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Volumn 2015, Issue , 2015, Pages

Reprogramming with small molecules instead of exogenous transcription factors

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYLSEROTONIN; 4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; 6 [[2 [[4 (2,4 DICHLOROPHENYL) 5 (4 METHYL 1H IMIDAZOL 2 YL) 2 PYRIMIDINYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; ASCORBIC ACID; AZACITIDINE; BAYK 8644; BUTYRIC ACID; CALCIUM CHANNEL STIMULATING AGENT; CHEMICAL COMPOUND; FORSKOLIN; KENPAULLONE; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; N (1 BENZYL 4 PIPERIDINYL) 2 (HEXAHYDRO 4 METHYL 1H 1,4 DIAZEPIN 1 YL) 6,7 DIMETHOXY 4 QUINAZOLINAMINE; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; OCTAMER TRANSCRIPTION FACTOR 4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; SMALL MOLECULE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX2; TRANSFORMING GROWTH FACTOR BETA; TRANYLCYPROMINE; TRICHOSTATIN A; UNCLASSIFIED DRUG; UVOMORULIN; VALPROIC ACID; VORINOSTAT;

EID: 84928152056     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2015/794632     Document Type: Article
Times cited : (65)

References (81)
  • 1
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • K. Takahashi, K. Tanabe, M. Ohnuki et al., "Induction of pluripotent stem cells from adult human fibroblasts by defined factors, " Cell, vol. 131, no. 5, pp. 861-872, 2007.
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 2
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • J. Yu, M. A. Vodyanik, K. Smuga-Otto et al., "Induced pluripotent stem cell lines derived from human somatic cells, " Science, vol. 318, pp. 1917-1920, 2007.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 3
    • 67649222358 scopus 로고    scopus 로고
    • Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
    • M. H. Chin, M. J. Mason, W. Xie et al., "Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures, " Cell Stem Cell, vol. 5, no. 1, pp. 111-123, 2009.
    • (2009) Cell Stem Cell , vol.5 , Issue.1 , pp. 111-123
    • Chin, M.H.1    Mason, M.J.2    Xie, W.3
  • 4
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • K. Takahashi and S. Yamanaka, "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, " Cell, vol. 126, no. 4, pp. 663-676, 2006.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 5
    • 39149086020 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from fibroblast cultures
    • K. Takahashi, K. Okita, M. Nakagawa, and S. Yamanaka, "Induction of pluripotent stem cells from fibroblast cultures, " Nature Protocols, vol. 2, no. 12, pp. 3081-3089, 2007.
    • (2007) Nature Protocols , vol.2 , Issue.12 , pp. 3081-3089
    • Takahashi, K.1    Okita, K.2    Nakagawa, M.3    Yamanaka, S.4
  • 6
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • K. Okita, T. Ichisaka, and S. Yamanaka, "Generation of germline-competent induced pluripotent stem cells, " Nature, vol. 448, no. 7151, pp. 313-317, 2007.
    • (2007) Nature , vol.448 , Issue.7151 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 7
    • 85027958626 scopus 로고    scopus 로고
    • Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
    • Y. Ohi, H. Qin, C. Hong et al., "Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells, " Nature Cell Biology, vol. 13, no. 5, pp. 541-549, 2011.
    • (2011) Nature Cell Biology , vol.13 , Issue.5 , pp. 541-549
    • Ohi, Y.1    Qin, H.2    Hong, C.3
  • 8
    • 84855490676 scopus 로고    scopus 로고
    • Highly efficient derivation of ventricular cardiomyocytes frominduced pluripotent stem cells with a distinct epigenetic signature
    • H. Xu, B. A. Yi, H. Wu et al., "Highly efficient derivation of ventricular cardiomyocytes frominduced pluripotent stem cells with a distinct epigenetic signature, " Cell Research, vol. 22, no. 1, pp. 142-154, 2012.
    • (2012) Cell Research , vol.22 , Issue.1 , pp. 142-154
    • Xu, H.1    Yi, B.A.2    Wu, H.3
  • 9
    • 79959992876 scopus 로고    scopus 로고
    • Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells
    • O. Bar-Nur, H. A. Russ, S. Efrat, and N. Benvenisty, "Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells, " Cell Stem Cell, vol. 9, no. 1, pp. 17-23, 2011.
    • (2011) Cell Stem Cell , vol.9 , Issue.1 , pp. 17-23
    • Bar-Nur, O.1    Russ, H.A.2    Efrat, S.3    Benvenisty, N.4
  • 10
    • 84860530018 scopus 로고    scopus 로고
    • Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells
    • S. B. Lee, D. Seo, D. Choi et al., "Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells, " Stem Cells, vol. 30, no. 5, pp. 997-1007, 2012.
