메뉴 건너뛰기




Volumn 194, Issue 9, 2015, Pages 4489-4497

Vibsanin B preferentially targets HSP90β, inhibits interstitial leukocyte migration, and ameliorates experimental autoimmune encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

DITERPENOID; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 90 BETA; PROTEIN KINASE B; UNCLASSIFIED DRUG; VIBSANIN B; DITERPENE; HEAT SHOCK PROTEIN 90;

EID: 84928482508     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402798     Document Type: Article
Times cited : (24)

References (46)
  • 1
    • 50049109579 scopus 로고    scopus 로고
    • Interstitial leukocyte migration and immune function
    • Friedl, P., and B. Weigelin. 2008. Interstitial leukocyte migration and immune function. Nat. Immunol. 9: 960-969.
    • (2008) Nat. Immunol. , vol.9 , pp. 960-969
    • Friedl, P.1    Weigelin, B.2
  • 2
    • 77950365906 scopus 로고    scopus 로고
    • Nonresolving inflammation
    • Nathan, C., and A. Ding. 2010. Nonresolving inflammation. Cell 140: 871-882.
    • (2010) Cell , vol.140 , pp. 871-882
    • Nathan, C.1    Ding, A.2
  • 3
    • 50049089619 scopus 로고    scopus 로고
    • Moving targets: Cell migration inhibitors as new anti-inflammatory therapies
    • Mackay, C. R. 2008. Moving targets: cell migration inhibitors as new anti-inflammatory therapies. Nat. Immunol. 9: 988-998.
    • (2008) Nat. Immunol. , vol.9 , pp. 988-998
    • Mackay, C.R.1
  • 4
    • 80052246111 scopus 로고    scopus 로고
    • Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
    • Ajami, B., J. L. Bennett, C. Krieger, K. M. McNagny, and F. M. Rossi. 2011. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat. Neurosci. 14: 1142-1149.
    • (2011) Nat. Neurosci. , vol.14 , pp. 1142-1149
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    McNagny, K.M.4    Rossi, F.M.5
  • 5
    • 84885773340 scopus 로고    scopus 로고
    • Zebrafish: A multifaceted tool for chemical biologists
    • Basu, S., and C. Sachidanandan. 2013. Zebrafish: a multifaceted tool for chemical biologists. Chem. Rev. 113: 7952-7980.
    • (2013) Chem. Rev. , vol.113 , pp. 7952-7980
    • Basu, S.1    Sachidanandan, C.2
  • 6
    • 12144273121 scopus 로고    scopus 로고
    • In vivo drug discovery in the zebrafish
    • Zon, L. I., and R. T. Peterson. 2005. In vivo drug discovery in the zebrafish. Nat. Rev. Drug Discov. 4: 35-44.
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 35-44
    • Zon, L.I.1    Peterson, R.T.2
  • 7
    • 34247186766 scopus 로고    scopus 로고
    • Animal models of human disease: Zebrafish swim into view
    • Lieschke, G. J., and P. D. Currie. 2007. Animal models of human disease: zebrafish swim into view. Nat. Rev. Genet. 8: 353-367.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 353-367
    • Lieschke, G.J.1    Currie, P.D.2
  • 9
    • 49649101876 scopus 로고    scopus 로고
    • In vivo interstitial migration of primitive macrophages mediated by JNK-matrix metalloproteinase 13 signaling in response to acute injury
    • Zhang, Y., X. T. Bai, K. Y. Zhu, Y. Jin, M. Deng, H. Y. Le, Y. F. Fu, Y. Chen, J. Zhu, A. T. Look, et al. 2008. In vivo interstitial migration of primitive macrophages mediated by JNK-matrix metalloproteinase 13 signaling in response to acute injury. J. Immunol. 181: 2155-2164.
    • (2008) J. Immunol. , vol.181 , pp. 2155-2164
    • Zhang, Y.1    Bai, X.T.2    Zhu, K.Y.3    Jin, Y.4    Deng, M.5    Le, H.Y.6    Fu, Y.F.7    Chen, Y.8    Zhu, J.9    Look, A.T.10
  • 10
    • 67649255876 scopus 로고    scopus 로고
    • A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
    • Niethammer, P., C. Grabher, A. T. Look, and T. J. Mitchison. 2009. A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature 459: 996-999.
