Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus

FEBS Journal

Volumn 276, Issue 12, 2009, Pages 3235-3246

  Prevot, Pierre Paul ^a   Beschin, Alain ^b,c   Lins, Laurence ^d   Beaufays, Jérôme ^a   Grosjean, Amélie ^a,e   Bruys, Léa ^b,c   Adam, Benoît ^d   Brossard, Michel ^a,e   Brasseur, Robert ^d   Zouaoui Boudjeltia, Karim ^a,e   Vanhamme, Luc ^a   Godfroid, Edmond ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^d UNIVERSITY OF LIÈGE   (Belgium)

^e UNIVERSITY OF NEUCHÂTEL   (Switzerland)

Author keywords

Inflammatory; Receptor binding domain; Sepsis; Serpin; Tick

Indexed keywords

DEXAMETHASONE; IMMUNOSUPPRESSIVE AGENT; IMMUNOSUPPRESSIVE AGENT IRIS; PROTEINASE; SERINE PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; EXPERIMENTAL RABBIT; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IXODES RICINUS; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RAT; SALIVA; SEPTIC SHOCK;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; BINDING SITES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IXODES; LEUKOCYTE ELASTASE; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED STRAINS; MODELS, MOLECULAR; MONOCYTES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RABBITS; RECOMBINANT PROTEINS; SALIVA; SERPINS; SHOCK, SEPTIC; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

IXODES RICINUS; IXODIDA;

EID: 66249123921     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07038.x     Document Type: Article

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