Comparative phytochemical analysis of Gentiana cruciata L. roots and aerial parts, and their biological activities

Industrial Crops and Products

Volumn 73, Issue , 2015, Pages 49-62

  Mihailović, Vladimir ^a   Mišić, Danijela ^b   Matić, Sanja ^a   Mihailović, Mirjana ^b   Stanić, Snežana ^a   Vrvić, Miroslav M ^c   Katanić, Jelena ^a   Mladenović, Milan ^a   Stanković, Nevena ^a   Boroja, Tatjana ^a   Stanković, Milan S ^a  

^a UNIVERSITY OF KRAGUJEVAC   (Serbia)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Antigenotoxicity; Antioxidant activity; Extract stability; Genotoxicity; Gentiana cruciata L.; In vitro digestion

Indexed keywords

AGENTS; ANTIGENS; ASSAYS; PHENOLS; PLANTS (BOTANY);

ANTI-OXIDANT ACTIVITIES; ANTIGENOTOXICITY; GENOTOXICITIES; GENTIANA CRUCIATA L; IN-VITRO DIGESTIONS;

ANTIOXIDANTS;

GENTIANA CRUCIATA; RATTUS NORVEGICUS;

EID: 84928531344     PISSN: 09266690     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.indcrop.2015.04.013     Document Type: Article

References (76)

