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Volumn 26, Issue 5, 2015, Pages 540-546

Chlorogenic acid enhances the effects of 5-fluorouracil in human hepatocellular carcinoma cells through the inhibition of extracellular signal-regulated kinases

Author keywords

5 fluorouracil; chlorogenic acid; extracellular signal regulated kinases; reactive oxygen species; synergism

Indexed keywords

CHLOROGENIC ACID; FLUOROURACIL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC AGENT;

EID: 84928168609     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0000000000000218     Document Type: Article
Times cited : (69)

References (34)
  • 2
    • 79952039170 scopus 로고    scopus 로고
    • Evolving strategies for the management of intermediate-stage hepatocellular carcinoma: Available evidence and expert opinion on the use of transarterial chemoembolization
    • Raoul JL, Sangro B, Forner A, Mazzaferro V, Piscaglia F, Bolondi L, et al. Evolving strategies for the management of intermediate-stage hepatocellular carcinoma: available evidence and expert opinion on the use of transarterial chemoembolization. Cancer Treat Rev 2011; 37:212-220.
    • (2011) Cancer Treat Rev , vol.37 , pp. 212-220
    • Raoul, J.L.1    Sangro, B.2    Forner, A.3    Mazzaferro, V.4    Piscaglia, F.5    Bolondi, L.6
  • 3
    • 84869760183 scopus 로고    scopus 로고
    • Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma according to child-pugh classification
    • Miyaki D, Aikata H, Honda Y, Naeshiro N, Nakahara T, Tanaka M, et al. Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma according to Child-Pugh classification. J Gastroenterol Hepatol 2012; 27:1850-1857.
    • (2012) J Gastroenterol Hepatol , vol.27 , pp. 1850-1857
    • Miyaki, D.1    Aikata, H.2    Honda, Y.3    Naeshiro, N.4    Nakahara, T.5    Tanaka, M.6
  • 4
    • 84863952174 scopus 로고    scopus 로고
    • Efficacy of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma
    • Baek YH, Kim KT, Lee SW, Jeong JS, Park BH, Nam KJ, et al. Efficacy of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma. World J Gastroenterol 2012; 18:3426-3434.
    • (2012) World J Gastroenterol , vol.18 , pp. 3426-3434
    • Baek, Y.H.1    Kim, K.T.2    Lee, S.W.3    Jeong, J.S.4    Park, B.H.5    Nam, K.J.6
  • 5
    • 84897091535 scopus 로고    scopus 로고
    • Vasohibin 2 decreases the cisplatin sensitivity of hepatocarcinoma cell line by downregulating p53
    • Li Z, Tu M, Han B, Gu Y, Xue X, Sun J, et al. Vasohibin 2 decreases the cisplatin sensitivity of hepatocarcinoma cell line by downregulating p53. PLoS One 2014; 9:e90358.
    • (2014) PLoS One , vol.9 , pp. e90358
    • Li, Z.1    Tu, M.2    Han, B.3    Gu, Y.4    Xue, X.5    Sun, J.6
  • 6
    • 84880994920 scopus 로고    scopus 로고
    • Selenocystine potentiates cancer cell apoptosis induced by 5-fluorouracil by triggering reactive oxygen species-mediated dna damage and inactivation of the erk pathway
    • Fan C, Chen J, Wang Y, Wong YS, Zhang Y, Zheng W, et al. Selenocystine potentiates cancer cell apoptosis induced by 5-fluorouracil by triggering reactive oxygen species-mediated DNA damage and inactivation of the ERK pathway. Free Radic Biol Med 2013; 65:305-316.
    • (2013) Free Radic Biol Med , vol.65 , pp. 305-316
    • Fan, C.1    Chen, J.2    Wang, Y.3    Wong, Y.S.4    Zhang, Y.5    Zheng, W.6
  • 7
    • 84864745110 scopus 로고    scopus 로고
    • The coffee constituent chlorogenic acid induces cellular dna damage and formation of topoisomerase i-And ii-dna complexes in cells
    • Burgos-Moron E, Calderon-Montano JM, Orta ML, Pastor N, Perez-Guerrero C, Austin C, et al. The coffee constituent chlorogenic acid induces cellular DNA damage and formation of topoisomerase I-And II-DNA complexes in cells. J Agric Food Chem 2012; 60:7384-7391.
    • (2012) J Agric Food Chem , vol.60 , pp. 7384-7391
    • Burgos-Moron, E.1    Calderon-Montano, J.M.2    Orta, M.L.3    Pastor, N.4    Perez-Guerrero, C.5    Austin, C.6
