PH-responsive and charge shielded cationic micelle of poly(l-histidine)- block-short branched PEI for acidic cancer treatment

Journal of Controlled Release

Volumn 172, Issue 1, 2013, Pages 69-76

  Hu, Jun ^a   Miura, Seiji ^b   Na, Kun ^c   Bae, You Han ^a,b,d  

^a UNIVERSITY OF UTAH   (United States)

^b KOWA COMPANY LTD   (Japan)

^c The Catholic University of Korea   (South Korea)

^d Utah Inha DDS and Advanced Therapeutics   (South Korea)

Author keywords

Extracellular pH; Micelle; Paclitaxel; pH sensitive block copolymer; Poly(l histidine); Tumor heterogeneity

Indexed keywords

EXTRACELLULAR PH; PACLITAXEL; PH SENSITIVE; POLIES (LHISTIDINE); TUMOR HETEROGENEITY;

AMINO ACIDS; BLOCK COPOLYMERS; CELL CULTURE; CELLS; DISEASES; MOTION PICTURE EXPERTS GROUP STANDARDS; TUMORS;

MICELLES;

CATION; COPOLYMER; PACLITAXEL; POLYETHYLENEIMINE; POLYHISTIDINE;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CANCER INHIBITION; CANCER THERAPY; DRUG CYTOTOXICITY; DRUG PENETRATION; DRUG TUMOR LEVEL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICELLE; MOUSE; NONHUMAN; OVARY CARCINOMA; PH; PRIORITY JOURNAL; STATIC ELECTRICITY; SURFACE CHARGE; SURFACE PROPERTY; TUMOR VOLUME; TUMOR XENOGRAFT; WILD TYPE;

EXTRACELLULAR PH; MICELLE; PACLITAXEL; PH-SENSITIVE BLOCK COPOLYMER; POLY(L-HISTIDINE); TUMOR HETEROGENEITY;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL LINE, TUMOR; DELAYED-ACTION PREPARATIONS; FEMALE; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; MICE, INBRED BALB C; MICE, NUDE; OVARIAN NEOPLASMS; PACLITAXEL; POLYETHYLENEIMINE;

EID: 84883506356     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.08.007     Document Type: Article

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