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Volumn 6, Issue , 2015, Pages

Interactions between horizontally acquired genes create a fitness cost in Pseudomonas aeruginosa

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE; TRANSFER RNA METHYLTRANSFERASE; BACTERIAL PROTEIN; BACTERIAL RNA;

EID: 84928402541     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7845     Document Type: Article
Times cited : (133)

References (53)
  • 1
    • 0034682335 scopus 로고    scopus 로고
    • Lateral gene transfer and the nature of bacterial innovation
    • Ochman, H., Lawrence, J. G. & Groisman, E. A. Lateral gene transfer and the nature of bacterial innovation. Nature 405, 299-304 (2000).
    • (2000) Nature , vol.405 , pp. 299-304
    • Ochman, H.1    Lawrence, J.G.2    Groisman, E.A.3
  • 2
    • 79960961566 scopus 로고    scopus 로고
    • Origins of bacterial diversity through horizontal genetic transfer and adaptation to new ecological niches
    • Wiedenbeck, J. & Cohan, F. M. Origins of bacterial diversity through horizontal genetic transfer and adaptation to new ecological niches. FEMS Microbiol. Rev. 35, 957-976 (2011).
    • (2011) FEMS Microbiol. Rev. , vol.35 , pp. 957-976
    • Wiedenbeck, J.1    Cohan, F.M.2
  • 3
    • 84880748808 scopus 로고    scopus 로고
    • Plasmids and the spread of resistance
    • Carattoli, A. Plasmids and the spread of resistance. Int. J. Med. Microbiol. 303, 298-304 (2013).
    • (2013) Int. J. Med. Microbiol. , vol.303 , pp. 298-304
    • Carattoli, A.1
  • 4
    • 33947260230 scopus 로고    scopus 로고
    • Molecular mechanisms of antibacterial multidrug resistance
    • Alekshun, M. N. & Levy, S. B. Molecular mechanisms of antibacterial multidrug resistance. Cell 128, 1037-1050 (2007).
    • (2007) Cell , vol.128 , pp. 1037-1050
    • Alekshun, M.N.1    Levy, S.B.2
  • 5
    • 84880712059 scopus 로고    scopus 로고
    • Exploring the costs of horizontal gene transfer
    • Baltrus, D. A. Exploring the costs of horizontal gene transfer. Trends Ecol. Evol. 28, 489-495 (2013).
    • (2013) Trends Ecol. Evol. , vol.28 , pp. 489-495
    • Baltrus, D.A.1
  • 6
    • 84925296085 scopus 로고    scopus 로고
    • The genetic basis of the fitness costs of antimicrobial resistance: A meta-analysis approach
    • Vogwill, T. & MacLean, R. C. The genetic basis of the fitness costs of antimicrobial resistance: a meta-analysis approach. Evol. Appl. doi:10.1111/eva.12202 8, 284-295 (2015).
    • (2015) Evol. Appl , vol.8 , pp. 284-295
    • Vogwill, T.1    MacLean, R.C.2
  • 7
    • 84910072410 scopus 로고    scopus 로고
    • Social behavior and decision making in bacterial conjugation
    • Koraimann, G. & Wagner, M. A. Social behavior and decision making in bacterial conjugation. Front. Cell Infect. Microbiol. 4, 54 (2014).
    • (2014) Front. Cell Infect. Microbiol. , vol.4 , pp. 54
    • Koraimann, G.1    Wagner, M.A.2
  • 8
    • 3142514466 scopus 로고    scopus 로고
    • The impact of prophages on bacterial chromosomes
    • Canchaya, C., Fournous, G. & Brüssow, H. The impact of prophages on bacterial chromosomes. Mol. Microbiol. 53, 9-18 (2004).
    • (2004) Mol. Microbiol. , vol.53 , pp. 9-18
    • Canchaya, C.1    Fournous, G.2    Brüssow, H.3
  • 9
    • 58149354386 scopus 로고    scopus 로고
    • Protein material costs: Single atoms can make an evolutionary difference
    • Bragg, J. G. & Wagner, A. Protein material costs: single atoms can make an evolutionary difference. Trends Genet. 25, 5-8 (2009).
