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Volumn 194, Issue , 2011, Pages 337-348

Neuroprotective and neuroregenerative effects of low-intensity aerobic exercise on sciatic nerve crush injury in mice

Author keywords

Functional recovery; Hypersensitivity; Nerve regeneration; Neuroprotection; Physical exercise

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 80053123694     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.07.075     Document Type: Article
Times cited : (98)

References (64)
  • 1
    • 0023272854 scopus 로고
    • Effects of endurance exercise on the morphology of mouse neuromuscular junctions during ageing
    • Andonian M.H., Fahim M.A. Effects of endurance exercise on the morphology of mouse neuromuscular junctions during ageing. J Neurocytol 1987, 16:589-599.
    • (1987) J Neurocytol , vol.16 , pp. 589-599
    • Andonian, M.H.1    Fahim, M.A.2
  • 2
    • 0024498021 scopus 로고
    • Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat
    • Bain J.R., Mackinnon S.E., Hunter D.A. Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat. Plast Reconstr Surg 1989, 83:129-138.
    • (1989) Plast Reconstr Surg , vol.83 , pp. 129-138
    • Bain, J.R.1    Mackinnon, S.E.2    Hunter, D.A.3
  • 4
    • 0023895875 scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • Bennett G.J., Xie Y.K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 1988, 33:87-107.
    • (1988) Pain , vol.33 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.K.2
  • 5
    • 0037174794 scopus 로고    scopus 로고
    • Anti-allodynic action of the tormentic acid, a triterpene isolated from plant, against neuropathic and inflammatory persistent pain in mice
    • Bortalanza L.B., Ferreira J., Hess S.C., Delle Monache F., Yunes R.A., Calixto J.B. Anti-allodynic action of the tormentic acid, a triterpene isolated from plant, against neuropathic and inflammatory persistent pain in mice. Eur J Pharmacol 2002, 453:203-208.
    • (2002) Eur J Pharmacol , vol.453 , pp. 203-208
    • Bortalanza, L.B.1    Ferreira, J.2    Hess, S.C.3    Delle Monache, F.4    Yunes, R.A.5    Calixto, J.B.6
  • 6
    • 0031427410 scopus 로고    scopus 로고
    • Neurotropic factors increase axonal growth after spinal cord injury and transplantation in the adult rat
    • Bregman B.S., McAtee M., Dai H.N., Kuhn P.L. Neurotropic factors increase axonal growth after spinal cord injury and transplantation in the adult rat. Exp Neurol 1997, 148:475-494.
    • (1997) Exp Neurol , vol.148 , pp. 475-494
    • Bregman, B.S.1    McAtee, M.2    Dai, H.N.3    Kuhn, P.L.4
  • 8
    • 64249119331 scopus 로고    scopus 로고
    • Nociceptive responses and spinal plastic changes of afferent C-fibers in three neuropathic pain models induced by sciatic nerve injury in the rat
    • Casals-Díaz L., Vivó M., Navarro X. Nociceptive responses and spinal plastic changes of afferent C-fibers in three neuropathic pain models induced by sciatic nerve injury in the rat. Exp Neurol 2009, 217:84-89.
    • (2009) Exp Neurol , vol.217 , pp. 84-89
    • Casals-Díaz, L.1    Vivó, M.2    Navarro, X.3
  • 9
    • 0035807876 scopus 로고    scopus 로고
    • Neurotrophins are key mediators of the myelination program in the peripheral nervous system
    • Chan J.R., Cosgaya J.M., Wu Y.J., Shooter E.M. Neurotrophins are key mediators of the myelination program in the peripheral nervous system. Proc Natl Acad Sci U S A 2001, 98:14661-14668.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14661-14668
    • Chan, J.R.1    Cosgaya, J.M.2    Wu, Y.J.3    Shooter, E.M.4
  • 10
    • 77952890894 scopus 로고    scopus 로고
    • Short-but not long-lasting treadmill running reduces allodynia and improves functional recovery after peripheral nerve injury
    • Cobianchi S., Marinelli S., Florenzano F., Pavone F., Luvisetto S. Short-but not long-lasting treadmill running reduces allodynia and improves functional recovery after peripheral nerve injury. Neuroscience 2010, 168:273-287.