    • (2012) Stem Cells , vol.30 , Issue.5 , pp. 997-1007
    • Lee, S.B.1    Seo, D.2    Choi, D.3
  • 11
    • 79952264847 scopus 로고    scopus 로고
    • Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
    • R. Lister, M. Pelizzola, Y. S. Kida et al., "Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells, " Nature, vol. 471, no. 7336, pp. 68-73, 2011.
    • (2011) Nature , vol.471 , Issue.7336 , pp. 68-73
    • Lister, R.1    Pelizzola, M.2    Kida, Y.S.3
  • 12
    • 79957807595 scopus 로고    scopus 로고
    • Immunogenicity of induced pluripotent stem cells
    • T. Zhao, Z.-N. Zhang, Z. Rong, and Y. Xu, "Immunogenicity of induced pluripotent stem cells, " Nature, vol. 474, no. 7350, pp. 212-215, 2011.
    • (2011) Nature , vol.474 , Issue.7350 , pp. 212-215
    • Zhao, T.1    Zhang, Z.-N.2    Rong, Z.3    Xu, Y.4
  • 13
    • 84866772874 scopus 로고    scopus 로고
    • Excision of a viral reprogramming cassette by delivery of synthetic CremRNA
    • chapter 4, unit 4A. John Wiley and Sons, Hoboken, NJ, USA
    • Y. H. Loh, J. C. Yang, A. de losAngeles et al., "Excision of a viral reprogramming cassette by delivery of synthetic CremRNA, " in Current Protocols in Stem Cell Biology, chapter 4, unit 4A. 5, John Wiley and Sons, Hoboken, NJ, USA, 2012.
    • (2012) Current Protocols in Stem Cell Biology , vol.5
    • Loh, Y.H.1    De, L.A.2    Yang, J.C.3
  • 14
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    • K. Kaji, K. Norrby, A. Paca, M. Mileikovsky, P. Mohseni, and K. Woltjen, "Virus-free induction of pluripotency and subsequent excision of reprogramming factors, " Nature, vol. 458, no. 7239, pp. 771-775, 2009.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3    Mileikovsky, M.4    Mohseni, P.5    Woltjen, K.6
  • 15
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stemcells
    • K. Woltjen, I. P. Michael, P. Mohseni et al., "PiggyBac transposition reprograms fibroblasts to induced pluripotent stemcells, " Nature, vol. 458, no. 7239, pp. 766-770, 2009.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3
  • 16
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • M. Stadtfeld, M. Nagaya, J. Utikal, G. Weir, and K. Hochedlinger, "Induced pluripotent stem cells generated without viral integration, " Science, vol. 322, no. 5903, pp. 945-949, 2008.
    • (2008) Science , vol.322 , Issue.5903 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3    Weir, G.4    Hochedlinger, K.5
  • 17
    • 72849137462 scopus 로고    scopus 로고
    • Adenoviral gene delivery can reprogramhuman fibroblasts to induced pluripotent stemcells
    • W. Zhou and C. R. Freed, "Adenoviral gene delivery can reprogramhuman fibroblasts to induced pluripotent stemcells, " Stem Cells, vol. 27, no. 11, pp. 2667-2674, 2009.
    • (2009) Stem Cells , vol.27 , Issue.11 , pp. 2667-2674
    • Zhou, W.1    Freed, C.R.2
  • 18
    • 70450265981 scopus 로고    scopus 로고
    • Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
    • N. Fusaki, H. Ban, A. Nishiyama, K. Saeki, and M. Hasegawa, "Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome, " Proceedings of the Japan Academy Series B: Physical and Biological Sciences, vol. 85, no. 8, pp. 348-362, 2009.
    • (2009) Proceedings of the Japan Academy Series B: Physical and Biological Sciences , vol.85 , Issue.8 , pp. 348-362
    • Fusaki, N.1    Ban, H.2    Nishiyama, A.3    Saeki, K.4    Hasegawa, M.5
  • 19
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • K. Okita, M. Nakagawa, H. Hyenjong, T. Ichisaka, and S. Yamanaka, "Generation of mouse induced pluripotent stem cells without viral vectors, " Science, vol. 322, no. 5903, pp. 949-953, 2008.
    • (2008) Science , vol.322 , Issue.5903 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3    Ichisaka, T.4    Yamanaka, S.5
  • 20
    • 65649116572 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells free of vector and transgene sequences
    • J. Yu, K. Hu, K. Smuga-Otto et al., "Human induced pluripotent stem cells free of vector and transgene sequences, " Science, vol. 324, no. 5928, pp. 797-801, 2009.