    • (2009) Trends Genet. , vol.25 , pp. 5-8
    • Bragg, J.G.1    Wagner, A.2
  • 10
    • 77953115788 scopus 로고    scopus 로고
    • Cost of unneeded proteins in E. Coli is reduced after several generations in exponential growth
    • Shachrai, I., Zaslaver, A., Alon, U. & Dekel, E. Cost of unneeded proteins in E. coli is reduced after several generations in exponential growth. Mol. Cell. 38, 758-767 (2010).
    • (2010) Mol. Cell. , vol.38 , pp. 758-767
    • Shachrai, I.1    Zaslaver, A.2    Alon, U.3    Dekel, E.4
  • 11
    • 27544449355 scopus 로고    scopus 로고
    • Horizontal gene transfer depends on gene content of the host
    • Pál, C., Papp, B. & Lercher, M. J. Horizontal gene transfer depends on gene content of the host. Bioinformatics 21 Suppl 2, ii222-223 (2005).
    • (2005) Bioinformatics , vol.21 , pp. ii222-223
    • Pál, C.1    Papp, B.2    Lercher, M.J.3
  • 12
    • 0022442553 scopus 로고
    • An inhibitor of SOS induction, specified by a plasmid locus in Escherichia coli
    • Bagdasarian, M. et al. An inhibitor of SOS induction, specified by a plasmid locus in Escherichia coli. Proc. Natl Acad. Sci. USA 83, 5723-5726 (1986).
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , pp. 5723-5726
    • Bagdasarian, M.1
  • 13
    • 84856575274 scopus 로고    scopus 로고
    • Rational engineering of Escherichia coli strains for plasmid biopharmaceutical manufacturing
    • Gonçalves, G. A., Bower, D. M., Prazeres, D. M., Monteiro, G. A. & Prather, K. L. Rational engineering of Escherichia coli strains for plasmid biopharmaceutical manufacturing. Biotechnol. J. 7, 251-261 (2012).
    • (2012) Biotechnol. J. , vol.7 , pp. 251-261
    • Gonçalves, G.A.1    Bower, D.M.2    Prazeres, D.M.3    Monteiro, G.A.4    Prather, K.L.5
  • 14
    • 79551674254 scopus 로고    scopus 로고
    • Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast
    • Geiler-Samerotte, K. A. et al. Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast. Proc. Natl Acad. Sci. USA 108, 680-685 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 680-685
    • Geiler-Samerotte, K.A.1
  • 15
    • 84864112797 scopus 로고    scopus 로고
    • High expression hampers horizontal gene transfer
    • Park, C. & Zhang, J. High expression hampers horizontal gene transfer. Genome Biol. Evol. 4, 523-532 (2012).
    • (2012) Genome Biol. Evol. , vol.4 , pp. 523-532
    • Park, C.1    Zhang, J.2
  • 16
    • 79952840493 scopus 로고    scopus 로고
    • The complexity hypothesis revisited: Connectivity rather than function constitutes a barrier to horizontal gene transfer
    • Cohen, O., Gophna, U. & Pupko, T. The complexity hypothesis revisited: connectivity rather than function constitutes a barrier to horizontal gene transfer. Mol. Biol. Evol. 28, 1481-1489 (2011).
    • (2011) Mol. Biol. Evol. , vol.28 , pp. 1481-1489
    • Cohen, O.1    Gophna, U.2    Pupko, T.3
  • 17
    • 39749170667 scopus 로고    scopus 로고
    • Complexity connectivity, and duplicability as barriers to lateral gene transfer
    • Wellner, A., Lurie, M. N. & Gophna, U. Complexity, connectivity, and duplicability as barriers to lateral gene transfer. Genome. Biol. 8, R156 (2007).
