Composite tissue vasculopathy and degeneration following multiple episodes of acute rejection in reconstructive transplantation

American Journal of Transplantation

Volumn 10, Issue 2, 2010, Pages 251-261

  Unadkat, J V ^a   Schneeberger, S ^a   Horibe, E H ^a   Goldbach, C ^b   Solari, M G ^a   Washington, K M ^a   Gorantla, V S ^a   Cooper, G M ^c   Thomson, A W ^a   Andrew Lee, W P ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic allograft dysfunction; Chronic allograft rejection; Chronic graft deterioration; Chronic rejection; Composite tissue allograft; Composite tissue transplantation; Face transplantation; Graft fibrosis; Graft vessel disease; Hand transplant

Indexed keywords

CYCLOSPORIN A; DEXAMETHASONE;

ACUTE GRAFT REJECTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN NORWAY RAT; CELL INFILTRATION; COMPARATIVE STUDY; COMPOSITE GRAFT; COMPOSITE TISSUE VASCULOPATHY; COMPOSITE TISSUE VASCULOPATHY DEGENERATION; CONTROLLED STUDY; EXPERIMENTAL MODEL; FIBROSIS; FRACTURE NONUNION; GENE EXPRESSION; HINDLIMB; IMMUNOSUPPRESSIVE TREATMENT; ISOGRAFT; LEWIS RAT; MACROPHAGE; MALE; MUSCLE ATROPHY; NONHUMAN; OSTEOSCLEROSIS; PRIORITY JOURNAL; RAT; SKIN ATROPHY; TISSUE SPECIFICITY; UPREGULATION; VASCULAR DISEASE; VASCULAR LESION;

ANIMALS; CYCLOSPORINE; HINDLIMB; MALE; RATS; RATS, INBRED BN; RATS, INBRED LEW; SPECIFIC PATHOGEN-FREE ORGANISMS; TRANSPLANTATION, ISOGENEIC;

EID: 75149140435     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2009.02941.x     Document Type: Article

References (29)

1. Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RD, Chapman JR. The natural history of chronic allograft nephropathy. N Engl J Med 2003 349 : 2326 2333.
2. Libby P, Pober JS. Chronic rejection. Immunity 2001 14 : 387 397.
3. Kouwenhoven EA, IJzermans JN, de Bruin RW. Etiology and pathophysiology of chronic transplant dysfunction. Transpl Int 2000 13 : 385 401.
4. Lanzetta M, Petruzzo P, Dubernard JM et al. Second report (1998-2006) of the International Registry of Hand and Composite Tissue Transplantation. Transpl Immunol 2007 18 : 1 6.
5. Akioka K, Takahara S, Ichikawa S, Yoshimura N, Akiyama T, Ohshima S. Factors predicting long-term graft survival after kidney transplantation: multicenter study in Japan. World J Surg 2005 29 : 249 256.
6. Lindholm A, Ohlman S, Albrechtsen D, Tufveson G, Persson H, Persson NH. The impact of acute rejection episodes on long-term graft function and outcome in 1347 primary renal transplants treated by 3 cyclosporine regimens. Transplantation 1993 56 : 307 315.
7. Basadonna GP, Matas AJ, Gillingham KJ et al. Early versus late acute renal allograft rejection: Impact on chronic rejection. Transplantation 1993 55 : 993 995.
8. Matas AJ, Gillingham KJ, Payne WD, Najarian JS. The impact of an acute rejection episode on long-term renal allograft survival (t1/2). Transplantation 1994 57 : 857 859.
9. Nguyen VT, Taieb A, Sacks JM et al. Allopeptide-pulsed dendritic cells and composite tissue allograft survival. Microsurgery 2007 27 : 105 111.
10. Buttemeyer R, Jones NF, Min Z, Rao U. Rejection of the component tissues of limb allografts in rats immunosuppressed with FK-506 and cyclosporine. Plast Reconstr Surg 1996 97 : 139 148 discussion 149-151. (Pubitemid 126425836)
11. Schneeberger S, Kreczy A, Brandacher G, Steurer W, Margreiter R. Steroid- and ATG-resistant rejection after double forearm transplantation responds to Campath-1H. Am J Transplant 2004 4 : 1372 1374.
12. Dubernard JM, Lengele B, Morelon E et al. Outcomes 18 months after the first human partial face transplantation. N Engl J Med 2007 357 : 2451 2460.
13. Breidenbach WRK, Buell J, Blair B, Kaufman C. Update on the American hand transplant experience: five hand transplants performed in Louisville. Am J Transplant 2009 9 (Suppl. 2 317.
14. White E, Hildemann WH. Allografts in genetically defined rats: difference in survival between kidney and skin. Science 1968 162 : 1293 1295.
15. Brook MO, Wood KJ, Jones ND. The impact of memory T cells on rejection and the induction of tolerance. Transplantation 2006 82 : 1 9.
16. Nadeau KC, Azuma H, Tilney NL. Sequential cytokine dynamics in chronic rejection of rat renal allografts: Roles for cytokines RANTES and MCP-1. Proc Natl Acad Sci USA 1995 92 : 8729 8733.
17. Cailhier JF, Laplante P, Hebert MJ. Endothelial apoptosis and chronic transplant vasculopathy: Recent results, novel mechanisms. Am J Transplant 2006 6 : 247 253.
18. Choi J, Enis DR, Koh KP, Shiao SL, Pober JS. T lymphocyte-endothelial cell interactions. Annu Rev Immunol 2004 22 : 683 709.
19. Pober JS, Kluger MS, Schechner JS. Human endothelial cell presentation of antigen and the homing of memory/effector T cells to skin. Ann NY Acad Sci 2001 941 : 12 25.
20. Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 1993 362 : 801 809.
21. Lee WP, Yaremchuk MJ, Pan YC, Randolph MA, Tan CM, Weiland AJ. Relative antigenicity of components of a vascularized limb allograft. Plast Reconstr Surg 1991 87 : 401 411.
22. Russell ME, Wallace AF, Hancock WW et al. Upregulation of cytokines associated with macrophage activation in the Lewis-to-F344 rat transplantation model of chronic cardiac rejection. Transplantation 1995 59 : 572 578.
23. Armstrong AT, Strauch AR, Starling RC, Sedmak DD, Orosz CG. Morphometric analysis of neointimal formation in murine cardiac grafts: III. Dissociation of intestitial fibrosis from neointimal formation. Transplantation 1997 64 : 1198 1202.
24. Utvag SE, Reikeras O. Effects of nail rigidity on fracture healing. Strength and mineralisation in rat femoral bone. Arch Orthop Trauma Surg 1998 118 : 7 13.
25. Jevon M, Sabokbar A, Fujikawa Y et al. Gender- and age-related differences in osteoclast formation from circulating precursors. J Endocrinol 2002 172 : 673 681.
26. Del Fattore A, Cappariello A, Teti A. Genetics, pathogenesis and complications of osteopetrosis. Bone 2008 42 : 19 29.
27. Tolar J, Teitelbaum SL, Orchard PJ. Osteopetrosis. N Engl J Med 2004 351 : 2839 2849.
28. Stewart S, Fishbein MC, Snell GI et al. Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection. J Heart Lung Transplant 2007 26 : 1229 1242. (Pubitemid 350256994)
29. Unadkat JV SS, Solari MG, Washington K, Zheng XX, Lee WPA. Transplant vasculopathy and humoral alloresponse in composite tissue allotransplantation: Role of multiple acute rejections. Am J Transplant 2009 9 : 315.