    • (2009) Science , vol.324 , Issue.5928 , pp. 797-801
    • Yu, J.1    Hu, K.2    Smuga-Otto, K.3
  • 21
    • 79955634826 scopus 로고    scopus 로고
    • A more efficient method to generate integration-free human iPS cells
    • K. Okita, Y. Matsumura, Y. Sato et al., "A more efficient method to generate integration-free human iPS cells, " Nature Methods, vol. 8, pp. 409-412, 2011.
    • (2011) Nature Methods , vol.8 , pp. 409-412
    • Okita, K.1    Matsumura, Y.2    Sato, Y.3
  • 22
    • 77649275936 scopus 로고    scopus 로고
    • A nonviral minicircle vector for deriving human iPS cells
    • F. Jia, K. D. Wilson, N. Sun et al., "A nonviral minicircle vector for deriving human iPS cells, " Nature Methods, vol. 7, pp. 197-199, 2010.
    • (2010) Nature Methods , vol.7 , pp. 197-199
    • Jia, F.1    Wilson, K.D.2    Sun, N.3
  • 23
    • 84866666977 scopus 로고    scopus 로고
    • Efficient generation of virus-free iPS cells using liposomal magnetofection
    • Article ID e45812
    • H. Y. Park, E. H. Noh, H.-M. Chung, M.-J. Kang, E. Y. Kim, and S. P. Park, "Efficient generation of virus-free iPS cells using liposomal magnetofection, " PLoS ONE, vol. 7, no. 9, Article ID e45812, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.9
    • Park, H.Y.1    Noh, E.H.2    Chung, H.-M.3    Kang, M.-J.4    Kim, E.Y.5    Park, S.P.6
  • 24
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • H. Zhou, S. Wu, J. Y. Joo et al., "Generation of induced pluripotent stem cells using recombinant proteins, " Cell Stem Cell, vol. 4, no. 5, pp. 381-384, 2009.
    • (2009) Cell Stem Cell , vol.4 , Issue.5 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3
  • 25
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • D. Kim, C.-H. Kim, J.-I. Moon et al., "Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins, " Cell Stem Cell, vol. 4, no. 6, pp. 472-476, 2009.
    • (2009) Cell Stem Cell , vol.4 , Issue.6 , pp. 472-476
    • Kim, D.1    Kim, C.-H.2    Moon, J.-I.3
  • 26
    • 77958536106 scopus 로고    scopus 로고
    • Highly efficient reprogramming to pluripotency and directed differentiation of human cells with syntheticmodifiedmRNA
    • L. Warren, P. D. Manos, T. Ahfeldt et al., "Highly efficient reprogramming to pluripotency and directed differentiation of human cells with syntheticmodifiedmRNA, " Cell Stem Cell, vol. 7, no. 5, pp. 618-630, 2010.
    • (2010) Cell Stem Cell , vol.7 , Issue.5 , pp. 618-630
    • Warren, L.1    Manos, P.D.2    Ahfeldt, T.3
  • 27
    • 84881256653 scopus 로고    scopus 로고
    • Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds
    • P. Hou, Y. Li, X. Zhang et al., "Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds, " Science, vol. 341, no. 6146, pp. 651-654, 2013.
    • (2013) Science , vol.341 , Issue.6146 , pp. 651-654
    • Hou, P.1    Li, Y.2    Zhang, X.3
  • 28
    • 34249909232 scopus 로고    scopus 로고
    • Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
    • N. Maherali, R. Sridharan, W. Xie et al., "Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution, " Cell Stem Cell, vol. 1, no. 1, pp. 55-70, 2007.
    • (2007) Cell Stem Cell , vol.1 , Issue.1 , pp. 55-70
    • Maherali, N.1    Sridharan, R.2    Xie, W.3
  • 29
    • 46449094276 scopus 로고    scopus 로고
    • Dissecting direct reprogramming through integrative genomic analysis
    • T. S. Mikkelsen, J. Hanna, X. Zhang et al., "Dissecting direct reprogramming through integrative genomic analysis, " Nature, vol. 454, no. 7200, pp. 49-55, 2008.
    • (2008) Nature , vol.454 , Issue.7200 , pp. 49-55
    • Mikkelsen, T.S.1    Hanna, J.2    Zhang, X.3
  • 30
    • 58249085824 scopus 로고    scopus 로고
    • Role of the murine reprogramming factors in the induction of pluripotency
    • R. Sridharan, J. Tchieu, M. J. Mason et al., "Role of the murine reprogramming factors in the induction of pluripotency, " Cell, vol. 136, no. 2, pp. 364-377, 2009.
    • (2009) Cell , vol.136 , Issue.2 , pp. 364-377
    • Sridharan, R.1    Tchieu, J.2    Mason, M.J.3
  • 31
    • 46949085597 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells by defined factors is greatly improved by smallmolecule compounds
    • D. Huangfu, R. Maehr, W. Guo et al., "Induction of pluripotent stem cells by defined factors is greatly improved by smallmolecule compounds, " Nature Biotechnology, vol. 26, no. 7, pp. 795-797, 2008.
