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Volumn 5, Issue 1, 2010, Pages

Potent hepatoprotective effect in CCl4-induced hepatic injury in mice of phloroacetophenone from Myrcia multiflora

Author keywords

2 ,4 ,6 trihydroxyacetophenone; Antioxidant; Hepatoprotective; Myrcia multiflora; Silymarin

Indexed keywords


EID: 84867586734     PISSN: 19932820     EISSN: 18196357     Source Type: Journal    
DOI: 10.3402/ljm.v5i0.4891     Document Type: Article
Times cited : (23)

References (50)
  • 2
    • 33646101437 scopus 로고    scopus 로고
    • Cytoprotective effects of carvedilol against oxygen free radical generation in rat liver
    • Ronsein GE, Guidi DB, Benassi JC, Wilhelm Filho D, Pedrosa RC. Cytoprotective effects of carvedilol against oxygen free radical generation in rat liver. Redox Rep. 2005; 10: 131-7.
    • (2005) Redox Rep , vol.10 , pp. 131-137
    • Ronsein, G.E.1    Guidi, D.B.2    Benassi, J.C.3    Wilhelm Filho, D.4    Pedrosa, R.C.5
  • 3
    • 0028876897 scopus 로고
    • Oxygen and xenobiotic reductase activities of cytochrome P450
    • Goeptar AR, Scheerens H, Vermeulen NP. Oxygen and xenobiotic reductase activities of cytochrome P450. Crit Rev Toxicol. 1995; 25: 25-65.
    • (1995) Crit Rev Toxicol , vol.25 , pp. 25-65
    • Goeptar, A.R.1    Scheerens, H.2    Vermeulen, N.P.3
  • 4
    • 0002391242 scopus 로고
    • Free radical damage and lipid peroxidation
    • In: Meeks RG, Harrison SD, Bull RJ, editors, Boca Raton, FL: CRC Press
    • Recknagel RO, Glende EA, Britton RS. Free radical damage and lipid peroxidation. In: Meeks RG, Harrison SD, Bull RJ, editors. Hepatotoxicology. Boca Raton, FL: CRC Press; 1991, pp. 401-36.
    • (1991) Hepatotoxicology , pp. 401-436
    • Recknagel, R.O.1    Glende, E.A.2    Britton, R.S.3
  • 6
  • 8
    • 38549164873 scopus 로고    scopus 로고
    • Hepatoprotective effects of Solanum nigrum Linn extract against CCl4-induced oxidative damage in rats
    • Lin H-M, Tseng H-C, Wang C-J, Lin J-J, Lo C-W, Chou F-P. Hepatoprotective effects of Solanum nigrum Linn extract against CCl4-induced oxidative damage in rats. Chem Biol Interact. 2008; 171: 283-93.
    • (2008) Chem Biol Interact , vol.171 , pp. 283-293
    • Lin, H.-M.1    Tseng, H.-C.2    Wang, C.-J.3    Lin, J.-J.4    Lo, C.-W.5    Chou, F.-P.6
  • 9
    • 0031721802 scopus 로고    scopus 로고
    • Polyphenols: Chemistry, dietary sources, metabolism and nutritional significance
    • Bravo L. Polyphenols: chemistry, dietary sources, metabolism and nutritional significance. Nutr Rev. 1998; 56: 17-33.
    • (1998) Nutr Rev , vol.56 , pp. 17-33
    • Bravo, L.1
  • 10
    • 0031725471 scopus 로고    scopus 로고
    • Antiinflammatory activity of acetophenones from Ophryosporus axilliflorus
    • Favier L, Tonn C, Guerreiro E, Rotelli A, Pelzer L. Antiinflammatory activity of acetophenones from Ophryosporus axilliflorus. Planta Med. 1998; 64: 657-9.
