Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces chemotactic migration of monocytes via a death receptor 4-mediated RhoGTPase pathway

Molecular Immunology

Volumn 47, Issue 15, 2010, Pages 2475-2484

  Wei, Wei ^a   Wang, Dongsheng ^a   Shi, Juan ^a   Xiang, Yang ^a   Zhang, Yaxi ^a   Liu, Shilian ^a   Liu, Yanxin ^a   Zheng, Dexian ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Migration; Monocyte; Phosphatidylinositol 3 kinase (PI3K); Rho; Tumor necrosis factor (TNF) related apoptosis inducing ligand (TRAIL)

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; DEATH RECEPTOR 4; LIPOPOLYSACCHARIDE; P21 ACTIVATED KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; WORTMANNIN;

ARTICLE; CELL MIGRATION; CHEMOTAXIS; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKEMIA CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 77955511758     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.06.004     Document Type: Article

References (55)

1. Alessi D.R., James S.R., Downes C.P., Holmes A.B., Gaffney P.R., Reese C.B., Cohen P. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Curr. Biol. 1997, 7:261-269.
2. Bakin A.V., Tomlinson A.K., Bhowmick N.A., Moses H.L., Arteaga C.L. Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration. J. Biol. Chem. 2000, 275:36803-36810.
3. Burger D. Cell contact-mediated signaling of monocytes by stimulated T cells: a major pathway for cytokine induction. Eur. Cytokine Netw. 2000, 11:346-353.
4. Cantley L.C. The phosphoinositide 3-kinase pathway. Science 2002, 296:1655-1657.
5. Chen Y., Kam C.S., Liu F.Q., Liu Y., Lui V.C., Lamb J.R., Tam P.K. LPS-induced up-regulation of TGF-beta receptor 1 is associated with TNF-alpha expression in human monocyte-derived macrophages. J. Leukoc. Biol. 2008, 83:1165-1173.
6. Chugh P., Fan S., Planelles V., Maggirwar S.B., Dewhurst S., Kim B. Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line. J. Mol. Biol. 2007, 366:67-81.
7. Cretney E., Takeda K., Yagita H., Glaccum M., Peschon J.J., Smyth M.J. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J. Immunol. 2002, 168:1356-1361.
8. Das B., Shu X., Day G.J., Han J., Krishna U.M., Falck J.R., Broek D. Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding. J. Biol. Chem. 2000, 275:15074-15081.
9. Debidda M., Wang L., Zang H., Poli V., Zheng Y. A role of STAT3 in Rho GTPase-regulated cell migration and proliferation. J. Biol. Chem. 2005, 280:17275-17285.
10. Ehrhardt H., Fulda S., Schmid I., Hiscott J., Debatin K.M., Jeremias I. TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB. Oncogene 2003, 22:3842-3852.
11. Etienne-Manneville S., Hall A. Rho GTPases in cell biology. Nature 2002, 420:629-635.
12. Fanger N.A., Maliszewski C.R., Schooley K., Griffith T.S. Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). J. Exp. Med. 1999, 190:1155-1164.
13. Fleming I.N., Gray A., Downes C.P. Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components. Biochem. J. 2000, 351:173-182.
14. Gamell C., Osses N., Bartrons R., Ruckle T., Camps M., Rosa J.L., Ventura F. BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity. J. Cell Sci. 2008, 121:3960-3970.
15. Griffith T.S., Wiley S.R., Kubin M.Z., Sedger L.M., Maliszewski C.R., Fanger N.A. Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine. TRAIL. J. Exp. Med. 1999, 189:1343-1354.
16. Grosse-Wilde A., Voloshanenko O., Bailey S.L., Longton G.M., Schaefer U., Csernok A.I., Schutz G., Greiner E.F., Kemp C.J., Walczak H. TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development. J. Clin. Invest. 2008, 118:100-110.
17. Halaas O., Vik R., Ashkenazi A., Espevik T. Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages. Scand. J. Immunol. 2000, 51:244-250.
