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Volumn 67, Issue 9, 2014, Pages 751-757

RAS testing of colorectal carcinoma - A guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Group

Author keywords

[No Author keywords available]

Indexed keywords

CETUXIMAB; DNA; PANITUMUMAB; GUANOSINE TRIPHOSPHATASE; KRAS PROTEIN, HUMAN; MEMBRANE PROTEIN; NRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN; TUMOR MARKER;

EID: 84921946952     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jclinpath-2014-202467     Document Type: Article
Times cited : (69)

References (40)
  • 1
    • 84940248419 scopus 로고    scopus 로고
    • cited 2014 12 May
    • CancerResearchUK. [cited 2014 12 May]. http://www.cancerresearchuk.org/ cancer-info/cancerstats/types/bowel/
  • 2
    • 84940276548 scopus 로고    scopus 로고
    • RCSEng, HSCIC. [cited 2014 12 May]
    • ACPGBI, RCSEng, HSCIC. National Bowel Cancer Audit Annual Report 2013 [cited 2014 12 May]. 29-38 http://www.acpgbi.org.uk/members/groups/nbocap/
    • (2013) National Bowel Cancer Audit Annual Report , pp. 29-38
  • 3
    • 0031471783 scopus 로고    scopus 로고
    • The pattern of recurrent colorectal cancer in a prospective randomised study and the characteristics of diagnostic tests
    • DOI 10.1007/s003840050118
    • Kjeldsen BJ, Kronborg O, Fenger C, et al. The pattern of recurrent colorectal cancer in a prospective randomised study and the characteristics of diagnostic tests. Int J Colorectal Dis 1997;12:329-34. (Pubitemid 28017718)
    • (1997) International Journal of Colorectal Disease , vol.12 , Issue.6 , pp. 329-334
    • Kjeldsen, B.J.1    Kronborg, O.2    Fenger, C.3    Jorgensen, O.D.4
  • 4
    • 79956310674 scopus 로고    scopus 로고
    • Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: The OPUS study
    • Bokemeyer C, Bondarenko I, Hartmann JT, et al. Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. Ann Oncol 2011;22:1535-46.
    • (2011) Ann Oncol , vol.22 , pp. 1535-1546
    • Bokemeyer, C.1    Bondarenko, I.2    Hartmann, J.T.3
  • 5
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • Van Cutsem E, Kohne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009;360:1408-17.
    • (2009) N Engl J Med , vol.360 , pp. 1408-1417
    • Van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 8
    • 84871273318 scopus 로고    scopus 로고
    • Guidelines for biomarker testing in colorectal carcinoma (CRC): A national consensus of the Spanish Society of Pathology (SEAP) and the Spanish Society of Medical Oncology (SEOM)
    • Garcia-Alfonso P, Salazar R, Garcia-Foncillas J, et al. Guidelines for biomarker testing in colorectal carcinoma (CRC): a national consensus of the Spanish Society of Pathology (SEAP) and the Spanish Society of Medical Oncology (SEOM). Clin Transl Oncol 2012;14:726-39.
    • (2012) Clin Transl Oncol , vol.14 , pp. 726-739
    • Garcia-Alfonso, P.1    Salazar, R.2    Garcia-Foncillas, J.3
  • 9
    • 84863401420 scopus 로고    scopus 로고
    • Validation of KRAS testing for anti-EGFR therapeutic decisions for patients with metastatic colorectal carcinoma
    • Molecular Oncology Resource Committee of the College of American P
    • Kamel-Reid S, Zhang T, Persons DL, et al. Molecular Oncology Resource Committee of the College of American P. Validation of KRAS testing for anti-EGFR therapeutic decisions for patients with metastatic colorectal carcinoma. Arch Pathol Lab Med 2012;136:26-32.
    • (2012) Arch Pathol Lab Med , vol.136 , pp. 26-32
    • Kamel-Reid, S.1    Zhang, T.2    Persons, D.L.3
  • 10
    • 83755174239 scopus 로고    scopus 로고
    • KRAS mutations testing in colorectal carcinoma patients in Italy: From guidelines to external quality assessment
    • Normanno N, Pinto C, Castiglione F, et al. KRAS mutations testing in colorectal carcinoma patients in Italy: from guidelines to external quality assessment. PloS One 2011;6:e29146.
