-
2
-
-
0026516004
-
Delta 9-tetrahydrocannabinol discrimination in rats as a model for cannabis intoxication
-
R.L. Balster, and W.R. Prescott Delta 9-tetrahydrocannabinol discrimination in rats as a model for cannabis intoxication Neurosci. Biobehav. Rev. 16 1992 55 62
-
(1992)
Neurosci. Biobehav. Rev.
, vol.16
, pp. 55-62
-
-
Balster, R.L.1
Prescott, W.R.2
-
3
-
-
79960003774
-
Phase i hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity
-
L.K. Brents, E.E. Reichard, S.M. Zimmerman, J.H. Moran, W.E. Fantegrossi, and P.L. Prather Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity PLoS One 6 2011 e21917
-
(2011)
PLoS One
, vol.6
, pp. 21917
-
-
Brents, L.K.1
Reichard, E.E.2
Zimmerman, S.M.3
Moran, J.H.4
Fantegrossi, W.E.5
Prather, P.L.6
-
4
-
-
33645088405
-
Activation of G-proteins in brain by endogenous and exogenous cannabinoids
-
S.R. Childers Activation of G-proteins in brain by endogenous and exogenous cannabinoids AAPS J. 8 2006 E112 E117
-
(2006)
AAPS J.
, vol.8
, pp. 112-E117
-
-
Childers, S.R.1
-
5
-
-
67651008656
-
CB1 receptor-independent actions of SR141716 on G-protein signaling: Coapplication with the mu-opioid agonist Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol unmasks novel, pertussis toxin-insensitive opioid signaling in mu-opioid receptor-Chinese hamster ovary cells
-
R. Cinar, and M. Szücs CB1 receptor-independent actions of SR141716 on G-protein signaling: coapplication with the mu-opioid agonist Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol unmasks novel, pertussis toxin-insensitive opioid signaling in mu-opioid receptor-Chinese hamster ovary cells J. Pharmacol. Exp. Ther. 330 2009 567 574
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.330
, pp. 567-574
-
-
Cinar, R.1
Szücs, M.2
-
6
-
-
0030423694
-
9-tetrahydrocannabinol-induced responses and apparent agonist activity
-
D.R. Compton, M.D. Aceto, J. Lowe, and B.R. Martin in vivo characterization of a specific cannabinoid receptor antagonist (SR141716A): inhibition of delta 9-tetrahydrocannabinol-induced responses and apparent agonist activity J. Pharmacol. Exp. Ther. 277 1996 586 594 (Pubitemid 27168965)
-
(1996)
Journal of Pharmacology and Experimental Therapeutics
, vol.277
, Issue.2
, pp. 586-594
-
-
Compton, D.R.1
Aceto, M.D.2
Lowe, J.3
Martin, B.R.4
-
7
-
-
8844248621
-
2receptor partial agonist BAY 59-3074 in the rat
-
J. De Vry, and K.R. Jentzsch Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat Eur. J. Pharmacol. 505 2004 127 133 (Pubitemid 39535684)
-
(2004)
European Journal of Pharmacology
, vol.505
, Issue.1-3
, pp. 127-133
-
-
De Vry, J.1
Jentzsch, K.R.2
-
8
-
-
0033026115
-
Large receptor reserve for cannabinoid actions in the central nervous system
-
A.N. Gifford, M. Bruneus, S.J. Gatley, R. Lan, A. Makriyannis, and N.D. Volkow Large receptor reserve for cannabinoid actions in the central nervous system J. Pharmacol. Exp. Ther. 288 1999 478 483 (Pubitemid 29119654)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.288
, Issue.2
, pp. 478-483
-
-
Gifford, A.N.1
Bruneus, M.2
Gatley, S.J.3
Lan, R.4
Makriyannis, A.5
Volkow, N.D.6
-
9
-
-
84055219353
-
JWH-018 and JWH-073: Δ9-tetrahydrocannabinol-like discriminative stimulus effects in monkeys
-
B.C. Ginsburg, D.R. Schulze, L. Hruba, and L.R. McMahon JWH-018 and JWH-073: Δ9-tetrahydrocannabinol-like discriminative stimulus effects in monkeys J. Pharmacol. Exp. Ther. 340 2012 37 45
-
(2012)
