Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate

eLife

Volumn 2015, Issue 4, 2015, Pages

  Schotten, Sebastiaan ^a   Meijer, Marieke ^a   Walter, Alexander M ^a,b,c   Huson, Vincent ^a   Mamer, Lauren ^d   Kalogreades, Lawrence ^a   Ter Veer, Mirelle ^a   Ruiter, Marvin ^a   Brose, Nils ^e   Rosenmund, Christian ^d   Sørensen, Jakob B ^b   Verhage, Matthijs ^a   Cornelisse, L Niels ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SYNAPTOBREVIN; SYNTAXIN; CALCIUM; COMPLEXIN I; COMPLEXIN II; NERVE PROTEIN; PHORBOL ESTER; SUCROSE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CALCIUM BINDING; CALCIUM TRANSPORT; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MEMBRANE FUSION; MOUSE; NERVE CELL NETWORK; NERVE STIMULATION; NEUROTRANSMITTER RELEASE; NONHUMAN; PROTEIN MODIFICATION; REGULATORY MECHANISM; SIMULATION; SYNAPSE VESICLE; SYNAPTIC EFFICACY; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP TECHNIQUE; ANIMAL; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HIPPOCAMPUS; KINETICS; METABOLISM; NERVE CELL; OSMOLARITY; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; PRIMARY CELL CULTURE; SYNAPSE; THERMODYNAMICS; TRANSPORT AT THE CELLULAR LEVEL;

ACTION POTENTIALS; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; BIOLOGICAL TRANSPORT; CALCIUM; GENE EXPRESSION; HIPPOCAMPUS; KINETICS; MEMBRANE FUSION; MICE; NERVE TISSUE PROTEINS; NEURONS; OSMOLAR CONCENTRATION; PATCH-CLAMP TECHNIQUES; PHORBOL ESTERS; PRIMARY CELL CULTURE; SUCROSE; SYNAPSES; SYNAPTIC TRANSMISSION; SYNAPTIC VESICLES; THERMODYNAMICS;

EID: 84928141312     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.05531     Document Type: Article

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