    • (1998) Planta Med , vol.64 , pp. 657-659
    • Favier, L.1    Tonn, C.2    Guerreiro, E.3    Rotelli, A.4    Pelzer, L.5
  • 11
    • 0030639540 scopus 로고    scopus 로고
    • Hydrogen bond formation as basis for radical scavenging activity: A structure-activity study of c-methylated dihydrochalcones from Myrica gale and structurally related acetophenones
    • Mathiesen L, Malterud KE, Sund RB. Hydrogen bond formation as basis for radical scavenging activity: a structure-activity study of c-methylated dihydrochalcones from Myrica gale and structurally related acetophenones. Free Radic Biol Med. 1997; 22: 307-11.
    • (1997) Free Radic Biol Med , vol.22 , pp. 307-311
    • Mathiesen, L.1    Malterud, K.E.2    Sund, R.B.3
  • 12
    • 0013141829 scopus 로고    scopus 로고
    • Phenolic constituents from the aerial parts of Artemisia stolonifera
    • Lee KR, Hong SW, Kwak JH, Pyo S, Jee OP. Phenolic constituents from the aerial parts of Artemisia stolonifera. Arch Pharm Res. 1996; 19: 231-4.
    • (1996) Arch Pharm Res , vol.19 , pp. 231-234
    • Lee, K.R.1    Hong, S.W.2    Kwak, J.H.3    Pyo, S.4    Jee, O.P.5
  • 14
    • 0031937854 scopus 로고    scopus 로고
    • A phloroacetophenone glucoside from Rhododendron ferrugineum
    • Chosson E, Chaboud A, Chulia AJ, Raynaud J. A phloroacetophenone glucoside from Rhododendron ferrugineum. Phytochemistry. 1998; 47: 87-8.
    • (1998) Phytochemistry , vol.47 , pp. 87-88
    • Chosson, E.1    Chaboud, A.2    Chulia, A.J.3    Raynaud, J.4
  • 15
    • 0031887718 scopus 로고    scopus 로고
    • Antidiabetic principles of natural medicines. II. Aldose reductase and alpha-glucosidase inhibitors from Brazilian natural medicine, the leaves of Myrcia multiflora DC. (Myrtaceae): Structures of myrciacitrins I and II and myrciaphenones A and B
    • Yoshikawa M, Shimada H, Nishida N, Li Y, Toguchida I, Yamahara J, Matsuda H. Antidiabetic principles of natural medicines. II. Aldose reductase and alpha-glucosidase inhibitors from Brazilian natural medicine, the leaves of Myrcia multiflora DC. (Myrtaceae): structures of myrciacitrins I and II and myrciaphenones A and B. Chem Pharm Bull. 1998; 46: 113-9.
    • (1998) Chem Pharm Bull , vol.46 , pp. 113-119
    • Yoshikawa, M.1    Shimada, H.2    Nishida, N.3    Li, Y.4    Toguchida, I.5    Yamahara, J.6    Matsuda, H.7
  • 16
    • 0036511915 scopus 로고    scopus 로고
    • Antidiabetic principles of natural medicines. V. Aldose reductase inhibitors from Myrcia multiflora DC. (2): Structures of myrciacitrins III, IV, and V
    • Matsuda H, Nishida N, Yoshikawa M. Antidiabetic principles of natural medicines. V. Aldose reductase inhibitors from Myrcia multiflora DC. (2): structures of myrciacitrins III, IV, and V. Chem Pharm Bull. 2002; 50: 429-31.
    • (2002) Chem Pharm Bull , vol.50 , pp. 429-431
    • Matsuda, H.1    Nishida, N.2    Yoshikawa, M.3
  • 17
    • 33846519345 scopus 로고    scopus 로고
    • Hepatoprotective herbal drug, Silymarin from experimental pharmacology to clinical medicine
    • Pradhan SC, Girish C. Hepatoprotective herbal drug, Silymarin from experimental pharmacology to clinical medicine. Indian J Med Res. 2006; 124: 491-504.