J. Pharmacol. Exp. Ther.
, vol.340
, pp. 37-45
-
-
Ginsburg, B.C.1
Schulze, D.R.2
Hruba, L.3
McMahon, L.R.4
-
10
-
-
9644281057
-
2receptor agonists
-
J.W. Huffman, G. Zengin, M.J. Wu, J. Lu, G. Hynd, K. Bushell, A.L. Thompson, S. Bushell, C. Tartal, D.P. Hurst, P.H. Reggio, D.E. Selley, M.P. Cassidy, J.L. Wiley, and B. Martin Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists Bioorg. Med. Chem. 13 2005 89 112 (Pubitemid 39575695)
-
(2005)
Bioorganic and Medicinal Chemistry
, vol.13
, Issue.1
, pp. 89-112
-
-
Huffman, J.W.1
Zengin, G.2
Wu, M.-J.3
Lu, J.4
Hynd, G.5
Bushell, K.6
Thompson, A.L.S.7
Bushell, S.8
Tartal, C.9
Hurst, D.P.10
Reggio, P.H.11
Selley, D.E.12
Cassidy, M.P.13
Wiley, J.L.14
Martin, B.R.15
-
11
-
-
84865159568
-
Apparent inverse relationship between cannabinoid agonist efficacy and tolerance/cross-tolerance produced by Δ9-tetrahydrocannabinol treatment in rhesus monkeys
-
L. Hruba, B.C. Ginsburg, and L.R. McMahon Apparent inverse relationship between cannabinoid agonist efficacy and tolerance/cross-tolerance produced by Δ9-tetrahydrocannabinol treatment in rhesus monkeys J. Pharmacol. Exp. Ther. 342 2012 843 849
-
(2012)
J. Pharmacol. Exp. Ther.
, vol.342
, pp. 843-849
-
-
Hruba, L.1
Ginsburg, B.C.2
McMahon, L.R.3
-
12
-
-
0344683235
-
-
Of Laboratory Animal Resources I. 8th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council Washington, DC
-
Institute of Laboratory Animal Resources Guide for the Care and Use of Laboratory Animals 8th ed. 2011 Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council Washington, DC
-
(2011)
Guide for the Care and Use of Laboratory Animals
-
-
-
13
-
-
72649092512
-
Discriminative stimulus functions of methanandamide and delta(9)-THC in rats: Tests with aminoalkylindoles (WIN55,212-2 and AM678) and ethanol
-
T.U.C. Järbe, C. Li, S.K. Vadivel, and A. Makriyannis Discriminative stimulus functions of methanandamide and delta(9)-THC in rats: tests with aminoalkylindoles (WIN55,212-2 and AM678) and ethanol Psychopharmacology 208 2010 87 98
-
(2010)
Psychopharmacology
, vol.208
, pp. 87-98
-
-
Järbe, T.U.C.1
Li, C.2
Vadivel, S.K.3
Makriyannis, A.4
-
14
-
-
84874441447
-
Cannabinoid discrimination and antagonism by CB(1) neutral and inverse agonist antagonists
-
B.D. Kangas, M.S. Delatte, V.K. Vemuri, G.A. Thakur, S.P. Nikas, K.V. Subramanian, V.G. Shukla, A. Makriyannis, and J. Bergman Cannabinoid discrimination and antagonism by CB(1) neutral and inverse agonist antagonists J. Pharmacol. Exp. Ther. 344 2013 561 567
-
(2013)
J. Pharmacol. Exp. Ther.
, vol.344
, pp. 561-567
-
-
Kangas, B.D.1
Delatte, M.S.2
Vemuri, V.K.3
Thakur, G.A.4
Nikas, S.P.5
Subramanian, K.V.6
Shukla, V.G.7
Makriyannis, A.8
Bergman, J.9
-
16
-
-
0025787612
-
Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs
-
B.R. Martin, D.R. Compton, B.F. Thomas, W.R. Prescott, P.J. Little, R.K. Razdan, M.R. Johnson, L.S. Melvin, R. Mechoulam, and S.J. Ward Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs Pharmacol. Biochem. Behav. 40 1991 471 478
-
(1991)
Pharmacol. Biochem. Behav.
