopus 로고
    • Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 years
    • Lozoff B, Jimenez E, Smith JB. Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 years. Arch Pediatr Adolesc Med 2006;160:1108-13
    • (2006) Arch Pediatr Adolesc Med , vol.160 , pp. 1108-1113
    • Lozoff, B.1    Jimenez, E.2    Smith, J.B.3
  • 86
    • 84871070051 scopus 로고    scopus 로고
    • Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010
    • Salomon JA, Vos T, Hogan DR, et al. Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010. Lancet 2012;380:2129-43
    • (2012) Lancet , vol.380 , pp. 2129-2143
    • Salomon, J.A.1    Vos, T.2    Hogan, D.R.3
  • 87
    • 76549117147 scopus 로고    scopus 로고
    • Pathogenesis and treatment of anemia in inflammatory bowel disease
    • Weiss G, Gasche C. Pathogenesis and treatment of anemia in inflammatory bowel disease. Haematologica 2010;95:175-8
    • (2010) Haematologica , vol.95 , pp. 175-178
    • Weiss, G.1    Gasche, C.2
  • 88
    • 67650121081 scopus 로고    scopus 로고
    • Autoimmune hemolytic anemia and ophthalmic artery thrombosis preceding the intestinal manifestations of Crohn's disease
    • Tsiopoulos FD, Manolakis AC, Kapsoritakis AN, Psychos AK, Potamianos SP. Autoimmune hemolytic anemia and ophthalmic artery thrombosis preceding the intestinal manifestations of Crohn's disease. Inflamm Bowel Dis 2009;15:487-8
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 487-488
    • Tsiopoulos, F.D.1    Manolakis, A.C.2    Kapsoritakis, A.N.3    Psychos, A.K.4    Potamianos, S.P.5
  • 89
    • 70350599920 scopus 로고    scopus 로고
    • Cholestatic hepatitis, acute acalculous cholecystitis, and hemolytic anemia: primary Epstein-Barr virus infection under azathioprine
    • Hagel S, Bruns T, Kantowski M, Fix P, Seidel T, Stallmach A. Cholestatic hepatitis, acute acalculous cholecystitis, and hemolytic anemia: primary Epstein-Barr virus infection under azathioprine. Inflamm Bowel Dis 2009;15:1613-6
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1613-1616
    • Hagel, S.1    Bruns, T.2    Kantowski, M.3    Fix, P.4    Seidel, T.5    Stallmach, A.6
  • 94
    • 77957824717 scopus 로고    scopus 로고
    • A case of ulcerative colitis associated with autoimmune hemolytic anemia successfully treated by autologous hematopoietic stem cell transplantation
    • Yu LZ, Qian S, Hong M, Liu P, Li J. A case of ulcerative colitis associated with autoimmune hemolytic anemia successfully treated by autologous hematopoietic stem cell transplantation. Am J Gastroenterol 2010;105:2302-4
    • (2010) Am J Gastroenterol , vol.105 , pp. 2302-2304
    • Yu, L.Z.1    Qian, S.2    Hong, M.3    Liu, P.4    Li, J.5
  • 96
    • 67349239342 scopus 로고    scopus 로고
    • Autoimmune hemolytic anemia in a young adult with Crohn's disease and primary sclerosing cholangitis: an unusual association
    • Kallel L, Boubaker J, Filali A. Autoimmune hemolytic anemia in a young adult with Crohn's disease and primary sclerosing cholangitis: an unusual association. J Crohns Colitis 2009;3:134-5
    • (2009) J Crohns Colitis , vol.3 , pp. 134-135
    • Kallel, L.1    Boubaker, J.2    Filali, A.3
  • 97
    • 0036193347 scopus 로고    scopus 로고
    • Autoimmune hemolytic anemia associated with Crohn's disease
    • Hochman JA. Autoimmune hemolytic anemia associated with Crohn's disease. Inflamm Bowel Dis 2002;8:98-100
    • (2002) Inflamm Bowel Dis , vol.8 , pp. 98-100
    • Hochman, J.A.1
  • 98
    • 22244462120 scopus 로고    scopus 로고
    • An unusual case of ulcerative colitis with concurrent extraintestinal manifestations of primary sclerosing cholangitis, thromboembolism, hemolytic anemia, and hemochromatosis
    • Wu CH, Wong JM, Hsieh SC, Yu CL. An unusual case of ulcerative colitis with concurrent extraintestinal manifestations of primary sclerosing cholangitis, thromboembolism, hemolytic anemia, and hemochromatosis. J Microbiol Immunol Infect 2005;38:224-9
    • (2005) J Microbiol Immunol Infect , vol.38 , pp. 224-229
    • Wu, C.H.1    Wong, J.M.2    Hsieh, S.C.3    Yu, C.L.4
  • 99
    • 77951972425 scopus 로고    scopus 로고
