Identification of a small molecule that turns on the pluripotency gene circuitry in human fibroblasts

ACS Chemical Biology

Volumn 9, Issue 12, 2014, Pages 2729-2736

  Pandian, Ganesh N ^a   Sato, Shinsuke ^a   Anandhakumar, Chandran ^b   Taniguchi, Junichi ^b   Takashima, Kazuhiro ^b   Syed, Junetha ^b   Han, Le ^b,c   Saha, Abhijit ^f   Bando, Toshikazu ^f   Nagase, Hiroki ^d,e   Sugiyama, Hiroshi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e CHIBA CANCER CENTER   (Japan)

^f NONE

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; POLYAMIDE; PYRROLE; BIOLOGICAL MARKER; CHROMATIN; MOLECULAR LIBRARY; NYLON; OCTAMER TRANSCRIPTION FACTOR 4; POU5F1 PROTEIN, MOUSE; PYRROLE DERIVATIVE; SAHA-PIP-DELTA;

ARTICLE; CONTROLLED STUDY; FIBROBLAST; GENE; GENE EXPRESSION; HUMAN; MOLECULE; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; SOMATIC CELL; TRANSCRIPTION INITIATION; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CHEMICAL STRUCTURE; CHROMATIN; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETIC EPIGENESIS; GENETICS; METABOLISM; MOLECULAR LIBRARY; MOUSE; PHARMACOLOGY; SYNTHESIS;

ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELLS, CULTURED; CELLULAR REPROGRAMMING; CHROMATIN; EPIGENESIS, GENETIC; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HISTONE DEACETYLASE INHIBITORS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MOLECULAR STRUCTURE; NYLONS; OCTAMER TRANSCRIPTION FACTOR-3; PYRROLES; SMALL MOLECULE LIBRARIES;

EID: 84919666195     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500724t     Document Type: Article

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