  • 8
    • 84866324118 scopus 로고    scopus 로고
    • Protective effects of chlorogenic acid against ischemia/reperfusion injury in rat liver: Molecular evidence of its antioxidant and anti-inflammatory properties
    • Yun N, Kang JW, Lee SM. Protective effects of chlorogenic acid against ischemia/reperfusion injury in rat liver: molecular evidence of its antioxidant and anti-inflammatory properties. J Nutr Biochem 2012; 23:1249-1255.
    • (2012) J Nutr Biochem , vol.23 , pp. 1249-1255
    • Yun, N.1    Kang, J.W.2    Lee, S.M.3
  • 9
    • 84859590248 scopus 로고    scopus 로고
    • Antihypertensive effects and mechanisms of chlorogenic acids
    • Zhao Y, Wang J, Ballevre O, Luo H, Zhang W. Antihypertensive effects and mechanisms of chlorogenic acids. Hypertens Res 2012; 35:370-374.
    • (2012) Hypertens Res , vol.35 , pp. 370-374
    • Zhao, Y.1    Wang, J.2    Ballevre, O.3    Luo, H.4    Zhang, W.5
  • 10
    • 84878223917 scopus 로고    scopus 로고
    • Effect of chlorogenic acid on lps-induced proinflammatory signaling in hepatic stellate cells
    • Shi H, Dong L, Dang X, Liu Y, Jiang J, Wang Y, et al. Effect of chlorogenic acid on LPS-induced proinflammatory signaling in hepatic stellate cells. Inflamm Res 2013; 62:581-587.
    • (2013) Inflamm Res , vol.62 , pp. 581-587
    • Shi, H.1    Dong, L.2    Dang, X.3    Liu, Y.4    Jiang, J.5    Wang, Y.6
  • 11
    • 77956898289 scopus 로고    scopus 로고
    • Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice
    • Xu Y, Chen J, Yu X, Tao W, Jiang F, Yin Z, et al. Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice. Inflamm Res 2010; 59:871-877.
    • (2010) Inflamm Res , vol.59 , pp. 871-877
    • Xu, Y.1    Chen, J.2    Yu, X.3    Tao, W.4    Jiang, F.5    Yin, Z.6
  • 12
    • 84885771953 scopus 로고    scopus 로고
    • Chlorogenic acid, a dietary polyphenol, protects acetaminophen-induced liver injury and its mechanism
    • Ji L, Jiang P, Lu B, Sheng Y, Wang X, Wang Z. Chlorogenic acid, a dietary polyphenol, protects acetaminophen-induced liver injury and its mechanism. J Nutr Biochem 2013; 24:1911-1919.
    • (2013) J Nutr Biochem , vol.24 , pp. 1911-1919
    • Ji, L.1    Jiang, P.2    Lu, B.3    Sheng, Y.4    Wang, X.5    Wang, Z.6
  • 13
    • 70350185396 scopus 로고    scopus 로고
    • Chlorogenic acid against carbon tetrachloride-induced liver fibrosis in rats
    • Shi H, Dong L, Bai Y, Zhao J, Zhang Y, Zhang L. Chlorogenic acid against carbon tetrachloride-induced liver fibrosis in rats. Eur J Pharmacol 2009; 623:119-124.
    • (2009) Eur J Pharmacol , vol.623 , pp. 119-124
    • Shi, H.1    Dong, L.2    Bai, Y.3    Zhao, J.4    Zhang, Y.5    Zhang, L.6
  • 14
    • 84870689066 scopus 로고    scopus 로고
    • Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway
    • Shi H, Dong L, Jiang J, Zhao J, Zhao G, Dang X, et al. Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway. Toxicology 2013; 303:107-114.
    • (2013) Toxicology , vol.303 , pp. 107-114
    • Shi, H.1    Dong, L.2    Jiang, J.3    Zhao, J.4    Zhao, G.5    Dang, X.6
  • 15
    • 77951123183 scopus 로고    scopus 로고
    • Epidemiologic evidence on coffee and cancer
    • Arab L. Epidemiologic evidence on coffee and cancer. Nutr Cancer 2010; 62:271-283.
    • (2010) Nutr Cancer , vol.62 , pp. 271-283
    • Arab, L.1
  • 16
    • 67449100033 scopus 로고    scopus 로고
    • Effect of coffee and green tea consumption on the risk of liver cancer: Cohort analysis by hepatitis virus infection status
    • Inoue M, Kurahashi N, Iwasaki M, Shimazu T, Tanaka Y, Mizokami M, et al. Effect of coffee and green tea consumption on the risk of liver cancer: cohort analysis by hepatitis virus infection status. Cancer Epidemiol Biomarkers Prev 2009; 18:1746-1753.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 1746-1753
    • Inoue, M.1    Kurahashi, N.2    Iwasaki, M.3    Shimazu, T.4    Tanaka, Y.5    Mizokami, M.6
  • 17
    • 33750055230 scopus 로고    scopus 로고