    • (2006) Indian J Med Res , vol.124 , pp. 491-504
    • Pradhan, S.C.1    Girish, C.2
  • 18
    • 0030909065 scopus 로고    scopus 로고
    • A phloracetophenone glucoside with choleretic activity from Curcuma comosa
    • Suksamraran A, Eiamong S, Piyachaturawat P, Byrne LT. A phloracetophenone glucoside with choleretic activity from Curcuma comosa. Phytochemistry. 1997; 45: 103-5.
    • (1997) Phytochemistry , vol.45 , pp. 103-105
    • Suksamraran, A.1    Eiamong, S.2    Piyachaturawat, P.3    Byrne, L.T.4
  • 20
    • 25844500308 scopus 로고    scopus 로고
    • Synthesis and evaluation of antiplatelet activity of trihydroxychalcone derivatives
    • Zhao LM, Jin HS, Sun LP, Piao HR, Quan ZS. Synthesis and evaluation of antiplatelet activity of trihydroxychalcone derivatives. Bioorg Med Chem Lett. 2005; 15: 5027-9.
    • (2005) Bioorg Med Chem Lett , vol.15 , pp. 5027-5029
    • Zhao, L.M.1    Jin, H.S.2    Sun, L.P.3    Piao, H.R.4    Quan, Z.S.5
  • 21
    • 58149364663 scopus 로고
    • Use of free radical method to evaluate antioxidant activity
    • Brand-Williams W, Cuvelier ME, Berset C. Use of free radical method to evaluate antioxidant activity. Leb Wiss Technol. 1995; 28: 25-30.
    • (1995) Leb Wiss Technol , vol.28 , pp. 25-30
    • Brand-Williams, W.1    Cuvelier, M.E.2    Berset, C.3
  • 22
    • 0023864255 scopus 로고
    • Flavonoids are scavengers of superoxide anions
    • Robak J, Gryglewski RJ. Flavonoids are scavengers of superoxide anions. Biochem Pharmacol. 1988; 37: 837-73.
    • (1988) Biochem Pharmacol , vol.37 , pp. 837-873
    • Robak, J.1    Gryglewski, R.J.2
  • 23
    • 0019881197 scopus 로고
    • Formation of thiobarbituric acidreactive substances from deoxyribose in the presence of iron sitsthe role of superoxide and hydroxyl radicals
    • Halliwell B, Gutteridge JMC. Formation of thiobarbituric acidreactive substances from deoxyribose in the presence of iron sitsthe role of superoxide and hydroxyl radicals. FEBS Lett. 1981; 128: 347-52.
    • (1981) FEBS Lett , vol.128 , pp. 347-352
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 24
    • 0004194248 scopus 로고    scopus 로고
    • Protection of multiple antioxidants against heme protein oxidation and lipid peroxidation induced by CBrCl3 in liver, lung, kidney, heart and spleen
    • Chen H, Tappel AL. Protection of multiple antioxidants against heme protein oxidation and lipid peroxidation induced by CBrCl3 in liver, lung, kidney, heart and spleen. J Agric Food Chem. 1996; 44: 854-8.
    • (1996) J Agric Food Chem , vol.44 , pp. 854-858
    • Chen, H.1    Tappel, A.L.2
  • 25
    • 66349129125 scopus 로고
    • A colorimetric method for the determination of serum glutamic oxalacetic and glutamine pyruvic transaminases
    • Reitman S, Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamine pyruvic transaminases. Am J Clin Pathol. 1957; 28: 56-63.
    • (1957) Am J Clin Pathol , vol.28 , pp. 56-63
    • Reitman, S.1    Frankel, S.2
  • 26
    • 0003836992 scopus 로고
    • Methods of enzymatic analysis
    • Bergmeyer HU. Methods of enzymatic analysis. Verl Chem. 1983; 3: 118-25.
