Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity

EMBO Journal

Volumn 33, Issue 23, 2014, Pages 2765-2781

  Jaworski, Maike ^a   Marsland, Ben J ^b   Gehrig, Jasmine ^a   Held, Werner ^a   Favre, Stéphanie ^a   Luther, Sanjiv A ^a   Perroud, Mai ^a   Golshayan, Déla ^b   Gaide, Olivier ^b   Thome, Margot ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

colitis; EAE; gastritis; NF B; paracaspase

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; MALT1 PROTEIN; PROTEINASE; UNCLASSIFIED DRUG; CASPASE; DNA BINDING PROTEIN; IMMUNOGLOBULIN G; MALT1 PROTEIN, MOUSE; PRIMER DNA; RAG2 PROTEIN, MOUSE; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; COLITIS; CONTROLLED STUDY; DENDRITIC CELL; EMBRYO; ENZYME ACTIVITY; ENZYME MECHANISM; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GASTRITIS; IMMUNE RESPONSE; IN VIVO STUDY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; ADOPTIVE TRANSFER; ANALYSIS OF VARIANCE; ANIMAL; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; GENE TARGETING; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; POINT MUTATION; REAL TIME POLYMERASE CHAIN REACTION;

MUS;

ADOPTIVE TRANSFER; ANALYSIS OF VARIANCE; ANIMALS; AUTOIMMUNITY; CASPASES; COLITIS; DNA PRIMERS; DNA-BINDING PROTEINS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCK-IN TECHNIQUES; GENE SILENCING; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; KILLER CELLS, NATURAL; MICE; MICE, KNOCKOUT; NEOPLASM PROTEINS; POINT MUTATION; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84919336458     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201488987     Document Type: Article

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