    • Coffee consumption and reduced risk of hepatocellular carcinoma among patients with chronic type c liver disease: A case-control study
    • Ohfuji S, Fukushima W, Tanaka T, Habu D, Tamori A, Sakaguchi H, et al. Coffee consumption and reduced risk of hepatocellular carcinoma among patients with chronic type C liver disease: a case-control study. Hepatol Res 2006; 36:201-208.
    • (2006) Hepatol Res , vol.36 , pp. 201-208
    • Ohfuji, S.1    Fukushima, W.2    Tanaka, T.3    Habu, D.4    Tamori, A.5    Sakaguchi, H.6
  • 18
    • 34347370225 scopus 로고    scopus 로고
    • N-Acetyl-l-cysteine affords protection against lead-induced cytotoxicity and oxidative stress in human liver carcinoma (hepg2) cells
    • Yedjou CG, Tchounwou PB. N-Acetyl-l-cysteine affords protection against lead-induced cytotoxicity and oxidative stress in human liver carcinoma (HepG2) cells. Int J Environ Res Public Health 2007; 4:132-137.
    • (2007) Int J Environ Res Public Health , vol.4 , pp. 132-137
    • Yedjou, C.G.1    Tchounwou, P.B.2
  • 19
    • 79957894498 scopus 로고    scopus 로고
    • Hydrogen-rich medium protects human skin fibroblasts from high glucose or mannitol induced oxidative damage
    • Yu P, Wang Z, Sun X, Chen X, Zeng S, Chen L, et al. Hydrogen-rich medium protects human skin fibroblasts from high glucose or mannitol induced oxidative damage. Biochem Biophys Res Commun 2011; 409:350-355.
    • (2011) Biochem Biophys Res Commun , vol.409 , pp. 350-355
    • Yu, P.1    Wang, Z.2    Sun, X.3    Chen, X.4    Zeng, S.5    Chen, L.6
  • 20
    • 41549115946 scopus 로고    scopus 로고
    • Reactive oxygen speciesmediated pancreatic beta-cell death is regulated by interactions between stress-Activated protein kinases, p38 and c-jun n-terminal kinase, and mitogenactivated protein kinase phosphatases
    • Hou N, Torii S, Saito N, Hosaka M, Takeuchi T. Reactive oxygen speciesmediated pancreatic beta-cell death is regulated by interactions between stress-Activated protein kinases, p38 and c-Jun N-terminal kinase, and mitogenactivated protein kinase phosphatases. Endocrinology 2008; 149:1654-1665.
    • (2008) Endocrinology , vol.149 , pp. 1654-1665
    • Hou, N.1    Torii, S.2    Saito, N.3    Hosaka, M.4    Takeuchi, T.5
  • 21
    • 60749106661 scopus 로고    scopus 로고
    • Pseudolaric acid b-induced apoptosis through p53-dependent pathway in human gastric carcinoma cells
    • Meng AG, Jiang LL. Pseudolaric acid B-induced apoptosis through p53-dependent pathway in human gastric carcinoma cells. J Asian Nat Prod Res 2009; 11:142-152.
    • (2009) J Asian Nat Prod Res , vol.11 , pp. 142-152
    • Meng, A.G.1    Jiang, L.L.2
  • 22
    • 75049084688 scopus 로고    scopus 로고
    • Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, dna damage and early hepatocarcinogenesis in rat: Role of nrf2, p53, p38 and phase-ii enzymes
    • Tripathi DN, Jena GB. Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, DNA damage and early hepatocarcinogenesis in rat: role of Nrf2, p53, p38 and phase-II enzymes. Mutat Res 2010; 696:69-80.
    • (2010) Mutat Res , vol.696 , pp. 69-80
    • Tripathi, D.N.1    Jena, G.B.2
  • 23
    • 84857116578 scopus 로고    scopus 로고
    • Reactive oxygen species (ros) homeostasis and redox regulation in cellular signaling
    • Ray PD, Huang BW, Tsuji Y. Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling. Cell Signal 2012; 24:981-990.
    • (2012) Cell Signal , vol.24 , pp. 981-990
    • Ray, P.D.1    Huang, B.W.2    Tsuji, Y.3
  • 24
    • 84901236437 scopus 로고    scopus 로고
    • Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ros-mediated signaling
    • Fan C, Zheng W, Fu X, Li X, Wong YS, Chen T. Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling. Oncotarget 2014; 5:2853-2863.
    • (2014) Oncotarget , vol.5 , pp. 2853-2863
    • Fan, C.1    Zheng, W.2    Fu, X.3    Li, X.4    Wong, Y.S.5    Chen, T.6
  • 25
    • 84895926310 scopus 로고    scopus 로고
