TRPM2 channel activation following in vitro ischemia contributes to male hippocampal cell death

Neuroscience Letters

Volumn 530, Issue 1, 2012, Pages 41-46

  Verma, S ^a   Quillinan, N ^a,b   Yang, Y F ^a   Nakayama, S ^a   Cheng, J ^a   Kelley, M H ^a   Herson, P S ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Excitotoxicity; Hippocampus; Ischemia; Neuroprotection; TRPM2

Indexed keywords

CLUSTERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DEPOLARIZATION; ELECTROPHYSIOLOGY; EMBRYO; FEMALE; HIPPOCAMPUS; IN VITRO STUDY; ISCHEMIA; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACTION POTENTIALS; ANIMALS; CELL DEATH; FEMALE; GENE KNOCKDOWN TECHNIQUES; GLUCOSE; HIPPOCAMPUS; ISCHEMIA; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; OXYGEN; PATCH-CLAMP TECHNIQUES; PREGNANCY; PRIMARY CELL CULTURE; SEX CHARACTERISTICS; TRPM CATION CHANNELS;

EID: 84868301057     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.09.044     Document Type: Article

References (24)

1. Aarts M., Lihara K., Wei W.L., Xiong Z.G., Arundine M., Cerwinski W., MacDonald J.F., Tymianski M. A key role for TRPM7 channels in anoxic neuronal death. Cell 2003, 115:863-877.
2. Besancon E., Guo S., Lok J., Tymianski M., Lo E.H. Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke. Trends in Pharmacological Sciences 2008, 29:268-275.
3. Eisfeld J., Luckhoff A. TRPM2. Handbook of Experimental Pharmacology 2007, 237-252.
4. Forder J.P., Tymianski M. Postsynaptic mechanisms of excitotoxicity: involvement of postsynaptic density proteins, radicals, and oxidant molecules. Neuroscience 2009, 158:293-300.
5. Ginsberg M.D. Neuroprotection for ischemic stroke: past, present and future. Neuropharmacology 2008, 55:363-389.
6. 2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Molecular Cell 2002, 9:163-173.
7. 2 in the rat insulin-secreting cell line CRI-G1. Journal of Physiology 1997, 501(Pt 1):59-66.
8. Herson P.S., Dulock K.A., Ashford M.L. Characterization of a nicotinamide-adenine dinucleotide-dependent cation channel in the CRI-G1 rat insulinoma cell line. Journal of Physiology 1997, 505(Pt 1):65-76.
9. Herson P.S., Lee K., Pinnock R.D., Hughes J., Ashford M.L. Hydrogen peroxide induces intracellular calcium overload by activation of a non-selective cation channel in an insulin-secreting cell line. Journal of Biological Chemistry 1999, 274:833-841.
10. Horn M., Schlote W. Delayed neuronal death and delayed neuronal recovery in the human brain following global ischemia. Acta Neuropathologica (Berlin) 1992, 85:79-87.
11. Jia J., Verma S., Nakayama S., Quillinan N., Grafe M.R., Hurn P.D., Herson P.S. Sex differences in neuroprotection provided by inhibition of TRPM2 channels following experimental stroke. Journal of Cerebral Blood Flow and Metabolism 2011, 31:2160-2168.
12. Lim C., Alexander M.P., LaFleche G., Schnyer D.M., Verfaellie M. The neurological and cognitive sequelae of cardiac arrest. Neurology 2004, 63:1774-1778.
13. MacDonald J.F., Jackson M.F. Transient receptor potential channels of the melastatin family and ischemic responses of central neurons. Stroke 2007, 38:665-669.
14. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods 1983, 65:55-63.
15. 2+ channel protein (TRPC7) highly expressed in brain. Genomics 1998, 54:124-131.
16. 2+-dependent induction of TRPM2 currents in hippocampal neurons. Journal of Physiology 2009, 587:965-979.
17. Pignataro G., Simon R.P., Xiong Z.G. Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia. Brain 2007, 130:151-158.
18. Roger V.L., Go A.S., Lloyd-Jones D.M., Benjamin E.J., Berry J.D., Borden W.B., Bravata D.M., Dai S., Ford E.S., Fox C.S., Fullerton H.J., Gillespie C., Hailpern S.M., Heit J.A., Howard V.J., Kissela B.M., Kittner S.J., Lackland D.T., Lichtman J.H., Lisabeth L.D., Makuc D.M., Marcus G.M., Marelli A., Matchar D.B., Moy C.S., Mozaffarian D., Mussolino M.E., Nichol G., Paynter N.P., Soliman E.Z., Sorlie P.D., Sotoodehnia N., Turan T.N., Virani S.S., Wong N.D., Woo D., Turner M.B. Heart Disease and Stroke Statistics - 2012 update: a report from the American Heart Association. Circulation 2012, 125:e2-e220.
19. Simard J.M., Tarasov K.V., Gerzanich V. Non-selective cation channels, transient receptor potential channels and ischemic stroke. Biochimica et Biophysica Acta 2007, 1772:947-957.
20. Smith M.A., Herson P.S., Lee K., Pinnock R.D., Ashford M.L. Hydrogen-peroxide-induced toxicity of rat striatal neurones involves activation of a non-selective cation channel. Journal of Physiology 2003, 547:417-425.
21. Sun H.S., Jackson M.F., Martin L.J., Jansen K., Teves L., Cui H., Kiyonaka S., Mori Y., Jones M., Forder J.P., Golde T.E., Orser B.A., MacDonald J.F., Tymianski M. Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. Nature Neuroscience 2009, 12:1300-1307.
22. Szydlowska K., Tymianski M. Calcium, ischemia and excitotoxicity. Cell Calcium 2010, 47:122-129.
23. Wu L.J., Sweet T.B., Clapham D.E. International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family. Pharmacological Reviews 2010, 62:381-404.
24. Xiong Z.G., Zhu X.M., Chu X.P., Minami M., Hey J., Wei W.L., MacDonald J.F., Wemmie J.A., Price M.P., Welsh M.J., Simon R.P. Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell 2004, 118:687-698.