-
1
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
K. Takahashi, K. Tanabe, M. Ohnuki et al., "Induction of pluripotent stem cells from adult human fibroblasts by defined factors, " Cell, vol. 131, no. 5, pp. 861-872, 2007.
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
2
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
J. Yu, M. A. Vodyanik, K. Smuga-Otto et al., "Induced pluripotent stem cell lines derived from human somatic cells, " Science, vol. 318, pp. 1917-1920, 2007.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
3
-
-
67649222358
-
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
-
M. H. Chin, M. J. Mason, W. Xie et al., "Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures, " Cell Stem Cell, vol. 5, no. 1, pp. 111-123, 2009.
-
(2009)
Cell Stem Cell
, vol.5
, Issue.1
, pp. 111-123
-
-
Chin, M.H.1
Mason, M.J.2
Xie, W.3
-
4
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
K. Takahashi and S. Yamanaka, "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, " Cell, vol. 126, no. 4, pp. 663-676, 2006.
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
5
-
-
39149086020
-
Induction of pluripotent stem cells from fibroblast cultures
-
K. Takahashi, K. Okita, M. Nakagawa, and S. Yamanaka, "Induction of pluripotent stem cells from fibroblast cultures, " Nature Protocols, vol. 2, no. 12, pp. 3081-3089, 2007.
-
(2007)
Nature Protocols
, vol.2
, Issue.12
, pp. 3081-3089
-
-
Takahashi, K.1
Okita, K.2
Nakagawa, M.3
Yamanaka, S.4
-
6
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
K. Okita, T. Ichisaka, and S. Yamanaka, "Generation of germline-competent induced pluripotent stem cells, " Nature, vol. 448, no. 7151, pp. 313-317, 2007.
-
(2007)
Nature
, vol.448
, Issue.7151
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
7
-
-
85027958626
-
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
-
Y. Ohi, H. Qin, C. Hong et al., "Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells, " Nature Cell Biology, vol. 13, no. 5, pp. 541-549, 2011.
-
(2011)
Nature Cell Biology
, vol.13
, Issue.5
, pp. 541-549
-
-
Ohi, Y.1
Qin, H.2
Hong, C.3
-
8
-
-
84855490676
-
Highly efficient derivation of ventricular cardiomyocytes frominduced pluripotent stem cells with a distinct epigenetic signature
-
H. Xu, B. A. Yi, H. Wu et al., "Highly efficient derivation of ventricular cardiomyocytes frominduced pluripotent stem cells with a distinct epigenetic signature, " Cell Research, vol. 22, no. 1, pp. 142-154, 2012.
-
(2012)
Cell Research
, vol.22
, Issue.1
, pp. 142-154
-
-
Xu, H.1
Yi, B.A.2
Wu, H.3
-
9
-
-
79959992876
-
Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells
-
O. Bar-Nur, H. A. Russ, S. Efrat, and N. Benvenisty, "Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells, " Cell Stem Cell, vol. 9, no. 1, pp. 17-23, 2011.
-
(2011)
Cell Stem Cell
, vol.9
, Issue.1
, pp. 17-23
-
-
Bar-Nur, O.1
Russ, H.A.2
Efrat, S.3
Benvenisty, N.4
-
10
-
-
84860530018
-
Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells
-
S. B. Lee, D. Seo, D. Choi et al., "Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells, " Stem Cells, vol. 30, no. 5, pp. 997-1007, 2012.
-
(2012)
Stem Cells
, vol.30
, Issue.5
, pp. 997-1007
-
-
Lee, S.B.1
Seo, D.2
Choi, D.3
-
11
-
-
79952264847
-
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
-
R. Lister, M. Pelizzola, Y. S. Kida et al., "Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells, " Nature, vol. 471, no. 7336, pp. 68-73, 2011.
-
(2011)
Nature
, vol.471
, Issue.7336
, pp. 68-73
-
-
Lister, R.1
Pelizzola, M.2
Kida, Y.S.3
-
12
-
-
79957807595
-
Immunogenicity of induced pluripotent stem cells
-
T. Zhao, Z.-N. Zhang, Z. Rong, and Y. Xu, "Immunogenicity of induced pluripotent stem cells, " Nature, vol. 474, no. 7350, pp. 212-215, 2011.
