SIRT3 overexpression attenuates palmitate-induced pancreatic β-cell dysfunction

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Kim, Min ^a   Lee, Ji Seon ^a   Oh, Joo En ^a   Nan, Jinyan ^a   Lee, Hakmo ^a   Jung, Hye Seung ^a   Chung, Sung Soo ^a   Park, Kyong Soo ^a,b  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; FULL LENGTH SIRTUIN 3; GLUCOSE; INSULIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PALMITIC ACID; SIRTUIN 3; TRUNCATED FORM SIRTUIN 3; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; CASPASE 3; PALMITIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATF4 GENE; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FKBP11 GENE; GENE; GENE OVEREXPRESSION; GRP94 GENE; INSULIN RELEASE; LIPOTOXICITY; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET DISEASE; RAT; SIGNAL TRANSDUCTION; VIRAL GENE DELIVERY SYSTEM; ANIMAL; CELL LINE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PROTEIN TRANSPORT; TRANSGENIC MOUSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CASPASE 3; CELL DEATH; CELL LINE; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; PALMITATES; PROTEIN TRANSPORT; RATS; SIRTUIN 3;

EID: 84928599384     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124744     Document Type: Article

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