    • Autoimmune hemolytic anemia associated with ulcerative colitis: the most important step is to induce complete remission
    • author reply 1204
    • Molnar T, Farkas K, Szepes Z, Nagy F, Wittmann T. Autoimmune hemolytic anemia associated with ulcerative colitis: the most important step is to induce complete remission. Am J Gastroenterol 2010;105:1203-4; author reply 1204
    • (2010) Am J Gastroenterol , vol.105 , pp. 1203-1204
    • Molnar, T.1    Farkas, K.2    Szepes, Z.3    Nagy, F.4    Wittmann, T.5
  • 100
    • 70349454135 scopus 로고    scopus 로고
    • Treatment with infliximab plus methotrexate improves anemia in patients with rheumatoid arthritis independent of improvement in other clinical outcome measures-a pooled analysis from three large, multicenter, double-blind, randomized clinical trials
    • Doyle MK, Rahman MU, Han C, et al. Treatment with infliximab plus methotrexate improves anemia in patients with rheumatoid arthritis independent of improvement in other clinical outcome measures-a pooled analysis from three large, multicenter, double-blind, randomized clinical trials. Semin Arthritis Rheum 2009;39:123-31
    • (2009) Semin Arthritis Rheum , vol.39 , pp. 123-131
    • Doyle, M.K.1    Rahman, M.U.2    Han, C.3
  • 101
    • 68149172593 scopus 로고    scopus 로고
    • Improvement in hemoglobin levels in patients with ankylosing spondylitis treated with infliximab
    • Braun J, van der Heijde D, Doyle MK, et al. Improvement in hemoglobin levels in patients with ankylosing spondylitis treated with infliximab. Arthritis Rheum 2009;61:1032-6
    • (2009) Arthritis Rheum , vol.61 , pp. 1032-1036
    • Braun, J.1    van der Heijde, D.2    Doyle, M.K.3
  • 102
    • 76549094518 scopus 로고    scopus 로고
    • Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor-alpha treatment
    • Bergamaschi G, Di Sabatino A, Albertini R, et al. Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor-alpha treatment. Haematologica 2010;95:199-205
    • (2010) Haematologica , vol.95 , pp. 199-205
    • Bergamaschi, G.1    Di Sabatino, A.2    Albertini, R.3
  • 103
    • 37249047451 scopus 로고    scopus 로고
    • Intravenous iron therapy restores functional iron deficiency induced by infliximab
    • Katsanos K, Cavalier E, Ferrante M, et al. Intravenous iron therapy restores functional iron deficiency induced by infliximab. J Crohns Colitis 2007;1:97-105
    • (2007) J Crohns Colitis , vol.1 , pp. 97-105
    • Katsanos, K.1    Cavalier, E.2    Ferrante, M.3
  • 104
    • 13944261259 scopus 로고    scopus 로고
    • Infliximab for the treatment of chronic anemia in Crohn's disease
    • Domenech E, Manosa M, Masnou H, et al. Infliximab for the treatment of chronic anemia in Crohn's disease. Am J Gastroenterol 2005;100:496
    • (2005) Am J Gastroenterol , vol.100 , pp. 496
    • Domenech, E.1    Manosa, M.2    Masnou, H.3
  • 105
    • 0029931837 scopus 로고    scopus 로고
    • Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease
    • Schreiber S, Howaldt S, Schnoor M, et al. Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease. N Engl J Med 1996;334:619-23
    • (1996) N Engl J Med , vol.334 , pp. 619-623
    • Schreiber, S.1    Howaldt, S.2    Schnoor, M.3
  • 106
    • 77955413734 scopus 로고    scopus 로고
    • Serum vitamin B12 and folate status in patients with inflammatory bowel diseases
    • Yakut M, Ustun Y, Kabacam G, Soykan I. Serum vitamin B12 and folate status in patients with inflammatory bowel diseases. Eur J Intern Med 2010;21:320-3
    • (2010) Eur J Intern Med , vol.21 , pp. 320-323
    • Yakut, M.1    Ustun, Y.2    Kabacam, G.3    Soykan, I.4
  • 108
    • 79960876922 scopus 로고    scopus 로고
    • Indicators for assessing folate and vitamin B-12 status and for monitoring the efficacy of intervention strategies
    • Green R. Indicators for assessing folate and vitamin B-12 status and for monitoring the efficacy of intervention strategies. Am J Clin Nutr 2011;94:666S-672S
    • (2011) Am J Clin Nutr , vol.94 , pp. 666S-672S
    • Green, R.1
  • 109
    • 0031774239 scopus 로고    scopus 로고
