메뉴 건너뛰기




Volumn 25, Issue 8, 2014, Pages 750-757

Δ9-Tetrahydrocannabinol-like discriminative stimulus effects of compounds commonly found in K2/Spice

Author keywords

Abuse liability; Cannabinoids; Drug discrimination; Locomotor activity; Mouse; Rat

Indexed keywords

1 (5 FLUOROPENTYL) 3 (1 NAPHTHOYL)INDOLE; 1 BUTYL 3 (1 NAPHTHOYL)INDOLE; 3 (1 NAPHTHOYL) 1 PENTYLINDOLE; CANNABINOID RECEPTOR AGONIST; CP 47,497 C8 HOMOLOG; DRONABINOL; JWH 200; JWH 203; JWH 250; UNCLASSIFIED DRUG; CP 47497; CYCLOHEXANOL DERIVATIVE; INDOLE DERIVATIVE; JWH-073; NAPHTHALENE DERIVATIVE;

EID: 84927940122     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0000000000000093     Document Type: Article
Times cited : (38)

References (33)
  • 1
    • 77952664328 scopus 로고    scopus 로고
    • JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist
    • Atwood BK, Huffman J, Straiker A, Mackie K (2010). JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist. Br J Pharmacol 160:585-593.
    • (2010) Br J Pharmacol , vol.160 , pp. 585-593
    • Atwood, B.K.1    Huffman, J.2    Straiker, A.3    Mackie, K.4
  • 2
    • 79955928510 scopus 로고    scopus 로고
    • CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists
    • Atwood BK, Lee D, Straiker A, Widlanski TS, Mackie K (2011). CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. Eur J Pharmacol 659:139-145.
    • (2011) Eur J Pharmacol , vol.659 , pp. 139-145
    • Atwood, B.K.1    Lee, D.2    Straiker, A.3    Widlanski, T.S.4    Mackie, K.5
  • 4
    • 0026409374 scopus 로고
    • Drug abuse potential evaluation in animals
    • Balster RL (1991). Drug abuse potential evaluation in animals. Br J Addict 86:1549-1558.
    • (1991) Br J Addict , vol.86 , pp. 1549-1558
    • Balster, R.L.1
  • 5
    • 84857372061 scopus 로고    scopus 로고
    • Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity
    • Brents LK, Gallus-Zawada A, Radominska-Pandya A, Vasiljevik T, Prisinzano TE, Fantegrossi WE, et al. (2012). Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. Biochem Pharmacol 83:952-961.
    • (2012) Biochem Pharmacol , vol.83 , pp. 952-961
    • Brents, L.K.1    Gallus-Zawada, A.2    Radominska-Pandya, A.3    Vasiljevik, T.4    Prisinzano, T.E.5    Fantegrossi, W.E.6    Al, E.7
  • 6
    • 84882433884 scopus 로고    scopus 로고
    • Differential drug-drug interactions of the synthetic Cannabinoids JWH-018 and JWH-073: Implications for drug abuse liability and pain therapy
    • Brents LK, Zimmerman SM, Saffell AR, Prather PL, Fantegrossi WE (2013). Differential drug-drug interactions of the synthetic Cannabinoids JWH-018 and JWH-073: implications for drug abuse liability and pain therapy. J Pharmacol Exp Ther 346:350-361.
    • (2013) J Pharmacol Exp Ther , vol.346 , pp. 350-361
    • Brents, L.K.1    Zimmerman, S.M.2    Saffell, A.R.3    Prather, P.L.4    Fantegrossi, W.E.5
  • 7
    • 70449420106 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction
    • Carroll FI, Blough BE, Abraham P, Mills AC, Holleman JA, Wolckenhauer SA, et al. (2009). Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction. J Med Chem 52:6768-6781.
    • (2009) J Med Chem , vol.52 , pp. 6768-6781
    • Carroll, F.I.1    Blough, B.E.2    Abraham, P.3    Mills, A.C.4    Holleman, J.A.5    Wolckenhauer, S.A.6
  • 8
    • 84857335499 scopus 로고    scopus 로고
    • Sex differences in cannabinoid 1 vs. Cannabinoid 2 receptor-selective antagonism of antinociception produced by delta9-tetrahydrocannabinol and CP55,940 in the rat
    • Craft RM, Wakley AA, Tsutsui KT, Laggart JD (2012). Sex differences in cannabinoid 1 vs. cannabinoid 2 receptor-selective antagonism of antinociception produced by delta9-tetrahydrocannabinol and CP55,940 in the rat. J Pharmacol Exp Ther 340:787-800.
    • (2012) J Pharmacol Exp Ther , vol.340 , pp. 787-800
    • Craft, R.M.1    Wakley, A.A.2    Tsutsui, K.T.3    Laggart, J.D.4
  • 9
    • 84873637445 scopus 로고    scopus 로고
    • Identification and structural elucidation of four cannabimimetic compounds (RCS-4, AM-2201, JWH-203 and JWH-210) in seized products
