Spontaneous resolution of acute rejection and tolerance induction with IL-2 fusion protein in vascularized composite allotransplantation

American Journal of Transplantation

Volumn 15, Issue 5, 2015, Pages 1231-1240

  Jindal, R ^a   Unadkat, J ^a   Zhang, W ^a   Zhang, D ^b   Ng, T W ^a   Wang, Y ^c   Jiang, J ^c   Lakkis, F ^a   Rubin, P ^a   Lee, W P A ^d   Gorantla, V S ^a   Zheng, X X ^c  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c TONGJI UNIVERSITY   (China)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

basic (laboratory) research science; calcineurin inhibitor: cyclosporine A (CsA); fusion proteins and monoclonal antibodies: T cell specific; immune regulation; immunosuppressant; immunosuppression immune modulation; immunosuppressive regimens; minimization withdrawal; tolerance; translational research science; vascularized composite and reconstructive transplantation

Indexed keywords

ANTIGEN; CYCLOSPORIN A; GAMMA INTERFERON; GZMB PROTEIN; INTERLEUKIN 2; INTERLEUKIN 2 FUSION PROTEIN; LYMPHOCYTE ANTIBODY; PRF1 PROTEIN; PROTEIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; CYCLOSPORIN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, RAT; GRANZYME; GZMB PROTEIN, RAT; HYBRID PROTEIN; PERFORIN, RAT; PORE FORMING CYTOTOXIC PROTEIN;

ACUTE GRAFT REJECTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DONOR; DOSE RESPONSE; EFFECTOR CELL; GENE EXPRESSION; GRAFT SURVIVAL; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IMMUNOSTIMULATION; IMMUNOSUPPRESSIVE TREATMENT; IN VIVO STUDY; LIMB; LONG TERM SURVIVAL; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY T LYMPHOCYTE; SKIN BIOPSY; SURVIVOR; TREATMENT DURATION; TREATMENT OUTCOME; VASCULARIZED COMPOSITE ALLOTRANSPLANTATION; ALLOTRANSPLANTATION; ANIMAL; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GRAFT REJECTION; HINDLIMB; HUMAN; IMMUNE SYSTEM; LEWIS RAT; METABOLISM; PROCEDURES; TRANSPLANTATION; TRANSPLANTATION TOLERANCE; WISTAR RAT;

ANIMALS; CELL PROLIFERATION; CYCLOSPORINE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GRAFT REJECTION; GRAFT SURVIVAL; GRANZYMES; HINDLIMB; HUMANS; IMMUNE SYSTEM; IMMUNE TOLERANCE; INTERLEUKIN-2; MALE; PORE FORMING CYTOTOXIC PROTEINS; RATS; RATS, INBRED LEW; RATS, WISTAR; RECOMBINANT FUSION PROTEINS; TRANSPLANTATION TOLERANCE; TRANSPLANTATION, HOMOLOGOUS; VASCULARIZED COMPOSITE ALLOTRANSPLANTATION;

EID: 84928054103     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.13118     Document Type: Article

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