    • (2009) Nature , vol.459 , pp. 996-999
    • Niethammer, P.1    Grabher, C.2    Look, A.T.3    Mitchison, T.J.4
  • 11
    • 84902128176 scopus 로고    scopus 로고
    • IL-1β and reactive oxygen species differentially regulate neutrophil directional migration and basal random motility in a zebrafish injury-induced inflammation model
    • Yan, B., P. Han, L. Pan, W. Lu, J. Xiong, M. Zhang, W. Zhang, L. Li, and Z. Wen. 2014. IL-1β and reactive oxygen species differentially regulate neutrophil directional migration and basal random motility in a zebrafish injury-induced inflammation model. J. Immunol. 192: 5998-6008.
    • (2014) J. Immunol. , vol.192 , pp. 5998-6008
    • Yan, B.1    Han, P.2    Pan, L.3    Lu, W.4    Xiong, J.5    Zhang, M.6    Zhang, W.7    Li, L.8    Wen, Z.9
  • 12
    • 84877697688 scopus 로고    scopus 로고
    • Cannabinoid receptor 2 suppresses leukocyte inflammatory migration by modulating the JNK/c-Jun/Alox5 pathway
    • Liu, Y. J., H. B. Fan, Y. Jin, C. G. Ren, X. E. Jia, L. Wang, Y. Chen, M. Dong, K. Y. Zhu, Z. W. Dong, et al. 2013. Cannabinoid receptor 2 suppresses leukocyte inflammatory migration by modulating the JNK/c-Jun/Alox5 pathway. J. Biol. Chem. 288: 13551-13562.
    • (2013) J. Biol. Chem. , vol.288 , pp. 13551-13562
    • Liu, Y.J.1    Fan, H.B.2    Jin, Y.3    Ren, C.G.4    Jia, X.E.5    Wang, L.6    Chen, Y.7    Dong, M.8    Zhu, K.Y.9    Dong, Z.W.10
  • 14
    • 77953916528 scopus 로고    scopus 로고
    • HSP90 at the hub of protein homeostasis: Emerging mechanistic insights
    • Taipale, M., D. F. Jarosz, and S. Lindquist. 2010. HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat. Rev. Mol. Cell Biol. 11: 515-528.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 515-528
    • Taipale, M.1    Jarosz, D.F.2    Lindquist, S.3
  • 16
  • 17
    • 78650734840 scopus 로고    scopus 로고
    • HSP90 modulates actin dynamics: Inhibition of HSP90 leads to decreased cell motility and impairs invasion
    • Taiyab, A., and ChM. Rao. 2011. HSP90 modulates actin dynamics: inhibition of HSP90 leads to decreased cell motility and impairs invasion. Biochim. Biophys. Acta 1813: 213-221.
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 213-221
    • Taiyab, A.1    Rao, C.2
  • 18
    • 77954897360 scopus 로고    scopus 로고
    • Cancer dissemination - Lessons from leukocytes
    • Madsen, C. D., and E. Sahai. 2010. Cancer dissemination - lessons from leukocytes. Dev. Cell 19: 13-26.
    • (2010) Dev. Cell , vol.19 , pp. 13-26
    • Madsen, C.D.1    Sahai, E.2
  • 19
    • 79251588744 scopus 로고    scopus 로고
    • EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity
    • Yun, T. J., E. K. Harning, K. Giza, D. Rabah, P. Li, J. W. Arndt, D. Luchetti, M. A. Biamonte, J. Shi, K. Lundgren, et al. 2011. EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity. J. Immunol. 186: 563-575.
    • (2011) J. Immunol. , vol.186 , pp. 563-575
    • Yun, T.J.1    Harning, E.K.2    Giza, K.3    Rabah, D.4    Li, P.5    Arndt, J.W.6    Luchetti, D.7    Biamonte, M.A.8    Shi, J.9    Lundgren, K.10
  • 21
    • 79751510152 scopus 로고    scopus 로고
    • Chemistry and biological activities of vibsane-type diterpenoids
    • Fukuyama, Y., M. Kubo, T. Esumi, K. Harada, and H. Hioki. 2010. Chemistry and biological activities of vibsane-type diterpenoids. Heterocycles 81: 1571-1602.