, vol.40
, pp. 471-478
-
-
Martin, B.R.1
Compton, D.R.2
Thomas, B.F.3
Prescott, W.R.4
Little, P.J.5
Razdan, R.K.6
Johnson, M.R.7
Melvin, L.S.8
Mechoulam, R.9
Ward, S.J.10
-
17
-
-
33751182888
-
Characterization of cannabinoid agonists and apparent pA2 analysis of cannabinoid antagonists in rhesus monkeys discriminating Delta9-tetrahydrocannabinol
-
L.R. McMahon Characterization of cannabinoid agonists and apparent pA2 analysis of cannabinoid antagonists in rhesus monkeys discriminating Delta9-tetrahydrocannabinol J. Pharmacol. Exp. Ther. 319 2006 1211 1218
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.319
, pp. 1211-1218
-
-
McMahon, L.R.1
-
18
-
-
62449087101
-
Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol
-
L.R. McMahon Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol Psychopharmacology 203 2009 219 228
-
(2009)
Psychopharmacology
, vol.203
, pp. 219-228
-
-
McMahon, L.R.1
-
19
-
-
79551486841
-
9-tetrahydrocannabinol treatment in rhesus monkeys: Differential tolerance and cross-tolerance among cannabinoids
-
9-tetrahydrocannabinol treatment in rhesus monkeys: differential tolerance and cross-tolerance among cannabinoids Br. J. Pharmacol. 162 2011 1060 1073
-
(2011)
Br. J. Pharmacol.
, vol.162
, pp. 1060-1073
-
-
McMahon, L.R.1
-
20
-
-
26044474696
-
9-THC in rhesus monkeys
-
Behavioural Pharmacology of Cannabinoids
-
L.R. McMahon, M.R. Amin, and C.P. France SR 141716A differentially attenuates the behavioral effects of delta9-THC in rhesus monkeys Behav. Pharmacol. 16 2005 363 372 (Pubitemid 41404807)
-
(2005)
Behavioural Pharmacology
, vol.16
, Issue.5-6
, pp. 363-372
-
-
McMahon, L.R.1
Amin, M.R.2
France, C.P.3
-
21
-
-
44449118561
-
9-tetrahydrocannabinol in C57BL/6J mice
-
L.R. McMahon, B.C. Ginsburg, and R.J. Lamb Cannabinoid agonists differentially substitute for the discriminative stimulus effects of Delta(9)-tetrahydrocannabinol in C57BL/6J mice Psychopharmacology 198 2008 487 495 (Pubitemid 351754667)
-
(2008)
Psychopharmacology
, vol.198
, Issue.4
, pp. 487-495
-
-
McMahon, L.R.1
Ginsburg, B.C.2
Lamb, R.J.3
-
22
-
-
77951979345
-
The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes
-
H. Müller, W. Sperling, M. Köhrmann, H.B. Huttner, J. Kornhuber, and J.M. Maler The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes Schizophr. Res. 118 2010 309 310
-
(2010)
Schizophr. Res.
, vol.118
, pp. 309-310
-
-
Müller, H.1
Sperling, W.2
Köhrmann, M.3
Huttner, H.B.4
Kornhuber, J.5
Maler, J.M.6
-
24
-
-
77950653576
-
Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists
-
R.G. Pertwee Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists Curr. Med. Chem. 17 2010 1360 1381
-
(2010)
Curr. Med. Chem.
, vol.17
, pp. 1360-1381
-
-
Pertwee, R.G.1
-
25
-
-
0028129936
-
SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
-
M. Rinaldi-Carmona, F. Barth, M. Héaulme, D. Shire, B. Calandra, C. Congy, S. Martinez, J. Maruani, G. Néliat, D. Caput, P. Ferrara, P. Soubrié, J.C. Brelière, and G. Le Fur SR141716A, a potent and selective antagonist of the brain cannabinoid receptor FEBS Lett. 350 1994 240 244 (Pubitemid 24268029)
-
(1994)
FEBS Letters
, vol.350
, Issue.2-3
, pp. 240-244
-
-
Rinaldi-Carmona, M.1
-
26
-
-
84857796142
-
Convulsions associated with the use of a synthetic cannabinoid product
-
A.B. Schneir, and T. Baumbacher Convulsions associated with the use of a synthetic cannabinoid product J. Med. Toxicol. 8 2012 62 64
-
(2012)
J. Med. Toxicol.
, vol.8
, pp. 62-64
-
-
Schneir, A.B.1
Baumbacher, T.2
-
27
-
-
84887869784
-
Forensic investigation of K2, Spice, and "bath salt" commercial preparations: A three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds
-
K.A. Seely, A.L. Patton, C.L. Moran, M.L. Womack, P.L. Prather, W.E. Fantegrossi, A. Radominska-Pandya, G.W. Endres, K.B. Channell, N.H. Smith, K.R. McCain, L.P. James, and J.H. Moran Forensic investigation of K2, Spice, and "bath salt" commercial preparations: A three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds Forensic. Sci. Int. 233 2013 416 422
-
(2013)
Forensic. Sci. Int.
