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Volumn 35, Issue 6, 2015, Pages 1747-1754

Effect of zinc on high glucose-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells

Author keywords

Epithelial to mesenchymal transition; High glucose; Renal tubular epithelial cells; Zinc

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; GLUCOSE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N,N,N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN; ZINC;

EID: 84928386773     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2170     Document Type: Article
Times cited : (37)

References (46)
  • 1
    • 20844432671 scopus 로고    scopus 로고
    • Pathogenetic mechanisms of diabetic nephropathy
    • Schena FP and Gesualdo L: Pathogenetic mechanisms of diabetic nephropathy. J Am Soc Nephrol 16 (Suppl 1): S30-S33, 2005
    • (2005) J Am Soc Nephrol , vol.16 , pp. S30-S33
    • Schena, F.P.1    Gesualdo, L.2
  • 2
    • 77958157740 scopus 로고    scopus 로고
    • Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Chinese type 2 diabetic patients: Comment on the study by Liu et al
    • Lapice E, Pinelli M, Riccardi G, et al: Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Chinese type 2 diabetic patients: comment on the study by Liu et al. Diabetes Care 33: e114, 2010
    • (2010) Diabetes Care , vol.33 , pp. e114
    • Lapice, E.1    Pinelli, M.2    Riccardi, G.3
  • 3
    • 8344244535 scopus 로고    scopus 로고
    • Diabetic nephropathy-A review of the natural history, burden, risk factors and treatment
    • Ayodele OE, Alebiosu CO and Salako BL: Diabetic nephropathy-A review of the natural history, burden, risk factors and treatment. J Natl Med Assoc 96: 1445-1454, 2004
    • (2004) J Natl Med Assoc , vol.96 , pp. 1445-1454
    • Ayodele, O.E.1    Alebiosu, C.O.2    Salako, B.L.3
  • 4
    • 80053503728 scopus 로고    scopus 로고
    • Role of bone morphogenetic proteins-7 (BMP-7) in the renal improvement effect of DangGui (Angelica sinensis) in type-1 diabetic rats
    • Yeh CH, Chang CK, Cheng KC, et al: Role of bone morphogenetic proteins-7 (BMP-7) in the renal improvement effect of DangGui (Angelica sinensis) in type-1 diabetic rats. Evid Based Complement Alternat Med 2011: 796723, 2011
    • (2011) Evid Based Complement Alternat Med , vol.2011 , pp. 796723
    • Yeh, C.H.1    Chang, C.K.2    Cheng, K.C.3
  • 6
    • 34247533369 scopus 로고    scopus 로고
    • Phenotypic transitions and fibrosis in diabetic nephropathy
    • Simonson MS: Phenotypic transitions and fibrosis in diabetic nephropathy. Kidney Int 71: 846-854, 2007
    • (2007) Kidney Int , vol.71 , pp. 846-854
    • Simonson, M.S.1
  • 7
    • 33748031093 scopus 로고    scopus 로고
    • Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: Implications for diabetic renal disease
    • Burns WC, Twigg SM, Forbes JM, et al: Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease. J Am Soc Nephrol 17: 2484-2494, 2006
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2484-2494
    • Burns, W.C.1    Twigg, S.M.2    Forbes, J.M.3
  • 8
    • 79960901978 scopus 로고    scopus 로고
    • The role of the p38 MAPK signaling pathway in high glucose-induced epithelial-mesenchymal transition of cultured human renal tubular epithelial cells
    • Lv ZM, Wang Q, Wan Q, et al: The role of the p38 MAPK signaling pathway in high glucose-induced epithelial-mesenchymal transition of cultured human renal tubular epithelial cells. PLoS One 6: e22806, 2011
    • (2011) PLoS One , vol.6 , pp. e22806
    • Lv, Z.M.1    Wang, Q.2    Wan, Q.3
  • 9
