46th Walter J. Zeiter Lecture, Exercise Is Rehabilitation Medicine: Our History and Future

PM and R

Volumn 7, Issue 4, 2015, Pages 345-353

  Becker, Bruce E ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTERY COMPLIANCE; ARTICLE; EUROPE; EXERCISE; HEALTH PROMOTION; HISTORY OF MEDICINE; HUMAN; INFLAMMATION; MUSCLE CHARACTERISTICS AND FUNCTIONS; MYOPLASTICITY; NERVE REGENERATION; NEUROPROTECTION; NONHUMAN; PHYSICAL MEDICINE; PLASTICITY; PRIORITY JOURNAL; REHABILITATION MEDICINE; WAR; WELLBEING; EDUCATION; HISTORY;

EXERCISE; HEALTH PROMOTION; HISTORY, 18TH CENTURY; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HISTORY, ANCIENT; HUMANS; PHYSICAL AND REHABILITATION MEDICINE;

EID: 84927761015     PISSN: 19341482     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pmrj.2015.02.013     Document Type: Article

References (78)

1. Tipton C.M. The history of "Exercise Is Medicine" in ancient civilizations. Adv Physiol Educ 2014, 38:109-117.
2. Strax T.E. Moral and ethical decisions: To be or not to be. The 39th Walter J. Zeiter Lecture. Arch Phys Med Rehabil 2008, 89:4-9.
3. Tipton C.M. Susruta of India, an unrecognized contributor to thehistory of exercise physiology. J Appl Physiol (1985) 2008, 104:1553-1556.
4. Garber C.E., Blissmer B., Deschenes M.R., et al. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: Guidance for prescribing exercise. Med Sci Sports Exerc 2011, 43:1334-1359.
5. American College of Sports Medicine, Chodzko-Zajko W.J., Proctor D.N., et al. American College of Sports Medicine position stand. Exercise and physical activity for older adults. Med Sci Sports Exerc 2009, 41:1510-1530.
6. Berryman J.W. Exercise is medicine: A historical perspective. Curr Sports Med Rep 2010, 9:195-201.
7. Coulter J. Physical Therapy 1932, Vol 7. P. B. Hoebner, New York, NY, 23, 27-29.
8. Starr P. The Social Transformation of American Medicine 1982, Basic Books, New York, NY, 118-121.
9. Verville R.E. War, Politics, and Philanthropy: The History of Rehabilitation Medicine 2009, University Press of America, Lanham, MD, 8-9, 12-13, 38.
10. Oshinsky D. Polio: An American Story 2005, Oxford University Press, Oxford, NY, 26, 35-40.
11. Verville R.E., Ditunno J.F. Franklin Delano Roosevelt, polio, and the Warm Springs experiment: Its impact on physical medicine and rehabilitation. PM R 2013, 5:3-8.
12. Harrison T.R. Abuse of rest as a therapeutic measure for patients with cardiovascular disease. JAMA 1944, 125:1075-1090.
13. Krusen F.H. The abuse of rest as a therapeutic agent. Postgrad Med 1947, 2:84-89.
14. Morris J.N., Heady J.A., Raffle P.A., Roberts C.G., Parks J.W. Coronary heart-disease and physical activity of work. Lancet 1953, 265:1111-1120. concl.
15. Haskell W.L., Blair S.N., Hill J.O. Physical activity: Health outcomes and importance for public health policy. Prev Med 2009, 49:280-282.
16. Maruthur N.M., Ma Y., Delahanty L.M., et al. Early response to preventive strategies in the Diabetes Prevention Program. J Gen Intern Med 2013, 28:1629-1636.
17. Hillman C.H., Erickson K.I., Kramer A.F. Be smart, exercise your heart:Exercise effects on brain and cognition. Nat Rev Neurosci 2008, 9:58-65.
18. Lojovich J.M. The relationship between aerobic exercise and cognition: Is movement medicinal?. J Head Trauma Rehabil 2010, 25:184-192.
19. Leal G., Comprido D., Duarte C.B. BDNF-induced local protein synthesis and synaptic plasticity. Neuropharmacology 2014, 76(PtC):639-656.