1. Aberham A., Pieri A., Croom E., Ellmerer E., Stuppner H. Analysis of iridoids, secoiridoids and xanthones in Centaurium erythraea, Frasera caroliniensis and Gentiana lutea using LC-MS and RP-HPLC. J. Pharm. Biomed. Anal. 2011, 54:517-525.
2. Al-Busafi S., Al-Harthi M., Al-Sabahi B. Isolation of aristolochic acids from Aristolochia bracteolata and studies of their antioxidant activities. SQU J. Sci. 2004, 9:19-23.
3. Al-Rasheed N.M., Al-Rasheed N.M., Faddah L.M., Mohamed A.M., Mohammad R.A., Al-Amin M. Potential impact of silymarin in combination with chlorogenic acid and/or melatonin in combating cardiomyopathy induced by carbon tetrachloride. Saudi J. Biol. Sci. 2014, 21:265-274.
4. Ammar R.B., Sghaier M.B., Boubaker J., Bhouri W., Naffeti A., Skandrani I., Bouhlel I., Kilani S., Ghedira K., Chekir-Ghedira L. Antioxidant activity and inhibition of aflatoxin B1- nifuroxazide-, and sodium azide-induced mutagenicity by extracts from Rhamnus alaternus L. Chem. Biol. Interact. 2008, 174:1-10.
5. Bate-Smith E.C. Astringent tannins of Acer species. Phytochemistry 1977, 16:1421-1426.
6. Bermudez-Soto M.J., Tomas-Barberan F.A., Garcia-Conesa M.T. Stability of polyphenols in chokeberry (Aronia melanocarpa) subjected to in vitro gastric and pancreatic digestion. Food Chem. 2007, 102:865-874.
7. Brighente I.M.C., Dias M., Verdi L.G., Pizzo-latti M.G. Antioxidant activity and total phenolic content of some Brazilian species. Pharm. Biol. 2007, 45:156-161.
8. Carnat A., Fraisse D., Carnat A.P., Felgines C., Chaud D., Lamaison J.L. Influence of drying mode on iridoid bitter constituent levels in gentian root. J. Sci. Food Agric. 2005, 85:598-602.
9. Carocho M., Ferreira I. A review on antioxidants, prooxidants and related controversy natural and synthetic compounds, screening and analysis methodologies and future perspectives. Food Chem. Toxicol. 2013, 51:15-25.
10. Chiang Y.C., Chen C.L., Jeng T.L., Lin T.C., Sung J.M. Bioavailability of cranberry bean hydroalcoholic extract and its inhibitory effect against starch hydrolysis following in vitro gastrointestinal digestion. Food Res. Int. 2014, 64:939-945.
11. Choe E., Min D. Mechanisms of antioxidants in the oxidation of foods. Compr. Rev. Food Sci. Food Saf. 2009, 8:354-358.
12. Collins A.R. Comet assay for DNA damage and repair: principles applications and limitations. Mol. Biotechnol. 2004, 26:249-261.
13. Dević M., Momčilović I., Krstić D., Maksimović V., Konjević R. In vitro multiplication of wollow getian (Gentiana asclepiadea L.) and the production of gentiopicrine and mangiferin. Phyton 2006, 46:45-54.
14. Enari H., Takahashi Y., Kawarasaki M., Tada M., Tatsuta K. Identification of angiotensin I-converting enzyme inhibitory peptides derived from salmon muscle and their antihypertensive effect. Fish. Sci. 2008, 74(4):911-920.
15. European Medicines Agency (EMA) Assessment Report on Gentiana lutea L., Radix. (Doc.Ref. :EMA/HMPC/578322/2008) 2009, Committee on Herbal Medicinal Products, London, UK.
16. Ferreira E.A., Gris E.F., Felipe K.B., Correia J.F.G., Cargnin-Ferreira E., Filho D.W., Pedrosa R.C. Potent hepatoprotective effect in CCl4-induced hepatic injury in mice of phloroacetophenone from Myrcia multiflora. Libyan J. Med. 2010, 5:4891.
17. García-Rodríguez M.C., Carvente-Juárez M.M., Altamirano-Lozano M.A. Antigenotoxic and apoptotic activity of green tea polyphenol extracts on hexavalent chromium-induced DNA damage in peripheral blood of CD-1 mice: analysis with differential acridine orange/ethidium bromide staining. Oxid. Med. Cell Longev. 2013, 9. Article ID 486419. 10.1155/2013/486419.
18. Ghisalberti E.L. Biological and pharmacological activity of naturally occurring iridoids and secoiridoids. Phytomedicine 1998, 5:147-163.
19. Goetz M., Hostettmann K., Jacot-Gullarmod A. C-glucosides flavoniques et xanthoniques de Gentiana cruciate. Phytochemistry 1976, 15:2015.
20. Hartmann A., Speit G. The contribution of cytotoxicity to DNA effects in the single cell gel test (comet assay). Toxicol. Lett. 1997, 90(2-3):183-188.
21. Haslam E. Galloyl esters in the Aceraceae. Phytochemistry 1965, 4:495-498.
22. Hayta S., Gurel A., Akgun I.H., Altan F., Ganzera M., Tanyolac B., Bedir E. Induction of Gentiana cruciata hairy roots and their secondary metabolites. Biologia 2011, 66:618-625.
23. Hayta S., Akgun I.H., Ganzera M., Bedir E., Gurel A. Plant Cell Tissue Organ Cult. 2011, 107:175-180.
24. Heber D. Vegetables, fruits and phytoestrogens in the prevention of diseases. J. Postgrad. Med. 2004, 50:145-149.
25. Hsu C.K., Chiang B.H., Chen Y.S., Yang J.H., Liu C.L. Improving the antioxidant activity of buckwheat (Fagopyrum tataricm Gaertn) sprout with trace element water. Food Chem. 2008, 108:633-641.
