IL-2 receptor-targeted cytolytic IL-2/Fc fusion protein treatment blocks diabetogenic autoimmunity in nonobese diabetic mice

Journal of Immunology

Volumn 163, Issue 7, 1999, Pages 4041-4048

  Zheng, Xin Xiao ^a   Steele, Alan W ^a   Hancock, Wayne W ^b   Kawamoto, Kensaku ^a   Li, Xian Chang ^a   Nickerson, Peter W ^a   Li, Yongsheng ^a   Tian, Yan ^a   Strom, Terry B ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN FC FRAGMENT; INTERLEUKIN 2 RECEPTOR;

ALLOIMMUNITY; ALPHA CHAIN; ANIMAL CELL; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ARTICLE; AUTOIMMUNITY; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DIABETOGENESIS; IMMUNOGENICITY; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; BLOTTING, WESTERN; CD4 LYMPHOCYTE COUNT; CYTOTOXICITY, IMMUNOLOGIC; DIABETES MELLITUS, TYPE 1; FEMALE; GENE TARGETING; GENE THERAPY; HALF-LIFE; IMMUNOGLOBULIN FC FRAGMENTS; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-2; LYMPHOCYTE DEPLETION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED NOD; RECEPTORS, INTERLEUKIN-2; RECOMBINANT FUSION PROTEINS;

EID: 0344069729     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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