Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance

EMBO Journal

Volumn 31, Issue 23, 2012, Pages 4453-4465

  Kasler, Herbert G ^a   Lim, Hyung W ^a   Mottet, Denis ^a,b   Collins, Amy M ^a   Lee, Intelly S ^a   Verdin, Eric ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Metastasis Research Laboratory   (Belgium)

Author keywords

autoimmunity; gene regulation; histone deacetylase; T cell development; thymic selection

Indexed keywords

HISTONE DEACETYLASE 7; MITOGEN ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CELL NUCLEUS TRANSPLANTATION; CELL SELECTION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; IMMUNOLOGICAL TOLERANCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THYMIC SELECTION; THYMOCYTE; TRANSGENICS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; AUTOIMMUNITY; CELL PROLIFERATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; IMMUNE SYSTEM; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; THYMOCYTES; THYMUS GLAND;

EID: 84870512578     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.295     Document Type: Article

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