18. Herbeuval J.P., Boasso A., Grivel J.C., Hardy A.W., Anderson S.A., Dolan M.J., Chougnet C., Lifson J.D., Shearer G.M. TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells. Blood 2005, 105:2458-2464.
19. Hilliard B., Wilmen A., Seidel C., Liu T.S., Goke R., Chen Y. Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis. J. Immunol. 2001, 166:1314-1319.
20. Ichikawa K., Liu W., Fleck M., Zhang H., Zhao L., Ohtsuka T., Wang Z., Liu D., Mountz J.D., Ohtsuki M., Koopman W.J., Kimberly R., Zhou T. TRAIL-R2 (DR5) mediates apoptosis of synovial fibroblasts in rheumatoid arthritis. J. Immunol. 2003, 171:1061-1069.
21. Ishikawa E., Nakazawa M., Yoshinari M., Minami M. Role of tumor necrosis factor-related apoptosis-inducing ligand in immune response to influenza virus infection in mice. J. Virol. 2005, 79:7658-7663.
22. Ishimura N., Isomoto H., Bronk S.F., Gores G.J. Trail induces cell migration and invasion in apoptosis-resistant cholangiocarcinoma cells. Am. J. Physiol. Gastrointest. Liver Physiol. 2006, 290:129-136.
23. Kintscher C., Groemping Y. Characterisation of the nucleotide exchange factor ITSN1L: evidence for a kinetic discrimination of GEF-stimulated nucleotide release from Cdc42. J. Mol. Biol. 2009, 387:270-283.
24. Kurbanov B.M., Geilen C.C., Fecker L.F., Orfanos C.E., Eberle J. Efficient TRAIL-R1/DR4-mediated apoptosis in melanoma cells by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). J. Invest. Dermatol. 2005, 125:1010-1019.
25. Le Y., Gong W., Li B., Dunlop N.M., Shen W., Su S.B., Ye R.D., Wang J.M. Utilization of two seven-transmembrane, G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activation. J. Immunol. 1999, 163:6777-6784.
26. Lin C., Wei W., Zhang J., Liu S., Liu Y., Zheng D. Formyl peptide receptor-like 1 mediated endogenous TRAIL gene expression with tumoricidal activity. Mol. Cancer Ther. 2007, 6:2618-2625.
27. Lub-de Hooge M.N., de Vries E.G., de Jong S., Bijl M. Soluble TRAIL concentrations are raised in patients with systemic lupus erythematosus. Ann. Rheum. Dis. 2005, 64:854-858.
28. Manzo F., Nebbioso A., Miceli M., Conte M., De Bellis F., Carafa V., Franci G., Tambaro F.P., Altucci L. TNF-related apoptosis-inducing ligand: signalling of a 'smart' molecule. Int. J. Biochem. Cell Biol. 2009, 41:460-466.
29. Morel J., Audo R., Hahne M., Combe B. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt. J. Biol. Chem. 2005, 280:15709-15718.
30. Perlman H., Pagliari L.J., Nguyen N., Bradley K., Liu H., Pope R.M. The Fas-FasL death receptor and PI3K pathways independently regulate monocyte homeostasis. Eur. J. Immunol. 2001, 31:2421-2430.
31. Phillips T.A., Ni J., Pan G., Ruben S.M., Wei Y.F., Pace J.L., Hunt J.S. TRAIL (Apo-2L) and TRAIL receptors in human placentas: implications for immune privilege. J. Immunol. 1999, 162:6053-6059.
32. Pitti R.M., Marsters S.A., Ruppert S., Donahue C.J., Moore A., Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem. 1996, 271:12687-12690.
33. Postlethwaite A.E., Seyer J.M. Stimulation of fibroblast chemotaxis by human recombinant tumor necrosis factor alpha (TNF-alpha) and a synthetic TNF-alpha 31-68 peptide. J. Exp. Med. 1990, 172:1749-1756.
34. Renshaw S.A., Parmar J.S., Singleton V., Rowe S.J., Dockrell D.H., Dower S.K., Bingle C.D., Chilvers E.R., Whyte M.K. Acceleration of human neutrophil apoptosis by TRAIL. J. Immunol. 2003, 170:1027-1033.
35. Ridley A.J. Rho proteins, PI 3-kinases, and monocyte/macrophage motility. FEBS Lett. 2001, 498:168-171.
36. Sasaki A.T., Janetopoulos C., Lee S., Charest P.G., Takeda K., Sundheimer L.W., Meili R., Devreotes P.N., Firtel R.A. G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility. J. Cell Biol. 2007, 178:185-191.
