Self-assembled pH-responsive MPEG-b-(PLA-co-PAE) block copolymer micelles for anticancer drug delivery

Biomaterials

Volumn 33, Issue 26, 2012, Pages 6273-6283

  Zhang, Can Yang ^a   Yang, You Qiang ^a   Huang, Tu Xiong ^a   Zhao, Bin ^a   Guo, Xin Dong ^a   Wang, Ju Fang ^a   Zhang, Li Juan ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Amphiphilic copolymer; Drug delivery; Micelle; PH responsive; Poly ( amino esters)

Indexed keywords

AMINO ESTERS; AMINO GROUP; AMPHIPHILIC COPOLYMERS; AMPHIPHILICS; ANTI-CANCER DRUG DELIVERY; AVERAGE PARTICLE SIZE; BLOCK COPOLYMER MICELLES; CANCER-TARGETING; CORE/SHELL; CRITICAL MICELLE CONCENTRATION (CMC); DOXORUBICIN; DRUG LOADING; FICKIAN DIFFUSION MECHANISM; HEPG2 CELLS; HYDROPHOBIC DRUG DELIVERY; IN-VITRO; LOW CONCENTRATIONS; LOW TOXICITY; PH SENSITIVE; PH-RESPONSIVE; POSITIVELY CHARGED; SELF-ASSEMBLE; SELF-ASSEMBLED; SOLUTION PH; SUSTAINED RELEASE; TOXICITY TEST;

BLOCK COPOLYMERS; CELL CULTURE; CRITICAL MICELLE CONCENTRATION; CYTOTOXICITY; DRUG DELIVERY; ESTERIFICATION; ESTERS; ETHERS; GEL PERMEATION CHROMATOGRAPHY; LACTIC ACID; LOADING; MOTION PICTURE EXPERTS GROUP STANDARDS; POLYETHYLENE GLYCOLS; ZETA POTENTIAL;

MICELLES;

COPOLYMER; DIMETHYL ETHER; DOXORUBICIN; MACROGOL; POLY(BETA AMINO ESTER); POLYLACTIC ACID; UNCLASSIFIED DRUG; WATER;

ACCELERATION; AQUEOUS SOLUTION; ARTICLE; CELL STRAIN HEPG2; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CRITICAL MICELLE CONCENTRATION; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; GEL PERMEATION CHROMATOGRAPHY; HYDROPHOBICITY; IN VITRO STUDY; MICELLE; MICHAEL ADDITION; PARTICLE SIZE; PH; POLYMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; ZETA POTENTIAL;

DRUG CARRIERS; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; LACTIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; POLYETHYLENE GLYCOLS; POLYMERS;

EID: 84862878268     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.05.025     Document Type: Article

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