메뉴 건너뛰기




Volumn 124, Issue , 2014, Pages 40-47

In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid Δ9-THC in mice: Inhalation versus intraperitoneal injection

Author keywords

Antinociception; Behavior; Cannabinoids; Drug discrimination; Hypothermia; Locomotor activity

Indexed keywords

3 (1 NAPHTHOYL) 1 PENTYLINDOLE; CANNABINOID 1 RECEPTOR; CANNABINOID DERIVATIVE; DRONABINOL; JWH 073; RIMONABANT; SODIUM CHLORIDE; UNCLASSIFIED DRUG; 1-PENTYL-3-(1-NAPHTHOYL)INDOLE; INDOLE DERIVATIVE; JWH-073; NAPHTHALENE DERIVATIVE;

EID: 84901833260     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2014.05.010     Document Type: Article
Times cited : (79)

References (26)
  • 1
    • 77952664328 scopus 로고    scopus 로고
    • JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist
    • B.K. Atwood, J. Huffman, A. Straiker, and K. Mackie JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist Br J Pharmacol 160 2010 585 593
    • (2010) Br J Pharmacol , vol.160 , pp. 585-593
    • Atwood, B.K.1    Huffman, J.2    Straiker, A.3    Mackie, K.4
  • 2
    • 79960003774 scopus 로고    scopus 로고
    • Phase i hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity
    • L.K. Brents, E.E. Reichard, S.M. Zimmerman, J.H. Moran, W.E. Fantegrossi, and P.L. Prather Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity PLoS One 6 7 2011 e21917
    • (2011) PLoS One , vol.6 , Issue.7 , pp. 21917
    • Brents, L.K.1    Reichard, E.E.2    Zimmerman, S.M.3    Moran, J.H.4    Fantegrossi, W.E.5    Prather, P.L.6
  • 3
    • 84857372061 scopus 로고    scopus 로고
    • Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity
    • L.K. Brents, A. Gallus-Zawada, A. Radominska-Pandya, T. Vasiljevik, T.E. Prisinzano, and W.E. Fantegrossi et al. Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity Biochem Pharmacol 83 7 2012 952 961
    • (2012) Biochem Pharmacol , vol.83 , Issue.7 , pp. 952-961
    • Brents, L.K.1    Gallus-Zawada, A.2    Radominska-Pandya, A.3    Vasiljevik, T.4    Prisinzano, T.E.5    Fantegrossi, W.E.6
  • 4
    • 84882433884 scopus 로고    scopus 로고
    • Differential drug-drug interactions of the synthetic cannabinoids JWH-018 and JWH-073: Implications for drug abuse liability and pain therapy
    • L.K. Brents, S.M. Zimmerman, A.R. Saffell, P.L. Prather, and W.E. Fantegrossi Differential drug-drug interactions of the synthetic cannabinoids JWH-018 and JWH-073: implications for drug abuse liability and pain therapy J Pharmacol Exp Ther 346 3 2013 350 361
    • (2013) J Pharmacol Exp Ther , vol.346 , Issue.3 , pp. 350-361
    • Brents, L.K.1    Zimmerman, S.M.2    Saffell, A.R.3    Prather, P.L.4    Fantegrossi, W.E.5
  • 6
    • 0025543782 scopus 로고
    • Conformationally restrained aminoalkylindoles: Potent, stereoselective ligands at the cannabinoid binding site
    • K.G. Estep, T.E. D'Ambra, E.M. Olefirowicz, M.R. Bell, M.A. Eissenstat, and D.A. Haycock et al. Conformationally restrained aminoalkylindoles: potent, stereoselective ligands at the cannabinoid binding site NIDA Res Monogr 105 1990 300 301
    • (1990) NIDA Res Monogr , vol.105 , pp. 300-301
    • Estep, K.G.1    D'Ambra, T.E.2    Olefirowicz, E.M.3    Bell, M.R.4    Eissenstat, M.A.5    Haycock, D.A.6
  • 7
    • 66749120158 scopus 로고    scopus 로고
    • Discriminative stimulus effects of 3,4-methylenedioxymethamphetamine and its enantiomers in mice: Pharmacokinetic considerations
    • W.E. Fantegrossi, N. Murai, B.O. Mathúna, N. Pizarro, and R. de la Torre Discriminative stimulus effects of 3,4-methylenedioxymethamphetamine and its enantiomers in mice: pharmacokinetic considerations J Pharmacol Exp Ther 329 3 2009 1006 1015