    • (2008) Nature Biotechnology , vol.26 , Issue.7 , pp. 795-797
    • Huangfu, D.1    Maehr, R.2    Guo, W.3
  • 32
    • 54949115497 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
    • Y. Shi, C. Desponts, J. T. Do, H. S. Hahm, H. R. Schöler, and S. Ding, "Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds, " Cell Stem Cell, vol. 3, no. 5, pp. 568-574, 2008.
    • (2008) Cell Stem Cell , vol.3 , Issue.5 , pp. 568-574
    • Shi, Y.1    Desponts, C.2    Do, J.T.3    Hahm, H.S.4    Schöler, H.R.5    Ding, S.6
  • 33
    • 44349103591 scopus 로고    scopus 로고
    • A combined chemical and genetic approach for the generation of induced pluripotent stemcells
    • Y. Shi, J. T. Do, C. Desponts, H. S. Hahm, H. R. Schöler, and S. Ding, "A combined chemical and genetic approach for the generation of induced pluripotent stemcells, " Cell Stem Cell, vol. 2, pp. 525-528, 2008.
    • (2008) Cell Stem Cell , vol.2 , pp. 525-528
    • Shi, Y.1    Do, J.T.2    Desponts, C.3    Hahm, H.S.4    Schöler, H.R.5    Ding, S.6
  • 34
    • 84871935467 scopus 로고    scopus 로고
    • Cellular reprogramming: A small molecule perspective
    • B. Nie, H. Wang, T. Laurent, and S. Ding, "Cellular reprogramming: a small molecule perspective, " Current Opinion in Cell Biology, vol. 24, no. 6, pp. 784-792, 2012.
    • (2012) Current Opinion in Cell Biology , vol.24 , Issue.6 , pp. 784-792
    • Nie, B.1    Wang, H.2    Laurent, T.3    Ding, S.4
  • 35
    • 73049086022 scopus 로고    scopus 로고
    • Generation of humaninduced pluripotent stem cells in the absence of exogenous Sox2
    • W. Li, H. Zhou, R. Abujarour et al., "Generation of humaninduced pluripotent stem cells in the absence of exogenous Sox2, " Stem Cells, vol. 27, no. 12, pp. 2992-3000, 2009.
    • (2009) Stem Cells , vol.27 , Issue.12 , pp. 2992-3000
    • Li, W.1    Zhou, H.2    Abujarour, R.3
  • 36
    • 77953809032 scopus 로고    scopus 로고
    • Distinct epigenomic landscapes of pluripotent and lineage-committed human cells
    • R. D. Hawkins, G. C. Hon, L. K. Lee et al., "Distinct epigenomic landscapes of pluripotent and lineage-committed human cells, " Cell Stem Cell, vol. 6, no. 5, pp. 479-491, 2010.
    • (2010) Cell Stem Cell , vol.6 , Issue.5 , pp. 479-491
    • Hawkins, R.D.1    Hon, G.C.2    Lee, L.K.3
  • 37
    • 84878273239 scopus 로고    scopus 로고
    • Induction of pluripotency inmouse somatic cells with lineage specifiers
    • J. Shu, C. Wu, Y. Wu et al., "Induction of pluripotency inmouse somatic cells with lineage specifiers, " Cell, vol. 153, no. 5, pp. 963-975, 2013.
    • (2013) Cell , vol.153 , Issue.5 , pp. 963-975
    • Shu, J.1    Wu, C.2    Wu, Y.3
  • 39
    • 54949092372 scopus 로고    scopus 로고
    • From fibroblasts to iPS cells: Induced pluripotency by defined factors
    • R. Zhao and G. Q. Daley, "From fibroblasts to iPS cells: induced pluripotency by defined factors, " Journal of Cellular Biochemistry, vol. 105, no. 4, pp. 949-955, 2008.
    • (2008) Journal of Cellular Biochemistry , vol.105 , Issue.4 , pp. 949-955
    • Zhao, R.1    Daley, G.Q.2
  • 40
    • 80052451791 scopus 로고    scopus 로고
    • Wnt: What's Needed to maintain pluripotency?
    • H. Niwa, "Wnt: what's Needed to maintain pluripotency?" Nature Cell Biology, vol. 13, no. 9, pp. 1024-1026, 2011.
    • (2011) Nature Cell Biology , vol.13 , Issue.9 , pp. 1024-1026
    • Niwa, H.1
  • 41
    • 48149107133 scopus 로고    scopus 로고
    • Wnt signaling promotes reprogramming of somatic cells to pluripotency
    • A. Marson, R. Foreman, B. Chevalier et al., "Wnt signaling promotes reprogramming of somatic cells to pluripotency, " Cell Stem Cell, vol. 3, no. 2, pp. 132-135, 2008.