-
(2011)
Nature
, vol.474
, Issue.7350
, pp. 212-215
-
-
Zhao, T.1
Zhang, Z.-N.2
Rong, Z.3
Xu, Y.4
-
13
-
-
84866772874
-
Excision of a viral reprogramming cassette by delivery of synthetic CremRNA
-
chapter 4, unit 4A. John Wiley and Sons, Hoboken, NJ, USA
-
Y. H. Loh, J. C. Yang, A. de losAngeles et al., "Excision of a viral reprogramming cassette by delivery of synthetic CremRNA, " in Current Protocols in Stem Cell Biology, chapter 4, unit 4A. 5, John Wiley and Sons, Hoboken, NJ, USA, 2012.
-
(2012)
Current Protocols in Stem Cell Biology
, vol.5
-
-
Loh, Y.H.1
De, L.A.2
Yang, J.C.3
-
14
-
-
64749111225
-
Virus-free induction of pluripotency and subsequent excision of reprogramming factors
-
K. Kaji, K. Norrby, A. Paca, M. Mileikovsky, P. Mohseni, and K. Woltjen, "Virus-free induction of pluripotency and subsequent excision of reprogramming factors, " Nature, vol. 458, no. 7239, pp. 771-775, 2009.
-
(2009)
Nature
, vol.458
, Issue.7239
, pp. 771-775
-
-
Kaji, K.1
Norrby, K.2
Paca, A.3
Mileikovsky, M.4
Mohseni, P.5
Woltjen, K.6
-
15
-
-
64749083939
-
PiggyBac transposition reprograms fibroblasts to induced pluripotent stemcells
-
K. Woltjen, I. P. Michael, P. Mohseni et al., "PiggyBac transposition reprograms fibroblasts to induced pluripotent stemcells, " Nature, vol. 458, no. 7239, pp. 766-770, 2009.
-
(2009)
Nature
, vol.458
, Issue.7239
, pp. 766-770
-
-
Woltjen, K.1
Michael, I.P.2
Mohseni, P.3
-
16
-
-
55849115999
-
Induced pluripotent stem cells generated without viral integration
-
M. Stadtfeld, M. Nagaya, J. Utikal, G. Weir, and K. Hochedlinger, "Induced pluripotent stem cells generated without viral integration, " Science, vol. 322, no. 5903, pp. 945-949, 2008.
-
(2008)
Science
, vol.322
, Issue.5903
, pp. 945-949
-
-
Stadtfeld, M.1
Nagaya, M.2
Utikal, J.3
Weir, G.4
Hochedlinger, K.5
-
17
-
-
72849137462
-
Adenoviral gene delivery can reprogramhuman fibroblasts to induced pluripotent stemcells
-
W. Zhou and C. R. Freed, "Adenoviral gene delivery can reprogramhuman fibroblasts to induced pluripotent stemcells, " Stem Cells, vol. 27, no. 11, pp. 2667-2674, 2009.
-
(2009)
Stem Cells
, vol.27
, Issue.11
, pp. 2667-2674
-
-
Zhou, W.1
Freed, C.R.2
-
18
-
-
70450265981
-
Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
-
N. Fusaki, H. Ban, A. Nishiyama, K. Saeki, and M. Hasegawa, "Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome, " Proceedings of the Japan Academy Series B: Physical and Biological Sciences, vol. 85, no. 8, pp. 348-362, 2009.
-
(2009)
Proceedings of the Japan Academy Series B: Physical and Biological Sciences
, vol.85
, Issue.8
, pp. 348-362
-
-
Fusaki, N.1
Ban, H.2
Nishiyama, A.3
Saeki, K.4
Hasegawa, M.5
-
19
-
-
55849117368
-
Generation of mouse induced pluripotent stem cells without viral vectors
-
K. Okita, M. Nakagawa, H. Hyenjong, T. Ichisaka, and S. Yamanaka, "Generation of mouse induced pluripotent stem cells without viral vectors, " Science, vol. 322, no. 5903, pp. 949-953, 2008.
-
(2008)
Science
, vol.322
, Issue.5903
, pp. 949-953
-
-
Okita, K.1
Nakagawa, M.2
Hyenjong, H.3
Ichisaka, T.4
Yamanaka, S.5
-
20
-
-
65649116572
-
Human induced pluripotent stem cells free of vector and transgene sequences
-
J. Yu, K. Hu, K. Smuga-Otto et al., "Human induced pluripotent stem cells free of vector and transgene sequences, " Science, vol. 324, no. 5928, pp. 797-801, 2009.
-
(2009)
Science
, vol.324
, Issue.5928
, pp. 797-801
-
-
Yu, J.1
Hu, K.2
Smuga-Otto, K.3
-
21
-
-
79955634826
-
A more efficient method to generate integration-free human iPS cells
-
K. Okita, Y. Matsumura, Y. Sato et al., "A more efficient method to generate integration-free human iPS cells, " Nature Methods, vol. 8, pp. 409-412, 2011.