26. Iwai S., Karim R., Kitano M., Sukata T., Min W., Morimura K., Wanibuchi H., Seki S., Fukushima S. Role of oxidative DNA damage caused by carbon tetrachloride-induced liver injury - enhancement of MeIQ-induced glutathione S-transferase placental form-positive foci in rats. Cancer Lett. 2002, 179(1):15-24.
27. Kaur P., Walia A., Kumar S., Kaur S. Antigenotoxic activity of polyphenolic rich extracts from Aegle marmelos (L.) correa in human blood lymphocytes and E. coli PQ 37. Rec. Nat. Prod. 2009, 3:68-75.
28. Kittiphattanabawon P., Benjakul S., Visessanguan W., Shahidi F. Gelatin hydrolysate from blacktip shark skin prepared using papaya latex enzyme: antioxidant activity and its potential in model systems. Food Chem. 2012, 135:1118-1126.
29. Kondo Y., Takano F., Hojo H. Suppression of chemically and immunologically induced hepatic injuries by gentiopicroside in mice. Planta Med. 1993, 60:414-416.
30. Kumarasamy Y., Nahar L., Cox P.J., Jaspars M., Sarker S.D. Bioactivity of secoiridoid glycosides from Centaurium erythraea. Phytomedicine 2003, 10:344-347.
31. Kumarasamy Y., Byres M., Cox P.J., Jaspars M., Nahar L., Sarker S.D. Screening seeds of some Scottish plants for free-radical scavenging activity. Phytother. Res. 2007, 21:615-621.
32. Kunchandy E., Rao M.N.A. Oxygen radical scavenging activity of curcumin. Int. J. Pharm. 1990, 58:237-240.
33. López-Alarcón C., Denicola A. Evaluating the antioxidant capacity of natural products: a review on chemical and cellular-based assays. Anal. Chim. Acta 2013, 763:1-10.
34. López-Diazguerrero N.E., Luna-López A., Gutiérrez-Ruiz M.A., Zentella A., Königsberg M. Susceptibility of DNA to oxidative stressors in young and aging mice. Life Sci. 2005, 77:2840-2854.
35. Labrador V., Fernández Freire P., Pérez Martín J.M., Hazen M.J. Cytotoxicity of butylated hydroxyanisole in Vero cells. Cell Biol. Toxicol. 2007, 23:189-199.
36. Lian L.H., Wu Y.L., Wan Y., Li X., Xie W.X., Nan J.X. Anti-apoptotic activity of gentiopicroside in -galactosamine/ipopolysaccharide-induced murine fulminant hepatic failure. Chem. Biol. Interact. 2010, 188:127-133.
37. Makni M., Chtourou Y., Garoui E.M., Boudawara T., Fetoui H. Carbon tetrachloride-induced nephrotoxicity and DNA damage in rats: protective role of vanillin. Hum. Exp. Toxicol. 2012, 31(8):844-852.
38. Manoharan K., Banerjee M.R. β-Carotene reduces sister chromatid exchange induce chemical carcinogens in mouse mammary cells in organ culture. Cell Biol. Int. Rep. 1985, 9:783-789.
39. Mariani E., Polidori M.C., Cherubini A., Mecocci P. Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. J. Chromgr. B 2005, 827:65-75.
40. Matić S., Stanić S., Solujić S., Stanković N., Mladenović M., Mihailović V. Protective role of methanol extracts of Gentiana asclepiadea L. and G. cruciata L. against genotoxic damage induced by ethyl methanesulfonate. Genetika 2013, 45:329-340.
41. Matkowski A., Tasarz P., Szypuła E. Antioxidant activity of herb extracts from five medicinal plants from Lamiaceae, subfamily Lamioideae. J. Med. Plants Res. 2008, 2:321-330.
42. Menković N., Šavikin K., Tasić S., Zbunić G., Stešević S., Milosavljević S., Vincek D. Ethnobotanical study on traditional uses of wild medicinal plants in Prokletije Mountains (Montenegro). J. Ethnopharmacol. 2011, 133:97-107.
43. Mihailović V., Katanić J., Mišić D., Stanković V., Mihailović M., Uskoković A., Arambašić J., Solujić S., Mladenović M., Stanković N. Hepatoprotective effects of secoiridoids-rich extracts from Gentiana cruciata L. against carbon tetrachloride induced liver damage in rats. Food Funct. 2014, 5:1795-1803.
44. Moure A., Cruz J.M., Franco D., Dominguez J.M., Sineiro J., Dominguez H., Núñezb M.J., Parajóa M.J. Natural antioxidants from residual sources. Food Chem. 2001, 72:145-171.
45. Nasri H., Nematbakhsh M., Ghobadi S., Ansari R., Shahinfard N., Rafieian-Kopaei M. Preventive and curative effects of ginger extract against histopathologic changes of gentamicin-induced tubular toxicity in rats. Int. J. Preventive Med. 2013, 4:316-321.
46. Nićiforović N., Abramovič H. Sinapic acid and its derivatives: natural sources and bioactivity. Compr. Rev. Food Sci. Food Saf. 2014, 13:34-51.
47. Niiho Y., Yamazaki T., Nakajima Y., Yamamoto T., Ando H., Hirai Y., Toriizuka K., Ida Y. Gastroprotective effects of bitter principles isolated from Gentian root and Swertia herb on experimentally-induced gastric lesions in rats. J. Nat. Med. 2006, 60:82-88.
48. Niki E. Assessment of antioxidant capacity in vitro and in vivo. Free Radical Biol. Med. 2010, 49:503-515.
49. Oyaizu M. Studies on products of browning reaction prepared from glucoseamine. Jpn. J. Nutr. 1986, 44:307-314.
50. Praveena R., Sadasivam K., Deepha V., Sivakumar R. Antioxidant potential of orientin: a combined experimental and DFT approach. J. Mol. Struct. 2014, 1061:114-123.
51. Prieto P., Pineda M., Aguilar M. Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E1. Anal. Biochem. 1999, 269:337-341.
