Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration

Blood

Volumn 118, Issue 12, 2011, Pages 3222-3227

  Krayenbuehl, Pierre Alexandre ^a   Battegay, Edouard ^a   Breymann, Christian ^a   Furrer, Joerg ^a   Schulthess, Georg ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b Department of Anesthesia and Intensive Care Medicine Regional Hospital Maennedorf   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

FERRIC HYDROXIDE; FERRITIN; HEMOGLOBIN; IRON; PLACEBO;

ADULT; APPENDICITIS; ARTICLE; CHILL; CONTROLLED STUDY; DIARRHEA; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DYSESTHESIA; DYSGEUSIA; FATIGUE; FEMALE; FERRITIN BLOOD LEVEL; FOLLOW UP; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; NAUSEA; PREMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THORAX PAIN;

EID: 80053118808     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-04-346304     Document Type: Article

References (27)

1. Bates DW, Schmitt W, Buchwald D, et al. Prevalence of fatigue and chronic fatigue syndrome in a primary care practice. Arch Intern Med. 1993; 153(24):2759-2765. (Pubitemid 24005651)
2. Cathébras PJ, Robbins JM, Kirmayer LJ, Hayton BC. Fatigue in primary care: prevalence, psychiatric comorbidity, illness behavior, and outcome. J Gen Intern Med. 1992;7(3):276-286.
3. Fuhrer R, Wessely S. The epidemiology of fatigue and depression: a French primary-care study. Psychol Med. 1995;25(5):895-905.
4. Kroenke K, Arrington ME, Mangelsdorff AD. The prevalence of symptoms in medical outpatients and the adequacy of therapy. Arch Intern Med. 1990;150(8):1685-1689. (Pubitemid 20240981)
5. Pawlikowska T, Chalder T, Hirsch SR, et al. Population based study of fatigue and psychological distress. BMJ. 1994;308(6931):763-766. (Pubitemid 24087440)
6. Alleyne M, Horne MK, Miller JL. Individualized treatment for iron-deficiency anemia in adults. Am J Med. 2008;121(11):943-948.
7. Galan P, Yoon HC, Preziosi P, et al. Determining factors in the iron status of adult women in the SU.VI.MAX study. Supplementation en VItamines et Mineraux AntioXydants. Eur J Clin Nutr. 1998; 52(6):383-388. (Pubitemid 28284775)
8. Hercberg S, Preziosi P, Galan P. Iron deficiency in Europe. Public Health Nutr. 2001;4(2B):537-545. (Pubitemid 32524575)
9. Morrison JD. Fatigue as a presenting complaint in family practice. J Fam Pract. 1980;10(5):795-801.
10. Ridsdale L, Evans A, Jerrett W, et al. Patients with fatigue in general practice: a prospective study. BMJ. 1993;307(6896):103-106. (Pubitemid 23189573)
11. Beutler E, Larsh S, Gurney C. Iron therapy in chronically fatigued, nonanemic women: a double-blind study. Ann Intern Med. 1960;52:378-394.
12. Patterson AJ, Brown WJ, Roberts DC. Dietary and supplement treatment of iron deficiency results in improvements in general health and fatigue in Australian women of childbearing age. J Am Coll Nutr. 2001;20(4):337-342. (Pubitemid 32744209)
13. Verdon F, Burnand B, Stubi CL, et al. Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial. BMJ. 2003;326(7399):1124-1126. (Pubitemid 36613445)
14. Anker SD, Comin CJ, Filippatos G, et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med. 2009;361(25): 2436-2448.
15. Brownlie T, Utermohlen V, Hinton PS, Giordano C, Haas JD. Marginal iron deficiency without anemia impairs aerobic adaptation among previously untrained women. Am J Clin Nutr. 2002;75(4):734-742. (Pubitemid 34256352)
16. Hinton PS, Giordano C, Brownlie T, Haas JD. Iron supplementation improves endurance after training in iron-depleted, nonanemic women. J Appl Physiol. 2000;88(3):1103-1111. (Pubitemid 30154917)
17. Bruner AB, Joffe A, Duggan AK, Casella JF, Brandt J. Randomised study of cognitive effects of iron supplementation in non-anaemic iron-deficient adolescent girls. Lancet. 1996;348(9033): 992-996. (Pubitemid 26340755)
18. Murray-Kolb LE, Beard JL. Iron treatment normalizes cognitive functioning in young women. Am J Clin Nutr. 2007;85(3):778-787. (Pubitemid 46393510)
19. Cho HJ, Hotopf M, Wessely S. The placebo response in the treatment of chronic fatigue syndrome: a systematic review and meta-analysis. Psychosom Med. 2005;67(2):301-313. (Pubitemid 40410968)
20. Locatelli F, Aljama P, Barany P, et al. Revised European best practice guidelines for the management of anaemia in patients with chronic renal failure. Nephrol Dial Transplant. 2004;19(suppl 2):ii1-ii47.
21. Mendoza TR, Wang XS, Cleeland CS, et al. The rapid assessment of fatigue severity in cancer patients: use of the Brief Fatigue Inventory. Cancer. 1999;85(5):1186-1196. (Pubitemid 29115600)
22. Radbruch L, Sabatowski R, Elsner F, et al. Validation of the German version of the brief fatigue inventory. J Pain Symptom Manage. 2003;25(5):449-458. (Pubitemid 36506674)
23. European Medicines Agency. Guideline on Missing Data in Confirmatory Clinical Trials. London: European Medicines Agency; 2009. Available from: http://www.ema.europa.eu/.
24. World Health Organization, United Nations Children's Fund, United Nations University. Iron Deficiency Anaemia: Assessment, Prevention, and Control. A Guide for Programme Managers. Geneva: World Health Organization; 2010. Available from: http://www.who.int/nutrition/publications/ micronutrients/anaemia-iron- deficiency/en/ida-assessment-prevention-control.pdf.
25. Ackrell BA, Maguire JJ, Dallman PR, Kearney EB. Effect of iron deficiency on succinate- and NADH-ubiquinone oxidoreductases in skeletal muscle mitochondria. J Biol Chem. 1984;259(16):10053-10059. (Pubitemid 14067675)
26. Finch CA, Miller LR, Inamdar AR, et al. Iron deficiency in the rat. Physiological and biochemical studies of muscle dysfunction. J Clin Invest. 1976;58(2):447-453.
27. McLane JA, Fell RD, McKay RH, Winder WW, Brown EB, Holloszy JO. Physiological and biochemical effects of iron deficiency on rat skeletal muscle. Am J Physiol. 1981;241(1):C47-C54. (Pubitemid 11044051)