TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia

Cell Death and Disease

Volumn 5, Issue 11, 2014, Pages

  Ye, M ^a   Yang, W ^a,b   Ainscough, J F ^b   Hu, X P ^a   Li, X ^b   Sedo, A ^b   Zhang, X H ^a   Zhang, X ^a   Chen, Z ^a   Li, X M ^a   Beech, D J ^b   Sivaprasadarao, A ^b   Luo, J H ^a   Jiang, L H ^b,c  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; ZINC ION; HYDROGEN PEROXIDE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM2 PROTEIN, MOUSE; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; HIPPOCAMPAL CA1 REGION; IN VITRO STUDY; IN VIVO STUDY; MEMORY DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; REPERFUSION; REVIEW; TIME LAPSE IMAGING; ANIMAL; C57BL MOUSE; COMPLICATION; CYTOSOL; DEFICIENCY; KNOCKOUT MOUSE; MALE; MEMORY DISORDERS; METABOLISM; PATHOLOGY; REPERFUSION INJURY; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; CA1 REGION, HIPPOCAMPAL; CELL DEATH; CYTOSOL; HYDROGEN PEROXIDE; ISCHEMIC ATTACK, TRANSIENT; MALE; MEMORY DISORDERS; MICE, INBRED C57BL; MICE, KNOCKOUT; REPERFUSION INJURY; TRPM CATION CHANNELS; ZINC;

EID: 84927920574     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.494     Document Type: Review

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