    • (2010) Neuroscience , vol.168 , pp. 273-287
    • Cobianchi, S.1    Marinelli, S.2    Florenzano, F.3    Pavone, F.4    Luvisetto, S.5
  • 11
    • 0032702435 scopus 로고    scopus 로고
    • Preclinical testing of neuroprotective neurotrophic factors in a model of chronic motor neuron degeneration
    • Corse A.M., Bilak M.M., Bilak S.R., Lehar M., Rothstein J.D., Kuncl R.W. Preclinical testing of neuroprotective neurotrophic factors in a model of chronic motor neuron degeneration. Neurobiol Dis 1999, 6:335-346.
    • (1999) Neurobiol Dis , vol.6 , pp. 335-346
    • Corse, A.M.1    Bilak, M.M.2    Bilak, S.R.3    Lehar, M.4    Rothstein, J.D.5    Kuncl, R.W.6
  • 12
    • 60849110550 scopus 로고    scopus 로고
    • Specific effects of acute moderate exercise on cognitive control
    • Davranche K., McMorris T. Specific effects of acute moderate exercise on cognitive control. Brain Cogn 2009, 69:565-570.
    • (2009) Brain Cogn , vol.69 , pp. 565-570
    • Davranche, K.1    McMorris, T.2
  • 13
    • 0019938340 scopus 로고
    • An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks
    • de Medinaceli L., Freed W.J., Wyatt R.J. An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks. Exp Neurol 1982, 77:634-643.
    • (1982) Exp Neurol , vol.77 , pp. 634-643
    • de Medinaceli, L.1    Freed, W.J.2    Wyatt, R.J.3
  • 16
    • 0025858777 scopus 로고
    • Effects of enhanced activity on synaptic transmission in mouse extensor digitorum longus muscle
    • Dorlochter M., Irintchev A., Brinkers M., Wernig A. Effects of enhanced activity on synaptic transmission in mouse extensor digitorum longus muscle. J Physiol 1991, 436:283-292.
    • (1991) J Physiol , vol.436 , pp. 283-292
    • Dorlochter, M.1    Irintchev, A.2    Brinkers, M.3    Wernig, A.4
  • 18
    • 51449113407 scopus 로고    scopus 로고
    • Evaluation methods in the assessment of peripheral nerve regeneration
    • Geuna S., Varejão A.S. Evaluation methods in the assessment of peripheral nerve regeneration. J Neurosurg 2008, 109:360-362.
    • (2008) J Neurosurg , vol.109 , pp. 360-362
    • Geuna, S.1    Varejão, A.S.2
  • 19
    • 0035064497 scopus 로고    scopus 로고
    • Differential regulation by exercise of BDNF and NT-3 in rat spinal cord and skeletal muscle
    • Gómez-Pinilla F., Ying Z., Opazo P., Roy R.R., Edgerton V.R. Differential regulation by exercise of BDNF and NT-3 in rat spinal cord and skeletal muscle. Eur J Neurosci 2001, 13:1078-1084.
    • (2001) Eur J Neurosci , vol.13 , pp. 1078-1084
    • Gómez-Pinilla, F.1    Ying, Z.2    Opazo, P.3    Roy, R.R.4    Edgerton, V.R.5
  • 20
    • 69049114964 scopus 로고    scopus 로고
    • Exercise-induced improvement in cognitive performance after traumatic brain injury in rats is dependent on BDNF activation
    • Griesbach G.S., Hovda D.A., Gomez-Pinilla F. Exercise-induced improvement in cognitive performance after traumatic brain injury in rats is dependent on BDNF activation. Brain Res 2009, 1288:105-115.
    • (2009) Brain Res , vol.1288 , pp. 105-115
    • Griesbach, G.S.1    Hovda, D.A.2    Gomez-Pinilla, F.3
  • 23
    • 0018876287 scopus 로고
    • Histochemical fiber type alterations secondary to exercise training of reinnervating adult rat muscle
    • Herbison G.J., Jaweed M.M., Ditunno J.F. Histochemical fiber type alterations secondary to exercise training of reinnervating adult rat muscle. Arch Phys Med Rehabil 1980, 61:255-257.
