Personalized genomic analyses for cancer mutation discovery and interpretation

Science Translational Medicine

Volumn 7, Issue 283, 2015, Pages

  Jones, Siän ^a   Anagnostou, Valsamo ^b   Lytle, Karli ^a   Parpart Li, Sonya ^a   Nesselbush, Monica ^a   Riley, David R ^a   Shukla, Manish ^a   Chesnick, Bryan ^a   Kadan, Maura ^a   Papp, Eniko ^b   Galens, Kevin G ^a   Murphy, Derek ^a   Zhang, Theresa ^a   Kann, Lisa ^a   Sausen, Mark ^a   Angiuoli, Samuel V ^a   Diaz, Luis A ^b   Velculescu, Victor E ^b  

^a Personal Genome Diagnostics   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ACCURACY; ARTICLE; BIOINFORMATICS; CANCER GENETICS; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA DETERMINATION; EXOME; FALSE POSITIVE RESULT; GENE MUTATION; GENE TARGETING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GERMLINE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MUTATIONAL ANALYSIS; NEXT GENERATION SEQUENCING; ONCOGENE; PERSONALIZED MEDICINE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; TISSUE SPECIFICITY; BIOLOGY; DNA MUTATIONAL ANALYSIS; GENE LIBRARY; GENETIC PREDISPOSITION; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; MUTATION; NEOPLASM;

COMPUTATIONAL BIOLOGY; DNA MUTATIONAL ANALYSIS; EXOME; FALSE POSITIVE REACTIONS; GENE LIBRARY; GENETIC PREDISPOSITION TO DISEASE; GENOMICS; GERM-LINE MUTATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MUTATION; NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; PRECISION MEDICINE; RETROSPECTIVE STUDIES;

EID: 84928248330     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa7161     Document Type: Article

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