    • (1983) Verl Chem , vol.3 , pp. 118-125
    • Bergmeyer, H.U.1
  • 28
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Okawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979; 95: 351-8.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Okawa, H.1    Ohishi, N.2    Yagi, K.3
  • 30
    • 0022272493 scopus 로고
    • Determination of glutathione and glutathione disulfide in biological samples
    • Anderson ME. Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 1985; 113: 548-55.
    • (1985) Methods Enzymol , vol.113 , pp. 548-555
    • Anderson, M.E.1
  • 31
    • 0023919963 scopus 로고
    • A simple technique for quantification of low levels of DNA damage in individual cells
    • Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantification of low levels of DNA damage in individual cells. Exp Cell Res. 1988; 175: 184-91.
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 32
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol. 1984; 105: 121-6.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 33
    • 0015523099 scopus 로고
    • The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase
    • Misra HP, Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem. 1972; 247: 3170-5.
    • (1972) J Biol Chem , vol.247 , pp. 3170-3175
    • Misra, H.P.1    Fridovich, I.2
  • 34
    • 0021288821 scopus 로고
    • Assays of glutathione peroxidase
    • Flohé L, Gunzler WA. Assays of glutathione peroxidase. Methods Enzymol. 1984; 105: 114-21.
    • (1984) Methods Enzymol , vol.105 , pp. 114-121
    • Flohé, L.1    Gunzler, W.A.2
  • 35
    • 71849104860 scopus 로고
    • Protein measurement with Folin phenol reagent
    • Lowry OH, Rosebrough NJ, Farr AL. Protein measurement with Folin phenol reagent. J Biol Chem. 1993; 193: 265-75.
    • (1993) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3
  • 36
    • 0017723981 scopus 로고
    • Liver and skeletal muscle mitochondrial function following burn injury
    • Aprille JR, Hom JA, Rulfs J. Liver and skeletal muscle mitochondrial function following burn injury. J Trauma. 1977; 17: 279-88.
    • (1977) J Trauma , vol.17 , pp. 279-288
    • Aprille, J.R.1    Hom, J.A.2    Rulfs, J.3
  • 37
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Chem. 1976; 72: 248-54.
    • (1976) Anal Chem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 38
    • 56349093051 scopus 로고    scopus 로고
    • Mitochondrial modulation is involved in the hepatoprotection of Limonium sinense extract against liver damage in mice
    • Tang XH, Gao J, Chen J, Xu LZ, Tang YH, Zhao XN, et al. Mitochondrial modulation is involved in the hepatoprotection of Limonium sinense extract against liver damage in mice. J Ethnopharmacol. 2008; 120: 427-31.
    • (2008) J Ethnopharmacol , vol.120 , pp. 427-431
    • Tang, X.H.1    Gao, J.2    Chen, J.3    Xu, L.Z.4    Tang, Y.H.5    Zhao, X.N.6
  • 40
    • 0025074574 scopus 로고
    • Studies on the activity of bepridil as a scavenger of free radicals
    • Constantin M, Bromont C, Fickat R, Massingham R. Studies on the activity of bepridil as a scavenger of free radicals. Biochem Pharmacol. 1990; 40: 1615-22.
    • (1990) Biochem Pharmacol , vol.40 , pp. 1615-1622
    • Constantin, M.1    Bromont, C.2    Fickat, R.3    Massingham, R.4
  • 42
    • 0023219256 scopus 로고
    • The deoxyribose method: A simple "test tube" assay for determination of rate constants for reactions of hydroxyl radicals
    • Halliwell B, Gutteridge JMC, Aruoma OI. The deoxyribose method: a simple "test tube" assay for determination of rate constants for reactions of hydroxyl radicals. Anal Biochem. 1987; 165: 215-9.
    • (1987) Anal Biochem , vol.165 , pp. 215-219
    • Halliwell, B.1    Gutteridge, J.M.C.2    Aruoma, O.I.3
  • 43
    • 0036263238 scopus 로고    scopus 로고
    • High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes
    • Vozarova B, Stefan N, Lindsay RS, Saremi A, Pratley RE, Bogardus C, et al. High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes. 2002; 51: 1889-95.