    • (2007) Genome. Biol. , vol.8 , pp. R156
    • Wellner, A.1    Lurie, M.N.2    Gophna, U.3
  • 18
    • 33746008173 scopus 로고    scopus 로고
    • Selective silencing of foreign DNA with low GC content by the H-NS protein in Salmonella
    • Navarre, W. W. et al. Selective silencing of foreign DNA with low GC content by the H-NS protein in Salmonella. Science 313, 236-238 (2006).
    • (2006) Science , vol.313 , pp. 236-238
    • Navarre, W.W.1
  • 19
    • 33846511690 scopus 로고    scopus 로고
    • An H-NS-like stealth protein aids horizontal DNA transmission in bacteria
    • Doyle, M. et al. An H-NS-like stealth protein aids horizontal DNA transmission in bacteria. Science 315, 251-252 (2007).
    • (2007) Science , vol.315 , pp. 251-252
    • Doyle, M.1
  • 20
    • 84923368060 scopus 로고    scopus 로고
    • Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids
    • San Millan, A. et al. Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids. Nat. Commun. 5, 5208 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 5208
    • San Millan, A.1
  • 21
    • 0038026189 scopus 로고    scopus 로고
    • Characterization of pNI10 plasmid in Pseudomonas, and the construction of an improved Escherichia and Pseudomonas shuttle vector, pNUK73
    • Itoh, N. et al. Characterization of pNI10 plasmid in Pseudomonas, and the construction of an improved Escherichia and Pseudomonas shuttle vector, pNUK73. Appl. Microbiol. Biotechnol. 61, 240-246 (2003).
    • (2003) Appl. Microbiol. Biotechnol. , vol.61 , pp. 240-246
    • Itoh, N.1
  • 22
    • 0034761801 scopus 로고    scopus 로고
    • The RepA protein of plasmid pSC101 controls Escherichia coli cell division through the SOS response
    • Ingmer, H., Miller, C. & Cohen, S. N. The RepA protein of plasmid pSC101 controls Escherichia coli cell division through the SOS response. Mol. Microbiol. 42, 519-526 (2001).
    • (2001) Mol. Microbiol. , vol.42 , pp. 519-526
    • Ingmer, H.1    Miller, C.2    Cohen, S.N.3
  • 23
    • 33749585217 scopus 로고    scopus 로고
    • Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin
    • Cirz, R. T., O'Neill, B. M., Hammond, J. A., Head, S. R. & Romesberg, F. E. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. J. Bacteriol. 188, 7101-7110 (2006).
    • (2006) J. Bacteriol. , vol.188 , pp. 7101-7110
    • Cirz, R.T.1    O'Neill, B.M.2    Hammond, J.A.3    Head, S.R.4    Romesberg, F.E.5
  • 24
    • 33749531431 scopus 로고    scopus 로고
    • Mini-Tn7 insertion in bacteria with single attTn7 sites: Example Pseudomonas aeruginosa
    • Choi, K. H. & Schweizer, H. P. mini-Tn7 insertion in bacteria with single attTn7 sites: example Pseudomonas aeruginosa. Nat. Protoc. 1, 153-161 (2006).
    • (2006) Nat. Protoc. , vol.1 , pp. 153-161
    • Choi, K.H.1    Schweizer, H.P.2
  • 25
    • 0032749718 scopus 로고    scopus 로고
    • Vitro transcription analysis of rpoD in Pseudomonas aeruginosa PAO1
    • Aramaki, H. & Fujita, M. In vitro transcription analysis of rpoD in Pseudomonas aeruginosa PAO1. FEMS Microbiol. Lett. 180, 311-316 (1999).
    • (1999) FEMS Microbiol. Lett. , vol.180 , pp. 311-316
    • Aramaki, H.1    Fujita, M.2
  • 26
    • 36849038974 scopus 로고    scopus 로고
    • Intracellular levels and activity of PvdS, the major iron starvation sigma factor of Pseudomonas aeruginosa
    • Tiburzi, F., Imperi, F. & Visca, P. Intracellular levels and activity of PvdS, the major iron starvation sigma factor of Pseudomonas aeruginosa. Mol. Microbiol. 67, 213-227 (2008).