    • (2008) Cell Stem Cell , vol.3 , Issue.2 , pp. 132-135
    • Marson, A.1    Foreman, R.2    Chevalier, B.3
  • 44
    • 54949136146 scopus 로고    scopus 로고
    • Two supporting factors greatly improve the efficiency of human iPSC generation
    • Y. Zhao, X. Yin, H. Qin et al., "Two supporting factors greatly improve the efficiency of human iPSC generation, " Cell Stem Cell, vol. 3, no. 5, pp. 475-479, 2008.
    • (2008) Cell Stem Cell , vol.3 , Issue.5 , pp. 475-479
    • Zhao, Y.1    Yin, X.2    Qin, H.3
  • 45
    • 69349100179 scopus 로고    scopus 로고
    • Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
    • H. Hong, K. Takahashi, T. Ichisaka et al., "Suppression of induced pluripotent stem cell generation by the p53-p21 pathway, " Nature, vol. 460, no. 7259, pp. 1132-1135, 2009.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1132-1135
    • Hong, H.1    Takahashi, K.2    Ichisaka, T.3
  • 46
    • 69349100455 scopus 로고    scopus 로고
    • Linking the p53 tumour suppressor pathway to somatic cell reprogramming
    • T. Kawamura, J. Suzuki, Y. V. Wang et al., "Linking the p53 tumour suppressor pathway to somatic cell reprogramming, " Nature, vol. 460, no. 7259, pp. 1140-1144, 2009.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1140-1144
    • Kawamura, T.1    Suzuki, J.2    Wang, Y.V.3
  • 47
    • 69349103956 scopus 로고    scopus 로고
    • The Ink4/Arf locus is a barrier for iPS cell reprogramming
    • H. Li, M. Collado, A. Villasante et al., "The Ink4/Arf locus is a barrier for iPS cell reprogramming, " Nature, vol. 460, no. 7259, pp. 1136-1139, 2009.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1136-1139
    • Li, H.1    Collado, M.2    Villasante, A.3
  • 48
    • 69349098273 scopus 로고    scopus 로고
    • Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
    • J. Utikal, J. M. Polo, M. Stadtfeld et al., "Immortalization eliminates a roadblock during cellular reprogramming into iPS cells, " Nature, vol. 460, no. 7259, pp. 1145-1148, 2009.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1145-1148
    • Utikal, J.1    Polo, J.M.2    Stadtfeld, M.3
  • 49
    • 69349094006 scopus 로고    scopus 로고
    • A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
    • R. M. Marión, K. Strati, H. Li et al., "A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity, " Nature, vol. 460, no. 7259, pp. 1149-1153, 2009.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1149-1153
    • Marión, R.M.1    Strati, K.2    Li, H.3
  • 50
    • 69349098834 scopus 로고    scopus 로고
    • Stem cells: The promises and perils of p53
    • V. Krizhanovsky and S. W. Lowe, "Stem cells: the promises and perils of p53, " Nature, vol. 460, no. 7259, pp. 1085-1086, 2009.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1085-1086
    • Krizhanovsky, V.1    Lowe, S.W.2
  • 51
    • 13944273471 scopus 로고    scopus 로고
    • P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
    • T. Lin, C. Chao, S. Saito et al., "p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression, " Nature Cell Biology, vol. 7, no. 2, pp. 165-171, 2005.
    • (2005) Nature Cell Biology , vol.7 , Issue.2 , pp. 165-171
    • Lin, T.1    Chao, C.2    Saito, S.3
  • 52
    • 84857710723 scopus 로고    scopus 로고
    • Stem cells: Flexible friends
    • N. Shevde, "Stem cells: flexible friends, " Nature, vol. 483, no. 7387, pp. S22-S26, 2012.
    • (2012) Nature , vol.483 , Issue.7387 , pp. S22-S26
    • Shevde, N.1
  • 53
    • 73049112178 scopus 로고    scopus 로고
    • Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
    • M. A. Esteban, T. Wang, B. Qin et al., "Vitamin C enhances the generation of mouse and human induced pluripotent stem cells, " Cell Stem Cell, vol. 6, no. 1, pp. 71-79, 2010.
    • (2010) Cell Stem Cell , vol.6 , Issue.1 , pp. 71-79
    • Esteban, M.A.1    Wang, T.2    Qin, B.3
  • 54
    • 84856007232 scopus 로고    scopus 로고
    • The promise of induced pluripotent stem cells in research and therapy
    • D. A. Robinton and G. Q. Daley, "The promise of induced pluripotent stem cells in research and therapy, " Nature, vol. 481, no. 7381, pp. 295-305, 2012.