52. Prieto A.M., Santos A.G., Csipak A.R., Caliri C.M., Silva I.C., Arbex M.A., Silva F.S., Marchi M.R.R., Cavalheiro A.J., Silva D.H.S., Bolzani V.S., Soares C.P. Chemopreventive activity of compounds extracted from Casearia sylvestris (Salicaceae) Sw against DNA damage induced by particulate matter emitted by sugarcane burning near Araraquara. Brazil. Toxicol. Appl. Pharmacol. 2012, 265:368-372.
53. Radović M., Šiler B., Nestorović Živković J., Banjanac T., Živković S., Nikolić M., Soković M., Mišić D. Bioreactor cultivation of Zeltnera beyrichii (Torr. & A. Gray) mans.: a novel source of biologically active compounds. Rec. Nat. Prod. 2013, 7:266-280.
54. Re R., Pellegrini N., Proteggente A., Pannala A., Yang M., RiceEvans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biol. Med. 1999, 26:1231-1237.
55. Rodríguez-Roque M.J., Rojas-Grau M.A., Elez-Martínez P., Martín-Belloso O. Changes in vitamin C, phenolic, and carotenoid profiles throughout in vitro gastrointestinal digestion of a blended fruit juice. J. Agric. Food Chem. 2013, 61:1859-1867.
56. Słoczyńska K., Powroźnik B., Pȩkala E., Waszkielewicz A.M. Antimutagenic compounds and their possible mechanisms of action. J. Appl. Genet. 2014, 55(2):273-285.
57. Sarić M. Medicinal Plants of SR Serbia 1989, SASA, Belgrade, Serbia, (in Serbian).
58. Scalbert A., Monties B., Janin G. Tannins in wood: comparison of different estimation methods. J. Agric. Food Chem. 1989, 37:1324-1329.
59. Sghaier B., Bhouri W., Neffati A., Boubaker J., Skandrani I., Bouhlel I., Kilani S., Chekir-Ghedira L., Ghedira K. Chemical investigation of different crude extracts from Teucrium ramosissimum leaves: correlation with their antigenotoxic and antioxidant properties. Food Chem. Toxicol. 2011, 49:191-201.
60. Shah M.A., Bosco S.J.D., Mir S.A. Plant extracts as natural antioxidants in meat and meat products. Meat Sci. 2014, 98:21-33.
61. Shahidi F., Hong C. Evaluation of malonaldehyde as a marker of oxidative rancidity in meat products. J. Food Biochem. 1991, 15:97-105.
62. Shibano M., Kakutani K., Taniguchi M., Yasuda M., Baba K. Antioxidant constituents in the dayflower (Commelina communis L.) and their α-glucosidase-inhibitory activity. J. Nat. Med. 2008, 62:349-353.
63. Šiler B., Živković S., Banjanac T., Cvetkovicć J., Nestorović Živković J., Ćirić A., Soković M., Mišić D. Centauries as underestimated food additives: antioxidant and antimicrobial potential. Food Chem. 2014, 147:367-376.
64. Singh N.P., Mc Coy M.T., Tic R.R., Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 1988, 175:184-191.
65. Singleton V.L., Orthofer R., Lamuela-Raventos R.M. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent oxidants and antioxidants. Method Enzymol. 1999, 299:152-178.
66. Siu G.M., Draper H.H. A survey of the malonaldehyde content of retail meats and fish. J. Food Sci. 1978, 43:1147-1149.
67. Szücs Z., Danos B., Nyirecty S. Comparative analysis of the underground parts of Gentiana species by HPLC with diode-array and mass spectrometric detection. Chromatographia 2002, 56(Suppl):5. S-19-S-23.
68. Takao T., Watanabe N., Yagi I., Sakata K. A simple screening method for antioxidants and isolation of several antioxidants produced by marine bacteria from fish and shellfish. Biosci. Biotechnol. Biochem. 1994, 58:1780-1783.
69. Vale C.R., Silva C.R., Oliveira C.M.A., Silva A.L., Carvalho S., Chen-Chen L. Assessment of toxic, genotoxic, antigenotoxic, and recombinogenic activities of Hymenaea courbaril (Fabaceae) in Drosophila melanogaster and mice. Genet Mol. Res. 2013, 12(3):2712-2724.
70. Valko M., Leibfritz D., Moncol J., Cronin M.T.D., Mazur M., Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 2007, 39:44-84.
71. Velderrain-Rodriguez G.R., Palafox-Carlos H., Wall-Medrano A., Ayala-Zavala J.F., Chen C.-Y.O., Robles-Sanchez M., Astiazaran-Garcia H., Alvarez-Parrilla E., Gonzalez-Aguilar G.A. Phenolic compounds: their journey after intake. Food Funct. 2014, 5:189-197.
72. Verschaeve L., Van Staden J. Mutagenic and antimutagenic properties of extracts from South African traditional medicinal plants. J. Ethnopharmacol. 2008, 119:575-587.
73. Vulimiri S.V., Pratt M., Kulkarni S., Beedanagari S., Mahadevan B. Reproductive and developmental toxicology: toxic solvents and gases. Reproductive and Developmental Toxicology 2011, 303. Academic Press. R.C. Gupta (Ed.).
74. Waters M.D., Brady A.L., Stack H.F., Brockman H.E. Antimutagenicity profiles for some models compounds. Mutat. Res. 1990, 628:57-85.
75. Wiernsperger N.F. Oxidative stress as a therapeutic target in diabetes: revisiting the controversy. Diabetes Metab. 2003, 29:579-585.
76. Zhao Z.L., Dorje G., Wang Z.T. Identification of medicinal plants used as Tibetan traditional medicine Jie-Ji. J. Ethnopharmacol. 2010, 132:122-126.