    • (2011) PloS One , vol.6
    • Normanno, N.1    Pinto, C.2    Castiglione, F.3
  • 11
    • 84870717009 scopus 로고    scopus 로고
    • Concordant KRAS mutations in primary and metastatic colorectal cancer tissue specimens: A meta-analysis and systematic review
    • Han CB, Li F, Ma JT, et al. Concordant KRAS mutations in primary and metastatic colorectal cancer tissue specimens: a meta-analysis and systematic review. Cancer Invest 2012;30:741-7.
    • (2012) Cancer Invest , vol.30 , pp. 741-747
    • Han, C.B.1    Li, F.2    Ma, J.T.3
  • 12
    • 84864659128 scopus 로고    scopus 로고
    • Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer
    • Kim MJ, Lee HS, Kim JH, et al. Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer. BMC cancer 2012;12:347.
    • (2012) BMC Cancer , vol.12 , pp. 347
    • Kim, M.J.1    Lee, H.S.2    Kim, J.H.3
  • 13
    • 81355161673 scopus 로고    scopus 로고
    • KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma
    • Pang NK, Nga ME, Chin SY, et al. KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma. Cytopathology 2011;22:358-64.
    • (2011) Cytopathology , vol.22 , pp. 358-364
    • Pang, N.K.1    Nga, M.E.2    Chin, S.Y.3
  • 14
    • 0033400418 scopus 로고    scopus 로고
    • Genetic pathways in colorectal and other cancers
    • DOI 10.1016/S0959-8049(99)00298-1, PII S0959804999002981
    • Ilyas M, Straub J, Tomlinson IP, et al. Genetic pathways in colorectal and other cancers. Eur J Cancer 1999;35:1986-2002. (Pubitemid 30026220)
    • (1999) European Journal of Cancer , vol.35 , Issue.14 , pp. 1986-2002
    • Ilyas, M.1    Straub, J.2    Tomlinson, I.P.M.3    Bodmer, W.F.4
  • 15
    • 84870393673 scopus 로고    scopus 로고
    • The utility of diagnostic biopsy specimens for predictive molecular testing in colorectal cancer
    • Fadhil W, Ibrahem S, Seth R, et al. The utility of diagnostic biopsy specimens for predictive molecular testing in colorectal cancer. Histopathology 2012;61:1117-24.
    • (2012) Histopathology , vol.61 , pp. 1117-1124
    • Fadhil, W.1    Ibrahem, S.2    Seth, R.3
  • 16
    • 79960798099 scopus 로고    scopus 로고
    • Intra-tumoral heterogeneity of KRAS and BRAF mutation status in patients with advanced colorectal cancer (aCRC) and cost-effectiveness of multiple sample testing
    • Richman SD, Chambers P, Seymour MT, et al. Intra-tumoral heterogeneity of KRAS and BRAF mutation status in patients with advanced colorectal cancer (aCRC) and cost-effectiveness of multiple sample testing. Anal Cell Pathol 2011;34:61-6.
    • (2011) Anal Cell Pathol , vol.34 , pp. 61-66
    • Richman, S.D.1    Chambers, P.2    Seymour, M.T.3
  • 17
    • 76049098292 scopus 로고    scopus 로고
    • Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases
    • Baldus SE, Schaefer KL, Engers R, et al. Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases. Clin Cancer Res 2010;16:790-9.
    • (2010) Clin Cancer Res , vol.16 , pp. 790-799
    • Baldus, S.E.1    Schaefer, K.L.2    Engers, R.3
  • 18
    • 79955521656 scopus 로고    scopus 로고
    • Dynamics of cancer cell subpopulations in primary and metastatic colorectal tumors
    • Goranova TE, Ohue M, Shimoharu Y, et al. Dynamics of cancer cell subpopulations in primary and metastatic colorectal tumors. Clin Exp Metastasis 2011;28:427-35.
    • (2011) Clin Exp Metastasis , vol.28 , pp. 427-435
    • Goranova, T.E.1    Ohue, M.2    Shimoharu, Y.3
  • 19
    • 79960839494 scopus 로고    scopus 로고
    • KRAS mutations detected by the amplification refractory mutation system-Scorpion assays strongly correlate with therapeutic effect of cetuximab
    • Bando H, Yoshino T, Tsuchihara K, et al. KRAS mutations detected by the amplification refractory mutation system-Scorpion assays strongly correlate with therapeutic effect of cetuximab. Br J Cancer 2011;105:403-6.