    • (2009) J Pharmacol Exp Ther , vol.329 , Issue.3 , pp. 1006-1015
    • Fantegrossi, W.E.1    Murai, N.2    Mathúna, B.O.3    Pizarro, N.4    De La Torre, R.5
  • 8
    • 84855507862 scopus 로고    scopus 로고
    • Beyond THC: The new generation of cannabinoid designer drugs
    • L. Fattore, and W. Fratta Beyond THC: the new generation of cannabinoid designer drugs Front Behav Neurosci 5 2011 1 12
    • (2011) Front Behav Neurosci , vol.5 , pp. 1-12
    • Fattore, L.1    Fratta, W.2
  • 9
    • 0034941981 scopus 로고    scopus 로고
    • Intravenous self-administration of the cannabinoid CB1 receptor agonist WIN 55,212-2 in rats
    • DOI 10.1007/s002130100734
    • L. Fattore, G. Cossu, C.M. Martellotta, and W. Fratta Intravenous self-administration of the cannabinoid CB1 receptor agonist WIN 55,212-2 in rats Psychopharmacology (Berlin) 156 2001 410 416 (Pubitemid 32695850)
    • (2001) Psychopharmacology , vol.156 , Issue.4 , pp. 410-416
    • Fattore, L.1    Cossu, G.2    Martellotta, C.M.3    Fratta, W.4
  • 10
    • 33947489961 scopus 로고
    • Isolation, structure and partial synthesis of an active constituent of hashish
    • Y. Gaoni, and R. Mechoulam Isolation, structure and partial synthesis of an active constituent of hashish J Am Chem Soc 86 1964 1646 1647
    • (1964) J Am Chem Soc , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 11
    • 0242289524 scopus 로고    scopus 로고
    • Neuroadaptive effects of active versus passive drug administration in addiction research
    • DOI 10.1016/j.tips.2003.09.006
    • E.H. Jacobs, A.B. Smit, T.J. de Vries, and A.N. Schoffelmeer Neuroadaptive effects of active versus passive drug administration in addiction research Trends Pharmacol Sci 24 11 2003 566 573 (Pubitemid 37357140)
    • (2003) Trends in Pharmacological Sciences , vol.24 , Issue.11 , pp. 566-573
    • Jacobs, E.H.1    Smit, A.B.2    De Vries, T.J.3    Schoffelmeer, A.N.M.4
  • 13
    • 20444419001 scopus 로고    scopus 로고
    • Self-administration of cannabinoids by experimental animals and human marijuana smokers
    • DOI 10.1016/j.pbb.2005.01.026, PII S0091305705001395
    • Z. Justinova, S.R. Goldberg, S.J. Heishman, and G. Tanda Self-administration of cannabinoids by experimental animals and human marijuana smokers Pharmacol Biochem Behav 81 2 2005 285 299 (Pubitemid 40807128)
    • (2005) Pharmacology Biochemistry and Behavior , vol.81 , Issue.2 SPEC. ISSUE. , pp. 285-299
    • Justinova, Z.1    Goldberg, S.R.2    Heishman, S.J.3    Tanda, G.4
  • 15
    • 84865860959 scopus 로고    scopus 로고
    • Identification of synthetic cannabinoids in herbal incense blends in the United States
    • B.K. Logan, L.E. Reinhold, A. Xu, and F.X. Diamond Identification of synthetic cannabinoids in herbal incense blends in the United States J Forensic Sci 57 5 2012 1168 1180
    • (2012) J Forensic Sci , vol.57 , Issue.5 , pp. 1168-1180
    • Logan, B.K.1    Reinhold, L.E.2    Xu, A.3    Diamond, F.X.4
  • 16
    • 0032495834 scopus 로고    scopus 로고
    • Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice
    • DOI 10.1016/S0306-4522(98)00052-9, PII S0306452298000529
    • M.C. Martellotta, G. Cossu, L. Fattore, G.L. Gessa, and W. Fratta Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice Neuroscience 85 1998 327 330 (Pubitemid 28218655)
    • (1998) Neuroscience , vol.85 , Issue.2 , pp. 327-330
    • Martellotta, M.C.1    Cossu, G.2    Fattore, L.3    Gessa, G.L.4    Fratta, W.5
  • 18
    • 70350452574 scopus 로고    scopus 로고
