Low molecular weight chitosan-insulin polyelectrolyte complex: Characterization and stability studies

Marine Drugs

Volumn 13, Issue 4, 2015, Pages 1765-1784

  Al Kurdi, Zakieh I ^a   Chowdhry, Babur Z ^b   Leharne, Stephen A ^b   Al Omari, Mahmoud M H ^a   Badwan, Adnan A ^a  

^a JORDANIAN PHARMACEUTICAL MANUFACTURING COMPANY   (Jordan)

^b UNIVERSITY OF GREENWICH   (United Kingdom)

Author keywords

Insulin; Low molecular weight chitosan; Oligochitosan; Polyelectrolyte complex; Stability

Indexed keywords

CHITOSAN; GLUCOSE; INSULIN; POLYELECTROLYTE; ANTIDIABETIC AGENT; CHITIN; ELECTROLYTE; EXCIPIENT; INSULIN, DESAMIDO (A21)-; MICELLE; OLIGOCHITOSAN;

ANIMAL EXPERIMENT; ARTICLE; DIABETES MELLITUS; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; GLUCOSE BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; NONHUMAN; PARTICLE SIZE; PH; POWDER; RAT; STOMACH PH; ZETA POTENTIAL; ANALOGS AND DERIVATIVES; ANIMAL; BIOAVAILABILITY; BIOTRANSFORMATION; BLOOD; CHEMISTRY; COMPARATIVE STUDY; DIABETES MELLITUS, EXPERIMENTAL; DRUG STORAGE; HYPERGLYCEMIA; METABOLISM; MICELLE; MOLECULAR WEIGHT; ORAL DRUG ADMINISTRATION; RANDOMIZATION; SPRAGUE DAWLEY RAT;

RATTUS;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; BIOTRANSFORMATION; CHITIN; DIABETES MELLITUS, EXPERIMENTAL; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; DRUG STABILITY; DRUG STORAGE; ELECTROLYTES; EXCIPIENTS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MICELLES; MOLECULAR WEIGHT; PARTICLE SIZE; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY;

EID: 84928380413     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md13041765     Document Type: Article

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