    • (2011) Br J Cancer , vol.105 , pp. 403-406
    • Bando, H.1    Yoshino, T.2    Tsuchihara, K.3
  • 20
    • 79960435101 scopus 로고    scopus 로고
    • Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer
    • Molinari F, Felicioni L, Buscarino M, et al. Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer. Clin Cancer Res 2011;17:4901-14.
    • (2011) Clin Cancer Res , vol.17 , pp. 4901-4914
    • Molinari, F.1    Felicioni, L.2    Buscarino, M.3
  • 21
    • 84873509424 scopus 로고    scopus 로고
    • Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: Implications for treatment of metastatic colorectal cancer
    • Dono M, Massucco C, Chiara S, et al. Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: implications for treatment of metastatic colorectal cancer. Mol Med 2012;18:1519-26.
    • (2012) Mol Med , vol.18 , pp. 1519-1526
    • Dono, M.1    Massucco, C.2    Chiara, S.3
  • 22
    • 79952771911 scopus 로고    scopus 로고
    • Should oncologists be aware in their clinical practice of KRAS molecular analysis?
    • author reply e8-9
    • Santini D, Galluzzo S, Gaeta L, et al. Should oncologists be aware in their clinical practice of KRAS molecular analysis? J Clin Oncol 2011;29:e206-7; author reply e8-9.
    • (2011) J Clin Oncol , vol.29
    • Santini, D.1    Galluzzo, S.2    Gaeta, L.3
  • 23
    • 84863000299 scopus 로고    scopus 로고
    • The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
    • Diaz LA Jr., Williams RT, Wu J, et al. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature 2012;486:537-40.
    • (2012) Nature , vol.486 , pp. 537-540
    • Diaz Jr., L.A.1    Williams, R.T.2    Wu, J.3
  • 24
    • 84862999938 scopus 로고    scopus 로고
    • Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
    • Misale S, Yaeger R, Hobor S, et al. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. Nature 2012;486:532-6.
    • (2012) Nature , vol.486 , pp. 532-536
    • Misale, S.1    Yaeger, R.2    Hobor, S.3
  • 25
    • 79960463308 scopus 로고    scopus 로고
    • Preparing pathology for personalized medicine: Possibilities for improvement of the pre-analytical phase
    • Groenen PJ, Blokx WA, Diepenbroek C, et al. Preparing pathology for personalized medicine: possibilities for improvement of the pre-analytical phase. Histopathology 2011;59:1-7.
    • (2011) Histopathology , vol.59 , pp. 1-7
    • Groenen, P.J.1    Blokx, W.A.2    Diepenbroek, C.3
  • 26
    • 0036898005 scopus 로고    scopus 로고
    • Effect of fixatives and tissue processing on the content and integrity of nucleic acids
    • Srinivasan M, Sedmak D, Jewell S. Effect of fixatives and tissue processing on the content and integrity of nucleic acids. Am J Pathol 2002;161:1961-71. (Pubitemid 35434840)
    • (2002) American Journal of Pathology , vol.161 , Issue.6 , pp. 1961-1971
    • Srinivasan, M.1    Sedmak, D.2    Jewell, S.3
  • 27
    • 0032755991 scopus 로고    scopus 로고
    • A high frequency of sequence alterations is due to formalin fixation of archival specimens
    • Williams C, Ponten F, Moberg C, et al. A high frequency of sequence alterations is due to formalin fixation of archival specimens. Am J Pathol 1999;155:1467-71.
    • (1999) Am J Pathol , vol.155 , pp. 1467-1471
    • Williams, C.1    Ponten, F.2    Moberg, C.3
  • 28
    • 55949096184 scopus 로고    scopus 로고
    • The effects of tissue fixation alternatives on DNA content: A study on normal colon tissue
    • Baloglu G, Haholu A, Kucukodaci Z, et al. The effects of tissue fixation alternatives on DNA content: a study on normal colon tissue. Appl Immunohistochem Mol Morphol 2008;16:485-92.
    • (2008) Appl Immunohistochem Mol Morphol , vol.16 , pp. 485-492
    • Baloglu, G.1    Haholu, A.2    Kucukodaci, Z.3
  • 29
    • 81755162834 scopus 로고    scopus 로고
    • Molecular genetics external quality assessment pilot scheme for KRAS analysis in metastatic colorectal cancer