-
(2011)
Nature Methods
, vol.8
, pp. 409-412
-
-
Okita, K.1
Matsumura, Y.2
Sato, Y.3
-
22
-
-
77649275936
-
A nonviral minicircle vector for deriving human iPS cells
-
F. Jia, K. D. Wilson, N. Sun et al., "A nonviral minicircle vector for deriving human iPS cells, " Nature Methods, vol. 7, pp. 197-199, 2010.
-
(2010)
Nature Methods
, vol.7
, pp. 197-199
-
-
Jia, F.1
Wilson, K.D.2
Sun, N.3
-
23
-
-
84866666977
-
Efficient generation of virus-free iPS cells using liposomal magnetofection
-
Article ID e45812
-
H. Y. Park, E. H. Noh, H.-M. Chung, M.-J. Kang, E. Y. Kim, and S. P. Park, "Efficient generation of virus-free iPS cells using liposomal magnetofection, " PLoS ONE, vol. 7, no. 9, Article ID e45812, 2012.
-
(2012)
PLoS ONE
, vol.7
, Issue.9
-
-
Park, H.Y.1
Noh, E.H.2
Chung, H.-M.3
Kang, M.-J.4
Kim, E.Y.5
Park, S.P.6
-
24
-
-
66049135249
-
Generation of induced pluripotent stem cells using recombinant proteins
-
H. Zhou, S. Wu, J. Y. Joo et al., "Generation of induced pluripotent stem cells using recombinant proteins, " Cell Stem Cell, vol. 4, no. 5, pp. 381-384, 2009.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.5
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Joo, J.Y.3
-
25
-
-
66049143859
-
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
-
D. Kim, C.-H. Kim, J.-I. Moon et al., "Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins, " Cell Stem Cell, vol. 4, no. 6, pp. 472-476, 2009.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.6
, pp. 472-476
-
-
Kim, D.1
Kim, C.-H.2
Moon, J.-I.3
-
26
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with syntheticmodifiedmRNA
-
L. Warren, P. D. Manos, T. Ahfeldt et al., "Highly efficient reprogramming to pluripotency and directed differentiation of human cells with syntheticmodifiedmRNA, " Cell Stem Cell, vol. 7, no. 5, pp. 618-630, 2010.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.5
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
-
27
-
-
84881256653
-
Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds
-
P. Hou, Y. Li, X. Zhang et al., "Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds, " Science, vol. 341, no. 6146, pp. 651-654, 2013.
-
(2013)
Science
, vol.341
, Issue.6146
, pp. 651-654
-
-
Hou, P.1
Li, Y.2
Zhang, X.3
-
28
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
N. Maherali, R. Sridharan, W. Xie et al., "Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution, " Cell Stem Cell, vol. 1, no. 1, pp. 55-70, 2007.
-
(2007)
Cell Stem Cell
, vol.1
, Issue.1
, pp. 55-70
-
-
Maherali, N.1
Sridharan, R.2
Xie, W.3
-
29
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
T. S. Mikkelsen, J. Hanna, X. Zhang et al., "Dissecting direct reprogramming through integrative genomic analysis, " Nature, vol. 454, no. 7200, pp. 49-55, 2008.
-
(2008)
Nature
, vol.454
, Issue.7200
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
-
30
-
-
58249085824
-
Role of the murine reprogramming factors in the induction of pluripotency
-
R. Sridharan, J. Tchieu, M. J. Mason et al., "Role of the murine reprogramming factors in the induction of pluripotency, " Cell, vol. 136, no. 2, pp. 364-377, 2009.
-
(2009)
Cell
, vol.136
, Issue.2
, pp. 364-377
-
-
Sridharan, R.1
Tchieu, J.2
Mason, M.J.3
-
31
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by smallmolecule compounds
-
D. Huangfu, R. Maehr, W. Guo et al., "Induction of pluripotent stem cells by defined factors is greatly improved by smallmolecule compounds, " Nature Biotechnology, vol. 26, no. 7, pp. 795-797, 2008.
-
(2008)
Nature Biotechnology
, vol.26
, Issue.7
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
-
32
-
-
54949115497
-
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
-
Y. Shi, C. Desponts, J. T. Do, H. S. Hahm, H. R. Schöler, and S. Ding, "Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds, " Cell Stem Cell, vol. 3, no. 5, pp. 568-574, 2008.