    • (2010) Heterocycles , vol.81 , pp. 1571-1602
    • Fukuyama, Y.1    Kubo, M.2    Esumi, T.3    Harada, K.4    Hioki, H.5
  • 22
    • 84863116492 scopus 로고    scopus 로고
    • Bortezomib interferes with C-KIT processing and transforms the t(8;21)-generated fusion proteins into tumor-suppressing fragments in leukemia cells
    • Fang, H. T., B. Zhang, X. F. Pan, L. Gao, T. Zhen, H. X. Zhao, L. Ma, J. Xie, Z. Liu, X. J. Yu, et al. 2012. Bortezomib interferes with C-KIT processing and transforms the t(8;21)-generated fusion proteins into tumor-suppressing fragments in leukemia cells. Proc. Natl. Acad. Sci. USA 109: 2521-2526.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 2521-2526
    • Fang, H.T.1    Zhang, B.2    Pan, X.F.3    Gao, L.4    Zhen, T.5    Zhao, H.X.6    Ma, L.7    Xie, J.8    Liu, Z.9    Yu, X.J.10
  • 23
    • 77955511758 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces chemotactic migration of monocytes via a death receptor 4-mediated RhoGTPase pathway
    • Wei, W., D. Wang, J. Shi, Y. Xiang, Y. Zhang, S. Liu, Y. Liu, and D. Zheng. 2010. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces chemotactic migration of monocytes via a death receptor 4-mediated RhoGTPase pathway. Mol. Immunol. 47: 2475-2484.
    • (2010) Mol. Immunol. , vol.47 , pp. 2475-2484
    • Wei, W.1    Wang, D.2    Shi, J.3    Xiang, Y.4    Zhang, Y.5    Liu, S.6    Liu, Y.7    Zheng, D.8
  • 24
    • 77449103494 scopus 로고    scopus 로고
    • Manipulation of neutrophil-like HL-60 cells for the study of directed cell migration
    • Millius, A., and O. D. Weiner. 2010. Manipulation of neutrophil-like HL-60 cells for the study of directed cell migration. Methods Mol. Biol. 591: 147-158.
    • (2010) Methods Mol. Biol. , vol.591 , pp. 147-158
    • Millius, A.1    Weiner, O.D.2
  • 27
    • 34047237073 scopus 로고    scopus 로고
    • Hsp90 selectively modulates phenotype in vertebrate development
    • Available at
    • Yeyati, P. L., R. M. Bancewicz, J. Maule, and V. van Heyningen. 2007. Hsp90 selectively modulates phenotype in vertebrate development. PLoS Genet. 3: e43. Available at: http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.0030043#pgen-0030043-g009.
    • (2007) PLoS Genet. , vol.3 , pp. e43
    • Yeyati, P.L.1    Bancewicz, R.M.2    Maule, J.3    Van Heyningen, V.4
  • 29
    • 34248647881 scopus 로고    scopus 로고
    • Active induction of experimental allergic encephalomyelitis
    • Stromnes, I. M., and J. M. Goverman. 2006. Active induction of experimental allergic encephalomyelitis. Nat. Protoc. 1: 1810-1819.
    • (2006) Nat. Protoc. , vol.1 , pp. 1810-1819
    • Stromnes, I.M.1    Goverman, J.M.2
  • 30
    • 84877627496 scopus 로고    scopus 로고
    • Characterization of migration parameters on peripheral and central nervous system T cells following treatment of experimental allergic encephalomyelitis with CRYAB
    • Oyebamiji, A. I., T. M. Finlay, R. M. Hough, V. Hoghooghi, E. M. Lim, C. H. Wong, and S. S. Ousman. 2013. Characterization of migration parameters on peripheral and central nervous system T cells following treatment of experimental allergic encephalomyelitis with CRYAB. J. Neuroimmunol. 259: 66-74.
    • (2013) J. Neuroimmunol. , vol.259 , pp. 66-74
    • Oyebamiji, A.I.1    Finlay, T.M.2    Hough, R.M.3    Hoghooghi, V.4    Lim, E.M.5    Wong, C.H.6    Ousman, S.S.7
  • 32
    • 76249109093 scopus 로고    scopus 로고
    • Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish
    • Yoo, S. K., Q. Deng, P. J. Cavnar, Y. I. Wu, K. M. Hahn, and A. Huttenlocher. 2010. Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish. Dev. Cell 18: 226-236.
    • (2010) Dev. Cell , vol.18 , pp. 226-236
    • Yoo, S.K.1    Deng, Q.2    Cavnar, P.J.3    Wu, Y.I.4    Hahn, K.M.5    Huttenlocher, A.6
  • 33
    • 33750945303 scopus 로고    scopus 로고
    • The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis
    • Dello Russo, C., P. E. Polak, P. R. Mercado, A. Spagnolo, A. Sharp, P. Murphy, A. Kamal, F. J. Burrows, L. C. Fritz, and D. L. Feinstein. 2006. The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis. J. Neurochem. 99: 1351-1362.