, vol.233
, pp. 416-422
-
-
Seely, K.A.1
Patton, A.L.2
Moran, C.L.3
Womack, M.L.4
Prather, P.L.5
Fantegrossi, W.E.6
Radominska-Pandya, A.7
Endres, G.W.8
Channell, K.B.9
Smith, N.H.10
McCain, K.R.11
James, L.P.12
Moran, J.H.13
-
28
-
-
78751564069
-
Intoxication from smoking "spice
-
J.R. Simmons, C.G. Skinner, J. Williams, C.S. Kang, M.D. Schwartz, and B.K. Wills Intoxication from smoking "spice Ann. Emerg. Med. 57 2011 187 188
-
(2011)
Ann. Emerg. Med.
, vol.57
, pp. 187-188
-
-
Simmons, J.R.1
Skinner, C.G.2
Williams, J.3
Kang, C.S.4
Schwartz, M.D.5
Wills, B.K.6
-
30
-
-
0026715833
-
Receptor regulation, competitive antagonism and pA2
-
R.J. Tallarida, and R.B. Raffa Receptor regulation, competitive antagonism and pA2 Life Sci. 51 1992 PL61 PL65
-
(1992)
Life Sci.
, vol.51
, pp. 61-PL65
-
-
Tallarida, R.J.1
Raffa, R.B.2
-
31
-
-
77953344825
-
A teenager with agitation: Higher than she should have climbed
-
D. Vearrier, and K.C. Osterhoudt A teenager with agitation: higher than she should have climbed Pediatr. Emerg. Care 26 2010 462 465
-
(2010)
Pediatr. Emerg. Care
, vol.26
, pp. 462-465
-
-
Vearrier, D.1
Osterhoudt, K.C.2
-
32
-
-
0031864382
-
Structure-activity relationships of indole- and pyrrole-derived cannabinoids
-
J.L. Wiley, D.R. Compton, D. Dai, J.A. Lainton, M. Phillips, J.W. Huffman, and B.R. Martin Structure-activity relationships of indole- and pyrrole-derived cannabinoids J. Pharmacol. Exp. Ther. 285 1998 995 1004 (Pubitemid 28277896)
-
(1998)
Journal of Pharmacology and Experimental Therapeutics
, vol.285
, Issue.3
, pp. 995-1004
-
-
Wiley, J.L.1
Compton, D.R.2
Dai, D.3
Lainton, J.A.H.4
Phillips, M.5
Huffman, J.W.6
Martin, B.R.7
-
33
-
-
80051950901
-
Dissimilar cannabinoid substitution patterns in mice trained to discriminate Δ(9)-tetrahydrocannabinol or methanandamide from vehicle
-
J.L. Wiley, D. Matthew Walentiny, R.E. Vann, and C.Y. Baskfield Dissimilar cannabinoid substitution patterns in mice trained to discriminate Δ(9)-tetrahydrocannabinol or methanandamide from vehicle Behav. Pharmacol. 22 2011 480 488
-
(2011)
Behav. Pharmacol.
, vol.22
, pp. 480-488
-
-
Wiley, J.L.1
Matthew Walentiny, D.2
Vann, R.E.3
Baskfield, C.Y.4
-
35
-
-
0026769789
-
Discriminative stimulus effects of morphine: Effects of training dose on agonist and antagonist effects of mu opioids
-
A.M. Young, M.A. Masaki, and C. Geula Discriminative stimulus effects of morphine: effects of training dose on agonist and antagonist effects of mu opioids J. Pharmacol. Exp. Ther. 261 1992 246 257
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.261
, pp. 246-257
-
-
Young, A.M.1
Masaki, M.A.2
Geula, C.3
|