    • (2008) Mol. Microbiol. , vol.67 , pp. 213-227
    • Tiburzi, F.1    Imperi, F.2    Visca, P.3
  • 27
    • 0027513320 scopus 로고
    • Cell division inhibitors SulA and MinCD prevent formation of the FtsZ ring
    • Bi, E. & Lutkenhaus, J. Cell division inhibitors SulA and MinCD prevent formation of the FtsZ ring. J. Bacteriol. 175, 1118-1125 (1993).
    • (1993) J. Bacteriol. , vol.175 , pp. 1118-1125
    • Bi, E.1    Lutkenhaus, J.2
  • 28
    • 75749158559 scopus 로고    scopus 로고
    • Genome diversity of Pseudomonas aeruginosa PAO1 laboratory strains
    • Klockgether, J. et al. Genome diversity of Pseudomonas aeruginosa PAO1 laboratory strains. J. Bacteriol. 192, 1113-1121 (2010).
    • (2010) J. Bacteriol. , vol.192 , pp. 1113-1121
    • Klockgether, J.1
  • 29
    • 78650305634 scopus 로고    scopus 로고
    • What traits are carried on mobile genetic elements, and why?
    • Rankin, D. J., Rocha, E. P. & Brown, S. P. What traits are carried on mobile genetic elements, and why? Heredity (Edinb) 106, 1-10 (2011).
    • (2011) Heredity (Edinb) , vol.106 , pp. 1-10
    • Rankin, D.J.1    Rocha, E.P.2    Brown, S.P.3
  • 30
    • 21844459185 scopus 로고    scopus 로고
    • The IncP-6 plasmid Rms149 consists of a small mobilizable backbone with multiple large insertions
    • Haines, A. S., Jones, K., Cheung, M. & Thomas, C. M. The IncP-6 plasmid Rms149 consists of a small mobilizable backbone with multiple large insertions. J. Bacteriol. 187, 4728-4738 (2005).
    • (2005) J. Bacteriol. , vol.187 , pp. 4728-4738
    • Haines, A.S.1    Jones, K.2    Cheung, M.3    Thomas, C.M.4
  • 31
    • 83055188823 scopus 로고    scopus 로고
    • Broad-host-range plasmids from agricultural soils have IncP-1 backbones with diverse accessory genes
    • Sen, D. et al. Broad-host-range plasmids from agricultural soils have IncP-1 backbones with diverse accessory genes. Appl. Environ. Microbiol. 77, 7975-7983 (2011).
    • (2011) Appl. Environ. Microbiol. , vol.77 , pp. 7975-7983
    • Sen, D.1
  • 32
    • 73849092816 scopus 로고    scopus 로고
    • Dispersal of carbapenemase blaVIM-1 gene associated with different Tn402 variants, mercury transposons, and conjugative plasmids in Enterobacteriaceae and Pseudomonas aeruginosa
    • Tato, M., Coque, T. M., Baquero, F. & Cantón, R. Dispersal of carbapenemase blaVIM-1 gene associated with different Tn402 variants, mercury transposons, and conjugative plasmids in Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 54, 320-327 (2010).
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 320-327
    • Tato, M.1    Coque, T.M.2    Baquero, F.3    Cantón, R.4
  • 33
    • 0037378570 scopus 로고    scopus 로고
    • Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: A transcriptome analysis
    • Schuster, M., Lostroh, C. P., Ogi, T. & Greenberg, E. P. Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J. Bacteriol. 185, 2066-2079 (2003).