    • 77951528072 scopus 로고    scopus 로고
    • Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3beta, Snail1, and beta-catenin in renal proximal tubule cells
    • Lee YJ and Han HJ: Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3beta, Snail1, and beta-catenin in renal proximal tubule cells. Am J Physiol Renal Physiol 298: F1263-F1275, 2009
    • (2009) Am J Physiol Renal Physiol , vol.298 , pp. F1263-F1275
    • Lee, Y.J.1    Han, H.J.2
  • 10
    • 84872425476 scopus 로고    scopus 로고
    • Alterations in kidney tissue following zinc supplementation to STZ-induced diabetic rats
    • Karatug A, Kaptan E, Bolkent S, et al: Alterations in kidney tissue following zinc supplementation to STZ-induced diabetic rats. J Trace Elem Med Biol 27: 52-57, 2012
    • (2012) J Trace Elem Med Biol , vol.27 , pp. 52-57
    • Karatug, A.1    Kaptan, E.2    Bolkent, S.3
  • 11
    • 73949157960 scopus 로고    scopus 로고
    • The effects of chromium histidinate on mineral status of serum and tissue in fat-fed and streptozotocin-treated type II diabetic rats
    • Dogukan A, Sahin N, Tuzcu M, et al: The effects of chromium histidinate on mineral status of serum and tissue in fat-fed and streptozotocin-treated type II diabetic rats. Biol Trace Elem Res 131: 124-132, 2009
    • (2009) Biol Trace Elem Res , vol.131 , pp. 124-132
    • Dogukan, A.1    Sahin, N.2    Tuzcu, M.3
  • 13
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • Kalluri R and Neilson EG: Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 1776-1784, 2003
    • (2003) J Clin Invest , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 14
    • 1642379154 scopus 로고    scopus 로고
    • The role of epithelial-to-mesenchymal transition in renal fibrosis
    • (Berl)
    • Zeisberg M and Kalluri R: The role of epithelial-to-mesenchymal transition in renal fibrosis. J Mol Med (Berl) 82: 175-181, 2004
    • (2004) J Mol Med , vol.82 , pp. 175-181
    • Zeisberg, M.1    Kalluri, R.2
  • 15
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • Sato M, Muragaki Y, Saika S, et al: Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112: 1486-1494, 2003
    • (2003) J Clin Invest , vol.112 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3
  • 16
    • 70350545853 scopus 로고    scopus 로고
    • TGF-beta1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy
    • Hills CE and Squires PE: TGF-beta1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy. Am J Nephrol 31: 68-74, 2010
    • (2010) Am J Nephrol , vol.31 , pp. 68-74
    • Hills, C.E.1    Squires, P.E.2
  • 17
    • 42449150792 scopus 로고    scopus 로고
    • Intracellular signalling by C-peptide
    • 2008
    • Hills CE and Brunskill NJ: Intracellular signalling by C-peptide. Exp Diabetes Res 2008: 635158, 2008
    • (2008) Exp Diabetes Res , pp. 635158
    • Hills, C.E.1    Brunskill, N.J.2
  • 18
    • 34250362384 scopus 로고    scopus 로고
    • Possible inhibitory effect of oral zinc supplementation on hepatic fibrosis through downregulation of TIMP-1: A pilot study
    • Takahashi M, Saito H, Higashimoto M, et al: Possible inhibitory effect of oral zinc supplementation on hepatic fibrosis through downregulation of TIMP-1: a pilot study. Hepatol Res 37: 405-409, 2007
    • (2007) Hepatol Res , vol.37 , pp. 405-409
    • Takahashi, M.1    Saito, H.2    Higashimoto, M.3
  • 19
    • 85047692717 scopus 로고    scopus 로고
    • Alcohol-induced myocardial fibrosis in metallothionein-null mice: Prevention by zinc supple-mentation
    • Wang L, Zhou Z, Saari JT, et al: Alcohol-induced myocardial fibrosis in metallothionein-null mice: prevention by zinc supplementation. Am J Pathol 167: 337-344, 2005