20. Whiteman A.S., Young D.E., He X., et al. Interaction between serum BDNF and aerobic fitness predicts recognition memory in healthy young adults. Behav Brain Res 2014, 259:302-312.
21. Xu B. BDNF (I)rising from exercise. Cell Metab 2013, 18:612-614.
22. Chan M.C., Arany Z. The many roles of PGC-1alpha in muscle-recent developments. Metabolism 2014, 63:441-451.
23. Little J.P., Safdar A., Cermak N.M., Tarnopolsky M.A., Gibala M.J. Acute endurance exercise increases the nuclear abundance of PGC-1alpha in trained human skeletal muscle. Am J Physiol Regul Integr Comp Physiol 2010, 298:R912-R917.
24. Trappe S., Hayes E., Galpin A., et al. New records in aerobic power among octogenarian lifelong endurance athletes. J Appl Physiol (1985) 2013, 114:3-10.
25. Vina J., Borras C., Sanchis-Gomar F., et al. Pharmacological properties of physical exercise in the elderly. Curr Pharm Des 2014, 20:3019-3029.
26. Handschin C., Spiegelman B.M. The role of exercise and PGC1alpha in inflammation and chronic disease. Nature 2008, 454:463-469.
27. Baker L.D., Frank L.L., Foster-Schubert K., et al. Aerobic exercise improves cognition for older adults with glucose intolerance: A risk factor for Alzheimer's disease. J Alzheimers Dis 2010, 22:569-579.
28. Wong-Goodrich S.J., Pfau M.L., Flores C.T., Fraser J.A., Williams C.L., Jones L.W. Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation. Cancer Res 2010, 70:9329-9338.
29. Jiang P., Dang R.L., Li H.D., et al. The impacts of swimming exercise on hippocampal expression of neurotrophic factors in rats exposed to chronic unpredictable mild stress. Evid Based Complement Alternat Med 2014, 2014:729827.
30. Jung S.Y., Kim D.Y., Yune T.Y., Shin D.H., Baek S.B., Kim C.J. Treadmill exercise reduces spinal cord injury-induced apoptosis by activating the PI3K/Akt pathway in rats. Exp Ther Med 2014, 7:587-593.
31. Koo H.M., Lee S.M., Kim M.H. Spontaneous wheel running exercise induces brain recovery via neurotrophin-3 expression following experimental traumatic brain injury in rats. J Phys Ther Sci 2013, 25:1103-1107.
32. Sharma N.K., Ryals J.M., Gajewski B.J., Wright D.E. Aerobic exercise alters analgesia and neurotrophin-3 synthesis in an animal model of chronic widespread pain. Phys Ther 2010, 90:714-725.
33. Ying Z., Roy R.R., Edgerton V.R., Gomez-Pinilla F. Exercise restores levels of neurotrophins and synaptic plasticity following spinal cord injury. Exp Neurol 2005, 193:411-419.
34. Fittipaldi S., Dimauro I., Mercatelli N., Caporossi D. Role of exercise-induced reactive oxygen species in the modulation of heat shock protein response. Free Radic Res 2014, 48:52-70.
35. Noble E.G., Milne K.J., Melling C.W. Heat shock proteins and exercise: A primer. Appl Physiol Nutr Metab 2008, 33:1050-1065.
36. Noble E.G., Shen G.X. Impact of exercise and metabolic disorders on heat shock proteins and vascular inflammation. Autoimmune Dis 2012, 2012:836519.
37. Ziemann E., Zembron-Lacny A., Kasperska A., et al. Exercise training-induced changes in inflammatory mediators and heat shock proteins in young tennis players. J Sports Sci Med 2013, 12:282-289.
38. Chung H.Y., Cesari M., Anton S., et al. Molecular inflammation: Underpinnings of aging and age-related diseases. Ageing Res Rev 2009, 8:18-30.
39. Metsios G.S., Stavropoulos-Kalinoglou A., Sandoo A., et al. Vascular function and inflammation in rheumatoid arthritis: The role of physical activity. Open Cardiovasc Med J 2010, 4:89-96.
