Pseudolaric acid B-induced apoptosis through p53-dependent pathway in human gastric carcinoma cells

Journal of Asian Natural Products Research

Volumn 11, Issue 2, 2009, Pages 142-152

  Meng, Ai Guo ^a,b   Jiang, Ling Ling ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b NORTH CHINA COAL MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; bcl 2; Caspase 3; Fas; p53; Pseudolaric acid B

Indexed keywords

CASPASE 3; CYCLIN DEPENDENT KINASE INHIBITOR 1A; FAS ANTIGEN; MESSENGER RNA; PROTEIN BCL 2; PROTEIN P53; PSEUDOLARIC ACID B;

ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN MGC803; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; HUMAN; HUMAN CELL; IC 50; MEDICINAL PLANT; PSEUDOLARIX KAEMPFERI; STAINING; STOMACH CARCINOMA; TUMOR CELL LINE; UPREGULATION;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CELL CYCLE; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; GENES, BCL-2; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PINACEAE; STOMACH NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

PSEUDOLARIX KAEMPFERI;

EID: 60749106661     PISSN: 10286020     EISSN: 14772213     Source Type: Journal    
DOI: 10.1080/10286020802573420     Document Type: Article

References (21)

1. E. Li, A. Clark, and C. Hufford, J. Nat. Prod. 58, 57 (1995).
2. S.P. Yang, L. Dong, Y. Wang, Y. Wu, and J.M. Yue, Bioorg. Med. Chem. 11, 4577 (2003).
3. W.C. Wang, Z.P. Gu, A. Koo, and W.S. Chen, Acta Pharmacol. Sin. 12, 423 (1991).
4. W.F. Tan, X.W. Zhang, M.H. Li, J.M. Yue, Y. Chen, L.P. Lin, and J. Ding, Eur. J. Pharmacol. 499, 219 (2004).
5. M.H. Li, Z.H. Miao, W.F. Tan, J.M. Yue, C. Zhang, L.P. Lin, X.W. Zhang, and J. Ding, Clin. Cancer Res. 10, 8266 (2004).
6. D.J. Pan, Z.L. Li, C.Q. Hu, K. Chen, J.J. Chang, and K.H. Lee, Planta Med. 56, 383 (1990).
7. J.K. Ko, W.C. Leunq, W.K. Ho, and P. Chiu, Eur. J. Pharmacol. 559, 1 (2007).
8. J.H. Yu, Q. Cui, Y.Y. Jiang, W. Yang, S.I. Tashiro, S. Onodera, and T. Ikejima, Acta Pharmacol. Sin. 28, 1975 (2007).
9. X.F. Gong, M.W. Wang, S.I. Tashiro, S. Onodera, and T. Ikejima, Arch. Pharm. Res. 28, 68 (2005).
10. G.I. Evan and K.H. Vousden, Nature 411, 342 (2001).
11. S. Benchimol, Cell Death Differ. 8, 1049 (2001).
12. C. Huang, W.Y. Ma, A. Goranson, and Z. Dong, Carcinogenesis 20, 237 (1999).
13. K.S. Li, X.F. Gu, P. Li, Y. Zhang, Y.S. Zhao, Z.J. Yao, N.Q. Qu, and B.Y. Wang, World J. Gastroenterol. 11, 7555 (2005).
14. A. Vidal and A. Koff, Gene 247, 1 (2000).
15. C.J. Sherr, Cell 79, 551 (1994).
16. M.L. Agarwal, A. Agarwal, W.R. Taylor, and G.R. Stark, Proc. Natl Acad. Sci. USA 92, 8493 (1995).
17. A.B. Niculescu III, X. Chen, M. Smeets, L. Hengst, C. Prives, and S.I. Reed, Mol. Cell. Biol. 18, 629 (1998).
18. F. Bunz, A. Dutriaux, C. Lengauer, T. Waldman, S. Zhou, J.P. Brown, J.M. Sedivy, K.W. Kinzler, and B. Vogelstein, Science 282, 1497 (1998).
19. I.V. Beletskaya, L.V. Nikonova, and I.P. Beletsky, FEBS Lett. 412, 91 (1997).
20. K. Kannan, N. Amariglio, G. Rechavi, J. Jakob-Hirsch, I. Kela, N. Kaminski, G. Getz, E. Domany, and D. Givol, Oncogene 20, 2225 (2001).
21. W.R. Lee, S.C. Shen, H.Y. Lin, W.C. Hou, L.L. Yang, and Y.C. Chen, Biochem. Pharmacol. 63, 225 (2002).