37. Sato K., Hida S., Takayanagi H., Yokochi T., Kayagaki N., Takeda K., Yagita H., Okumura K., Tanaka N., Taniguchi T., Ogasawara K. Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta. Eur. J. Immunol. 2001, 31:3138-3146.
38. Schrader W., Schallhorn A., Grill B., Guo X. Activation of small GTPases of the Ras and Rho family by growth factors active on mast cells. Mol. Immunol. 2002, 38:1181-1186.
39. Secchiero P., Gonelli A., Carnevale E., Milani D., Pandolfi A., Zella D., Zauli G. TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways. Circulation 2003, 107:2250-2256.
40. Secchiero P., Gonelli A., Mirandola P., Melloni E., Zamai L., Celeghini C., Milani D., Zauli G. Tumor necrosis factor-related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway. Blood 2002, 100:2421-2429.
41. Secchiero P., Melloni E., Corallini F., Beltrami A.P., Alviano F., Milani D., D'Aurizio F., di Iasio M.G., Cesselli D., Bagnara G.P., Zauli G. Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells. Stem Cells 2008, 26:2955-2963.
42. Secchiero P., Melloni E., Heikinheimo M., Mannisto S., Di Pietro R., Iacone A., Zauli G. TRAIL regulates normal erythroid maturation through an ERK-dependent pathway. Blood 2004, 103:517-522.
43. Secchiero P., Zerbinati C., Rimondi E., Corallini F., Milani D., Grill V., Forti G., Capitani S., Zauli G. TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells. Cell. Mol. Life Sci. 2004, 61:1965-1974.
44. Seki N., Hayakawa Y., Brooks A.D., Wine J., Wiltrout R.H., Yagita H., Tanner J.E., Smyth M.J., Sayers T.J. Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer. Cancer Res. 2003, 63:207-213.
45. Smith M.S., Bentz G.L., Smith P.M., Bivins E.R., Yurochko A.D. HCMV activates PI(3)K in monocytes and promotes monocyte motility and transendothelial migration in a PI(3)K-dependent manner. J. Leukoc. Biol. 2004, 76:65-76.
46. Sova P., Ren X.W., Ni S., Bernt K.M., Mi J., Kiviat N., Lieber A. A tumor-targeted and conditionally replicating oncolytic adenovirus vector expressing TRAIL for treatment of liver metastases. Mol. Ther. 2004, 9:496-509.
47. Subauste M.C., Von Herrath M., Benard V., Chamberlain C.E., Chuang T.H., Chu K., Bokoch G.M., Hahn K.M. Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas. J. Biol. Chem. 2000, 275:9725-9733.
48. Takeda K., Hayakawa Y., Smyth M.J., Kayagaki N., Yamaguchi N., Kakuta S., Iwakura Y., Yagita H., Okumura K. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat. Med. 2001, 7:94-100.
49. Walczak H., Krammer P.H. The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp. Cell Res. 2000, 256:58-66.
50. Wiley S.R., Schooley K., Smolak P.J., Din W.S., Huang C.P., Nicholl J.K., Sutherland G.R., Smith T.D., Rauch C., Smith C.A., et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995, 3:673-682.
51. Woodring P.J., Hunter T., Wang J.Y. Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases. J. Cell Sci. 2003, 116:2613-2626.
52. Yen M., Tsai H., Wu Y., Hwa H., Lee B., Hsu P. TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation from monocyte/macrophage lineage precursor cells. Mol. Immunol. 2008, 45:2205-2213.
53. Zauli G., Pandolfi A., Gonelli A., Di Pietro R., Guarnieri S., Ciabattoni G., Rana R., Vitale M., Secchiero P. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cells. Circ. Res. 2003, 92:732-740.
54. Zhang X.D., Borrow J.M., Zhang X.Y., Nguyen T., Hersey P. Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria. Oncogene 2003, 22:2869-2881.
55. Zuo X., Zhang J., Zhang Y., Hsu S.C., Zhou D., Guo W. Exo70 interacts with the Arp2/3 complex and regulates cell migration. Nat. Cell Biol. 2006, 8:1383-1388.