40. Fleenor B.S., Marshall K.D., Durrant J.R., Lesniewski L.A., Seals D.R. Arterial stiffening with ageing is associated with transforming growth factor-beta1-related changes in adventitial collagen: Reversal by aerobic exercise. J Physiol 2010, 588(pt 20):3971-3982.
41. Mastorakos G., Ilias I. Interleukin-6: A cytokine and/or a major modulator of the response to somatic stress. Ann N Y Acad Sci 2006, 1088:373-381.
42. Kingwell B.A. Large artery stiffness: Implications for exercise capacity and cardiovascular risk. Clin Exp Pharmacol Physiol 2002, 29:214-217.
43. Maeda S., Iemitsu M., Miyauchi T., Kuno S., Matsuda M., Tanaka H. Aortic stiffness and aerobic exercise: Mechanistic insight from microarray analyses. Med Sci Sports Exerc 2005, 37:1710-1716.
44. Monahan K.D., Tanaka H., Dinenno F.A., Seals D.R. Central arterial compliance is associated with age- and habitual exercise-related differences in cardiovagal baroreflex sensitivity. Circulation 2001, 104:1627-1632.
45. Dart A.M., Kingwell B.A. Pulse pressure-a review of mechanisms and clinical relevance. J Am Coll Cardiol 2001, 37:975-984.
46. Bertovic D.A., Waddell T.K., Gatzka C.D., Cameron J.D., Dart A.M., Kingwell B.A. Muscular strength training is associated with low arterial compliance and high pulse pressure. Hypertension 1999, 33:1385-1391.
47. Miyachi M., Kawano H., Sugawara J., et al. Unfavorable effects of resistance training on central arterial compliance: A randomized intervention study. Circulation 2004, 110:2858-2863.
48. Cook J.N., DeVan A.E., Schleifer J.L., Anton M.M., Cortez-Cooper M.Y., Tanaka H. Arterial compliance of rowers: Implications for combined aerobic and strength training on arterial elasticity. Am J Physiol Heart Circ Physiol 2006, 290:H1596-H1600.
49. Nualnim N., Parkhurst K., Dhindsa M., Tarumi T., Vavrek J., Tanaka H. Effects of swimming training on blood pressure and vascular function in adults >50 years of age. Am J Cardiol 2012, 109:1005-1010.
50. Bobinski F., Martins D.F., Bratti T., et al. Neuroprotective and neuroregenerative effects of low-intensity aerobic exercise on sciatic nerve crush injury in mice. Neuroscience 2011, 194:337-348.
51. Yasuhara T., Hara K., Maki M., et al. Lack of exercise, via hindlimb suspension, impedes endogenous neurogenesis. Neuroscience 2007, 149:182-191.
52. Liebelt B., Papapetrou P., Ali A., et al. Exercise preconditioning reduces neuronal apoptosis in stroke by up-regulating heat shock protein-70 (heat shock protein-72) and extracellular-signal-regulated-kinase 1/2. Neuroscience 2010, 166:1091-1100.
53. Wrann C.D., White J.P., Salogiannnis J., et al. Exercise induces hippocampal BDNF through a PGC-1alpha/FNDC5 pathway. Cell Metab 2013, 18:649-659.
54. Kang E.B., Kwon I.S., Koo J.H., et al. Treadmill exercise represses neuronal cell death and inflammation during Aβ-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice. Apoptosis 2013, 18:1332-1347.
55. Hotting K., Roder B. Beneficial effects of physical exercise on neuroplasticity and cognition. Neurosci Biobehav Rev 2013, 37(9 pt B):2243-2257.
56. Gomez-Pinilla F., Hillman C. The influence of exercise on cognitive abilities. Compr Physiol 2013, 3:403-428.
57. Voss M.W., Nagamatsu L.S., Liu-Ambrose T., Kramer A.F. Exercise, brain, and cognition across the life span. J Appl Physiol (1985) 2011, 111:1505-1513.
58. van Boxtel M.P., Paas F.G., Houx P.J., Adam J.J., Teeken J.C., Jolles J. Aerobic capacity and cognitive performance in a cross-sectional aging study. Med Sci Sports Exerc 1997, 29:1357-1365.