    • (2012) Nature , vol.481 , Issue.7381 , pp. 295-305
    • Robinton, D.A.1    Daley, G.Q.2
  • 55
    • 70349093119 scopus 로고    scopus 로고
    • Senescence impairs successful reprogramming to pluripotent stem cells
    • A. Banito, S. T. Rashid, J. C. Acosta et al., "Senescence impairs successful reprogramming to pluripotent stem cells, " Genes and Development, vol. 23, no. 18, pp. 2134-2139, 2009.
    • (2009) Genes and Development , vol.23 , Issue.18 , pp. 2134-2139
    • Banito, A.1    Rashid, S.T.2    Acosta, J.C.3
  • 56
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the warburg effect: The metabolic requirements of cell proliferation
    • M. G. V. Heiden, L. C. Cantley, and C. B. Thompson, "Understanding the warburg effect: the metabolic requirements of cell proliferation, " Science, vol. 324, no. 5930, pp. 1029-1033, 2009.
    • (2009) Science , vol.324 , Issue.5930 , pp. 1029-1033
    • Heiden, M.G.V.1    Cantley, L.C.2    Thompson, C.B.3
  • 57
    • 69249210977 scopus 로고    scopus 로고
    • Hypoxia enhances the generation of induced pluripotent stem cells
    • Y. Yoshida, K. Takahashi, K. Okita, T. Ichisaka, and S. Yamanaka, "Hypoxia enhances the generation of induced pluripotent stem cells, " Cell Stem Cell, vol. 5, no. 3, pp. 237-241, 2009.
    • (2009) Cell Stem Cell , vol.5 , Issue.3 , pp. 237-241
    • Yoshida, Y.1    Takahashi, K.2    Okita, K.3    Ichisaka, T.4    Yamanaka, S.5
  • 58
    • 77951002352 scopus 로고    scopus 로고
    • The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells
    • A. Prigione, B. Fauler, R. Lurz, H. Lehrach, and J. Adjaye, "The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells, " Stem Cells, vol. 28, no. 4, pp. 721-733, 2010.
    • (2010) Stem Cells , vol.28 , Issue.4 , pp. 721-733
    • Prigione, A.1    Fauler, B.2    Lurz, R.3    Lehrach, H.4    Adjaye, J.5
  • 59
    • 78649647814 scopus 로고    scopus 로고
    • Reprogramming of human primary somatic cells by OCT4 and chemical compounds
    • S. Zhu, W. Li, H. Zhou et al., "Reprogramming of human primary somatic cells by OCT4 and chemical compounds, " Cell Stem Cell, vol. 7, no. 6, pp. 651-655, 2010.
    • (2010) Cell Stem Cell , vol.7 , Issue.6 , pp. 651-655
    • Zhu, S.1    Li, W.2    Zhou, H.3
  • 60
    • 77957551870 scopus 로고    scopus 로고
    • Amesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
    • R. Li, J. Liang, S. Ni et al., "Amesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts, " Cell Stem Cell, vol. 7, no. 1, pp. 51-63, 2010.
    • (2010) Cell Stem Cell , vol.7 , Issue.1 , pp. 51-63
    • Li, R.1    Liang, J.2    Ni, S.3
  • 61
    • 77956320116 scopus 로고    scopus 로고
    • Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
    • P. Samavarchi-Tehrani, A. Golipour, L. David et al., "Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming, " Cell Stem Cell, vol. 7, no. 1, pp. 64-77, 2010.
    • (2010) Cell Stem Cell , vol.7 , Issue.1 , pp. 64-77
    • Samavarchi-Tehrani, P.1    Golipour, A.2    David, L.3
  • 62
    • 70350732790 scopus 로고    scopus 로고
    • A chemical platformfor improved induction of human iPSCs
    • T. Lin, R. Ambasudhan, X. Yuan et al., "A chemical platformfor improved induction of human iPSCs, " Nature Methods, vol. 6, no. 11, pp. 805-808, 2009.
    • (2009) Nature Methods , vol.6 , Issue.11 , pp. 805-808
    • Lin, T.1    Ambasudhan, R.2    Yuan, X.3
  • 63
    • 70350536767 scopus 로고    scopus 로고
    • A small-molecule inhibitor of tgf-β signaling replaces sox2 in reprogramming by inducing Nanog
    • J. K. Ichida, J. Blanchard, K. Lam et al., "A small-molecule inhibitor of tgf-β signaling replaces sox2 in reprogramming by inducing Nanog, " Cell Stem Cell, vol. 5, no. 5, pp. 491-503, 2009.