    • (2005) Am J Pathol , vol.167 , pp. 337-344
    • Wang, L.1    Zhou, Z.2    Saari, J.T.3
  • 20
    • 58149218447 scopus 로고    scopus 로고
    • Causes and consequences of zinc dyshomeostasis in rats with chronic aldosteronism
    • Gandhi MS, Deshmukh PA, Kamalov G, et al: Causes and consequences of zinc dyshomeostasis in rats with chronic aldosteronism. J Cardiovasc Pharmacol 52: 245-252, 2008
    • (2008) J Cardiovasc Pharmacol , vol.52 , pp. 245-252
    • Gandhi, M.S.1    Deshmukh, P.A.2    Kamalov, G.3
  • 22
    • 84870699469 scopus 로고    scopus 로고
    • Zinc inhibits high glucose-induced apoptosis in peritoneal mesothelial cells
    • Zhang X, Liang D, Guo B, et al: Zinc inhibits high glucose-induced apoptosis in peritoneal mesothelial cells. Biol Trace Elem Res 150: 424-432, 2012
    • (2012) Biol Trace Elem Res , vol.150 , pp. 424-432
    • Zhang, X.1    Liang, D.2    Guo, B.3
  • 23
    • 0020974044 scopus 로고
    • In vitro approaches for determining mechanisms of toxicity and carcinogenicity by asbestos in the gastrointestinal and respiratory tracts
    • Mossman BT: In vitro approaches for determining mechanisms of toxicity and carcinogenicity by asbestos in the gastrointestinal and respiratory tracts. Environ Health Perspect 53: 155-161, 1983
    • (1983) Environ Health Perspect , vol.53 , pp. 155-161
    • Mossman, B.T.1
  • 24
    • 20544437490 scopus 로고    scopus 로고
    • Role of reactive oxygen species in TGF-beta1-induced mitogen-Activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells
    • Rhyu DY, Yang Y, Ha H, et al: Role of reactive oxygen species in TGF-beta1-induced mitogen-Activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol 16: 667-675, 2005
    • (2005) J Am Soc Nephrol , vol.16 , pp. 667-675
    • Rhyu, D.Y.1    Yang, Y.2    Ha, H.3
  • 25
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang J and Liu Y: Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 159: 1465-1475, 2001
    • (2001) Am J Pathol , vol.159 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 26
    • 0042366348 scopus 로고    scopus 로고
    • Reactive oxygen species and matrix remodeling in diabetic kidney
    • Ha H and Lee HB: Reactive oxygen species and matrix remodeling in diabetic kidney. J Am Soc Nephrol 14: S246-S249, 2003
    • (2003) J Am Soc Nephrol , vol.14 , pp. S246-S249
    • Ha, H.1    Lee, H.B.2
  • 27
    • 39049128068 scopus 로고    scopus 로고
    • Biliverdin reductase mediates hypoxia-induced EMT via PI3-kinase and Akt
    • Zeng R, Yao Y, Han M, et al: Biliverdin reductase mediates hypoxia-induced EMT via PI3-kinase and Akt. J Am Soc Nephrol 19: 380-387, 2008
    • (2008) J Am Soc Nephrol , vol.19 , pp. 380-387
    • Zeng, R.1    Yao, Y.2    Han, M.3
  • 28
    • 34948834648 scopus 로고    scopus 로고
    • Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion
    • Boca M, D'Amato L, Distefano G, et al: Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion. Mol Biol Cell 18: 4050-4061, 2007
    • (2007) Mol Biol Cell , vol.18 , pp. 4050-4061
    • Boca, M.1    D'Amato, L.2    Distefano, G.3
  • 29
    • 48749112189 scopus 로고    scopus 로고
    • Transforming growth factor {beta}1 induces epithelial-mesenchymal transition by activating the JNK-Smad3 pathway in rat peritoneal mesothelial cells
    • Liu Q, Mao H, Nie J, et al: Transforming growth factor {beta}1 induces epithelial-mesenchymal transition by activating the JNK-Smad3 pathway in rat peritoneal mesothelial cells. Perit Dial Int 28 (Suppl 3): S88-S95, 2008