    • Denooz R, Vanheugen JC, Frederich M, de Tullio P, Charlier C (2013). Identification and structural elucidation of four cannabimimetic compounds (RCS-4, AM-2201, JWH-203 and JWH-210) in seized products. J Anal Toxicol 37:56-63.
    • (2013) J Anal Toxicol , vol.37 , pp. 56-63
    • Denooz, R.1    Vanheugen, J.C.2    Frederich, M.3    De Tullio, P.4    Charlier, C.5
  • 10
    • 84855507862 scopus 로고    scopus 로고
    • Beyond THC: The New Generation of Cannabinoid Designer Drugs
    • Fattore L, Fratta W (2011). Beyond THC: The New Generation of Cannabinoid Designer Drugs. Front Behav Neurosci 5:60.
    • (2011) Front Behav Neurosci , vol.5 , pp. 60
    • Fattore, L.1    Fratta, W.2
  • 12
    • 84881553576 scopus 로고    scopus 로고
    • Locomotor stimulant and discriminative stimulus effects of 'bath salt' cathinones
    • Gatch MB, Taylor CM, Forster MJ (2013). Locomotor stimulant and discriminative stimulus effects of 'bath salt' cathinones. Behav Pharmacol 24:437-447.
    • (2013) Behav Pharmacol , vol.24 , pp. 437-447
    • Gatch, M.B.1    Taylor, C.M.2    Forster, M.J.3
  • 13
    • 84055219353 scopus 로고    scopus 로고
    • JWH-018 and JWH-073: δ9-tetrahydrocannabinol-like discriminative stimulus effects in monkeys
    • Ginsburg BC, Schulze DR, Hruba L, McMahon LR (2012). JWH-018 and JWH-073: δ9-tetrahydrocannabinol-like discriminative stimulus effects in monkeys. J Pharmacol Exp Ther 340:37-45.
    • (2012) J Pharmacol Exp Ther , vol.340 , pp. 37-45
    • Ginsburg, B.C.1    Schulze, D.R.2    Hruba, L.3    McMahon, L.R.4
  • 14
    • 84862768861 scopus 로고    scopus 로고
    • "spice" and "k2" herbal highs: A case series and systematic review of the clinical effects and biopsychosocial implications of synthetic cannabinoid use in humans
    • Gunderson EW, Haughey HM, Ait-Daoud N, Joshi AS, Hart CL (2012). "Spice" and "K2" herbal highs: a case series and systematic review of the clinical effects and biopsychosocial implications of synthetic cannabinoid use in humans. Am J Addict 21:320-326.
    • (2012) Am J Addict , vol.21 , pp. 320-326
    • Gunderson, E.W.1    Haughey, H.M.2    Ait-Daoud, N.3    Joshi, A.S.4    Hart, C.L.5
  • 16
    • 84881542259 scopus 로고    scopus 로고
    • A translational pharmacology approach to understanding the predictive value of abuse potential assessments
    • Horton DB, Potter DM, Mead AN (2013). A translational pharmacology approach to understanding the predictive value of abuse potential assessments. Behav Pharmacol 24:410-436.
    • (2013) Behav Pharmacol , vol.24 , pp. 410-436
    • Horton, D.B.1    Potter, D.M.2    Mead, A.N.3
  • 17
    • 84865159568 scopus 로고    scopus 로고
    • Apparent inverse relationship between cannabinoid agonist efficacy and tolerance/cross-tolerance produced by δ9-tetrahydrocannabinol treatment in rhesus monkeys
    • Hruba L, Ginsburg B, McMahon LR (2012). Apparent inverse relationship between cannabinoid agonist efficacy and tolerance/cross-tolerance produced by δ9-tetrahydrocannabinol treatment in rhesus monkeys. J Pharmacol Exp Ther 342:843-849.
    • (2012) J Pharmacol Exp Ther , vol.342 , pp. 843-849
    • Hruba, L.1    Ginsburg, B.2    McMahon, L.R.3
  • 18
    • 84899953226 scopus 로고    scopus 로고
    • δ 9-THC exposure attenuates aversive effects and reveals appetitive effects of K2/'Spice' constituent JWH-018 in mice
    • Hyatt WS, Fantegrossi WE (2014). δ9-THC exposure attenuates aversive effects and reveals appetitive effects of K2/'Spice' constituent JWH-018 in mice. Behav Pharmacol 25:253-257.
    • (2014) Behav Pharmacol , vol.25 , pp. 253-257
    • Hyatt, W.S.1    Fantegrossi, W.E.2
  • 19
    • 80051920710 scopus 로고    scopus 로고
    • Cannabinergic aminoalkylindoles, including AM678=JWH018 found in 'Spice', examined using drug (δ (9)-tetrahydrocannabinol) discrimination for rats
    • Järbe TU, Deng H, Vadivel SK, Makriyannis A (2011). Cannabinergic aminoalkylindoles, including AM678=JWH018 found in 'Spice', examined using drug (δ (9)-tetrahydrocannabinol) discrimination for rats. Behav Pharmacol 22:498-507.
    • (2011) Behav Pharmacol , vol.22 , pp. 498-507
    • Järbe, T.U.1    Deng, H.2    Vadivel, S.K.3    Makriyannis, A.4
  • 20
    • 84885575637 scopus 로고    scopus 로고