    • (1980) Arch Phys Med Rehabil , vol.61 , pp. 255-257
    • Herbison, G.J.1    Jaweed, M.M.2    Ditunno, J.F.3
  • 24
    • 0019159014 scopus 로고
    • Effect of activity and inactivity on reinnervating rat skeletal muscle contractility
    • Herbison G.J., Jaweed M.M., Ditunno J.F. Effect of activity and inactivity on reinnervating rat skeletal muscle contractility. Exp Neurol 1980, 70:498-506.
    • (1980) Exp Neurol , vol.70 , pp. 498-506
    • Herbison, G.J.1    Jaweed, M.M.2    Ditunno, J.F.3
  • 27
    • 0031869497 scopus 로고    scopus 로고
    • Repair with collagen tubules linked with brain derived neurotrophic factor and ciliary neurotrophic factor in a rat sciatic nerve injury model
    • Ho P.R., Coan G.M., Cheng E.T., Niell C., Tarn D.M., Zhou H., Sierra D., Terris D.J. Repair with collagen tubules linked with brain derived neurotrophic factor and ciliary neurotrophic factor in a rat sciatic nerve injury model. Arch Otolaryngol Head Neck Surg 1998, 124:761-766.
    • (1998) Arch Otolaryngol Head Neck Surg , vol.124 , pp. 761-766
    • Ho, P.R.1    Coan, G.M.2    Cheng, E.T.3    Niell, C.4    Tarn, D.M.5    Zhou, H.6    Sierra, D.7    Terris, D.J.8
  • 28
    • 45449098534 scopus 로고    scopus 로고
    • Endurance and resistance exercise training programs elicit specific effects on sciatic nerve regeneration after experimental traumatic lesion in rats
    • Ilha J., Araujo R.T., Malysz T., Hermel E.E., Rigon P., Xavier L.L., Achaval M. Endurance and resistance exercise training programs elicit specific effects on sciatic nerve regeneration after experimental traumatic lesion in rats. Neurorehabil Neural Repair 2008, 22:355-366.
    • (2008) Neurorehabil Neural Repair , vol.22 , pp. 355-366
    • Ilha, J.1    Araujo, R.T.2    Malysz, T.3    Hermel, E.E.4    Rigon, P.5    Xavier, L.L.6    Achaval, M.7
  • 29
    • 0031750867 scopus 로고    scopus 로고
    • Functional indices for sciatic, peroneal, and posterior tibial nerve lesions in the mouse
    • Inserra M.M., Bloch D.A., Terris D.J. Functional indices for sciatic, peroneal, and posterior tibial nerve lesions in the mouse. Microsurgery 1998, 18:119-124.
    • (1998) Microsurgery , vol.18 , pp. 119-124
    • Inserra, M.M.1    Bloch, D.A.2    Terris, D.J.3
  • 30
    • 0036824699 scopus 로고    scopus 로고
    • Activity of medullary serotonergic neurons in freely moving animals
    • Jacobs B.L., Martin-Cora F.J., Fornal C.A. Activity of medullary serotonergic neurons in freely moving animals. Brain Res Rev 2002, 40:45-52.
    • (2002) Brain Res Rev , vol.40 , pp. 45-52
    • Jacobs, B.L.1    Martin-Cora, F.J.2    Fornal, C.A.3
  • 31
    • 0034176506 scopus 로고    scopus 로고
    • A new animal model for assessing mechanisms and management of muscle hyperalgesia
    • Kehl L.J., Trempe T.M., Hargreaves K.M. A new animal model for assessing mechanisms and management of muscle hyperalgesia. Pain 2000, 85:333-343.
    • (2000) Pain , vol.85 , pp. 333-343
    • Kehl, L.J.1    Trempe, T.M.2    Hargreaves, K.M.3
  • 32
    • 0033963097 scopus 로고    scopus 로고
    • Analgesia following exercise: a review
    • Koltyn K.F. Analgesia following exercise: a review. Sports Med 2000, 29:85-98.
