Zinc-dependent suppression of TNF-α production is mediated by protein kinase A-induced inhibition of Raf-1, IκB kinase β, and NF-κB

Journal of Immunology

Volumn 179, Issue 6, 2007, Pages 4180-4186

  Von Bülow, Verena ^a   Dubben, Svenja ^a   Engelhardt, Gabriela ^a   Hebel, Silke ^a   Plümäkers, Birgit ^a   Heine, Holger ^b   Rink, Lothar ^a   Haase, Hajo ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b Tuberculosis Center Borstel   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; RAF PROTEIN; SERINE; TUMOR NECROSIS FACTOR ALPHA; ZINC ION; DIVALENT CATION; I KAPPA B KINASE; PROTEIN KINASE INHIBITOR; ZINC;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL LINE; DOWN REGULATION; DRUG ANTAGONISM; IMMUNOLOGY; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CATIONS, DIVALENT; CELL LINE; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC GMP; DOWN-REGULATION; ENZYME ACTIVATION; HUMANS; I-KAPPA B KINASE; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; NF-KAPPA B; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-RAF; TUMOR NECROSIS FACTOR-ALPHA; ZINC;

EID: 35748954915     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.179.6.4180     Document Type: Article

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