-
(2008)
Cell Stem Cell
, vol.3
, Issue.5
, pp. 568-574
-
-
Shi, Y.1
Desponts, C.2
Do, J.T.3
Hahm, H.S.4
Schöler, H.R.5
Ding, S.6
-
33
-
-
44349103591
-
A combined chemical and genetic approach for the generation of induced pluripotent stemcells
-
Y. Shi, J. T. Do, C. Desponts, H. S. Hahm, H. R. Schöler, and S. Ding, "A combined chemical and genetic approach for the generation of induced pluripotent stemcells, " Cell Stem Cell, vol. 2, pp. 525-528, 2008.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 525-528
-
-
Shi, Y.1
Do, J.T.2
Desponts, C.3
Hahm, H.S.4
Schöler, H.R.5
Ding, S.6
-
34
-
-
84871935467
-
Cellular reprogramming: A small molecule perspective
-
B. Nie, H. Wang, T. Laurent, and S. Ding, "Cellular reprogramming: a small molecule perspective, " Current Opinion in Cell Biology, vol. 24, no. 6, pp. 784-792, 2012.
-
(2012)
Current Opinion in Cell Biology
, vol.24
, Issue.6
, pp. 784-792
-
-
Nie, B.1
Wang, H.2
Laurent, T.3
Ding, S.4
-
35
-
-
73049086022
-
Generation of humaninduced pluripotent stem cells in the absence of exogenous Sox2
-
W. Li, H. Zhou, R. Abujarour et al., "Generation of humaninduced pluripotent stem cells in the absence of exogenous Sox2, " Stem Cells, vol. 27, no. 12, pp. 2992-3000, 2009.
-
(2009)
Stem Cells
, vol.27
, Issue.12
, pp. 2992-3000
-
-
Li, W.1
Zhou, H.2
Abujarour, R.3
-
36
-
-
77953809032
-
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells
-
R. D. Hawkins, G. C. Hon, L. K. Lee et al., "Distinct epigenomic landscapes of pluripotent and lineage-committed human cells, " Cell Stem Cell, vol. 6, no. 5, pp. 479-491, 2010.
-
(2010)
Cell Stem Cell
, vol.6
, Issue.5
, pp. 479-491
-
-
Hawkins, R.D.1
Hon, G.C.2
Lee, L.K.3
-
37
-
-
84878273239
-
Induction of pluripotency inmouse somatic cells with lineage specifiers
-
J. Shu, C. Wu, Y. Wu et al., "Induction of pluripotency inmouse somatic cells with lineage specifiers, " Cell, vol. 153, no. 5, pp. 963-975, 2013.
-
(2013)
Cell
, vol.153
, Issue.5
, pp. 963-975
-
-
Shu, J.1
Wu, C.2
Wu, Y.3
-
38
-
-
79961045254
-
T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications
-
F. Lluis, L. Ombrato, E. Pedone, S. Pepe, B. J. Merrill, and M. P. Cosma, "T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications, " Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 29, pp. 11912-11917, 2011.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.29
, pp. 11912-11917
-
-
Lluis, F.1
Ombrato, L.2
Pedone, E.3
Pepe, S.4
Merrill, B.J.5
Cosma, M.P.6
-
39
-
-
54949092372
-
From fibroblasts to iPS cells: Induced pluripotency by defined factors
-
R. Zhao and G. Q. Daley, "From fibroblasts to iPS cells: induced pluripotency by defined factors, " Journal of Cellular Biochemistry, vol. 105, no. 4, pp. 949-955, 2008.
-
(2008)
Journal of Cellular Biochemistry
, vol.105
, Issue.4
, pp. 949-955
-
-
Zhao, R.1
Daley, G.Q.2
-
40
-
-
80052451791
-
Wnt: What's Needed to maintain pluripotency?
-
H. Niwa, "Wnt: what's Needed to maintain pluripotency?" Nature Cell Biology, vol. 13, no. 9, pp. 1024-1026, 2011.
-
(2011)
Nature Cell Biology
, vol.13
, Issue.9
, pp. 1024-1026
-
-
Niwa, H.1
-
41
-
-
48149107133
-
Wnt signaling promotes reprogramming of somatic cells to pluripotency
-
A. Marson, R. Foreman, B. Chevalier et al., "Wnt signaling promotes reprogramming of somatic cells to pluripotency, " Cell Stem Cell, vol. 3, no. 2, pp. 132-135, 2008.