    • (2000) Sports Med , vol.29 , pp. 85-98
    • Koltyn, K.F.1
  • 33
    • 76849092538 scopus 로고    scopus 로고
    • Effect of treadmill exercise on serotonin immunoreactivity in medullary raphe nuclei and spinal cord following sciatic nerve transection in rats
    • Korb A., Bonetti L.V., da Silva S.A., Marcuzzo S., Ilha J., Bertagnolli M., Partata W.A., Faccioni-Heuser M.C. Effect of treadmill exercise on serotonin immunoreactivity in medullary raphe nuclei and spinal cord following sciatic nerve transection in rats. Neurochem Res 2010, 35:380-389.
    • (2010) Neurochem Res , vol.35 , pp. 380-389
    • Korb, A.1    Bonetti, L.V.2    da Silva, S.A.3    Marcuzzo, S.4    Ilha, J.5    Bertagnolli, M.6    Partata, W.A.7    Faccioni-Heuser, M.C.8
  • 34
    • 0030741376 scopus 로고    scopus 로고
    • Simultaneous treatment with BDNF and CNTF after peripheral nerve transection and repair enhances rate of functional recovery compared with BDNF-treatment alone
    • Lewin S.L., Utley D.S., Cheng E.T., Verity A.N., Terris D.J. Simultaneous treatment with BDNF and CNTF after peripheral nerve transection and repair enhances rate of functional recovery compared with BDNF-treatment alone. Laryngoscope 1997, 107:992-999.
    • (1997) Laryngoscope , vol.107 , pp. 992-999
    • Lewin, S.L.1    Utley, D.S.2    Cheng, E.T.3    Verity, A.N.4    Terris, D.J.5
  • 35
    • 2342456468 scopus 로고    scopus 로고
    • Neuromuscular rehabilitation by treadmill running or electrical stimulation after peripheral nerve injury and repair
    • Marqueste T., Alliez J.R., Alluin O., Jammes Y., Decherchi P. Neuromuscular rehabilitation by treadmill running or electrical stimulation after peripheral nerve injury and repair. J Appl Physiol 2004, 96:1988-1995.
    • (2004) J Appl Physiol , vol.96 , pp. 1988-1995
    • Marqueste, T.1    Alliez, J.R.2    Alluin, O.3    Jammes, Y.4    Decherchi, P.5
  • 38
    • 0032513319 scopus 로고    scopus 로고
    • Hyperinnervation of neuromuscular junctions caused by GDNF overexpression in muscle
    • Nguyen Q.T., Parsadanian A.S., Snider W.D., Lichtman J.W. Hyperinnervation of neuromuscular junctions caused by GDNF overexpression in muscle. Science 1998, 279:1725-1729.
    • (1998) Science , vol.279 , pp. 1725-1729
    • Nguyen, Q.T.1    Parsadanian, A.S.2    Snider, W.D.3    Lichtman, J.W.4
  • 39
    • 0028874195 scopus 로고
    • Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF
    • Oppenheim R.W., Houenou L.J., Johnson J.E. Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature 1995, 373:344-346.
    • (1995) Nature , vol.373 , pp. 344-346
    • Oppenheim, R.W.1    Houenou, L.J.2    Johnson, J.E.3
  • 40
    • 33745728124 scopus 로고    scopus 로고
    • Depletion of endogenous spinal 5HT attenuates the behavioral hypersensitivity to mechanical cooling stimuli induced by spinal nerve ligation
    • Rahman W., Suzuki R., Webber M., Hunt S.P., Dickenson A.H. Depletion of endogenous spinal 5HT attenuates the behavioral hypersensitivity to mechanical cooling stimuli induced by spinal nerve ligation. Pain 2006, 123:264-274.
    • (2006) Pain , vol.123 , pp. 264-274
    • Rahman, W.1    Suzuki, R.2    Webber, M.3    Hunt, S.P.4    Dickenson, A.H.5
  • 41
    • 70349783205 scopus 로고    scopus 로고
    • Methods and protocols in peripheral nerve regeneration experimental research: part II-morphological techniques
    • Raimondo S., Fornaro M., Di Scipio F., Ronchi G., Giacobini-Robecchi M.G., Geuna S. Methods and protocols in peripheral nerve regeneration experimental research: part II-morphological techniques. Int Rev Neurobiol 2009, 87:81-103.