    • Biphasic effects of δ9-tetrahydrocannabinol on brain stimulation reward and motor activity
    • Katsidoni V, Kastellakis A, Panagis G (2013). Biphasic effects of δ9-tetrahydrocannabinol on brain stimulation reward and motor activity. Int J Neuropsychopharmacol 16:2273-2284.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 2273-2284
    • Katsidoni, V.1    Kastellakis, A.2    Panagis, G.3
  • 22
    • 84865860959 scopus 로고    scopus 로고
    • Identification of synthetic cannabinoids in herbal incense blends in the United States
    • Logan BK, Reinhold LE, Xu A, Diamond FX (2012). Identification of synthetic cannabinoids in herbal incense blends in the United States. J Forensic Sci 57:1168-1180.
    • (2012) J Forensic Sci , vol.57 , pp. 1168-1180
    • Logan, B.K.1    Reinhold, L.E.2    Xu, A.3    Diamond, F.X.4
  • 23
    • 84901833260 scopus 로고    scopus 로고
    • In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid δ9-THC in mice: Inhalation versus intraperitoneal injection
    • Marshell R, Kearney-Ramos T, Brents LK, Hyatt WS, Tai S, Prather PL, Fantegrossi WE (2014). In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid δ9-THC in mice: Inhalation versus intraperitoneal injection. Pharmacol Biochem Behav 124:40-47.
    • (2014) Pharmacol Biochem Behav , vol.124 , pp. 40-47
    • Marshell, R.1    Kearney-Ramos, T.2    Brents, L.K.3    Hyatt, W.S.4    Tai, S.5    Prather, P.L.6    Fantegrossi, W.E.7
  • 25
    • 0344683235 scopus 로고    scopus 로고
    • National Research Council. 8th ed. Washington, DC: The National Academies Press
    • National Research Council (2011). Guide for the care and use of laboratory animals. 8th ed. Washington, DC: The National Academies Press.
    • (2011) Guide for the Care and Use of Laboratory Animals
  • 26
    • 84857767642 scopus 로고    scopus 로고
    • Scheduling update
    • Office of Forensic Sciences
    • Office of Forensic Sciences (2010). Scheduling update. Microgram Bulletin 44:1-16.
    • (2010) Microgram Bulletin , vol.44 , pp. 1-16
  • 27
    • 84876424034 scopus 로고    scopus 로고
    • Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors
    • Rajasekaran M, Brents LK, Franks LN, Moran JH, Prather PL (2013). Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors. Toxicol Appl Pharmacol 269:100-108.
    • (2013) Toxicol Appl Pharmacol , vol.269 , pp. 100-108
    • Rajasekaran, M.1    Brents, L.K.2    Franks, L.N.3    Moran, J.H.4    Prather, P.L.5
  • 28
    • 84906053619 scopus 로고    scopus 로고
    • JWH-018 in rhesus monkeys: Differential antagonism of discriminative stimulus, rate-decreasing, and hypothermic effects
    • Rodriguez JS, McMahon LR (2014). JWH-018 in rhesus monkeys: differential antagonism of discriminative stimulus, rate-decreasing, and hypothermic effects. Eur J Pharmacol 740:151-159.
    • (2014) Eur J Pharmacol , vol.740 , pp. 151-159
    • Rodriguez, J.S.1    McMahon, L.R.2
  • 29
    • 0030425575 scopus 로고    scopus 로고
    • Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
    • Showalter VM, Compton DR, Martin BR, Abood ME (1996). Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. J Pharmacol Exp Ther 278:989-999.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 989-999
    • Showalter, V.M.1    Compton, D.R.2    Martin, B.R.3    Abood, M.E.4
  • 30
    • 84871330231 scopus 로고    scopus 로고
    • Internet highs - Seizures after consumption of synthetic cannabinoids purchased online
    • Tofighi B, Lee JD (2012). Internet highs - seizures after consumption of synthetic cannabinoids purchased online. J Addict Med 6:240-241.
    • (2012) J Addict Med , vol.6 , pp. 240-241
    • Tofighi, B.1    Lee, J.D.2
  • 32
    • 84902689585 scopus 로고    scopus 로고
    • Cross-substitution of δ9-tetrahydrocannabinol and JWH-018 in drug discrimination in rats
    • Wiley JL, Lefever TW, Cortes RA, Marusich JA (2014). Cross-substitution of δ9-tetrahydrocannabinol and JWH-018 in drug discrimination in rats. Pharmacol Biochem Behav 124C:123-128.
    • (2014) Pharmacol Biochem Behav , vol.124 C , pp. 123-128
    • Wiley, J.L.1    Lefever, T.W.2    Cortes, R.A.3    Marusich, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.