    • Mesalazine-associated severe aplastic anemia successfully treated with antithymocyte globulin, cyclosporine and granulocyte colony-stimulating factor
    • Otsubo H, Kaito K, Sekita T, Shimada T, Kobayashi M, Hosoya T. Mesalazine-associated severe aplastic anemia successfully treated with antithymocyte globulin, cyclosporine and granulocyte colony-stimulating factor. Int J Hematol 1998;68:445-8
    • (1998) Int J Hematol , vol.68 , pp. 445-448
    • Otsubo, H.1    Kaito, K.2    Sekita, T.3    Shimada, T.4    Kobayashi, M.5    Hosoya, T.6
  • 111
    • 84871730245 scopus 로고    scopus 로고
    • Transfusion strategies for acute upper gastrointestinal bleeding
    • Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013;368:11-21
    • (2013) N Engl J Med , vol.368 , pp. 11-21
    • Villanueva, C.1    Colomo, A.2    Bosch, A.3
  • 112
    • 0343360868 scopus 로고    scopus 로고
    • A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group
    • Hebert PC, Wells G, Blajchman MA, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 199;340:409-17
    • (1999) N Engl J Med , vol.340 , pp. 409-417
    • Hebert, P.C.1    Wells, G.2    Blajchman, M.A.3
  • 113
    • 77957323453 scopus 로고    scopus 로고
    • The health care cost of intravenous iron treatment in IBD patients depends on the economic evaluation perspective
    • Bager P, Dahlerup JF. The health care cost of intravenous iron treatment in IBD patients depends on the economic evaluation perspective. J Crohns Colitis 2010;4:427-430
    • (2010) J Crohns Colitis , vol.4 , pp. 427-430
    • Bager, P.1    Dahlerup, J.F.2
  • 114
    • 70349786607 scopus 로고    scopus 로고
    • Blood transfusion for the treatment of acute anemia in inflammatory bowel disease and other digestive diseases
    • Garcia-Erce JA, Gomollon F, Munoz M. Blood transfusion for the treatment of acute anemia in inflammatory bowel disease and other digestive diseases. World J Gastroenterol 2009;15:4686-94
    • (2009) World J Gastroenterol , vol.15 , pp. 4686-4694
    • Garcia-Erce, J.A.1    Gomollon, F.2    Munoz, M.3
  • 115
    • 33746892274 scopus 로고    scopus 로고
    • Practice guidelines for perioperative blood transfusion and adjuvant therapies: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies
    • American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies
    • American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Practice guidelines for perioperative blood transfusion and adjuvant therapies: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Anesthesiology 2006;105:198-208
    • (2006) Anesthesiology , vol.105 , pp. 198-208
  • 116
    • 77951624081 scopus 로고    scopus 로고
    • Absence of cardiac siderosis despite hepatic iron overload in Italian patients with thalassemia intermedia: an MRI T2* study
    • Roghi A, Cappellini MD, Wood JC, et al. Absence of cardiac siderosis despite hepatic iron overload in Italian patients with thalassemia intermedia: an MRI T2* study. Ann Hematol 2010;89:585-9
    • (2010) Ann Hematol , vol.89 , pp. 585-589
    • Roghi, A.1    Cappellini, M.D.2    Wood, J.C.3
  • 117
    • 0034162598 scopus 로고    scopus 로고
    • Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine
    • Decaux G, Prospert F, Horsmans Y, Desager JP. Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine. J Lab Clin Med 2000;135:256-62
    • (2000) J Lab Clin Med , vol.135 , pp. 256-262
    • Decaux, G.1    Prospert, F.2    Horsmans, Y.3    Desager, J.P.4
  • 119
    • 0036076821 scopus 로고    scopus 로고
    • TPMT in the treatment of Crohn's disease with azathioprine
    • Lennard L. TPMT in the treatment of Crohn's disease with azathioprine. Gut 2002;51:143-6
    • (2002) Gut , vol.51 , pp. 143-146
    • Lennard, L.1
  • 121
    • 7244261983 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase genotype predicts azathioprine-induced myelotoxicity in kidney transplant recipients
    • Formea CM, Myers-Huentelman H, Wu R, et al. Thiopurine S-methyltransferase genotype predicts azathioprine-induced myelotoxicity in kidney transplant recipients. Am J Transplant 2004;4:1810-7