-
(2008)
Cell Stem Cell
, vol.3
, Issue.2
, pp. 132-135
-
-
Marson, A.1
Foreman, R.2
Chevalier, B.3
-
42
-
-
67049158201
-
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4
-
C. A. Lyssiotis, R. K. Foreman, J. Staerk et al., "Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4, " Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 22, pp. 8912-8917, 2009.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.22
, pp. 8912-8917
-
-
Lyssiotis, C.A.1
Foreman, R.K.2
Staerk, J.3
-
43
-
-
84877929153
-
Wnt signaling in stemand cancer stem cells
-
J. D. Holland, A. Klaus, A. N. Garratt, and W. Birchmeier, "Wnt signaling in stemand cancer stem cells, " Current Opinion in Cell Biology, vol. 25, no. 2, pp. 254-264, 2013.
-
(2013)
Current Opinion in Cell Biology
, vol.25
, Issue.2
, pp. 254-264
-
-
Holland, J.D.1
Klaus, A.2
Garratt, A.N.3
Birchmeier, W.4
-
44
-
-
54949136146
-
Two supporting factors greatly improve the efficiency of human iPSC generation
-
Y. Zhao, X. Yin, H. Qin et al., "Two supporting factors greatly improve the efficiency of human iPSC generation, " Cell Stem Cell, vol. 3, no. 5, pp. 475-479, 2008.
-
(2008)
Cell Stem Cell
, vol.3
, Issue.5
, pp. 475-479
-
-
Zhao, Y.1
Yin, X.2
Qin, H.3
-
45
-
-
69349100179
-
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
-
H. Hong, K. Takahashi, T. Ichisaka et al., "Suppression of induced pluripotent stem cell generation by the p53-p21 pathway, " Nature, vol. 460, no. 7259, pp. 1132-1135, 2009.
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1132-1135
-
-
Hong, H.1
Takahashi, K.2
Ichisaka, T.3
-
46
-
-
69349100455
-
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
-
T. Kawamura, J. Suzuki, Y. V. Wang et al., "Linking the p53 tumour suppressor pathway to somatic cell reprogramming, " Nature, vol. 460, no. 7259, pp. 1140-1144, 2009.
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1140-1144
-
-
Kawamura, T.1
Suzuki, J.2
Wang, Y.V.3
-
47
-
-
69349103956
-
The Ink4/Arf locus is a barrier for iPS cell reprogramming
-
H. Li, M. Collado, A. Villasante et al., "The Ink4/Arf locus is a barrier for iPS cell reprogramming, " Nature, vol. 460, no. 7259, pp. 1136-1139, 2009.
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1136-1139
-
-
Li, H.1
Collado, M.2
Villasante, A.3
-
48
-
-
69349098273
-
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
-
J. Utikal, J. M. Polo, M. Stadtfeld et al., "Immortalization eliminates a roadblock during cellular reprogramming into iPS cells, " Nature, vol. 460, no. 7259, pp. 1145-1148, 2009.
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1145-1148
-
-
Utikal, J.1
Polo, J.M.2
Stadtfeld, M.3
-
49
-
-
69349094006
-
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
-
R. M. Marión, K. Strati, H. Li et al., "A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity, " Nature, vol. 460, no. 7259, pp. 1149-1153, 2009.
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1149-1153
-
-
Marión, R.M.1
Strati, K.2
Li, H.3
-
50
-
-
69349098834
-
Stem cells: The promises and perils of p53
-
V. Krizhanovsky and S. W. Lowe, "Stem cells: the promises and perils of p53, " Nature, vol. 460, no. 7259, pp. 1085-1086, 2009.
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1085-1086
-
-
Krizhanovsky, V.1
Lowe, S.W.2
-
51
-
-
13944273471
-
P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
-
T. Lin, C. Chao, S. Saito et al., "p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression, " Nature Cell Biology, vol. 7, no. 2, pp. 165-171, 2005.
-
(2005)
Nature Cell Biology
, vol.7
, Issue.2
, pp. 165-171
-
-
Lin, T.1
Chao, C.2
Saito, S.3
-
52
-
-
84857710723
-
Stem cells: Flexible friends
-
N. Shevde, "Stem cells: flexible friends, " Nature, vol. 483, no. 7387, pp. S22-S26, 2012.
-
(2012)
Nature
, vol.483
, Issue.7387
, pp. S22-S26
-
-
Shevde, N.1
-
53
-
-
73049112178
-
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
-
M. A. Esteban, T. Wang, B. Qin et al., "Vitamin C enhances the generation of mouse and human induced pluripotent stem cells, " Cell Stem Cell, vol. 6, no. 1, pp. 71-79, 2010.
-
(2010)
Cell Stem Cell
, vol.6
, Issue.1
, pp. 71-79
-
-
Esteban, M.A.1
Wang, T.2
Qin, B.3
-
54
-
-
84856007232
-
The promise of induced pluripotent stem cells in research and therapy
-
D. A. Robinton and G. Q. Daley, "The promise of induced pluripotent stem cells in research and therapy, " Nature, vol. 481, no. 7381, pp. 295-305, 2012.