    • Deans ZC, Tull J, Beighton G, et al. Molecular genetics external quality assessment pilot scheme for KRAS analysis in metastatic colorectal cancer. Genet Test Mole Biomarkers 2011;15:777-83.
    • (2011) Genet Test Mole Biomarkers , vol.15 , pp. 777-783
    • Deans, Z.C.1    Tull, J.2    Beighton, G.3
  • 30
    • 70350462904 scopus 로고    scopus 로고
    • A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting
    • Whitehall V, Tran K, Umapathy A, et al. A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting. J Mol Diagn 2009;11:543-52.
    • (2009) J Mol Diagn , vol.11 , pp. 543-552
    • Whitehall, V.1    Tran, K.2    Umapathy, A.3
  • 31
    • 84863723714 scopus 로고    scopus 로고
    • A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens
    • Gonzalez de Castro D, Angulo B, Gomez B, et al. A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens. Br J Cancer 2012;107:345-51.
    • (2012) Br J Cancer , vol.107 , pp. 345-351
    • Gonzalez De Castro, D.1    Angulo, B.2    Gomez, B.3
  • 32
    • 84876088853 scopus 로고    scopus 로고
    • Comparison of COBAS 4800 KRAS, TaqMan PCR and high resolution melting PCR assays for the detection of KRAS somatic mutations in formalin-fixed paraffin embedded colorectal carcinomas
    • Harle A, Busser B, Rouyer M, et al. Comparison of COBAS 4800 KRAS, TaqMan PCR and high resolution melting PCR assays for the detection of KRAS somatic mutations in formalin-fixed paraffin embedded colorectal carcinomas. Virchows Arch 2013;462:329-35.
    • (2013) Virchows Arch , vol.462 , pp. 329-335
    • Harle, A.1    Busser, B.2    Rouyer, M.3
  • 33
    • 84895060068 scopus 로고    scopus 로고
    • KRAS testing in metastatic colorectal carcinoma: Challenges, controversies, breakthroughs and beyond
    • Malapelle U, Carlomagno C, de Luca C, et al. KRAS testing in metastatic colorectal carcinoma: challenges, controversies, breakthroughs and beyond. J Clin Pathol 2014;67:1-9.
    • (2014) J Clin Pathol , vol.67 , pp. 1-9
    • Malapelle, U.1    Carlomagno, C.2    De Luca, C.3
  • 34
    • 84883680951 scopus 로고    scopus 로고
    • Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer
    • Douillard JY, Oliner KS, Siena S, et al. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 2013;369:1023-34.
    • (2013) N Engl J Med , vol.369 , pp. 1023-1034
    • Douillard, J.Y.1    Oliner, K.S.2    Siena, S.3
  • 37
    • 78549273639 scopus 로고    scopus 로고
    • A standardized framework for the validation and verification of clinical molecular genetic tests
    • Mattocks CJ, Morris MA, Matthijs G, et al. A standardized framework for the validation and verification of clinical molecular genetic tests. Eur J Hum Genet 2010;18:1276-88.
    • (2010) Eur J Hum Genet , vol.18 , pp. 1276-1288
    • Mattocks, C.J.1    Morris, M.A.2    Matthijs, G.3
  • 38
    • 84867605846 scopus 로고    scopus 로고
    • Hurdles and complexities of codon 13 KRAS mutations
    • Morelli MP, Kopetz S. Hurdles and complexities of codon 13 KRAS mutations. J Clin Oncol 2012;30:3565-7.
    • (2012) J Clin Oncol , vol.30 , pp. 3565-3567
    • Morelli, M.P.1    Kopetz, S.2
  • 39
    • 79958817037 scopus 로고    scopus 로고
    • Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer
    • Tran B, Kopetz S, Tie J, et al. Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer. Cancer 2011;117:4623-32.
    • (2011) Cancer , vol.117 , pp. 4623-4632
    • Tran, B.1    Kopetz, S.2    Tie, J.3
  • 40
    • 84898476658 scopus 로고    scopus 로고
    • Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA
    • Thierry AR, Mouliere F, El Messaoudi S, et al. Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA. Nat Med 2014;20:430-5.
    • (2014) Nat Med , vol.20 , pp. 430-435
    • Thierry, A.R.1    Mouliere, F.2    El Messaoudi, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.