    • (2003) J. Bacteriol. , vol.185 , pp. 2066-2079
    • Schuster, M.1    Lostroh, C.P.2    Ogi, T.3    Greenberg, E.P.4
  • 34
    • 84893304286 scopus 로고    scopus 로고
    • Deep sequencing analyses expands the Pseudomonas aeruginosa AmpR regulon to include small RNA-mediated regulation of iron acquisition, heat shock and oxidative stress response
    • Balasubramanian, D. et al. Deep sequencing analyses expands the Pseudomonas aeruginosa AmpR regulon to include small RNA-mediated regulation of iron acquisition, heat shock and oxidative stress response. Nucleic Acids Res. 42, 979-998 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. 979-998
    • Balasubramanian, D.1
  • 35
    • 44349111947 scopus 로고    scopus 로고
    • Host and invader impact of transfer of the clc genomic island into Pseudomonas aeruginosa PAO1
    • Gaillard, M., Pernet, N., Vogne, C., Hagenbüchle, O. & van der Meer, J. R. Host and invader impact of transfer of the clc genomic island into Pseudomonas aeruginosa PAO1. Proc. Natl Acad. Sci. USA 105, 7058-7063 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 7058-7063
    • Gaillard, M.1    Pernet, N.2    Vogne, C.3    Hagenbüchle, O.4    Van Der Meer, J.R.5
  • 37
    • 0037222240 scopus 로고    scopus 로고
    • Strategies for helicase recruitment and loading in bacteria
    • Konieczny, I. Strategies for helicase recruitment and loading in bacteria. EMBO Rep. 4, 37-41 (2003).
    • (2003) EMBO Rep. , vol.4 , pp. 37-41
    • Konieczny, I.1
  • 38
    • 79960959549 scopus 로고    scopus 로고
    • Pervasive sign epistasis between conjugative plasmids and drug-resistance chromosomal mutations
    • Silva, R. F. et al. Pervasive sign epistasis between conjugative plasmids and drug-resistance chromosomal mutations. PLoS Genet. 7, e1002181 (2011).
    • (2011) PLoS Genet. , vol.7 , pp. e1002181
    • Silva, R.F.1
  • 39
    • 84894324351 scopus 로고    scopus 로고
    • Positive epistasis between co-infecting plasmids promotes plasmid survival in bacterial populations
    • San Millan, A., Heilbron, K. & MacLean, R. C. Positive epistasis between co-infecting plasmids promotes plasmid survival in bacterial populations. ISME J. 8, 601-612 (2014).
    • (2014) ISME J. , vol.8 , pp. 601-612
    • San Millan, A.1    Heilbron, K.2    MacLean, R.C.3
  • 40
    • 84867049470 scopus 로고    scopus 로고
    • Staphylococcal pathogenicity island interference with helper phage reproduction is a paradigm of molecular parasitism
    • Ram, G. et al. Staphylococcal pathogenicity island interference with helper phage reproduction is a paradigm of molecular parasitism. Proc. Natl Acad. Sci. USA 109, 16300-16305 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 16300-16305
    • Ram, G.1
  • 41
    • 84867997033 scopus 로고    scopus 로고
    • ParI, an orphan ParA family protein from Pseudomonas putida KT2440-specific genomic island, interferes with the partition system of IncP-7 plasmids
    • Miyakoshi, M. et al. ParI, an orphan ParA family protein from Pseudomonas putida KT2440-specific genomic island, interferes with the partition system of IncP-7 plasmids. Environ. Microbiol. 14, 2946-2959 (2012).
    • (2012) Environ. Microbiol. , vol.14 , pp. 2946-2959
    • Miyakoshi, M.1
  • 42
    • 27744453560 scopus 로고    scopus 로고
    • Identification of plasmids by PCR-based replicon typing
    • Carattoli, A. et al. Identification of plasmids by PCR-based replicon typing. J. Microbiol. Methods 63, 219-228 (2005).