59. Chapman S.B., Aslan S., Spence J.S., et al. Shorter term aerobic exercise improves brain, cognition, and cardiovascular fitness in aging. Front Aging Neurosci 2013, 5:75.
60. Ahlskog J.E., Geda Y.E., Graff-Radford N.R., Petersen R.C. Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging. Mayo Clin Proc 2011, 86:876-884.
61. Krause M., Rodrigues-Krause Jda C. Extracellular heat shock proteins (eHSP70) in exercise: Possible targets outside the immune system and their role for neurodegenerative disorders treatment. Med Hypotheses 2011, 76:286-290.
62. Tajiri N., Yasuhara T., Shingo T., et al. Exercise exerts neuroprotective effects on Parkinson's disease model of rats. Brain Res 2010, 1310:200-207.
63. Tabak R., Aquije G., Fisher B.E. Aerobic exercise to improve executive function in Parkinson disease: A case series. J Neurol Phys Ther 2013, 37:58-64.
64. McDonnell M.N., Smith A.E., Mackintosh S.F. Aerobic exercise to improve cognitive function in adults with neurological disorders: A systematic review. Arch Phys Med Rehabil 2011, 92:1044-1052.
65. Yu F., Kolanowski A.M., Strumpf N.E., Eslinger P.J. Improving cognition and function through exercise intervention in Alzheimer's disease. J Nurs Scholarsh 2006, 38:358-365.
66. Briken S., Gold S.M., Patra S., et al. Effects of exercise on fitness and cognition in progressive MS: A randomized, controlled pilot trial. Mult Scler 2014, 20:382-390.
67. Motl R.W., Pilutti L.A. The benefits of exercise training in multiple sclerosis. Nat Rev Neurol 2012, 8:487-497.
68. Prakash R.S., Snook E.M., Erickson K.I., et al. Cardiorespiratory fitness: A predictor of cortical plasticity in multiple sclerosis. Neuroimage 2007, 34:1238-1244.
69. Voss M.W., Heo S., Prakash R.S., et al. The influence of aerobic fitness on cerebral white matter integrity and cognitive function in older adults: Results of a one-year exercise intervention. Human Brain Mapp 2013, 34:2972-2985.
70. Iizuka K., Machida T., Hirafuji M. Skeletal muscle is an endocrine organ. J Pharmacol Sci 2014, 125:125-131.
71. Konopka A.R., Suer M.K., Wolff C.A., Harber M.P. Markers of human skeletal muscle mitochondrial biogenesis and quality control: Effects of age and aerobic exercise training. J Gerontol A Biol Sci Med Sci 2014, 69:371-378.
72. Broskey N.T., Greggio C., Boss A., et al. Skeletal muscle mitochondria in the elderly: Effects of physical fitness and exercise training. J Clin Endocrinol Metab 2014, 99:1852-1861.
73. Marzetti E., Calvani R., Cesari M., et al. Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials. Int J Biochem Cell Biol 2013, 45:2288-2301.
74. Grounds M.D. Age-associated changes in the response of skeletal muscle cells to exercise and regeneration. Ann N Y Acad Sci 1998, 854:78-91.
75. Verdijk L.B., Snijders T., Drost M., Delhaas T., Kadi F., van Loon L.J. Satellite cells in human skeletal muscle; from birth to old age. Age (Dordr) 2014, 36:545-547.
76. Abruzzo P.M., Esposito F., Marchionni C., et al. Moderate exercise training induces ROS-related adaptations to skeletal muscles. Int J Sports Med 2013, 34:676-687.
77. Gavin TP, Kraus RM, Carrithers JA, Garry JP, Hickner RC. Aging and the skeletal muscle angiogenic response to exercise in women [published online ahead of print September 2, 2014]. J Gerontol A Biol Sci Med Sci.
78. Petersen A.M., Pedersen B.K. The anti-inflammatory effect of exercise. J Appl Physiol (1985) 2005, 98:1154-1162.