    • (2008) Perit Dial Int 28 (Suppl 3) , pp. S88-S95
    • Liu, Q.1    Mao, H.2    Nie, J.3
  • 30
    • 70349659185 scopus 로고    scopus 로고
    • Angiotensin II induces connective tissue growth factor and collagen i expression via transforming growth factor-beta-dependent and-independent Smad pathways: The role of Smad3
    • Yang F, Chung AC, Huang XR, et al: Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and-independent Smad pathways: the role of Smad3. Hypertension 54: 877-884, 2009
    • (2009) Hypertension , vol.54 , pp. 877-884
    • Yang, F.1    Chung, A.C.2    Huang, X.R.3
  • 31
    • 52049111663 scopus 로고    scopus 로고
    • TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta
    • Yamashita M, Fatyol K, Jin C, et al: TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta. Mol Cell 31: 918-924, 2008
    • (2008) Mol Cell , vol.31 , pp. 918-924
    • Yamashita, M.1    Fatyol, K.2    Jin, C.3
  • 32
    • 35748954915 scopus 로고    scopus 로고
    • Zinc-dependent suppression of TNF-Alpha production is mediated by protein kinase A-induced inhibition of Raf-1, i kappa B kinase beta, and NF-kappa B
    • von Bulow V, Dubben S, Engelhardt G, et al: Zinc-dependent suppression of TNF-Alpha production is mediated by protein kinase A-induced inhibition of Raf-1, I kappa B kinase beta, and NF-kappa B. J Immunol 179: 4180-4186, 2007
    • (2007) J Immunol , vol.179 , pp. 4180-4186
    • Von Bulow, V.1    Dubben, S.2    Engelhardt, G.3
  • 33
    • 33845415089 scopus 로고    scopus 로고
    • Zinc modulates cytokine-induced lung epithelial cell barrier permeability
    • Bao S and Knoell DL: Zinc modulates cytokine-induced lung epithelial cell barrier permeability. Am J Physiol Lung Cell Mol Physiol 291: L1132-L1141, 2006
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291 , pp. L1132-L1141
    • Bao, S.1    Knoell, D.L.2
  • 34
    • 0032720129 scopus 로고    scopus 로고
    • Bifidobacterium animalis protects intestine from damage induced by zinc deficiency in rats
    • Mengheri E, Nobili F, Vignolini F, et al: Bifidobacterium animalis protects intestine from damage induced by zinc deficiency in rats. J Nutr 129: 2251-2257, 1999
    • (1999) J Nutr , vol.129 , pp. 2251-2257
    • Mengheri, E.1    Nobili, F.2    Vignolini, F.3
  • 35
    • 77955664627 scopus 로고    scopus 로고
    • AMP-Activated protein kinase is required for induction of apoptosis and epithelial-to-mesen-chymal transition
    • Wang X, Pan X and Song J: AMP-Activated protein kinase is required for induction of apoptosis and epithelial-to-mesenchymal transition. Cell Signal 22: 1790-1797, 2010
    • (2010) Cell Signal , vol.22 , pp. 1790-1797
    • Wang, X.1    Pan, X.2    Song, J.3
  • 36
    • 0037229290 scopus 로고    scopus 로고
    • Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells
    • Lan HY: Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells. Curr Opin Nephrol Hypertens 12: 25-29, 2003
    • (2003) Curr Opin Nephrol Hypertens , vol.12 , pp. 25-29
    • Lan, H.Y.1
  • 37
    • 53149083386 scopus 로고    scopus 로고
    • Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms
    • Corniola RS, Tassabehji NM, Hare J, et al: Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms. Brain Res 1237: 52-61, 2008
    • (2008) Brain Res , vol.1237 , pp. 52-61
    • Corniola, R.S.1    Tassabehji, N.M.2    Hare, J.3
  • 38
    • 0028866179 scopus 로고
    • Differential effects of transforming growth factor-beta on osteoclast-like cell formation in mouse marrow culture: Relation to the effect of zinc-chelating dipeptides