    • (2004) Am J Transplant , vol.4 , pp. 1810-1817
    • Formea, C.M.1    Myers-Huentelman, H.2    Wu, R.3
  • 122
    • 11144312471 scopus 로고    scopus 로고
    • Azathioprineinduced pure red cell aplasia: case report and review
    • Agrawal A, Parrott NR, Riad HN, Augustine T. Azathioprineinduced pure red cell aplasia: case report and review. Transplant Proc 2004;36:2689-91
    • (2004) Transplant Proc , vol.36 , pp. 2689-2691
    • Agrawal, A.1    Parrott, N.R.2    Riad, H.N.3    Augustine, T.4
  • 124
    • 0042830383 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase [TPMT] genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease
    • Gearry RB, Barclay ML, Burt MJ, et al. Thiopurine S-methyltransferase [TPMT] genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2003;18:395-400
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 395-400
    • Gearry, R.B.1    Barclay, M.L.2    Burt, M.J.3
  • 125
    • 0036278519 scopus 로고    scopus 로고
    • The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review
    • Fraser AG, Orchard TR, Jewell DP. The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review. Gut 2002,;50:485-9
    • (2002) Gut , vol.50 , pp. 485-489
    • Fraser, A.G.1    Orchard, T.R.2    Jewell, D.P.3
  • 126
    • 0034093057 scopus 로고    scopus 로고
    • Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy
    • Colombel JF, Ferrari N, Debuysere H, et al. Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy. Gastroenterology 2000;118:1025-30
    • (2000) Gastroenterology , vol.118 , pp. 1025-1030
    • Colombel, J.F.1    Ferrari, N.2    Debuysere, H.3
  • 127
    • 0032212759 scopus 로고    scopus 로고
    • Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine
    • Black AJ, McLeod HL, Capell HA, et al. Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine. Ann Intern Med 1998;129:716-8
    • (1998) Ann Intern Med , vol.129 , pp. 716-718
    • Black, A.J.1    McLeod, H.L.2    Capell, H.A.3
  • 128
    • 0842288110 scopus 로고    scopus 로고
    • Mistaken identity: misclassification of TPMT phenotype following blood transfusion
    • Cheung ST, Allan RN. Mistaken identity: misclassification of TPMT phenotype following blood transfusion. Eur J Gastroenterol Hepatol 2003;15:1245-7
    • (2003) Eur J Gastroenterol Hepatol , vol.15 , pp. 1245-1247
    • Cheung, S.T.1    Allan, R.N.2
  • 129
    • 3242762099 scopus 로고    scopus 로고
    • Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants
    • Schaeffeler E, Fischer C, Brockmeier D, et al. Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants. Pharmacogenetics 2004;14:407-17
    • (2004) Pharmacogenetics , vol.14 , pp. 407-417
    • Schaeffeler, E.1    Fischer, C.2    Brockmeier, D.3
  • 130
    • 33750581390 scopus 로고    scopus 로고
    • Three novel thiopurine S-methyltransferase allelic variants [TPMT*20, *21, *22]-association with decreased enzyme function
    • Schaeffeler E, Eichelbaum M, Reinisch W, Zanger UM, Schwab M. Three novel thiopurine S-methyltransferase allelic variants [TPMT*20, *21, *22]-association with decreased enzyme function. Hum Mutat 2006;27:976
    • (2006) Hum Mutat , vol.27 , pp. 976
    • Schaeffeler, E.1    Eichelbaum, M.2    Reinisch, W.3    Zanger, U.M.4    Schwab, M.5
  • 131
    • 59149103298 scopus 로고    scopus 로고
    • Systematic review: does concurrent therapy with 5-ASA and immunomodulators in inflammatory bowel disease improve outcomes?
    • Andrews JM, Travis SP, Gibson PR, Gasche C. Systematic review: does concurrent therapy with 5-ASA and immunomodulators in inflammatory bowel disease improve outcomes? Aliment Pharmacol Ther 2009;29:459-69
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 459-469
    • Andrews, J.M.1    Travis, S.P.2    Gibson, P.R.3    Gasche, C.4
  • 132
    • 1542515337 scopus 로고    scopus 로고
    • Pharmacogenomics and IBD: TPMT and thiopurines
    • Sandborn WJ. Pharmacogenomics and IBD: TPMT and thiopurines. Inflamm Bowel Dis 2004;10 Suppl 1:S35-;7
    • (2004) Inflamm Bowel Dis , vol.10 , pp. S35-S37
    • Sandborn, W.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.