-
(2012)
Nature
, vol.481
, Issue.7381
, pp. 295-305
-
-
Robinton, D.A.1
Daley, G.Q.2
-
55
-
-
70349093119
-
Senescence impairs successful reprogramming to pluripotent stem cells
-
A. Banito, S. T. Rashid, J. C. Acosta et al., "Senescence impairs successful reprogramming to pluripotent stem cells, " Genes and Development, vol. 23, no. 18, pp. 2134-2139, 2009.
-
(2009)
Genes and Development
, vol.23
, Issue.18
, pp. 2134-2139
-
-
Banito, A.1
Rashid, S.T.2
Acosta, J.C.3
-
56
-
-
66249108601
-
Understanding the warburg effect: The metabolic requirements of cell proliferation
-
M. G. V. Heiden, L. C. Cantley, and C. B. Thompson, "Understanding the warburg effect: the metabolic requirements of cell proliferation, " Science, vol. 324, no. 5930, pp. 1029-1033, 2009.
-
(2009)
Science
, vol.324
, Issue.5930
, pp. 1029-1033
-
-
Heiden, M.G.V.1
Cantley, L.C.2
Thompson, C.B.3
-
57
-
-
69249210977
-
Hypoxia enhances the generation of induced pluripotent stem cells
-
Y. Yoshida, K. Takahashi, K. Okita, T. Ichisaka, and S. Yamanaka, "Hypoxia enhances the generation of induced pluripotent stem cells, " Cell Stem Cell, vol. 5, no. 3, pp. 237-241, 2009.
-
(2009)
Cell Stem Cell
, vol.5
, Issue.3
, pp. 237-241
-
-
Yoshida, Y.1
Takahashi, K.2
Okita, K.3
Ichisaka, T.4
Yamanaka, S.5
-
58
-
-
77951002352
-
The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells
-
A. Prigione, B. Fauler, R. Lurz, H. Lehrach, and J. Adjaye, "The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells, " Stem Cells, vol. 28, no. 4, pp. 721-733, 2010.
-
(2010)
Stem Cells
, vol.28
, Issue.4
, pp. 721-733
-
-
Prigione, A.1
Fauler, B.2
Lurz, R.3
Lehrach, H.4
Adjaye, J.5
-
59
-
-
78649647814
-
Reprogramming of human primary somatic cells by OCT4 and chemical compounds
-
S. Zhu, W. Li, H. Zhou et al., "Reprogramming of human primary somatic cells by OCT4 and chemical compounds, " Cell Stem Cell, vol. 7, no. 6, pp. 651-655, 2010.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.6
, pp. 651-655
-
-
Zhu, S.1
Li, W.2
Zhou, H.3
-
60
-
-
77957551870
-
Amesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
R. Li, J. Liang, S. Ni et al., "Amesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts, " Cell Stem Cell, vol. 7, no. 1, pp. 51-63, 2010.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.1
, pp. 51-63
-
-
Li, R.1
Liang, J.2
Ni, S.3
-
61
-
-
77956320116
-
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
-
P. Samavarchi-Tehrani, A. Golipour, L. David et al., "Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming, " Cell Stem Cell, vol. 7, no. 1, pp. 64-77, 2010.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.1
, pp. 64-77
-
-
Samavarchi-Tehrani, P.1
Golipour, A.2
David, L.3
-
62
-
-
70350732790
-
A chemical platformfor improved induction of human iPSCs
-
T. Lin, R. Ambasudhan, X. Yuan et al., "A chemical platformfor improved induction of human iPSCs, " Nature Methods, vol. 6, no. 11, pp. 805-808, 2009.
-
(2009)
Nature Methods
, vol.6
, Issue.11
, pp. 805-808
-
-
Lin, T.1
Ambasudhan, R.2
Yuan, X.3
-
63
-
-
70350536767
-
A small-molecule inhibitor of tgf-β signaling replaces sox2 in reprogramming by inducing Nanog
-
J. K. Ichida, J. Blanchard, K. Lam et al., "A small-molecule inhibitor of tgf-β signaling replaces sox2 in reprogramming by inducing Nanog, " Cell Stem Cell, vol. 5, no. 5, pp. 491-503, 2009.