    • Yamaguchi M and Kishi S: Differential effects of transforming growth factor-beta on osteoclast-like cell formation in mouse marrow culture: relation to the effect of zinc-chelating dipeptides. Peptides 16: 1483-1488, 1995
    • (1995) Peptides , vol.16 , pp. 1483-1488
    • Yamaguchi, M.1    Kishi, S.2
  • 39
    • 65749117033 scopus 로고    scopus 로고
    • Zinc supplementation attenuates ethanol-And acetaldehyde-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS) production and by influencing intracellular signaling
    • Szuster-Ciesielska A, Plewka K, Daniluk J, et al: Zinc supplementation attenuates ethanol-And acetaldehyde-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS) production and by influencing intracellular signaling. Biochem Pharmacol 78: 301-314, 2009
    • (2009) Biochem Pharmacol , vol.78 , pp. 301-314
    • Szuster-Ciesielska, A.1    Plewka, K.2    Daniluk, J.3
  • 40
    • 42149155984 scopus 로고    scopus 로고
    • Clinical, immunological, anti-inflammatory and antioxidant roles of zinc
    • Prasad AS: Clinical, immunological, anti-inflammatory and antioxidant roles of zinc. Exp Gerontol 43: 370-377, 2008
    • (2008) Exp Gerontol , vol.43 , pp. 370-377
    • Prasad, A.S.1
  • 41
    • 0037168653 scopus 로고    scopus 로고
    • Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line
    • Ho E and Ames BN: Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line. Proc Natl Acad Sci USA 99: 16770-16775, 2002
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16770-16775
    • Ho, E.1    Ames, B.N.2
  • 42
    • 84873605535 scopus 로고    scopus 로고
    • Zinc transporter 5 and zinc transporter 7 induced by high glucose protects peritoneal mesothelial cells from undergoing apoptosis
    • Zhang X, Liang D, Guo B, et al: Zinc transporter 5 and zinc transporter 7 induced by high glucose protects peritoneal mesothelial cells from undergoing apoptosis. Cell Signal 25: 999-1010, 2013
    • (2013) Cell Signal , vol.25 , pp. 999-1010
    • Zhang, X.1    Liang, D.2    Guo, B.3
  • 43
    • 84856657290 scopus 로고    scopus 로고
    • Midkine and the kidney: Health and diseases
    • Kosugi T and Sato W: Midkine and the kidney: health and diseases. Nephrol Dial Transplant 27: 16-21, 2012
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 16-21
    • Kosugi, T.1    Sato, W.2
  • 44
    • 84878904455 scopus 로고    scopus 로고
    • Cell survival and metastasis regulation by Akt signaling in colorectal cancer
    • Agarwal E, Brattain MG and Chowdhury S: Cell survival and metastasis regulation by Akt signaling in colorectal cancer. Cell Signal 25: 1711-1719, 2013
    • (2013) Cell Signal , vol.25 , pp. 1711-1719
    • Agarwal, E.1    Brattain, M.G.2    Chowdhury, S.3
  • 45
    • 49949114895 scopus 로고    scopus 로고
    • Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo
    • Kattla JJ, Carew RM, Heljic M, et al: Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo. Am J Physiol Renal Physiol 295: 215-225, 2008
    • (2008) Am J Physiol Renal Physiol , vol.295 , pp. 215-225
    • Kattla, J.J.1    Carew, R.M.2    Heljic, M.3
  • 46
    • 84859954194 scopus 로고    scopus 로고
    • C-Jun-N-terminal kinase signaling is involved in cyclosporine-induced epithelial phenotypic changes
    • 2012
    • Pallet N, Thervet E and Anglicheau D: c-Jun-N-terminal kinase signaling is involved in cyclosporine-induced epithelial phenotypic changes. J Transplant 2012: 348604, 2012.
    • (2012) J Transplant , pp. 348604
    • Pallet, N.1    Thervet, E.2    Anglicheau, D.3


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