    • (2009) Int Rev Neurobiol , vol.87 , pp. 81-103
    • Raimondo, S.1    Fornaro, M.2    Di Scipio, F.3    Ronchi, G.4    Giacobini-Robecchi, M.G.5    Geuna, S.6
  • 43
    • 45849118673 scopus 로고    scopus 로고
    • Alarm or curse?. The pain of neuroinflammation
    • Saab C.Y., Waxman S.G., Hains B.C. Alarm or curse?. The pain of neuroinflammation. Brain Res Rev 2008, 58:226-235.
    • (2008) Brain Res Rev , vol.58 , pp. 226-235
    • Saab, C.Y.1    Waxman, S.G.2    Hains, B.C.3
  • 44
    • 43449106180 scopus 로고    scopus 로고
    • Treadmill training promotes axon regeneration in injured peripheral nerves
    • Sabatier M.J., Redmon N., Schwartz G., English A.W. Treadmill training promotes axon regeneration in injured peripheral nerves. Exp Neurol 2008, 211:489-493.
    • (2008) Exp Neurol , vol.211 , pp. 489-493
    • Sabatier, M.J.1    Redmon, N.2    Schwartz, G.3    English, A.W.4
  • 45
    • 0029950147 scopus 로고    scopus 로고
    • GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice
    • Sagot Y., Tan S.A., Hammang J.P., Aebischer P., Kato A.C. GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice. J Neurosci 1996, 16:2335-2341.
    • (1996) J Neurosci , vol.16 , pp. 2335-2341
    • Sagot, Y.1    Tan, S.A.2    Hammang, J.P.3    Aebischer, P.4    Kato, A.C.5
  • 46
    • 35548937457 scopus 로고    scopus 로고
    • The neuropathic pain triad: neurons, immune cells and glia
    • Scholz J., Woolf C.J. The neuropathic pain triad: neurons, immune cells and glia. Nat Neurosci 2007, 10:1361-1368.
    • (2007) Nat Neurosci , vol.10 , pp. 1361-1368
    • Scholz, J.1    Woolf, C.J.2
  • 47
    • 0035863085 scopus 로고    scopus 로고
    • Increased neuromuscular activity reduces sprouting in partially denervated muscles
    • Tam S.L., Archibald V., Jassar B., Tyreman N., Gordon T. Increased neuromuscular activity reduces sprouting in partially denervated muscles. J Neurosci 2001, 21:654-667.
    • (2001) J Neurosci , vol.21 , pp. 654-667
    • Tam, S.L.1    Archibald, V.2    Jassar, B.3    Tyreman, N.4    Gordon, T.5
  • 48
    • 0027322508 scopus 로고
    • Individual anaerobic threshold and maximum lactate steady state
    • Urhausen A., Coen B., Weiler B., Kindermann W. Individual anaerobic threshold and maximum lactate steady state. Int J Sports Med 1993, 14:134-139.
    • (1993) Int J Sports Med , vol.14 , pp. 134-139
    • Urhausen, A.1    Coen, B.2    Weiler, B.3    Kindermann, W.4
  • 49
    • 0031013425 scopus 로고    scopus 로고
    • Exercise training improves functional recovery and motor nerve conduction velocity after sciatic nerve crush lesion in the rat
    • van Meeteren N.L., Brakkee J.H., Hamers F.P., Helders P.J., Gispen W.H. Exercise training improves functional recovery and motor nerve conduction velocity after sciatic nerve crush lesion in the rat. Arch Phys Med Rehabil 1997, 78:70-77.
    • (1997) Arch Phys Med Rehabil , vol.78 , pp. 70-77
    • van Meeteren, N.L.1    Brakkee, J.H.2    Hamers, F.P.3    Helders, P.J.4    Gispen, W.H.5
  • 50
    • 0031726333 scopus 로고    scopus 로고
    • The effect of exercise training on functional recovery after sciatic nerve crush in the rat
    • van Meeteren N.L., Brakkee J.H., Helders P.J., Gispen W.H. The effect of exercise training on functional recovery after sciatic nerve crush in the rat. J Peripher Nerv Syst 1998, 3:277-282.