-
(2009)
Cell Stem Cell
, vol.5
, Issue.5
, pp. 491-503
-
-
Ichida, J.K.1
Blanchard, J.2
Lam, K.3
-
64
-
-
79953001876
-
Brief report: Combined chemical treatment enables Oct4-induced reprogramming frommouse embryonic fibroblasts
-
X. Yuan, H. Wan, X. Zhao, S. Zhu, Q. Zhou, and S. Ding, "Brief report: combined chemical treatment enables Oct4-induced reprogramming frommouse embryonic fibroblasts, " StemCells, vol. 29, no. 3, pp. 549-553, 2011.
-
(2011)
StemCells
, vol.29
, Issue.3
, pp. 549-553
-
-
Yuan, X.1
Wan, H.2
Zhao, X.3
Zhu, S.4
Zhou, Q.5
Ding, S.6
-
65
-
-
84919666195
-
Identification of a small molecule that turns on the pluripotency gene circuitry in human fibroblasts
-
G. N. Pandian, S. Sato, C. Anandhakumar et al., "Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts, " ACS Chemical Biology, vol. 9, no. 12, pp. 2729-2736, 2014.
-
(2014)
ACS Chemical Biology
, vol.9
, Issue.12
, pp. 2729-2736
-
-
Pandian, G.N.1
Sato, S.2
Anandhakumar, C.3
-
66
-
-
77950965653
-
Butyrate greatly enhances derivation of human induced pluripotent stemcells by promoting epigenetic remodeling and the expression of pluripotencyassociated genes
-
P. Mali, B.-K. Chou, J. Yen et al., "Butyrate greatly enhances derivation of human induced pluripotent stemcells by promoting epigenetic remodeling and the expression of pluripotencyassociated genes, " Stem Cells, vol. 28, no. 4, pp. 713-720, 2010.
-
(2010)
Stem Cells
, vol.28
, Issue.4
, pp. 713-720
-
-
Mali, P.1
Chou, B.-K.2
Yen, J.3
-
67
-
-
84870586551
-
A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells
-
J. Lee, Y. Xia, M.-Y. Son et al., "A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells, " Angewandte Chemie International Edition, vol. 51, no. 50, pp. 12509-12513, 2012.
-
(2012)
Angewandte Chemie International Edition
, vol.51
, Issue.50
, pp. 12509-12513
-
-
Lee, J.1
Xia, Y.2
Son, M.-Y.3
-
68
-
-
80053633785
-
Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells
-
Q. Wang, X. Xu, J. Li et al., "Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells, " Cell Research, vol. 21, no. 10, pp. 1424-1435, 2011.
-
(2011)
Cell Research
, vol.21
, Issue.10
, pp. 1424-1435
-
-
Wang, Q.1
Xu, X.2
Li, J.3
-
69
-
-
67650451121
-
ROCKinhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells
-
D. A. Claassen, M. M. Desler, and A. Rizzino, "ROCKinhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells, " Molecular Reproduction and Development, vol. 76, no. 8, pp. 722-732, 2009.
-
(2009)
Molecular Reproduction and Development
, vol.76
, Issue.8
, pp. 722-732
-
-
Claassen, D.A.1
Desler, M.M.2
Rizzino, A.3
-
70
-
-
84866992567
-
A kinase inhibitor screen identifies smallmolecule enhancers of reprogramming and iPS cell generation
-
article 1085
-
Z. Li and T. M. Rana, "A kinase inhibitor screen identifies smallmolecule enhancers of reprogramming and iPS cell generation, " Nature Communications, vol. 3, article 1085, 2012.
-
(2012)
Nature Communications
, vol.3
-
-
Li, Z.1
Rana, T.M.2
-
71
-
-
80052819789
-
Rapamycin and other longevitypromoting compounds enhance the generation of mouse induced pluripotent stem cells
-
T. Chen, L. Shen, J. Yu et al., "Rapamycin and other longevitypromoting compounds enhance the generation of mouse induced pluripotent stem cells, " Aging Cell, vol. 10, no. 5, pp. 908-911, 2011.
-
(2011)
Aging Cell
, vol.10
, Issue.5
, pp. 908-911
-
-
Chen, T.1
Shen, L.2
Yu, J.3
-
72
-
-
38349022657
-
Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma
-
Y. Shi, M. Zou, E. Y. Baitei et al., "Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma, " Cancer Gene Therapy, vol. 15, no. 2, pp. 101-107, 2008.
-
(2008)
Cancer Gene Therapy
, vol.15
, Issue.2
, pp. 101-107
-
-
Shi, Y.1
Zou, M.2
Baitei, E.Y.3
-
73
-
-
78650915547
-
Generation of iPSCs frommouse fibroblasts with a single gene, Oct4, and small molecules
-
Y. Li, Q. Zhang, X. Yin et al., "Generation of iPSCs frommouse fibroblasts with a single gene, Oct4, and small molecules, " Cell Research, vol. 21, no. 1, pp. 196-204, 2011.
