Internet highs-seizures after consumption of synthetic cannabinoids purchased online

Journal of Addiction Medicine

Volumn 6, Issue 3, 2012, Pages 240-241

  Tofighi, Babak ^a   Lee, Joshua D ^a  

^a LENOX HILL HOSPITAL   (United States)

Author keywords

JWH 018; Spice drugs; Spirit; Synthetic cannabinoids

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CANNABINOID; CREATINE KINASE; ILLICIT DRUG; INFUSION FLUID; LORAZEPAM; TROPONIN;

ADULT; AGITATION; ARTICLE; ASSISTED VENTILATION; BITE; CASE REPORT; CONSCIOUSNESS DISORDER; DEPRESSION; DIAPHORESIS; DRUG ABUSE; DRUG MARKETING; DRUG USE; ELECTROCARDIOGRAPHY; HUMAN; HYPERTHERMIA; INCONTINENCE; INTENSIVE CARE; INTERNET; MALE; PRIORITY JOURNAL; RESPIRATORY ACIDOSIS; SEIZURE; SHOCK; SINUS TACHYCARDIA; SUPRAVENTRICULAR TACHYCARDIA; TACHYCARDIA; TONGUE BITING; TONIC CLONIC SEIZURE; TREATMENT RESPONSE;

ACIDOSIS, RESPIRATORY; CANNABINOIDS; ELECTROCARDIOGRAPHY; EPILEPSY, TONIC-CLONIC; GLASGOW COMA SCALE; HUMANS; INDOLES; INTENSIVE CARE; INTERNET; MALE; MARIJUANA ABUSE; MIDDLE AGED; NAPHTHALENES; SELF MEDICATION; STREET DRUGS; TACHYCARDIA, SUPRAVENTRICULAR; TETRAHYDROCANNABINOL;

EID: 84871330231     PISSN: 19320620     EISSN: 19353227     Source Type: Journal    
DOI: 10.1097/ADM.0b013e3182619004     Document Type: Article

References (18)

1. Aung MM, Griffin G, Huffman JW, et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding. Drug Alcohol Depend 2000;60(2):133-1340.
2. Auwarter V, Dresen S,Weinmann W, Muller M, Putz M, Ferreiros N. "Spice" and other herbal blends: harmless incense or cannabinoid designer drugs? J Mass Spectrom 2009;44(5):832-837.
3. Davies S,Wood DM, Smith G, et al. Purchasing "legal highs" on the Internet-is there consistency in what you get? QJM 2010;103(7):489-493.
4. Griffiths P, Sedefov R, Gallegos A, Lopez D. How globalization and market innovation challenge how we think about and respond to drug use: "Spice" a case study. Addiction 2010;105(6):951-953.
5. Gunderson EW, Haughey HM, Ait-Daoud N, Joshi AS, Hart CL. "Spice" and "K2" herbal highs: a case series and systematic review of the clinical effects and biopsychosocial implications of synthetic cannabinoid use in humans. Am J Addict 2012;21(4):320-326.
6. Huffman JW, Dai D, Martin BR, Compton DR. Design, synthesis and pharmacology of cannabimimetic indoles. Biol Med Chem Lett 1994;4: 563-566.
7. Huffman JW, Thompson AL,Wiley JL, Martin BR. Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorg Med Chem 2008;16(1):322-335.
8. Johnson LA, Johnson RL, Alfonzo C. Spice: a legal marijuana equivalent. Mil Med 2011;176(6):718-720.
9. Lapoint J, James LP, Moran CL, Nelson LS, Hoffman RS, Moran JH. Severe toxicity following synthetic cannabinoid ingestion. Clin Toxicol (Phila) 2011;49(8):760-764.
10. Marsicano G, Goodenough S, Monory K, et al. CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 2003;302(5642): 84-88.
11. Muller H, Sperling W, Kohrmann M, Huttner HB, Kornhuber J, Maler JM. The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes. Schizophr Res 2010;118(1-3):309-310.
12. Patrick J. Mother says "spice" nearly killed son. Herald J 2010. Available at: http://news.hjnews.com/news/local-news/article-57d2054e- 3a1c-11df-a46f-001cc4c03286.html. Accessed March 7, 2011. Archived by Website at: http://www.webcitation.org/5x0xPgipu.
13. Schneir AB, Baumbacher T. Convulsions associated with the use of a synthetic cannabinoid product. J Med Toxicol 2012;8(1):62-64.
14. Schneir AB, Cullen J, Ly BT. "Spice" girls: synthetic cannabinoid intoxication. J Emerg Med 2011;40(3):296-299.
15. Simmons J, Cookman L, Kang C, Skinner C. Three cases of "spice" exposure. Clin Toxicol (Phila) 2011a;49(5):431-433.
16. Simmons JR, Skinner CG, Williams J, Kang CS, Schwartz MD, Wills BK. Intoxication from smoking "Spice." Ann Emerg Med 2011b;57(2):187-188.
17. Swartz KE.Georgia senatorwants to make synthetic pot illegal. Atlanta J Constitut 2010. Available at: http://www.ajc.com/news/north-fulton/ georgiasenator-wants-to-346920.html. Accessed March 7, 2011. Archived byWebcite at: http://www.webcitation.org/5x0zpAL1Z).
18. Zimmermann US, Winkelmann PR, Pilhatsch M, Nees JA, Spanagel R, Schulz K. Withdrawal phenomena and dependence syndrome after the consumption of "spice gold." Dtsch Arztebl Int 2009;106(27): 464-467.