    • (2006) J. Neurochem. , vol.99 , pp. 1351-1362
    • Dello Russo, C.1    Polak, P.E.2    Mercado, P.R.3    Spagnolo, A.4    Sharp, A.5    Murphy, P.6    Kamal, A.7    Burrows, F.J.8    Fritz, L.C.9    Feinstein, D.L.10
  • 34
    • 79251580358 scopus 로고    scopus 로고
    • CCL22 regulates experimental autoimmune encephalomyelitis by controlling inflammatory macrophage accumulation and effector function
    • Dogan, R. N., N. Long, E. Forde, K. Dennis, A. P. Kohm, S. D. Miller, and W. J. Karpus. 2011. CCL22 regulates experimental autoimmune encephalomyelitis by controlling inflammatory macrophage accumulation and effector function. J. Leukoc. Biol. 89: 93-104.
    • (2011) J. Leukoc. Biol. , vol.89 , pp. 93-104
    • Dogan, R.N.1    Long, N.2    Forde, E.3    Dennis, K.4    Kohm, A.P.5    Miller, S.D.6    Karpus, W.J.7
  • 35
    • 27144547510 scopus 로고    scopus 로고
    • Chemistry. The renaissance of natural products as drug candidates
    • Paterson, I., and E. A. Anderson. 2005. Chemistry. The renaissance of natural products as drug candidates. Science 310: 451-453.
    • (2005) Science , vol.310 , pp. 451-453
    • Paterson, I.1    Anderson, E.A.2
  • 36
    • 67650436176 scopus 로고    scopus 로고
    • Drug discovery and natural products: End of an era or an endless frontier?
    • Li, J. W. H., and J. C. Vederas. 2009. Drug discovery and natural products: end of an era or an endless frontier? Science 325: 161-165.
    • (2009) Science , vol.325 , pp. 161-165
    • Li, J.W.H.1    Vederas, J.C.2
  • 37
    • 84861122896 scopus 로고    scopus 로고
    • Key achievements in the total synthesis of vibsane-type diterpenoids
    • Mak, J. Y. W., and C. M. Williams. 2012. Key achievements in the total synthesis of vibsane-type diterpenoids. Nat. Prod. Rep. 29: 440-448.
    • (2012) Nat. Prod. Rep. , vol.29 , pp. 440-448
    • Mak, J.Y.W.1    Williams, C.M.2
  • 40
    • 50649112213 scopus 로고    scopus 로고
    • Activity-based protein profiling: From enzyme chemistry to proteomic chemistry
    • Cravatt, B. F., A. T. Wright, and J. W. Kozarich. 2008. Activity-based protein profiling: from enzyme chemistry to proteomic chemistry. Annu. Rev. Biochem. 77: 383-414.
    • (2008) Annu. Rev. Biochem. , vol.77 , pp. 383-414
    • Cravatt, B.F.1    Wright, A.T.2    Kozarich, J.W.3
  • 43
    • 61649098007 scopus 로고    scopus 로고
    • Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket
    • Donnelly, A., and B. S. Blagg. 2008. Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket. Curr. Med. Chem. 15: 2702-2717.
    • (2008) Curr. Med. Chem. , vol.15 , pp. 2702-2717
    • Donnelly, A.1    Blagg, B.S.2
  • 44
    • 0034718540 scopus 로고    scopus 로고
    • Modulation of Akt kinase activity by binding to Hsp90
    • Sato, S., N. Fujita, and T. Tsuruo. 2000. Modulation of Akt kinase activity by binding to Hsp90. Proc. Natl. Acad. Sci. USA 97: 10832-10837.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10832-10837
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 45
    • 78349289202 scopus 로고    scopus 로고
    • Pharmacological management of symptoms in multiple sclerosis: Current approaches and future directions
    • Thompson, A. J., A. T. Toosy, and O. Ciccarelli. 2010. Pharmacological management of symptoms in multiple sclerosis: current approaches and future directions. Lancet Neurol. 9: 1182-1199.
    • (2010) Lancet Neurol. , vol.9 , pp. 1182-1199
    • Thompson, A.J.1    Toosy, A.T.2    Ciccarelli, O.3
  • 46
    • 76449110495 scopus 로고    scopus 로고
    • Combination therapy in multiple sclerosis
    • Conway, D., and J. A. Cohen. 2010. Combination therapy in multiple sclerosis. Lancet Neurol. 9: 299-308.
    • (2010) Lancet Neurol. , vol.9 , pp. 299-308
    • Conway, D.1    Cohen, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.