    • 9-Hydroxypheophorbide alpha-mediated photodynamic therapy induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in Hep-2 cells via ROS-mediated suppression of the ERK pathway
    • Zhang H, Shen B, Swinarska JT, Li W, Xiao K, He P. 9-Hydroxypheophorbide alpha-mediated photodynamic therapy induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in Hep-2 cells via ROS-mediated suppression of the ERK pathway. Photodiagnosis Photodyn Ther 2014; 11:55-62.
    • (2014) Photodiagnosis Photodyn Ther , vol.11 , pp. 55-62
    • Zhang, H.1    Shen, B.2    Swinarska, J.T.3    Li, W.4    Xiao, K.5    He, P.6
  • 27
    • 84901745831 scopus 로고    scopus 로고
    • Mgr1-Ag/37lrp induces cell adhesion-mediated drug resistance through fak/pi3k and mapk pathway in gastric cancer
    • Sun L, Liu L, Liu X, Wang Y, Li M, Yao L, et al. MGr1-Ag/37LRP induces cell adhesion-mediated drug resistance through FAK/PI3K and MAPK pathway in gastric cancer. Cancer Sci 2014; 105:651-659.
    • (2014) Cancer Sci , vol.105 , pp. 651-659
    • Sun, L.1    Liu, L.2    Liu, X.3    Wang, Y.4    Li, M.5    Yao, L.6
  • 28
    • 70349732865 scopus 로고    scopus 로고
    • Adhesion-mediated apoptosis resistance in cancer
    • Westhoff MA, Fulda S. Adhesion-mediated apoptosis resistance in cancer. Drug Resist Updat 2009; 12:127-136.
    • (2009) Drug Resist Updat , vol.12 , pp. 127-136
    • Westhoff, M.A.1    Fulda, S.2
  • 29
    • 84899819459 scopus 로고    scopus 로고
    • Tetrachlorobenzoquinone induces acute liver injury, up-regulates ho-1 and nqo1 expression in mice model: The protective role of chlorogenic acid
    • Xu D, Hu L, Xia X, Song J, Li L, Song E, et al. Tetrachlorobenzoquinone induces acute liver injury, up-regulates HO-1 and NQO1 expression in mice model: the protective role of chlorogenic acid. Environ Toxicol Pharmacol 2014; 37:1212-1220.
    • (2014) Environ Toxicol Pharmacol , vol.37 , pp. 1212-1220
    • Xu, D.1    Hu, L.2    Xia, X.3    Song, J.4    Li, L.5    Song, E.6
  • 30
    • 23044442718 scopus 로고    scopus 로고
    • Inhibition of activator protein-1, nf-kappab, and mapks and induction of phase 2 detoxifying enzyme activity by chlorogenic acid
    • Feng R, Lu Y, Bowman LL, Qian Y, Castranova V, Ding M. Inhibition of activator protein-1, NF-kappaB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid. J Biol Chem 2005; 280:27888-27895.
    • (2005) J Biol Chem , vol.280 , pp. 27888-27895
    • Feng, R.1    Lu, Y.2    Bowman, L.L.3    Qian, Y.4    Castranova, V.5    Ding, M.6
  • 31
    • 33645872700 scopus 로고    scopus 로고
    • The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression
    • Belkaid A, Currie JC, Desgagnes J, Annabi B. The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression. Cancer Cell Int 2006; 6:7.
    • (2006) Cancer Cell Int , vol.6 , pp. 7
    • Belkaid, A.1    Currie, J.C.2    Desgagnes, J.3    Annabi, B.4
  • 32
    • 80053641129 scopus 로고    scopus 로고
    • Inhibitory effect of antioxidant extracts from various potatoes on the proliferation of human colon and liver cancer cells
    • Wang Q, Chen Q, He M, Mir P, Su J, Yang Q. Inhibitory effect of antioxidant extracts from various potatoes on the proliferation of human colon and liver cancer cells. Nutr Cancer 2011; 63:1044-1052.
    • (2011) Nutr Cancer , vol.63 , pp. 1044-1052
    • Wang, Q.1    Chen, Q.2    He, M.3    Mir, P.4    Su, J.5    Yang, Q.6
  • 34
    • 84871491627 scopus 로고    scopus 로고
    • Ras/raf/mek/erk and pi3k/pten/akt/mtor cascade inhibitors: How mutations can result in therapy resistance and how to overcome resistance
    • McCubrey J.A.,Steelman L.S.,Chappell W.H.,Abrams S.L.,Franklin R.A.,Montalto G.,et al. Ras/raf/mek/erk and pi3k/pten/akt/mtor cascade inhibitors: How mutations can result in therapy resistance and how to overcome resistance Oncotarget 2012 3 1068-1111
    • (2012) Oncotarget , vol.3 , pp. 1068-1111
    • McCubrey, J.A.1    Steelman, L.S.2    Chappell, W.H.3    Abrams, S.L.4    Franklin, R.A.5    Montalto, G.6


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