Ixodes ricinus salivary serpin IRS-2 affects Th17 differentiation via inhibition of the interleukin-6/STAT-3 signaling pathway

Infection and Immunity

Volumn 83, Issue 5, 2015, Pages 1949-1956

  Páleníková, Jana ^a,b   Lieskovská, Jaroslava ^a,b   Langhansová, Helena ^a,b   Kotsyfakis, Michalis ^b   Chmelař, Jindřich ^a,c   Kopeckỳ, Jan ^a,b  

^a UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

^b INSTITUTE OF PARASITOLOGY   (Czech Republic)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 22; INTERLEUKIN 6; INTERLEUKIN 9; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; SALIVA PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; INTERLEUKIN-6, MOUSE; SERINE PROTEINASE INHIBITOR; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BORRELIA; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; GENE EXPRESSION; INNATE IMMUNITY; IXODES RICINUS; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SALIVARY GLAND; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TH17 CELL; TRANSCRIPTION INITIATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL DIFFERENTIATION; DRUG EFFECTS; IMMUNOLOGY; IXODES; METABOLISM; PHYSIOLOGY;

ANIMALS; BORRELIA; CELL DIFFERENTIATION; DENDRITIC CELLS; FEMALE; INTERLEUKIN-6; IXODES; MICE, INBRED C57BL; SERPINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TH17 CELLS;

EID: 84928174105     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.03065-14     Document Type: Article

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