    • (2002) Diabetes , vol.51 , pp. 1889-1895
    • Vozarova, B.1    Stefan, N.2    Lindsay, R.S.3    Saremi, A.4    Pratley, R.E.5    Bogardus, C.6
  • 44
    • 4344698262 scopus 로고    scopus 로고
    • Hepatoprotective effect of Epaltes divaricatta extract on tetrachloride induced hepatotoxicity in mice
    • Hewawasam RP, Jayatilaka KAPW, Pthinrana C, Mudduwa LKB. Hepatoprotective effect of Epaltes divaricatta extract on tetrachloride induced hepatotoxicity in mice. Indian J Med Res. 2004; 120: 30-4.
    • (2004) Indian J Med Res , vol.120 , pp. 30-34
    • Hewawasam, R.P.1    Jayatilaka, K.A.P.W.2    Pthinrana, C.3    Mudduwa, L.K.B.4
  • 45
    • 33746521801 scopus 로고
    • The cellular basis of hepatic fibrosis: Mechanisms and treatment strategies
    • Friedman SL. The cellular basis of hepatic fibrosis: mechanisms and treatment strategies. N Engl J Med. 1993; 328: 1828-35.
    • (1993) N Engl J Med , vol.328 , pp. 1828-1835
    • Friedman, S.L.1
  • 46
    • 18744393745 scopus 로고    scopus 로고
    • 4 administration in the rat after discontinuation of treatment: Effect of silymarin, silibinin, colchicine and trimethylcolchicinic acid
    • 4 administration in the rat after discontinuation of treatment: effect of silymarin, silibinin, colchicine and trimethylcolchicinic acid. Basic Clin Pharmacol Toxicol. 2005; 96: 375-80.
    • (2005) Basic Clin Pharmacol Toxicol , vol.96 , pp. 375-380
    • Muriel, P.1    Moreno, M.G.2    Hernandez, M.3    Del, C.4
  • 47
    • 0027234009 scopus 로고
    • Liver damage due to free radicals
    • Poli G. Liver damage due to free radicals. Brit Med Bull. 1993; 49: 604-20.
    • (1993) Brit Med Bull , vol.49 , pp. 604-620
    • Poli, G.1
  • 48
    • 33749262660 scopus 로고    scopus 로고
    • Comparison of the effects of melatonin and pentoxifylline on carbon tetrachloride-induced liver toxicity in mice
    • Noyan T, Kömüroglu U, Bayram I, Sekeroglu MR. Comparison of the effects of melatonin and pentoxifylline on carbon tetrachloride-induced liver toxicity in mice. Cell Biol Toxicol. 2006; 22: 381-91.
    • (2006) Cell Biol Toxicol , vol.22 , pp. 381-391
    • Noyan, T.1    Kömüroglu, U.2    Bayram, I.3    Sekeroglu, M.R.4
  • 49
    • 41549163847 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 aggravates secretory phospholipase A2-mediated progression of acute live injury
    • Bhave SV, Donthamsetty S, Latendesse JR, Mehendale HM. Inhibition of cyclooxygenase-2 aggravates secretory phospholipase A2-mediated progression of acute live injury. Toxicol Appl Pharmacol. 2008; 228: 239-46.
    • (2008) Toxicol Appl Pharmacol , vol.228 , pp. 239-246
    • Bhave, S.V.1    Donthamsetty, S.2    Latendesse, J.R.3    Mehendale, H.M.4
  • 50
    • 0025602718 scopus 로고
    • Carbon tetrachloride hepatotoxicity: An example of free radical-mediated injury
    • Williams AT, Burk RF. Carbon tetrachloride hepatotoxicity: an example of free radical-mediated injury. Semin Liver Dis. 1990; 10: 279-84.
    • (1990) Semin Liver Dis , vol.10 , pp. 279-284
    • Williams, A.T.1    Burk, R.F.2


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