    • (2005) J. Microbiol. Methods , vol.63 , pp. 219-228
    • Carattoli, A.1
  • 43
    • 84856468953 scopus 로고    scopus 로고
    • NGS QC Toolkit: A toolkit for quality control of next generation sequencing data
    • Patel, R. K. & Jain, M. NGS QC Toolkit: a toolkit for quality control of next generation sequencing data. PLoS ONE 7, e30619 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e30619
    • Patel, R.K.1    Jain, M.2
  • 44
    • 77949587649 scopus 로고    scopus 로고
    • Fast and accurate long-read alignment with Burrows-Wheeler transform
    • Li, H. & Durbin, R. Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 26, 589-595 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 589-595
    • Li, H.1    Durbin, R.2
  • 45
    • 84928987900 scopus 로고    scopus 로고
    • HTSeq-A python framework to work with high-troughput sequencing data
    • Anders, S., Pyl, P. & Huber, W. HTSeq-A python framework to work with high-troughput sequencing data. Bioinformatics 31, 166-169 (2015).
    • (2015) Bioinformatics , vol.31 , pp. 166-169
    • Anders, S.1    Pyl, P.2    Huber, W.3
  • 46
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count data
    • Anders, S. & Huber, W. Differential expression analysis for sequence count data. Genome Biol. 11, R106 (2010).
    • (2010) Genome Biol. , vol.11 , pp. R106
    • Anders, S.1    Huber, W.2
  • 47
    • 84920903379 scopus 로고    scopus 로고
    • Linking system-wide impacts of RNA polymerase mutations to the fitness cost of rifampin resistance in Pseudomonas aeruginosa
    • Qi, Q., Preston, G. M. & MacLean, R. C. Linking system-wide impacts of RNA polymerase mutations to the fitness cost of rifampin resistance in Pseudomonas aeruginosa. Mbio 5, e01562 (2014).
    • (2014) Mbio , vol.5 , pp. e01562
    • Qi, Q.1    Preston, G.M.2    MacLean, R.C.3
  • 48
    • 0025751624 scopus 로고
    • An improved Tn7-based system for the single-copy insertion of cloned genes into chromosomes of gram-negative bacteria
    • Bao, Y., Lies, D. P., Fu, H. & Roberts, G. P. An improved Tn7-based system for the single-copy insertion of cloned genes into chromosomes of gram-negative bacteria. Gene 109, 167-168 (1991).
    • (1991) Gene , vol.109 , pp. 167-168
    • Bao, Y.1    Lies, D.P.2    Fu, H.3    Roberts, G.P.4
  • 49
    • 48449104617 scopus 로고    scopus 로고
    • GOEAST: A web-based software toolkit for Gene Ontology enrichment analysis
    • Zheng, Q. & Wang, X. J. GOEAST: a web-based software toolkit for Gene Ontology enrichment analysis. Nucleic Acids Res. 36, W358-W363 (2008).
    • (2008) Nucleic Acids Res. , vol.36 , pp. W358-W363
    • Zheng, Q.1    Wang, X.J.2
  • 50
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for Annotation Visualization and Integrated Discovery
    • Dennis, G. et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 4, P3, 2003).
    • (2003) Genome Biol. , vol.4 , pp. P3
    • Dennis, G.1
  • 51
    • 78651267246 scopus 로고    scopus 로고
    • Pseudomonas Genome Database: Improved comparative analysis and population genomics capability for Pseudomonas genomes
    • Winsor, G. L. et al. Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes. Nucleic Acids Res. 39, D596-D600 (2011).
    • (2011) Nucleic Acids Res. , vol.39 , pp. D596-D600
    • Winsor, G.L.1
  • 52
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
    • Altschul, S. F. et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25, 3389-3402 (1997).
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3389-3402
    • Altschul, S.F.1
  • 53
    • 78651301328 scopus 로고    scopus 로고
    • Collaboration INSD. the sequence read archive
    • Leinonen, R., Sugawara, H. & Shumway, M. Collaboration INSD. The sequence read archive. Nucleic Acids Res. 39, D19-D21 (2011).
    • (2011) Nucleic Acids Res. , vol.39 , pp. D19-D21
    • Leinonen, R.1    Sugawara, H.2    Shumway, M.3


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