Herceptin conjugated PLGA-PHis-PEG pH sensitive nanoparticles for targeted and controlled drug delivery

International Journal of Pharmaceutics

Volumn 487, Issue 1-2, 2015, Pages 81-90

  Zhou, Zilan ^a   Badkas, Apurva ^a   Stevenson, Max ^b   Lee, Joo Youp ^a   Leung, Yuet Kin ^b  

^a 705 Engineering Research Center   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Active targeting; Breast cancer; Herceptin ; pH sensitivity; Polymeric nanoparticles

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; MACROGOL; NANOPARTICLE; POLYGLACTIN; POLYHISTIDINE; TRASTUZUMAB; ANTINEOPLASTIC AGENT; DRUG CARRIER; ERBB2 PROTEIN, HUMAN; HISTIDINE; LACTIC ACID; MACROGOL DERIVATIVE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ARTICLE; BREAST CANCER CELL LINE; CLICK CHEMISTRY; CONFOCAL LASER MICROSCOPY; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DYNAMIC LIGHT SCATTERING; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGHT SCATTERING; MCF 7 CELL LINE; PARTICLE SIZE; PH; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; CHEMISTRY; FEMALE; LYSOSOME; MEDICINAL CHEMISTRY; METABOLISM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; HISTIDINE; HUMANS; LACTIC ACID; LYSOSOMES; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; RECEPTOR, ERBB-2; TRASTUZUMAB;

EID: 84927731233     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.03.081     Document Type: Article

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