    • (2009) Cell Stem Cell , vol.5 , Issue.5 , pp. 491-503
    • Ichida, J.K.1    Blanchard, J.2    Lam, K.3
  • 64
    • 79953001876 scopus 로고    scopus 로고
    • Brief report: Combined chemical treatment enables Oct4-induced reprogramming frommouse embryonic fibroblasts
    • X. Yuan, H. Wan, X. Zhao, S. Zhu, Q. Zhou, and S. Ding, "Brief report: combined chemical treatment enables Oct4-induced reprogramming frommouse embryonic fibroblasts, " StemCells, vol. 29, no. 3, pp. 549-553, 2011.
    • (2011) StemCells , vol.29 , Issue.3 , pp. 549-553
    • Yuan, X.1    Wan, H.2    Zhao, X.3    Zhu, S.4    Zhou, Q.5    Ding, S.6
  • 65
    • 84919666195 scopus 로고    scopus 로고
    • Identification of a small molecule that turns on the pluripotency gene circuitry in human fibroblasts
    • G. N. Pandian, S. Sato, C. Anandhakumar et al., "Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts, " ACS Chemical Biology, vol. 9, no. 12, pp. 2729-2736, 2014.
    • (2014) ACS Chemical Biology , vol.9 , Issue.12 , pp. 2729-2736
    • Pandian, G.N.1    Sato, S.2    Anandhakumar, C.3
  • 66
    • 77950965653 scopus 로고    scopus 로고
    • Butyrate greatly enhances derivation of human induced pluripotent stemcells by promoting epigenetic remodeling and the expression of pluripotencyassociated genes
    • P. Mali, B.-K. Chou, J. Yen et al., "Butyrate greatly enhances derivation of human induced pluripotent stemcells by promoting epigenetic remodeling and the expression of pluripotencyassociated genes, " Stem Cells, vol. 28, no. 4, pp. 713-720, 2010.
    • (2010) Stem Cells , vol.28 , Issue.4 , pp. 713-720
    • Mali, P.1    Chou, B.-K.2    Yen, J.3
  • 67
    • 84870586551 scopus 로고    scopus 로고
    • A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells
    • J. Lee, Y. Xia, M.-Y. Son et al., "A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells, " Angewandte Chemie International Edition, vol. 51, no. 50, pp. 12509-12513, 2012.
    • (2012) Angewandte Chemie International Edition , vol.51 , Issue.50 , pp. 12509-12513
    • Lee, J.1    Xia, Y.2    Son, M.-Y.3
  • 68
    • 80053633785 scopus 로고    scopus 로고
    • Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells
    • Q. Wang, X. Xu, J. Li et al., "Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells, " Cell Research, vol. 21, no. 10, pp. 1424-1435, 2011.
    • (2011) Cell Research , vol.21 , Issue.10 , pp. 1424-1435
    • Wang, Q.1    Xu, X.2    Li, J.3
  • 69
    • 67650451121 scopus 로고    scopus 로고
    • ROCKinhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells
    • D. A. Claassen, M. M. Desler, and A. Rizzino, "ROCKinhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells, " Molecular Reproduction and Development, vol. 76, no. 8, pp. 722-732, 2009.
    • (2009) Molecular Reproduction and Development , vol.76 , Issue.8 , pp. 722-732
    • Claassen, D.A.1    Desler, M.M.2    Rizzino, A.3
  • 70
    • 84866992567 scopus 로고    scopus 로고
    • A kinase inhibitor screen identifies smallmolecule enhancers of reprogramming and iPS cell generation
    • article 1085
    • Z. Li and T. M. Rana, "A kinase inhibitor screen identifies smallmolecule enhancers of reprogramming and iPS cell generation, " Nature Communications, vol. 3, article 1085, 2012.
    • (2012) Nature Communications , vol.3
    • Li, Z.1    Rana, T.M.2
  • 71
    • 80052819789 scopus 로고    scopus 로고
    • Rapamycin and other longevitypromoting compounds enhance the generation of mouse induced pluripotent stem cells
    • T. Chen, L. Shen, J. Yu et al., "Rapamycin and other longevitypromoting compounds enhance the generation of mouse induced pluripotent stem cells, " Aging Cell, vol. 10, no. 5, pp. 908-911, 2011.
    • (2011) Aging Cell , vol.10 , Issue.5 , pp. 908-911
    • Chen, T.1    Shen, L.2    Yu, J.3
  • 72
    • 38349022657 scopus 로고    scopus 로고
    • Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma
    • Y. Shi, M. Zou, E. Y. Baitei et al., "Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma, " Cancer Gene Therapy, vol. 15, no. 2, pp. 101-107, 2008.
    • (2008) Cancer Gene Therapy , vol.15 , Issue.2 , pp. 101-107
    • Shi, Y.1    Zou, M.2    Baitei, E.Y.3
  • 73
    • 78650915547 scopus 로고    scopus 로고
    • Generation of iPSCs frommouse fibroblasts with a single gene, Oct4, and small molecules
    • Y. Li, Q. Zhang, X. Yin et al., "Generation of iPSCs frommouse fibroblasts with a single gene, Oct4, and small molecules, " Cell Research, vol. 21, no. 1, pp. 196-204, 2011.