    • (1998) J Peripher Nerv Syst , vol.3 , pp. 277-282
    • van Meeteren, N.L.1    Brakkee, J.H.2    Helders, P.J.3    Gispen, W.H.4
  • 51
  • 52
    • 0030985238 scopus 로고    scopus 로고
    • Single-unit responses of serotonergic dorsal raphe neurons to specific motor challenges in freely moving cats
    • Veasey S.C., Fornal C.A., Metzler C.W., Jacobs B.L. Single-unit responses of serotonergic dorsal raphe neurons to specific motor challenges in freely moving cats. Neuroscience 1997, 79:161-169.
    • (1997) Neuroscience , vol.79 , pp. 161-169
    • Veasey, S.C.1    Fornal, C.A.2    Metzler, C.W.3    Jacobs, B.L.4
  • 53
    • 33750736086 scopus 로고    scopus 로고
    • Acute BDNF and cortisol response to low intensity exercise and following ramp incremental exercise to exhaustion in humans
    • Vega S.R., Strüder H.K., Wahrmann B.V., Schmidt A., Bloch W., Hollmann W. Acute BDNF and cortisol response to low intensity exercise and following ramp incremental exercise to exhaustion in humans. Brain Res 2006, 1121:59-65.
    • (2006) Brain Res , vol.1121 , pp. 59-65
    • Vega, S.R.1    Strüder, H.K.2    Wahrmann, B.V.3    Schmidt, A.4    Bloch, W.5    Hollmann, W.6
  • 54
    • 33745279379 scopus 로고    scopus 로고
    • Effects of local continuous release of brain derived neurotrophic factor (BDNF) on peripheral nerve regeneration in a rat model
    • Vögelin E., Baker J.M., Gates J., Dixit V., Constantinescu M.A., Jones N.F. Effects of local continuous release of brain derived neurotrophic factor (BDNF) on peripheral nerve regeneration in a rat model. Exp Neurol 2006, 199:348-353.
    • (2006) Exp Neurol , vol.199 , pp. 348-353
    • Vögelin, E.1    Baker, J.M.2    Gates, J.3    Dixit, V.4    Constantinescu, M.A.5    Jones, N.F.6
  • 55
    • 77954900245 scopus 로고    scopus 로고
    • No synergistic effect of mesenchymal stem cells and exercise on functional recovery following sciatic nerve transection
    • Wang J., Yang C.C., Chen S.C., Hsieh Y.L. No synergistic effect of mesenchymal stem cells and exercise on functional recovery following sciatic nerve transection. Funct Neurol 2010, 25:33-43.
    • (2010) Funct Neurol , vol.25 , pp. 33-43
    • Wang, J.1    Yang, C.C.2    Chen, S.C.3    Hsieh, Y.L.4
  • 56
    • 0034882399 scopus 로고    scopus 로고
    • Spinal cord glia: new players in pain
    • Watkins L.R., Milligan E.D., Maier S.F. Spinal cord glia: new players in pain. Pain 2001, 93:201-205.
    • (2001) Pain , vol.93 , pp. 201-205
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 57
    • 0036334879 scopus 로고    scopus 로고
    • GDNF is regulated in an activity-dependent manner in rat skeletal muscle
    • Wehrwein E.A., Roskelley E.M., Spitsbergen J.M. GDNF is regulated in an activity-dependent manner in rat skeletal muscle. Muscle Nerve 2002, 26:206-211.
    • (2002) Muscle Nerve , vol.26 , pp. 206-211
    • Wehrwein, E.A.1    Roskelley, E.M.2    Spitsbergen, J.M.3
  • 59
    • 0018889218 scopus 로고
    • The effects of swimming in mice on pain perception and sleeping time in response to hypnotic drugs
    • Willow M., Carmody J., Carroll P. The effects of swimming in mice on pain perception and sleeping time in response to hypnotic drugs. Life Sci 1980, 26:219-224.
    • (1980) Life Sci , vol.26 , pp. 219-224
    • Willow, M.1    Carmody, J.2    Carroll, P.3
  • 60
    • 84970985955 scopus 로고    scopus 로고
    • World Health Organization
    • Health topics: physical activity World Health Organization. http://www.who.int/topics/physical_activity/en/.
    • Health topics: physical activity
  • 62
  • 63
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16:109-110.
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1


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