A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism

Science Translational Medicine

Volumn 6, Issue 225, 2014, Pages

  Robertson, Anne L ^a   Holmes, Geoffrey R ^a   Bojarczuk, Aleksandra N ^a   Burgon, Joseph ^a   Loynes, Catherine A ^a   Chimen, Myriam ^b   Sawtell, Amy K ^c   Hamza, Bashar ^d   Willson, Joseph ^a   Walmsley, Sarah R ^a   Anderson, Sean R ^a   Coles, Mark C ^c   Farrow, Stuart N ^e   Solari, Roberto ^f   Jones, Simon ^a   Prince, Lynne R ^a   Irimia, Daniel ^d   Ed Rainger, G ^b   Kadirkamanathan, Visakan ^a   Whyte, Moira K B ^a   Renshaw, Stephen A ^a   more..

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF YORK   (United Kingdom)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e GLAXOSMITHKLINE   (United Kingdom)

^f NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CRYPTOTANSHINONE; TANSHINONE IIA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; GENETIC SCREENING; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; LEUKOCYTE FUNCTION; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NEUTROPHIL REVERSE MIGRATION; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC ANIMAL; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; CELL MOVEMENT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; GREEN FLUORESCENT PROTEINS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INFLAMMATION; LARVA; NEUTROPHIL INFILTRATION; NEUTROPHILS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSLATIONAL MEDICAL RESEARCH; ZEBRAFISH;

EID: 84896382045     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3007672     Document Type: Article

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