    • Discriminative stimulus effects of psychostimulants and hallucinogens in S(+)-3,4-methylenedioxymethamphetamine (MDMA) and R(-)-MDMA trained mice
    • K.S. Murnane, N. Murai, L.L. Howell, and W.E. Fantegrossi Discriminative stimulus effects of psychostimulants and hallucinogens in S(+)-3,4- methylenedioxymethamphetamine (MDMA) and R(-)-MDMA trained mice J Pharmacol Exp Ther 331 2 2009 717 723
    • (2009) J Pharmacol Exp Ther , vol.331 , Issue.2 , pp. 717-723
    • Murnane, K.S.1    Murai, N.2    Howell, L.L.3    Fantegrossi, W.E.4
  • 20
    • 0021368649 scopus 로고
    • First-pass elimination. Basic concepts and clinical consequences
    • S.M. Pond, and T.N. Tozer First-pass elimination. Basic concepts and clinical consequences Clin Pharmacokinet 9 1 1984 1 25 (Pubitemid 14180304)
    • (1984) Clinical Pharmacokinetics , vol.9 , Issue.1 , pp. 1-25
    • Pond, S.M.1    Tozer, T.N.2
  • 21
    • 84866989897 scopus 로고    scopus 로고
    • Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids
    • K.A. Seely, J. Lapoint, J.H. Moran, and L. Fattore Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids Prog Neuropsychopharmacol Biol Psychiatry 39 2 2012 234 243
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.39 , Issue.2 , pp. 234-243
    • Seely, K.A.1    Lapoint, J.2    Moran, J.H.3    Fattore, L.4
  • 22
    • 84887869784 scopus 로고    scopus 로고
    • Forensic investigation of K2, Spice, and "bath salt" commercial preparations: A three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds
    • K.A. Seely, A.L. Patton, C.L. Moran, M.L. Womack, P.L. Prather, and W.E. Fantegrossi et al. Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds Forensic Sci Int 233 1-3 2013 416 422
    • (2013) Forensic Sci Int , vol.233 , Issue.13 , pp. 416-422
    • Seely, K.A.1    Patton, A.L.2    Moran, C.L.3    Womack, M.L.4    Prather, P.L.5    Fantegrossi, W.E.6
  • 23
    • 70350348642 scopus 로고    scopus 로고
    • To scale or not to scale: The principles of dose extrapolation
    • V. Sharma, and J.H. McNeill To scale or not to scale: the principles of dose extrapolation Br J Pharmacol 157 6 2009 907 921
    • (2009) Br J Pharmacol , vol.157 , Issue.6 , pp. 907-921
    • Sharma, V.1    McNeill, J.H.2
  • 24
    • 84155164719 scopus 로고    scopus 로고
    • A survey study to characterize use of Spice products (synthetic cannabinoids)
    • R. Vandrey, K.E. Dunn, J.A. Fry, and E.R. Girling A survey study to characterize use of Spice products (synthetic cannabinoids) Drug Alcohol Depend 120 1-3 2012 238 241
    • (2012) Drug Alcohol Depend , vol.120 , Issue.13 , pp. 238-241
    • Vandrey, R.1    Dunn, K.E.2    Fry, J.A.3    Girling, E.R.4
  • 25
    • 77954954841 scopus 로고    scopus 로고
    • Spice drugs as a new trend: Mode of action, identification and legislation
    • I. Vardakou, C. Pistos, and Ch. Spiliopoulou Spice drugs as a new trend: mode of action, identification and legislation Toxicol Lett 197 3 2010 157 162
    • (2010) Toxicol Lett , vol.197 , Issue.3 , pp. 157-162
    • Vardakou, I.1    Pistos, C.2    Spiliopoulou, Ch.3
  • 26
    • 84869211772 scopus 로고    scopus 로고
    • Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice
    • J.M. Wiebelhaus, J.L. Poklis, A. Poklis, R.E. Vann, A.H. Lichtman, and L.E. Wise Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice Drug Alcohol Depend 126 3 2012 316 322
    • (2012) Drug Alcohol Depend , vol.126 , Issue.3 , pp. 316-322
    • Wiebelhaus, J.M.1    Poklis, J.L.2    Poklis, A.3    Vann, R.E.4    Lichtman, A.H.5    Wise, L.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.