-
(2011)
Cell Research
, vol.21
, Issue.1
, pp. 196-204
-
-
Li, Y.1
Zhang, Q.2
Yin, X.3
-
74
-
-
79958293319
-
Pan-src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells
-
J. Staerk, C. A. Lyssiotis, L. A. Medeiro et al., "Pan-src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells, " Angewandte Chemie-International Edition, vol. 50, no. 25, pp. 5734-5736, 2011.
-
(2011)
Angewandte Chemie-International Edition
, vol.50
, Issue.25
, pp. 5734-5736
-
-
Staerk, J.1
Lyssiotis, C.A.2
Medeiro, L.A.3
-
75
-
-
80052437236
-
Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1
-
J.-H. Moon, J. S. Heo, J. S. Kim et al., "Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1, " Cell Research, vol. 21, no. 9, pp. 1305-1315, 2011.
-
(2011)
Cell Research
, vol.21
, Issue.9
, pp. 1305-1315
-
-
Moon, J.-H.1
Heo, J.S.2
Kim, J.S.3
-
76
-
-
84900397721
-
Reprogram or reboot: Small molecule approaches for the production of induced pluripotent stem cells and direct cell reprogramming
-
D.-W. Jung, W.-H. Kim, and D. R. Williams, "Reprogram or reboot: small molecule approaches for the production of induced pluripotent stem cells and direct cell reprogramming, " ACS Chemical Biology, vol. 9, no. 1, pp. 80-95, 2014.
-
(2014)
ACS Chemical Biology
, vol.9
, Issue.1
, pp. 80-95
-
-
Jung, D.-W.1
Kim, W.-H.2
Williams, D.R.3
-
77
-
-
80051728762
-
Efficient non-viral reprogramming of myoblasts to stemness with a single small molecule to generate cardiac progenitor cells
-
Article ID e23667
-
Z. Pasha, H. K. Haider, and M. Ashraf, "Efficient non-viral reprogramming of myoblasts to stemness with a single small molecule to generate cardiac progenitor cells, " PLoS ONE, vol. 6, no. 8, Article ID e23667, 2011.
-
(2011)
PLoS ONE
, vol.6
, Issue.8
-
-
Pasha, Z.1
Haider, H.K.2
Ashraf, M.3
-
78
-
-
80052743286
-
Patient-specific pluripotent stem cells in neurological diseases
-
Article ID 212487, 17 pages
-
S. Durnaoglu, S. Genc, and K. Genc, "Patient-specific pluripotent stem cells in neurological diseases, " Stem Cells International, vol. 2011, Article ID 212487, 17 pages, 2011.
-
(2011)
Stem Cells International
, vol.2011
-
-
Durnaoglu, S.1
Genc, S.2
Genc, K.3
-
79
-
-
84859514692
-
Asmall molecule mimicking a phosphatidylinositol (4, 5)-bisphosphate binding pleckstrin homology domain
-
L. H. Mak, S. N. Georgiades, E. Rosivatz et al., "Asmall molecule mimicking a phosphatidylinositol (4, 5)-bisphosphate binding pleckstrin homology domain, " ACS Chemical Biology, vol. 6, no. 12, pp. 1382-1390, 2011.
-
(2011)
ACS Chemical Biology
, vol.6
, Issue.12
, pp. 1382-1390
-
-
Mak, L.H.1
Georgiades, S.N.2
Rosivatz, E.3
-
80
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Q.-L. Ying, J. Wray, J. Nichols et al., "The ground state of embryonic stem cell self-renewal, " Nature, vol. 453, no. 7194, pp. 519-523, 2008.
-
(2008)
Nature
, vol.453
, Issue.7194
, pp. 519-523
-
-
Ying, Q.-L.1
Wray, J.2
Nichols, J.3
-
81
-
-
84896093612
-
Platform for induction and maintenance of transgene-free hiPSCs resembling ground state pluripotent stemcells
-
B. Valamehr, M. Robinson, R. Abujarour et al., "Platform for induction and maintenance of transgene-free hiPSCs resembling ground state pluripotent stemcells, " StemCell Reports, vol. 2, no. 3, pp. 366-381, 2014.
-
(2014)
StemCell Reports
, vol.2
, Issue.3
, pp. 366-381
-
-
Valamehr, B.1
Robinson, M.2
Abujarour, R.3
|