A simple method to achieve high doxorubicin loading in biodegradable polymersomes

Journal of Controlled Release

Volumn 147, Issue 3, 2010, Pages 428-435

  Sanson, Charles ^a   Schatz, Christophe ^a   Le Meins, Jean François ^a   Soum, Alain ^a   Thévenot, Julie ^a   Garanger, Elisabeth ^b   Lecommandoux, SébastienSe ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b UNIVERSITÉ BORDEAUX 1   (France)

Author keywords

Block copolymer; Controlled release; Doxorubicin; Drug delivery; Polymersome; Vesicle

Indexed keywords

ACID CONDITIONS; ANTICANCER DRUG; AQUEOUS DISPERSIONS; BLOCK COPOLYMER VESICLES; CONTROLLED DELIVERY; CONTROLLED RELEASE; DOXORUBICIN; DRUG LOADING; DRUG RELEASE; IN-VITRO; L-GLUTAMIC ACIDS; LOADING CAPACITIES; NANOPRECIPITATION; PH CONDITION; POLY(TRIMETHYLENE CARBONATE); POLYMERSOMES; RELEASE KINETICS; RELEASE PROFILES; SIMPLE METHOD; TEMPERATURE DEPENDENT; VESICLE;

AMINO ACIDS; BIODEGRADABLE POLYMERS; BLOCK COPOLYMERS; COPOLYMERIZATION; LOADING;

CONTROLLED DRUG DELIVERY;

DOXORUBICIN; GLUTAMIC ACID; POLY(TRIMETHYLENE CARBONATE) B POLY(LEVO GLUTAMIC ACID); UNCLASSIFIED DRUG;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STABILITY; DRUG STRUCTURE; IN VITRO STUDY; PRECIPITATION; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY;

ANTIBIOTICS, ANTINEOPLASTIC; CHEMICAL PRECIPITATION; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIOXANES; DOXORUBICIN; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, CHEMICAL; NANOTECHNOLOGY; POLYGLUTAMIC ACID; POLYMERS; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

EID: 78049473646     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.07.123     Document Type: Article

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