Noise-induced cochlear F-actin depolymerization is mediated via ROCK2/p-ERM signaling

Journal of Neurochemistry

Volumn 133, Issue 5, 2015, Pages 617-628

  Han, Yu ^a,b   Wang, Xianren ^a   Chen, Jun ^a   Sha, Su Hua ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

actin cytoskeleton; noise induced hearing loss; radixin siRNA; rho associated kinases; ROCK2 siRNA

Indexed keywords

EZRIN RADIXIN MOESIN; F ACTIN; G ACTIN; ISOPROTEIN; LYSOPHOSPHATIDIC ACID; RADIXIN; REGULATOR PROTEIN; RHO KINASE; ROCK2 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ACTIN; CYTOSKELETON PROTEIN; DNA BINDING PROTEIN; ETV5 PROTEIN, MOUSE; LYSOPHOSPHOLIPID; MEMBRANE PROTEIN; ROCK2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ACTIN FILAMENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY SYSTEM PARAMETERS; CELL LOSS; COCHLEA; CONTROLLED STUDY; DEPOLYMERIZATION; DISEASE EXACERBATION; DOWN REGULATION; ENZYME ACTIVATION; HEARING IMPAIRMENT; MALE; MOUSE; NOISE; NONHUMAN; OUTER HAIR CELL; PERMANENT THRESHOLD SHIFT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TEMPORARY THRESHOLD SHIFT; UPREGULATION; ANIMAL; CBA MOUSE; DRUG EFFECTS; EVOKED BRAIN STEM AUDITORY RESPONSE; GENE SILENCING; GENETICS; HAIR CELL; INJURIES; METABOLISM; NOISE INJURY; PATHOLOGY; PHYSIOLOGY;

MUS;

ACTINS; ANIMALS; COCHLEA; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GENE SILENCING; HAIR CELLS, AUDITORY, OUTER; HEARING LOSS, NOISE-INDUCED; LYSOPHOSPHOLIPIDS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED CBA; RHO-ASSOCIATED KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84928014571     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13061     Document Type: Article

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