    • (2011) Cell Research , vol.21 , Issue.1 , pp. 196-204
    • Li, Y.1    Zhang, Q.2    Yin, X.3
  • 74
    • 79958293319 scopus 로고    scopus 로고
    • Pan-src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells
    • J. Staerk, C. A. Lyssiotis, L. A. Medeiro et al., "Pan-src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells, " Angewandte Chemie-International Edition, vol. 50, no. 25, pp. 5734-5736, 2011.
    • (2011) Angewandte Chemie-International Edition , vol.50 , Issue.25 , pp. 5734-5736
    • Staerk, J.1    Lyssiotis, C.A.2    Medeiro, L.A.3
  • 75
    • 80052437236 scopus 로고    scopus 로고
    • Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1
    • J.-H. Moon, J. S. Heo, J. S. Kim et al., "Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1, " Cell Research, vol. 21, no. 9, pp. 1305-1315, 2011.
    • (2011) Cell Research , vol.21 , Issue.9 , pp. 1305-1315
    • Moon, J.-H.1    Heo, J.S.2    Kim, J.S.3
  • 76
    • 84900397721 scopus 로고    scopus 로고
    • Reprogram or reboot: Small molecule approaches for the production of induced pluripotent stem cells and direct cell reprogramming
    • D.-W. Jung, W.-H. Kim, and D. R. Williams, "Reprogram or reboot: small molecule approaches for the production of induced pluripotent stem cells and direct cell reprogramming, " ACS Chemical Biology, vol. 9, no. 1, pp. 80-95, 2014.
    • (2014) ACS Chemical Biology , vol.9 , Issue.1 , pp. 80-95
    • Jung, D.-W.1    Kim, W.-H.2    Williams, D.R.3
  • 77
    • 80051728762 scopus 로고    scopus 로고
    • Efficient non-viral reprogramming of myoblasts to stemness with a single small molecule to generate cardiac progenitor cells
    • Article ID e23667
    • Z. Pasha, H. K. Haider, and M. Ashraf, "Efficient non-viral reprogramming of myoblasts to stemness with a single small molecule to generate cardiac progenitor cells, " PLoS ONE, vol. 6, no. 8, Article ID e23667, 2011.
    • (2011) PLoS ONE , vol.6 , Issue.8
    • Pasha, Z.1    Haider, H.K.2    Ashraf, M.3
  • 78
    • 80052743286 scopus 로고    scopus 로고
    • Patient-specific pluripotent stem cells in neurological diseases
    • Article ID 212487, 17 pages
    • S. Durnaoglu, S. Genc, and K. Genc, "Patient-specific pluripotent stem cells in neurological diseases, " Stem Cells International, vol. 2011, Article ID 212487, 17 pages, 2011.
    • (2011) Stem Cells International , vol.2011
    • Durnaoglu, S.1    Genc, S.2    Genc, K.3
  • 79
    • 84859514692 scopus 로고    scopus 로고
    • Asmall molecule mimicking a phosphatidylinositol (4, 5)-bisphosphate binding pleckstrin homology domain
    • L. H. Mak, S. N. Georgiades, E. Rosivatz et al., "Asmall molecule mimicking a phosphatidylinositol (4, 5)-bisphosphate binding pleckstrin homology domain, " ACS Chemical Biology, vol. 6, no. 12, pp. 1382-1390, 2011.
    • (2011) ACS Chemical Biology , vol.6 , Issue.12 , pp. 1382-1390
    • Mak, L.H.1    Georgiades, S.N.2    Rosivatz, E.3
  • 80
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • Q.-L. Ying, J. Wray, J. Nichols et al., "The ground state of embryonic stem cell self-renewal, " Nature, vol. 453, no. 7194, pp. 519-523, 2008.
    • (2008) Nature , vol.453 , Issue.7194 , pp. 519-523
    • Ying, Q.-L.1    Wray, J.2    Nichols, J.3
  • 81
    • 84896093612 scopus 로고    scopus 로고
    • Platform for induction and maintenance of transgene-free hiPSCs resembling ground state pluripotent stemcells
    • B. Valamehr, M. Robinson, R. Abujarour et al., "Platform for induction and maintenance of transgene-free hiPSCs resembling ground state pluripotent stemcells, " StemCell Reports, vol. 2, no. 3, pp. 366-381, 2014.
    • (2014) StemCell Reports , vol.2 , Issue.3 , pp. 366-381
    • Valamehr, B.1    Robinson, M.2    Abujarour, R.3


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